| Profitability | 88/100 |
| Growth | 74/100 |
| Momentum | 91/100 |
| Quality | 69/100 |
| Earnings Quality | 67/100 |
| Balance Sheet | 41/100 |
| Value | 43/100 |
| Risk (safety) | 50/100 |
| Overall | 67.3/100 |
| Symbol | IS Score |
|---|---|
| AZN | 71 |
| GILD | 44 |
| NVS | 65 |
| PFE | 46 |
| MRK | 49 |
| BMY | 68 |
| AMGN | 67 |
Both readings sit above the midpoint — business quality at 67 and price structure at 92 out of 100 — so they are not in conflict. The fundamentals and the tape are saying the same thing, which is the case in which either one alone would have been enough.
| Trigger | Where it stands now | What it would mean |
|---|---|---|
| IS Score reaches 75 and holds two consecutive quarters | now 67.3 | would move us up one band |
| IS Score stops falling - one quarter higher than the prior | last four: 61 → 63 → 65 → 67 | the direction matters more than the level |
| Technical vote share back above 50% | now 100% | price structure no longer broken |
| Institutional holder count rises two quarters running | peak 3,172 → now 3,172 | fewer institutions willing to hold is our clearest warning |
This page is InsiderStreet's own reading, produced from the data in the rest of this document. It is not a price target and not investment advice. Analyst consensus and street price targets appear later under their own heading and are the street's numbers, not ours.
| Quarter | Holders | 13F shares | Value | Reported own% |
|---|---|---|---|---|
| 2026 Q2 | 3,172 | 462.0M | $164.3B | 85.6% |
| 2026 Q1 | 3,153 | 435.2M | $151.5B | 80.6% |
| 2025 Q4 | 3,103 | 444.0M | $143.5B | 82.2% |
| 2025 Q3 | 2,827 | 423.1M | $118.1B | 78.3% |
| 2025 Q2 | 2,866 | 432.8M | $119.6B | 80.2% |
| 2025 Q1 | 2,939 | 429.0M | $132.1B | 79.4% |
| 2024 Q4 | 2,868 | 418.5M | $107.5B | 77.5% |
| 2024 Q3 | 2,831 | 410.1M | $129.5B | 75.9% |
| 2024 Q2 | 2,796 | 413.4M | $127.2B | 76.5% |
| 2024 Q1 | 2,726 | 409.9M | $114.7B | 75.9% |
| 2023 Q4 | 2,725 | 410.9M | $116.2B | 76.1% |
| 2023 Q3 | 2,512 | 406.4M | $107.5B | 75.2% |
| Insider | Role | Date | Type | Shares | Value | Post-Txn Owned |
|---|---|---|---|---|---|---|
| Dittrich Thomas J.W. | EVP & CFO | 2026-09-04 | — | 17,201 | $7.07M | 0 |
| Khosla Rachna | SVP, Business Development | 2026-08-13 | EXERCISE | 1,252 | $0.20M | 7,656 |
| Khosla Rachna | SVP, Business Development | 2026-08-13 | SELL | 1,252 | $0.52M | 6,404 |
| Khosla Rachna | SVP, Business Development | 2026-08-13 | EXERCISE | 1,252 | $0.20M | 0 |
| Khosla Rachna | SVP, Business Development | 2026-08-11 | SELL | 2,000 | $0.83M | 6,404 |
| Busch Matthew C. | VP, Finance & CAO | 2026-08-07 | A-Award | 730 | — | 5,080 |
| Ishrak Omar | director | 2026-08-07 | A-Award | 85 | — | 7,486 |
