SLNCF OTC
Credit Risk of going bust: lower than 69% of companies Debt: 0.0% of company value Bonds: none of note held by US funds details ▾
Total debt $112K against a stock market value of $934.3M.
Distance to default 7.45 (Merton model): prices to 2026-10-26, balance sheet 2026-06-30, debt counted $103K (short-term plus half of long-term), stock volatility 114.2%; Altman Z'' -16.28. A ranking and a back-test, not a forecast.
US fund filings (SEC N-PORT) show under $25M of this company's bonds, so there is no bond page. Its debt may be bank loans or privately placed. How these are computed.
London, GL W6 7AP
GB
Silence Therapeutics plc, a biotechnology firm headquartered in London, United Kingdom, is dedicated to the discovery and advancement of pioneering ribonucleic acid (RNA) therapeutics. Its research and development efforts span key areas such as blood disorders, cardiovascular health, and other uncommon and metabolic ailments. Central to the company's approach is its proprietary mRNAi GalNAc Oligonucleotide Discovery platform, meticulously crafted to precisely target specific disease-causing genes, predominantly within the liver. This mechanism involves creating short interfering RNA (siRNA) molecules that activate the body's intrinsic RNA interference pathway, effectively breaking down messenger RNA (mRNA) sequences responsible for producing particular disease-associated proteins inside cells. Silence Therapeutics is actively developing a pipeline of therapeutic candidates. This includes SLN360, currently in Phase I clinical trials for the treatment of cardiovascular disease characterized by elevated lipoprotein levels. Furthermore, SLN124 is progressing through Phase I clinical trials for both non-transfusion dependent thalassemia and myelodysplastic syndrome, with ongoing development also focused on polycythemia vera. The company has forged strategic partnerships to broaden its reach and capabilities. It collaborates with AstraZeneca PLC to identify, develop, and commercialize small interfering RNA therapeutics addressing cardiovascular, renal, metabolic, and respiratory conditions. Another alliance is with Mallinckrodt Pharma IP Trading DAC, centered on developing and marketing RNAi drug targets designed to inhibit the complement cascade in various complement-mediated disorders. Additionally, Silence Therapeutics is working with Hansoh Pharmaceutical Group Company Limited to develop siRNAs for three confidential targets, utilizing its mRNAi GOLD platform. The organization, which operated as SR Pharma plc until its rebranding in May 2007, continues its mission under the name Silence Therapeutics plc.