INDICATOR COMPONENTS
The InsiderStreet Score combines six investment factors: Earnings Quality, Financial Quality, Relative Valuation, Risk/Safety, Price Momentum, and Insider/Smart-Money Trading. Scored 1–10, ranked vs sector peers. Weights: Quality 35%, Value 30%, Momentum 12%, with 22% weight on InsiderStreet's proprietary Insider/Smart-Money factor — the data layer that distinguishes us from generic equity research.
OPTIMIZED SCORE
The Optimized Score uses backtested factor weightings derived from historical return attribution. For large/mid cap stocks, Financial Quality and Earnings provide the most explanatory power. For small/micro cap, Insider Trading and Momentum dominate. Companies with Optimized Score ≥ 7 have historically outperformed over 12 months.
PEER ANALYSIS
Currency in USD
| Score | Ticker | Price |
1-Mo | 3-Mo | 1-Yr |
Mkt Cap | Trail PE |
Net Mgn | Edge |
Piotroski | Alpha Radar |
| 3 |
MNPR |
$59.77 |
-3.7% |
+2.6% |
+71.2% |
$0.4B |
-34.0 |
-- |
28.4 |
2 |
0 |
| 5 |
NVO |
$43.88 |
-6.4% |
+15.7% |
-44.1% |
$195.0B |
-- |
37.2% |
-- |
5 |
-1 |
| 5 |
VRTX |
$444.93 |
-0.7% |
-6.9% |
-1.4% |
$112.9B |
-- |
35.4% |
57.4 |
5 |
0 |
| 5 |
REGN |
$612.14 |
-15.4% |
-18.2% |
+17.0% |
$63.1B |
-- |
29.6% |
51.9 |
5 |
-2 |
| 5 |
ARGX |
$893.52 |
+10.6% |
+26.8% |
+56.2% |
$55.3B |
-- |
33.4% |
62.3 |
5 |
3 |
| 7 |
ALNY |
$282.85 |
-0.9% |
-8.8% |
-4.3% |
$37.8B |
-- |
13.5% |
53.9 |
7 |
-1 |
| 1 |
RVMDW |
$5.94 |
+3.3% |
+229.4% |
+1867.9% |
$36.1B |
-- |
-- |
34.1 |
1 |
0 |
| 1 |
RVMD |
$153.87 |
+2.4% |
+57.0% |
+255.5% |
$32.7B |
-- |
-- |
33.8 |
1 |
0 |
| 7 |
RPRX |
$54.87 |
+7.4% |
+20.5% |
+66.6% |
$23.6B |
-- |
33.9% |
46.8 |
7 |
2 |
PEER COMPANIES
| NVO | Novo Nordisk A/S |
VRTX | Vertex Pharmaceuticals Incorporated |
| REGN | Regeneron Pharmaceuticals, Inc. |
ARGX | argenx SE |
| ALNY | Alnylam Pharmaceuticals, Inc. |
RVMDW | Revolution Medicines, Inc. Warrant |
| RVMD | Revolution Medicines, Inc. |
RPRX | Royalty Pharma plc |
| UTHR | United Therapeutics Corporation |
NEGATIVE OUTLOOK: Earnings quality score of 0 signals unreliable earnings.
Last 8 Quarters — EPS Surprises
| Date | EPS Est | EPS Actual | Surprise |
|---|
| 2026-05-14 00:00:00 |
$-1.06 |
$-0.46 |
+56.6% |
| 2026-03-27 00:00:00 |
$-0.51 |
$-0.61 |
-19.1% |
| 2025-11-13 00:00:00 |
$-0.46 |
$-0.48 |
-4.3% |
| 2025-08-12 00:00:00 |
$-0.47 |
$-0.35 |
+25.5% |
| 2025-05-13 00:00:00 |
$-0.65 |
$-0.38 |
+41.5% |
| 2025-03-31 00:00:00 |
$-0.36 |
$-2.23 |
-519.4% |
| 2024-11-08 00:00:00 |
$-0.46 |
$-0.37 |
+19.6% |
| 2024-08-09 00:00:00 |
$-0.45 |
$-0.50 |
-11.1% |
Surprise Stats (Last 8 Q)
| # Positive Surprises (>2%) | 4 |
| # Negative Surprises (<-2%) | 4 |
| # In-Line (within ±2%) | 0 |
| Avg Surprise | -51.3% |
Analyst Consensus
| Strong Buy | 0 |
| Buy | 11 |
| Hold | 2 |
| Sell | 0 |
| Strong Sell | 0 |
| Consensus | Buy |
HIGHLIGHTS
- – Edge Score (earnings quality) is 0, the lowest rating in InsiderStreet’s framework.