| Holley Charles M | director | 2026-08-07 | A-Award | 103 | — | 12,990 |
| 6-mo decomposition (Form 4) | Txns | Shares | Value | Signal weight |
|---|---|---|---|---|
| S — Open-market sales | 6 | 31,601 | $12.1M | Counted |
| M — Exercises (paired A/D) | 8 | 182,686 | $29.4M | None — mechanics |
| F — Tax withholding | 53 | 161,838 | $59.5M | None — compensation |
| P — Open-market purchases | 0 | 0 | $0 | Counted — none occurred |
| Filed | Filer | Shares registered | Est. proceeds |
|---|---|---|---|
| 2026-08-13 | Khosla Rachna | 1,252 | $0.5M |
| 2026-08-11 | Khosla Rachna | 2,000 | $0.8M |
| 2026-08-06 | Grygiel Nancy A. | 2,970 | $1.2M |
| 2026-08-06 | Derek Miller | 3,890 | $1.6M |
| Trailing 12 mo | 11 filings | 80,719 | $31M |
| Filed | Form | Reporting person | % of class | Shares |
|---|---|---|---|---|
| 2026-05-14 | SCHEDULE 13G | Capital World Investors | 5.50% | 29.6M sh |
| 2026-03-26 | SCHEDULE 13G/A | The Vanguard Group | — | exit/reporting change |
| 2025-09-08 | SCHEDULE 13G/A | The Vanguard Group | 10.00% | 53.9M sh |
| 2025-04-17 | SCHEDULE 13G/A | BlackRock, Inc. | 7.60% | 40.8M sh |
| Member | Chamber | Trade | Size band | Traded | Disclosed |
|---|---|---|---|---|---|
| David Taylor | House | BUY | $1,001 - $15,000 | 2026-09-22 | 2026-10-02 |
| Ro Khanna | House | BUY | $1,001 - $15,000 | 2026-09-04 | 2026-10-09 |
| David Taylor | House | SELL | $1,001 - $15,000 | 2026-08-26 | 2026-09-07 |
| Sheldon Whitehouse | Senate | SELL | $1,001 - $15,000 | 2026-08-12 | 2026-09-02 |
| Sheldon Whitehouse | Senate | SELL | $1,001 - $15,000 | 2026-08-12 | 2026-09-02 |
| Sheldon Whitehouse | Senate | SELL | $1,001 - $15,000 | 2026-08-12 | 2026-09-01 |
| Manager | Shares | Value |
|---|---|---|
| Assenagon Asset Management S.A. | 1.1M | $455M |
| Smead Capital Management, Inc. | 586,504 | $247M |
| Forum Financial Management, Lp | 347,857 | $147M |
| Wealth Enhancement Advisory Servic | 340,323 | $109M |
| Ferguson Wellman Capital Managemen | 243,747 | $103M |
| Sarasin & Partners Llp | 180,232 | $76M |
| Fund | Weight | Position |
|---|---|---|
| VITSX | 0.3% | $7.2B |
| VTSAX | 0.3% | $7.2B |
| VSMPX | 0.3% | $7.2B |
| VTI | 0.3% | $7.2B |
| VFINX | 0.3% | $6.0B |
| VFFSX | 0.3% | $6.0B |
| ATS Venue (4-wk) | Shares | Avg trade |
|---|---|---|
| Incr Intelligent Cross Llc | 2.9M | 32 sh |
| Ubsa Ubs Ats | 2.6M | 37 sh |
| Sgmt Sigma X2 | 1.5M | 27 sh |
| Ebxl Level Ats | 1.5M | 20 sh |
| Mlix Instinct X | 1.4M | 42 sh |
| Bids Bids Ats | 1.3M | 345 sh |
| Region | Revenue | Share |
|---|---|---|
| UNITED STATES | $26.4B | 72% |
| Non-US | $10.3B | 28% |
Moat score 58/100 — Narrow; primary source Efficient Scale.
