— Know what they know.
Not Investment Advice

SBIO

ALPS Medical Breakthroughs ETF
1W: -2.5% 1M: -17.3% 3M: -13.4% YTD: +11.9% 1Y: +44.7% 3Y: +110.2% 5Y: +25.2%
$56.15
-0.49 (-0.87%)
 
Weekly Expected Move ±4.0%
$52 $54 $56 $58 $61
ETF AMEX · AUM $178.3M
Key Statistics
AUM$178M
Holdings101
Top 10 Wt30.2%
Volume59,406
Avg Volume40,125
Beta0.95
Portfolio Fundamentals
P/E162.6
P/B4.5
Div Yield—%
ROE-32.7%
% Profitable7%
Inception2014-12-30
Sector Allocation
Healthcare 100.0%
Other 0%
Financial Services -0.0%
Top 10 Holdings
# Name Ticker Weight % Market Value Shares
1 CG oncology Inc. CGON 3.94% $8.3M 117,456
2 Travere Therapeutics Inc. TVTX 3.48% $7.4M 124,893
3 Oruka Therapeutics Inc. ORKA 3.45% $7.3M 87,745
4 Definium Therapeutics Inc. DFTX 3.20% $6.8M 178,006
5 VeraDermics Inc. MANE 3.17% $6.7M 55,356
6 Dianthus Therapeutics Inc. DNTH 3.08% $6.5M 74,082
7 Edgewise Therapeutics Inc. EWTX 2.76% $5.8M 143,864
8 Relay Therapeutics Inc. RLAY 2.48% $5.2M 290,321
9 Ideaya Biosciences Inc. IDYA 2.32% $4.9M 127,829
10 Amylyx Pharmaceuticals Inc. AMLX 2.29% $4.8M 166,303

Recent Holding Changes

Date Holding Change Details
2026-10-02 USD Changed 31151 → 28941
2026-10-01 USD Changed 35312 → 31151
2026-09-28 KURA Changed 117026 → 117876
2026-09-28 MLYS Changed 116294 → 117144
2026-09-28 SRPT Changed 138944 → 139944

Sign in to InsiderStreet

You'll also get our free weekly newsletter with
smart money signals, market insights, and alpha ideas.
Unsubscribe anytime.

For informational purposes only. Not investment advice. Data sourced from SEC filings. Privacy Terms