- – Quarterly surprises have swung from +56.6% to ‑519.4% over the last eight quarters, indicating extreme earnings volatility.
- – The most recent surprise (May 14 2026) was +56.6%, far above expectations.
- – Analyst consensus is a “Buy” (11 Buy, 2 Hold), but the zero earnings quality undermines confidence.
PRICE TARGET
Mean Target (last Q)
$105.00
EARNINGS PER SHARE
Quarterly EPS: Actual vs Estimated
Annual Summary (5Y)
| Year | Revenue | Net Income | EPS |
|---|
| 2025 |
-- |
$-0.0B |
$-1.85 |
| 2024 |
-- |
$-0.0B |
$-1.36 |
| 2023 |
-- |
$-0.0B |
$-0.58 |
| 2022 |
-- |
$-0.0B |
$-0.83 |
| 2021 |
-- |
$-0.0B |
$-0.73 |
ANALYST RECOMMENDATIONS
I/B/E/S Mean: Buy (13 Analysts)
EARNINGS SURPRISES (Last 6)
| Type | Date | Actual | Est | Δ |
|---|
| Positive |
2026-05-14 00:00:00 |
$-0.46 |
$-1.06 |
+56.6% |
| Negative |
2026-03-27 00:00:00 |
$-0.61 |
$-0.51 |
-19.1% |
| Negative |
2025-11-13 00:00:00 |
$-0.48 |
$-0.46 |
-4.3% |
| Positive |
2025-08-12 00:00:00 |
$-0.35 |
$-0.47 |
+25.5% |
| Positive |
2025-05-13 00:00:00 |
$-0.38 |
$-0.65 |
+41.5% |
| Negative |
2025-03-31 00:00:00 |
$-2.23 |
$-0.36 |
-519.4% |
ANNUAL REVENUE & NET INCOME
Trailing revenue trajectory and operating leverage. Patterns of revenue growth with rising net income indicate strong execution.
| Latest Revenue (FY) | $0.0B |
| Revenue Growth YoY | +0.0% |
| Revenue CAGR (4Y) | +0.0% |
| EPS Growth YoY | +36.0% |
VALUATION HISTORY
NEUTRAL OUTLOOK:
5-Year history of valuation multiples by quarter. Each chart shows the trailing value of the multiple and the 5-year average.
PRICE TO EARNINGS
Close price ÷ TTM EPS.
Current: -34.0 · 5Y Avg: -17.3
PRICE TO SALES
Close price ÷ revenue per share.
Current: -- · 5Y Avg: --
PRICE TO BOOK
Close price ÷ book value per share.
Current: 0.0 · 5Y Avg: 8.5
PEG RATIO
P/E ÷ EPS growth rate.
Current: -- · 5Y Avg: --
EV / EBITDA
Enterprise value ÷ EBITDA.
Current: 3544.0 · 5Y Avg: 359.0
EV / FCF (TTM)
Enterprise value ÷ free cash flow.
-34.8
EV / FCF (TTM)
FCF Yield: -2.9%
NEUTRAL OUTLOOK: Elevated beta (1.539) offsets a strong Altman Z‑Score (92.64).