| Officer | Title |
|---|---|
| Robert A. Bradway | Chairman & CEO |
| James E. Bradner | EVP of Research & Development, Artificial Intelligence and Data |
| Peter H. Griffith | Executive Vice President |
| Thomas J. W. Dittrich | Executive Vice President & Chief Financial Officer |
| Period | EPS est. | EPS actual | EPS surprise | Rev est. ($M) | Rev actual ($M) | Rev surprise |
|---|
| YoY growth | FY21 | FY22 | FY23 | FY24 | FY25 |
|---|---|---|---|---|---|
| Revenue | +2.2% | +1.3% | +7.1% | +18.6% | +9.9% |
| Gross profit | +1.3% | +2.0% | -0.7% | +4.0% | +26.5% |
| Operating income | -16.4% | +25.2% | -17.4% | -8.1% | +47.1% |
| Net income | -18.9% | +11.2% | +2.5% | -39.1% | +88.5% |
| $B · FY ends | FY21 | FY22 | FY23 | FY24 | FY25 | Trend |
|---|---|---|---|---|---|---|
| Revenue | 26.0 | 26.3 | 28.2 | 33.4 | 36.7 | |
| Cost of revenue | 6.5 | 6.4 | 8.4 | 12.9 | 10.7 | |
| Gross profit | 19.5 | 19.9 | 19.8 | 20.6 | 26.0 | |
| R&D expense | 6.3 | 4.4 | 4.8 | 6.0 | 7.0 | |
| SG&A expense | 5.4 | 5.4 | 6.2 | 7.1 | 7.1 | |
| Operating income | 7.6 | 9.6 | 7.9 | 7.3 | 10.7 | |
| EBITDA | 11.3 | 12.2 | 14.8 | 13.4 | 15.8 | |
| D&A | 3.4 | 3.4 | 4.1 | 5.6 | 5.2 | |
| Pretax income | 6.7 | 7.3 | 7.9 | 4.6 | 9.0 | |
| Income tax | 0.8 | 0.8 | 1.1 | 0.5 | 1.3 | |
| Net income | 5.9 | 6.6 | 6.7 | 4.1 | 7.7 | |
| Diluted EPS ($) | 10.28 | 12.11 | 12.49 | 7.56 | 14.23 | |
| Diluted shares (M) | 573 | 541 | 538 | 541 | 542 |
| $B | FY22 | FY23 | FY24 | FY25 | |
|---|---|---|---|---|---|
| Cash & equivalents | 7.6 | 10.9 | 12.0 | 9.1 | |
| ST investments | 1.7 | 0.0 | 0.0 | 0.0 | |
| Receivables (net) | 6.4 | 7.9 | 7.5 | 9.6 | |
| Total current assets | 22.2 | 30.3 | 29.0 | 29.1 | |
| PP&E (net) | 5.4 | 5.9 | 6.5 | 7.9 | |
| Goodwill + intangibles | 31.6 | 51.3 | 46.3 | 41.0 | |
| Total assets | 65.1 | 97.2 | 91.8 | 90.6 | |
| Accounts payable | 1.6 | 1.6 | 1.9 | 20.9 | |
| Short-term debt | 1.6 | 1.4 | 3.6 | 4.6 | |
| Deferred revenue | 0.0 | 0.0 | 0.0 | 0.0 | |
| Total current liabilities | 15.7 | 18.4 | 23.1 | 25.5 | |
| Long-term debt | 37.4 | 63.2 | 56.5 | 50.0 | |
| Total liabilities | 61.5 | 90.9 | 86.0 | 81.9 | |
| Shareholders' equity | 3.7 | 6.2 | 5.9 | 8.7 |
| $B | FY22 | FY23 | FY24 | FY25 | |
|---|---|---|---|---|---|
| Net income | 6.6 | 6.7 | 4.1 | 7.7 | |
| D&A | 3.4 | 4.1 | 5.6 | 5.2 | |
| Stock-based compensation | 0.4 | 0.4 | 0.5 | 0.0 | |
| Working capital change | (0.7) | (0.5) | 2.4 | (2.0) | |
| Operating cash flow | 9.7 | 8.5 | 11.5 | 10.0 | |
| Capital expenditures | (0.9) | (1.1) | (1.1) | (1.9) | |
| Investing cash flow | (6.0) | (26.2) | (1.0) | (1.9) | |
| Buybacks | (6.4) | 0.0 | (0.2) | 0.0 | |
| Dividends paid | (4.2) | (4.6) | (4.8) | (5.1) | |
| Debt issuance / (repay) | 6.6 | 25.7 | (4.3) | (5.7) | |
| Financing cash flow | (4.0) | 21.0 | (9.4) | (10.9) | |
| Free cash flow | 8.8 | 7.4 | 10.4 | 8.1 |
| Ratio | FY21 | FY22 | FY23 | FY24 | FY25 | TTM | Trend |
|---|---|---|---|---|---|---|---|
| PROFITABILITY | |||||||
