NASDAQ · inception 2001-02-12 · beta 0.70 · avg volume 1,620,129 · holdings as of 2026-10-15 · prices through 2026-10-16
AUM$10.4B
Holdings234
Top-10 weight51.2%
1-yr return+31.8%
Max drawdown 5y-35.7%
Volatility 1y22.5%
Performance vs S&P 500 (SPY)
■ IBB■ SPY
Total return
1m
3m
6m
YTD
1y
3y
5y
IBB
-2.5%
+8.3%
+14.3%
+19.5%
+31.8%
+64.4%
+31.8%
SPY
+0.3%
+2.9%
+7.5%
+11.7%
+15.1%
+80.0%
+84.9%
Rebased to 100 five years ago, weekly adjusted closes. Max drawdown is the largest peak-to-trough fall in that window (trough 2022-06-16). 3y and 5y returns are cumulative.
Top holdings
#
Ticker
Name
Weight
1
GILD
GILEAD SCIENCES
8.62%
2
AMGN
AMGEN INC
8.14%
3
VRTX
VERTEX PHARMACEUTICALS
7.52%
4
MRNA
MODERNA
6.01%
5
REGN
REGENERON PHARMACEUTICALS
5.61%
6
NTRA
NATERA
3.86%
7
ARGX
ARGENX SE ADR
3.31%
8
ILMN
ILLUMINA INC
2.98%
9
RVMD
REVOLUTION MEDICINES
2.71%
10
BIIB
BIOGEN
2.48%
Exposure
Sector
Healthcare99.9%
Unclassified0.1%
Country
US86.8%
NL3.5%
CH2.7%
DK2.5%
GB1.5%
DE0.6%
CA0.6%
IE0.6%
FR0.5%
CN0.2%
Unclassified0.1%
Weights of holdings joined to company profiles; bonds, cash and derivatives fall under Unclassified.
InsiderStreet scores of the holdings
Holdings-weighted score
Score
Percentile vs ETFs
Overall
56/100
33
Quality
62/100
9
Profitability
54/100
26
Balance sheet
57/100
23
Earnings quality
52/100
2
Growth
56/100
36
Value
39/100
4
Momentum
65/100
6
Risk (safety)
84/100
65
Portfolio fundamentals
Value
P/E
43.5
P/B
8.9
P/S
7.4
Earnings yield
2.3%
FCF yield
4.1%
ROE
12.0%
Net margin
10.1%
Revenue growth (yoy)
+28.7%
Dividend yield
0.40%
Debt / equity
1.04
Scores are weighted by holding; 100% of the fund's weight is in companies we score. Percentile ranks the fund among ETFs with at least half their weight scored. A score describes the holdings, not the outlook for the fund.
Most similar ETFs by holdings overlap
ETF
Name
Overlap
Shared holdings
AUM
IBBQ
Invesco Nasdaq Biotechnology ETF
85.7%
206
$79.9M
BIB
ProShares Ultra Nasdaq Biotechnology
68.2%
207
$88.3M
BBH
VanEck Biotech ETF
65.2%
21
$486.7M
FBT
First Trust NYSE Arca Biotechnology Index Fund
44.3%
27
$1.6B
LABU
Direxion Daily S&P Biotech Bull 3X Shares
43.8%
122
$1.1B
XBI
State Street SPDR S&P Biotech ETF
43.8%
122
$7.5B
Overlap = sum over shared holdings of the smaller of the two weights.