Volatility & Beta
52W High Distance-43.1%
vs 52W high
52W Low Distance+104.8%
vs 52W low
ATR (14)$3.86
Average True Range
Financial Safety
Altman Z-Score92.64
Safe Zone
Piotroski F-Score2/9
Quality screen
Current Ratio56.04
Liquidity
Debt-to-Equity0.00
Leverage
PEER RISK COMPARISON
| Ticker | 1W Ret | 1M Ret | 3M Ret | 1Y Ret | Piotroski | Mkt Cap |
|---|
| MNPR |
-0.9% |
-3.7% |
+2.6% |
+71.2% |
2 |
$0.4B |
| NVO |
-- |
-6.4% |
+15.7% |
-44.1% |
5 |
$195.0B |
| VRTX |
-- |
-0.7% |
-6.9% |
-1.4% |
5 |
$112.9B |
| REGN |
-- |
-15.4% |
-18.2% |
+17.0% |
5 |
$63.1B |
| ARGX |
-- |
+10.6% |
+26.8% |
+56.2% |
5 |
$55.3B |
| ALNY |
-- |
-0.9% |
-8.8% |
-4.3% |
7 |
$37.8B |
| RVMDW |
-- |
+3.3% |
+229.4% |
+1867.9% |
1 |
$36.1B |
| RVMD |
-- |
+2.4% |
+57.0% |
+255.5% |
1 |
$32.7B |
HIGHLIGHTS
- – Beta of 1.539 indicates the stock is ~54% more volatile than the market.
- – Altman Z‑Score of 92.64 signals robust financial health.
- – Piotroski F‑Score of 2 points to weak accounting fundamentals.
- – 1‑year total return of 71.25% shows recent price strength.
PRICE MOMENTUM & EQUITY WEATHER
NEGATIVE OUTLOOK: Momentum is weak, with an Edge Score of 3.6 and a rainy weather label.
Equity Weather (composite)
Alpha Radar Opinion
Opinion 0/100
As of 2026-06-10 00:00:00
SCREENS HIT
squeeze_bearish
SEASONALITY — Monthly Avg Return (12 months)
| Month | Avg Return | Median | Win Rate | N |
|---|
| January |
+19.6% |
-8.5% |
4286% |
7 |
| February |
+6.7% |
-8.2% |
2857% |
7 |
| March |
-15.0% |
-21.1% |
2857% |
7 |
| April |
-1.9% |
-3.2% |
3333% |
6 |
| May |
-6.4% |
-5.9% |
1667% |
6 |
| June |
+0.8% |
-0.6% |
5000% |
6 |
| July |
-2.6% |
-7.4% |
3333% |
6 |
| August |
-15.6% |
-13.7% |
0% |
6 |
| September |
+49.7% |
-2.9% |
3333% |
6 |
| October |
+34.4% |
+3.0% |
6667% |
6 |
| November |
+1.3% |
-0.6% |
5000% |
6 |
| December |
-9.3% |
-10.2% |
2857% |
7 |
HIGHLIGHTS
INSIDER TRADING (FORM 4 & FORM 144)
NEUTRAL OUTLOOK:
Last 90 Days — Summary
Total Form 4 Transactions6
Recent Form 4 Transactions (Top 10 by Date)
| Date | Insider | Role | Type | A/D | Shares | Price |
|---|
| 2026-03-31 |
Robinson Chandler |
director, officer: |
M-Exem |
SELL |
6,732 |
$0.00 |
| 2026-03-31 |
Robinson Chandler |
director, officer: |
M-Exem |
BUY |
6,732 |
$0.00 |
| 2026-03-31 |
Robinson Chandler |
director, officer: |
F-InKi |
SELL |
1,972 |
$54.79 |
| 2026-03-31 |
Cittadine Andrew |
officer: Chief Ope |
M-Exem |
BUY |
3,514 |
$0.00 |
| 2026-03-31 |
Cittadine Andrew |
officer: Chief Ope |
F-InKi |
SELL |
1,571 |
$54.79 |
| 2026-03-31 |
Cittadine Andrew |
officer: Chief Ope |
M-Exem |
SELL |
3,514 |
$0.00 |
| 2026-03-02 |
Rodriguez Susan |
officer: CCSO |
A-Awar |
BUY |
48,728 |
$53.47 |
| 2026-03-02 |
Rodriguez Susan |
officer |
|
SELL |
0 |
$0.00 |
| 2026-01-01 |
RIOUX PATRICE |
other: Acting Chie |
A-Awar |
BUY |
2,000 |
$65.30 |
| 2025-12-31 |
Robinson Chandler |
director, officer: |
M-Exem |
SELL |
8,724 |
$0.00 |
FORM 144 — Planned Sales (Forward-Looking Signal)
| Filing Date | Filer | Security | Shares to Sell | Estimated Proceeds |
|---|
| 2025-12-19 |
Arthur Klausner |
Class A |
5,121 |
$0.34M |
| 2025-07-14 |
Robinson Chandler |
Common |
16,800 |
$0.67M |
| 2025-07-14 |
Tsuchimoto Kim R |
Common |
8,904 |
$0.36M |
| 2025-07-14 |
STARR CHRISTOPHER M |
Common |
16,800 |
$0.67M |
| 2025-04-02 |
Tactic Pharma LLC |
Common |
33,334 |
$1.17M |
HIGHLIGHTS
POLITICAL TRADING (HOUSE + SENATE)
NEUTRAL OUTLOOK: No congressional trades in MNPR were recorded.