| ROE | 73.2% | 126.5% | 135.8% | 67.6% | 106.1% | 89% | |
| ROA | 9.5% | 10.4% | 8.3% | 4.3% | 8.5% | 9.1% | |
| ROIC | 21.0% | 25.6% | 11.3% | 11.9% | 16.3% | 14.2% | |
| Gross margin | 75.2% | 75.7% | 70.1% | 61.5% | 70.8% | 72.7% | |
| Operating margin | 29.4% | 36.3% | 28.0% | 21.7% | 29.1% | 33.2% | |
| Net margin | 22.7% | 24.9% | 23.8% | 12.2% | 21.0% | 22.9% | |
| EBITDA margin | 43.5% | 46.2% | 52.5% | 40.0% | 43.1% | 46.2% | |
| FCF margin | 32.3% | 33.4% | 26.1% | 31.1% | 22.0% | — | |
| VALUATION | |||||||
| P/E | 19.00 | 19.63 | 21.77 | 33.45 | 23.05 | 26.7 | |
| P/B | 16.71 | 35.13 | 23.46 | 23.28 | 20.53 | 20.0 | |
| P/S | 4.31 | 4.89 | 5.19 | 4.09 | 4.83 | 6.13 | |
| P/FCF | 13.36 | 14.64 | 19.87 | 13.16 | 21.94 | 23.0 | |
| EV/EBITDA | 12.15 | 13.01 | 13.50 | 13.85 | 13.20 | 15.7 | |
| EV/Revenue | 5.28 | 6.01 | 7.09 | 5.53 | 6.07 | 7.3 | |
| Earnings yield | 5.3% | 5.1% | 4.6% | 3.0% | 4.3% | 3.74% | |
| FCF yield | 7.5% | 6.8% | 5.0% | 7.6% | 4.6% | 4.35% | |
| Ratio | FY21 | FY22 | FY23 | FY24 | FY25 | TTM | Trend |
|---|---|---|---|---|---|---|---|
| LEVERAGE & SOLVENCY | |||||||
| Current ratio | 1.59 | 1.41 | 1.65 | 1.26 | 1.14 | 1.37 | |
| Quick ratio | 1.26 | 1.10 | 1.13 | 0.95 | 0.90 | 1.13 | |
| Debt / equity | 4.97 | 10.64 | 10.37 | 10.23 | 6.31 | 4.90 | |
| Debt / assets | 54.5% | 59.8% | 66.5% | 65.4% | 60.3% | 59.9% | |
| Net debt / EBITDA | 2.24 | 2.44 | 3.63 | 3.60 | 2.69 | 2.46 | |
| Interest coverage | 6.60 | 6.22 | 3.73 | 2.46 | 4.24 | — | |
| Ratio | FY21 | FY22 | FY23 | FY24 | FY25 | TTM | Trend |
|---|---|---|---|---|---|---|---|
| EFFICIENCY | |||||||
| Asset turnover | 0.42 | 0.42 | 0.35 | 0.35 | 0.40 | 0.40 | |
| Receivables turnover | 5.52 | 5.03 | 4.39 | 4.76 | 4.50 | 3.7 | |
| DSO (days) | 66 | 73 | 83 | 77 | 81 | 98 | |
| DPO (days) | 79 | 84 | 68 | 50 | 383 | 702 | |
| Cash conversion cycle | 213 | 246 | 327 | 261 | -80 | -386 | |
| GROWTH (YoY) | |||||||
| Revenue growth | 2.2% | 1.3% | 7.1% | 18.6% | 10.0% | — | |
| Net income growth | -18.9% | 11.2% | 2.5% | -39.1% | 88.5% | — | |
| EPS growth | -16.0% | 16.5% | 2.3% | -39.3% | 88.2% | — | |
| FCF growth | -15.2% | 4.8% | -16.2% | 41.2% | -22.1% | — | |
| PER SHARE ($) | |||||||
| EPS (diluted, TTM) | 10.43 | 12.16 | 12.44 | 7.55 | 14.20 | 16.19 | |
| Book value / share | 11.86 | 6.79 | 11.54 | 10.84 | 15.94 | 21.64 | |
| Revenue / share | 45.98 | 48.84 | 52.20 | 61.67 | 67.71 | 70.60 | |
| FCF / share | 14.83 | 16.30 | 13.63 | 19.18 | 14.92 | 18.84 | |
| Cash / share | 14.22 | 17.26 | 20.27 | 22.09 | 16.81 | 25.91 | |
| SHAREHOLDER RETURN & SCORES | |||||||
| Buyback yield | 4.4% | 4.9% | 0.0% | 0.1% | 0.0% | — | |
| Altman Z-Score | 1.66 | 1.61 | 1.38 | 1.25 | 2.18 | 2.3 | |
| Piotroski F-Score | 5 | 5 | 4 | 6 | 7 | 8/9 | |
| Beneish M-Score | -2.43 | -2.63 | -2.14 | -2.91 | -2.47 | -2.56 | |
| Model | Score | Zone | Note |
|---|---|---|---|
| Piotroski F-Score | 8 / 9 | Strong | |
| Altman Z-Score | 2.3 | Grey zone | Grey |
| Income quality | 1.43 | Cash-backed | OCF ÷ net income |
