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XBI

State Street SPDR S&P Biotech ETF
1W: -0.4% 1M: -6.6% 3M: -3.9% YTD: +27.1% 1Y: +52.4% 3Y: +109.2% 5Y: +18.7%
$154.43
-0.08 (-0.05%)
 
Weekly Expected Move ±3.6%
$143 $149 $154 $160 $165
ETF AMEX · AUM $8.1B
Key Statistics
AUM$8.1B
Holdings159
Top 10 Wt16.7%
Volume8,732,783
Avg Volume8,848,691
Beta1.10
Portfolio Fundamentals
P/E54.9
P/B10.4
Div Yield0.12%
ROE4.7%
% Profitable18%
Inception2006-02-06
Sector Allocation
Healthcare 99.1%
Financial Services 0.7%
Other 0.2%
Top 10 Holdings
# Name Ticker Weight % Market Value Shares
1 TWIST BIOSCIENCE CORP TWST 2.21% $232.0M 1,177,281
2 MODERNA INC MRNA 2.04% $214.0M 1,089,652
3 NATERA INC NTRA 1.80% $188.6M 447,420
4 IOVANCE BIOTHERAPEUTICS INC IOVA 1.62% $170.0M 11,251,093
5 AMGEN INC AMGN 1.55% $162.4M 377,675
6 BIOGEN INC BIIB 1.54% $161.5M 701,205
7 UNITED THERAPEUTICS CORP UTHR 1.54% $161.1M 291,574
8 ABBVIE INC ABBV 1.50% $157.1M 588,960
9 HALOZYME THERAPEUTICS INC HALO 1.48% $154.9M 1,375,999
10 SPYRE THERAPEUTICS INC SYRE 1.47% $154.3M 1,699,846

Recent Holding Changes

Date Holding Change Details
2026-10-02 KLRA Changed 1229859 → 1221869
2026-10-02 SPRY Changed 2189969 → 2175740
2026-10-02 CAPR Changed 1791172 → 1779527
2026-10-02 MNPR Changed 138164 → 137263
2026-10-02 BIIB Changed 705778 → 701205

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For informational purposes only. Not investment advice. Data sourced from SEC filings. Privacy Terms