RECENT HOUSE TRADES
No recent House trades.
RECENT SENATE TRADES
No recent Senate trades.
HIGHLIGHTS
- – 0 House members reported buys or sells of MNPR in the past year.
- – 0 Senate members reported buys or sells of MNPR in the past year.
- – No recent House trades for MNPR were identified.
- – No recent Senate trades for MNPR were identified.
INSTITUTIONAL OWNERSHIP (13F)
NEGATIVE OUTLOOK: Institutional ownership is effectively nonexistent, with zero 13F shares held.
As of 2024-Q3
Latest Complete Quarter
Total 13F Filers Holding--
Total Notional Invested--
Q-o-Q Changes (Position Counts)
TOP 10 INSTITUTIONAL HOLDERS
HIGHLIGHTS
- – Investors holding 0 shares as of 2024‑Q3 (InvestorsHolding = 0).
- – Total invested amount is $0.0 (TotalInvested = 0.0).
- – 12 positions were closed in the latest quarter, with no new, increased, or reduced positions
ETF FLOWS · DARK POOL · SHORT INTEREST
NEUTRAL OUTLOOK: ETF inflows are positive and short interest remains modest.
Short Interest — 30 Days
Avg Daily Short Vol10,764
Avg Total Daily Vol16,579
HIGHLIGHTS
- – ETF net accumulation stands at 71.
- – 160 ETFs are increasing versus 89 decreasing.
- – Short interest averages 0.68% of float.
- – Dark‑pool activity data is unavailable.
ALPHA RADAR — TECHNICAL DEEP DIVE
NEUTRAL OUTLOOK:
Oscillators & Momentum
TSI (True Strength Index)1.95
PIVOT POINTS (Classic Daily)
SCREENS CURRENTLY TRIGGERED (1)
squeeze_bearish
HIGHLIGHTS
NEWS, EVENTS & SENTIMENT
NEUTRAL OUTLOOK:
Recent News (Last 30 Days, Top 7)
RECENT FORM 8-K EVENTS
| Filing Date | Form | Items | Description |
|---|
| 2026-05-29 |
8-K |
<built-in method items of dict object at 0x7c82caae2bc0> |
Regulation FD; Exhibits |
| 2026-05-19 |
8-K |
<built-in method items of dict object at 0x7c82caae2dc0> |
Regulation FD; Exhibits |
| 2026-05-14 |
8-K |
<built-in method items of dict object at 0x7c82caae2ec0> |
Earnings Release; Exhibits |
| 2026-04-20 |
8-K |
<built-in method items of dict object at 0x7c82caae2f80> |
Regulation FD; Exhibits |
| 2026-03-27 |
8-K |
<built-in method items of dict object at 0x7c82caae3080> |
Earnings Release; Exhibits |
| 2026-03-02 |
8-K |
<built-in method items of dict object at 0x7c82caae3180> |
Regulation FD Disclosure; Financial Statements and Exhibits |
| 2025-11-13 |
8-K |
<built-in method items of dict object at 0x7c82caae3240> |
Results of Operations and Financial Condition; Financial Sta |
| 2025-11-10 |
8-K |
<built-in method items of dict object at 0x7c82caae3300> |
Regulation FD Disclosure; Financial Statements and Exhibits |
RECENT SCHEDULE 13D/G ACTIVIST FILINGS
| Filing Date | Form | Is 13D | Issuer |
|---|
| 2026-05-15 |
SCHEDULE 13G |
NO |
Monopar Therapeutics Inc. |
| 2026-05-13 |
SCHEDULE 13G/A |
NO |
Monopar Therapeutics |
| 2026-02-17 |
SCHEDULE 13G/A |
NO |
Monopar Therapeutics Inc. |
| 2026-02-06 |
SCHEDULE 13G/A |
NO |
Monopar Therapeutics Inc. |
| 2026-01-30 |
SCHEDULE 13D/A |
YES |
Monopar Therapeutics |
HIGHLIGHTS
METHODOLOGY
InsiderStreet Score (0-10). Composite of six factors: Earnings Quality (18%), Financial Quality (18%), Relative Valuation (15%), Risk/Safety (15%), Price Momentum (12%), Insider/Smart-Money (22%). Each factor is independently scored 0-10 from underlying data, then weighted into the composite. Stocks with composite ≥7 have historically outperformed the S&P 500 over rolling 12-month windows.