| Beneish M-Score | -2.56 | Non-manipulator | vs −2.22 threshold |
| DuPont Decomposition (TTM) | Value |
|---|---|
| Tax burden | 0.85 |
| Interest burden | 0.79 |
| Operating margin | 34.0% |
| Asset turnover | 0.42× |
| Financial leverage | 9.60× |
| = ROE | 91% |
| Growth Quality (live) | Value |
|---|---|
| Revenue stability | 0.90 |
| Earnings stability | 0.08 |
| Earnings persistence | 0.87 |
| Revenue CAGR 3y | 12.8% |
| EPS CAGR 3y | 2.7% |
| FCF CAGR 3y | 1.7% |
| Company | Mkt cap | P/E | ROE | Net margin | Rev growth | Piotroski | 1-yr ret |
|---|---|---|---|---|---|---|---|
| AZN | $256.5B | 24.7 | 22% | 16.3% | +8.6% | 9/9 | -1.5% |
| GILD | $193.7B | -60.1 | -21% | — | +5.5% | 5/9 | +33.4% |
| NVS | $286.3B | 22.9 | 31% | 22.7% | +0.8% | 5/9 | +15.1% |
| PFE | $168.6B | 39.1 | 5% | -1.6% | -0.2% | 7/9 | +24.2% |
| MRK | $360.1B | 115.8 | 7% | -8.0% | +4.5% | 4/9 | — |
| BMY | $122.1B | 13.2 | 47% | 25.6% | +3.1% | 8/9 | — |
| ABBV | $504.4B | 80.4 | -206% | 21.3% | +10.4% | 7/9 | — |
| JNJ | $615.9B | 38.7 | 26% | 21.9% | +8.1% | 7/9 | — |
| Consensus estimates | Revenue mean | High / Low | EPS mean | High / Low | # EPS est. |
|---|---|---|---|---|---|
| FY2026 | $39.00B | $39.55B / $38.54B | $23.04 | $23.32 / $22.59 | 20 |
| FY2027 | $40.45B | $41.94B / $39.15B | $24.51 | $26.03 / $22.82 | 19 |
| FY2028 | $41.78B | $47.20B / $38.09B | $25.90 | $29.24 / $21.03 | 11 |
| Window | Avg Target | vs. Price | # Targets |
|---|---|---|---|
| Last Month | $422.88 | -2.2% | 8 |
| Last Quarter | $404.64 | -6.4% | 25 |
| Last Year | $374.44 | -13.4% | 59 |
| All Time | $330.04 | -23.7% | 116 |
| Moving Average | Value | Distance | % Distance | Signal |
|---|---|---|---|---|
| SMA 20 | $413.39 | +19.10 | +4.62% | Above |
| SMA 50 | $414.52 | +17.97 | +4.34% | Above |
| SMA 200 | $365.67 | +66.82 | +18.27% | Above |
| EMA 9 | $421.08 | +11.41 | +2.71% | Above |
| EMA 21 | $414.51 | +17.98 | +4.34% | Above |
| EMA 50 | $406.49 | +26.00 | +6.40% | Above |
| EMA 200 | $368.77 | +63.72 | +17.28% | Above |
| Level | Value | Level | Value |
|---|---|---|---|
| Pivot / R1 / R2 | $436.40 / $439.39 / $444.74 | S1 / S2 | $431.05 / $428.06 |
| Bollinger (20,2) | $392.90 – $433.88 | Squeeze | Off |
| 52-wk range | $280.23 – $447.03 | Off 52-wk high | -3.2% |
| ATR (14) | $10.66 (2.5%) | Historical vol | 29.1% |
| Computed from live weekly prices | AMGN | S&P 500 |
|---|---|---|
| Weekly volatility (σ, 1y) | 3.90% | 1.83% |
| Best / worst week (1y) | +8.1% / -13.6% | — |
| Max drawdown (5y, monthly) | -21.6% | — |
| 1-week VaR (95%) | -4.6% | — |
| Beta (5y) | 0.43 | 1.00 |
| Reading | AMGN | Drug Manufacturers - General n=150 | Healthcare n=5,272 | All US symbols n=70,435 |
|---|---|---|---|---|
| Overall | +22.1 | -9.5 | -24.0 | -20.5 |
| Trend | +41.2 | -4.1 | -25.6 | -21.3 |
| Momentum | +53.3 | +9.9 | -28.5 | -15.8 |
| Volume | +42.4 | +16.6 | -25.0 | -3.8 |
| Executive | Total comp | Structure |
|---|---|---|