Edge Score. InsiderStreet's proprietary competitive-advantage score (0-100), built from five sub-pillars: Cost Advantage, Intangibles, Switching Costs, Network Effects, and Scale. Ratings: Wide (≥70), Narrow (40-69), Limited (<40).
Insider/Smart-Money Factor. The differentiator. Built from Form 4 (corporate insider) transactions, Form 144 (planned sales), 13F (institutional) Q-o-Q changes, ETF accumulation, Congressional (House + Senate) trades, dark pool weekly notional, and FINRA short volume. Each input is percentile-ranked vs sector; composite re-percentile-ranked vs market.
Data Freshness. 13F filings are due 45 days after quarter-end. If the latest quarter's filing window is open AND we have less than 90% of prior-quarter filer count, we suppress Q-o-Q comparisons and label the data as in-progress.
Fair Value. Three models: Conservative EPS (P/E reversion to historical norm), Base Growth (forward EPS × industry mean P/E), Optimistic Growth (analyst-implied price target). Final fair value range presented; current price compared to base.
DATA SOURCES & CADENCE
| Data | Source | Cadence | Lag |
|---|
| Stock Quotes | Polygon, FMP | Real-time / 15-min | 0-15 min |
| Form 4 (Insiders) | SEC EDGAR | Daily | 0-2 days |
| Form 144 (Planned Sales) | SEC EDGAR | Daily | 0-2 days |
| Form 8-K (Events) | SEC EDGAR | Daily | 0-2 days |
| 13F (Institutional) | SEC EDGAR | Quarterly | Up to 45 days post Q-end |
| Schedule 13D/G | SEC EDGAR | Event-driven | 10 days from trigger |
| House Trades | House Financial Disclosures | Daily | 30-45 days from txn |
| Senate Trades | Senate eFD | Daily | 30-45 days from txn |
| Dark Pool | FINRA ATS | Weekly | ~14 days |
| Short Interest | FINRA Daily Short Sale Vol | Daily | 1-2 days |
| Earnings + Analyst Est | FMP, Refinitiv | Quarterly + ad-hoc | 0-3 days |
| News + Sentiment | 200+ outlets, AI-scored | 15-min | 0-15 min |
| ETF Holdings | SEC N-PORT, ETF.com | Monthly / Quarterly | 30-45 days |
| Technical Indicators | Computed daily | Daily | 0-1 day |
DISCLAIMER
This report is generated by InsiderStreet.ai for informational and educational purposes only. It does not constitute investment advice, a recommendation to buy or sell any security, or an offer of any financial product or service. Past performance does not guarantee future results.
All scores, ratings, and analyses are derived from public data sources including SEC filings (EDGAR), FINRA disclosures, exchange data, and analyst estimate aggregators. While we strive for accuracy, data may contain errors or be subject to revision by source providers. Users should verify all material information independently before making investment decisions.
"Edge Score", "InsiderStreet Score", "Capital Discipline", and "Conviction" are proprietary terms developed by InsiderStreet.ai and are not affiliated with any third-party rating services.
Generated 2026-06-15 04:23:30 ET · Cached 24h · Refresh: ?refresh=1