| Robert A. Bradway Chief Executive Officer an | $24.7M | 67% equity+incentive |
| James E. Bradner Executive Vice President, R | $8.6M | 58% equity+incentive |
| Peter H. Griffith Executive Vice President a | $8.6M | 62% equity+incentive |
| Murdo Gordon Executive Vice President, Globa | $8.5M | 63% equity+incentive |
| David M. Reese Executive Vice President and | $8.3M | 62% equity+incentive |
| Pillar (live disclosure scores) | Score |
|---|---|
| Environmental | 65 |
| Social | 52 |
| Governance | 67 |
| Composite ESG | 61 |
| Filed | 8-K contents | Items |
|---|---|---|
| 2026-08-04 | Earnings Release; Exhibits | 2.02,9.01 |
| 2026-07-31 | Other Events | 8.01 |
| 2026-05-20 | Shareholder Vote | 5.07 |
| 2026-05-19 | Officer/Director Change | 5.02 |
| 2026-04-30 | Earnings Release; Exhibits | 2.02,9.01 |
| 2026-04-22 | Officer/Director Change; Exhibits | 5.02,9.01 |
| 2026-02-19 | Entry into Material Definitive Agreement; Financial Statements and Exh | 1.01,9.01 |
| 2026-02-03 | Results of Operations and Financial Condition; Financial Statements an | 2.02,9.01 |
Methodology. Every figure originates in InsiderStreet's production data layer and is computed deterministically by the same engines that power insiderstreet.ai. This factsheet contains no model-written text. Sections without underlying data are omitted rather than estimated.
| Data domain | Source | Coverage for this report |
|---|---|---|
| Price & volume | market_db.historical_prices | 52 rows |
| Fundamentals | income_statements_annual | 6 rows · 2020 to 2025 |
| Reported vs consensus | fact/earnings_calendar | 24 rows · 2020-10-28 to 2026-08-04 |
| Analyst estimates | dim/forward_estimates | 3 rows · 2026-12-31 to 2028-12-31 |
| Institutional ownership (13F) | holdings_db.institutional_ownership_summary | 118 rows · 1997 to 2026 |
| Insider transactions (Form 4) | edgar/form4 | 12 rows · 2026-08-06 to 2026-09-04 |
| Proposed sales (Form 144) | edgar/form144 | 1 record |
| Beneficial ownership (13D/G) | edgar/13dg | 4 rows · 2025-04-17 to 2026-05-14 |
| Short-sale volume (FINRA) | edgar/short_volume_daily | 60 rows · 2026-07-23 to 2026-10-15 |
| Dark pool (ATS, tier 1) | edgar/darkpool_weekly | 12 rows · 2026-06-15 to 2026-08-31 |
| ETF & fund holding | etf_holdings_changelog (30d) | 1 record |
| Peer set | stock_peers_dynamic | 8 rows |
| Industry medians | industry_medians | 1 record |
| Congressional trades | congress_db (House + Senate) | 1 record |
| ESG | fact/esg_disclosures | 1 record |
Method. Every figure in this factsheet is looked up from a named field computed in code. It contains no model-written text.
Not covered. Short interest as a percent of float and days-to-cover are not in this data set — the short-sale figures above are FINRA volume, a flow, and cannot support squeeze or covering analysis. Options positioning and intraday data are also absent. 13F ownership is filed 45 days after quarter end and congressional trades are disclosed on a lag, so both describe a past position, not a current one.