JAGLX
Janus Henderson Global Life Sciences Fund
1W: +0.2%
1M: -7.1%
3M: -5.3%
YTD: -4.9%
1Y: +15.1%
3Y: +37.1%
5Y: +38.4%
$76.16
-0.35 (-0.46%)
ETF-Level Metrics
AUM$5.5B
Holdings82
Top 10 Wt39.3%
Beta0.83
% Profitable43%
Coverage95%
Portfolio Valuation
P/E1689.1
P/B386.5
P/S185.8
EV/EBITDA17.1
P/FCF2363.7
PEG55.07
Profitability & Returns
Gross Margin55.3%
Net Margin10.9%
ROE23.2%
ROA8.8%
ROIC19.9%
Div Yield1.20%
Leverage & Liquidity
Debt/Equity0.62
Debt/Assets0.23
Net Debt/EBITDA0.8x
Interest Cov11.0x
Current Ratio1.52
Quick Ratio1.17
Growth (YoY)
Revenue+32.8%
Net Income+38.9%
EPS+51.9%
FCF+51.7%
EBITDA+36.9%
Rev CAGR 3Y+28.3%
Quality Scores
Piotroski F6.2
Altman Z8.83
IS Quality70.9
IS Overall62.2
IS Value40.6
Median P/E13.9
Sector Breakdown
2 sectors| Sector | # Holdings | Total Weight % | Avg P/E |
|---|---|---|---|
| Healthcare | 82 | 97.8% | -88.1 |
| Other | 23 | 2.3% | — |
Smart Money Overlap
5 holdings with signals| Symbol | Company | Weight % | Signals | Badge | Insider Buys | Congress | Since Signal |
|---|---|---|---|---|---|---|---|
| JNJ | Johnson & Johnson | 5.01% | 4 | Bullish | 12 | 2 | -1.2% |
| BSX | Boston Scientific Corporation | 2.74% | 4 | Bullish | 8 | 6 | -5.3% |
| CVS | CVS Health Corporation | 1.65% | 4 | Bullish | 9 | 2 | -0.9% |
| HUM | Humana Inc. | 0.37% | 4 | Bullish | 1 | 2 | -3.4% |
| ILMN | Illumina, Inc. | 0.21% | 4 | Bullish | 12 | 1 | -3.0% |
Showing 50 of 105 holdings
· Page 1 of 3
| # | Name | Ticker | Weight % ▼ | Mkt Value | Shares | P/E | Mkt Cap | Sector |
|---|---|---|---|---|---|---|---|---|
| 1 | Eli Lilly & Co. | LLY | 8.31% | $379.9M | 497,962 | 38.6 | $847.1B | Healthcare |
| 2 | Johnson & Johnson | JNJ | 5.01% | $229.2M | 1,235,890 | 22.0 | $576.5B | Healthcare |
| 3 | AstraZeneca PLC | ZEG.DE | 4.22% | $143.6M | 1,264,267 | 28.7 | $249.2B | Healthcare |
| 4 | UnitedHealth Group Inc. | UNH.BA | 4.21% | $192.3M | 556,891 | 19.8 | $351.1T | Healthcare |
| 5 | AbbVie Inc. | ABBV | 3.58% | $163.6M | 706,535 | 89.5 | $373.3B | Healthcare |
| 6 | Abbott Laboratories | ABT.SW | 3.16% | $144.6M | 1,079,904 | 27.9 | $146.8B | Healthcare |
| 7 | Argenx SE | ARGX | 2.82% | $129.2M | 175,105 | 38.0 | $42.9B | Healthcare |
| 8 | Boston Scientific Corporation | BSX | 2.74% | $125.5M | 1,285,401 | 35.6 | $104.1B | Healthcare |
| 9 | Sanofi SA | SNYNF | 2.69% | $104.7M | 1,300,755 | 9.5 | $110.3B | Healthcare |
| 10 | Novartis AG | NVS | 2.56% | $117.3M | 914,366 | 20.4 | $289.4B | Healthcare |
| 11 | Thermo Fisher Scientific Inc | TMO | 2.30% | $105.0M | 216,413 | 26.7 | $181.6B | Healthcare |
| 12 | Amgen Inc. | AMGN | 2.24% | $102.2M | 362,293 | 24.7 | $190.4B | Healthcare |
| 13 | Intuitive Surgical Inc. | ISRG | 2.14% | $98.1M | 219,297 | 56.6 | $166.4B | Healthcare |
| 14 | HCA Healthcare Inc | HCA | 2.13% | $97.3M | 228,288 | 16.2 | $107.4B | Healthcare |
| 15 | Vertex Pharmaceuticals Incorporated | VRTX | 2.09% | $95.5M | 243,863 | 28.7 | $115.2B | Healthcare |
| 16 | Danaher Corporation | DHR | 1.84% | $84.2M | 424,559 | 35.8 | $133.0B | Healthcare |
| 17 | Stryker Corporation | SYK | 1.83% | $83.5M | 225,946 | 38.7 | $127.3B | Healthcare |
| 18 | Bridgebio Pharma Inc | BBIO | 1.71% | $78.1M | 1,502,856 | -19.2 | $14.1B | Healthcare |
| 19 | Roche Holding AG | ROG.SW | 1.70% | $61.7M | 235,574 | 19.3 | $256.6B | Healthcare |
| 20 | Ascendis Pharma A/S | ASND | 1.66% | $76.0M | 382,422 | -51.6 | $13.5B | Healthcare |
| 21 | Medtronic PLC | MDT | 1.66% | $75.8M | 795,435 | 24.1 | $112.6B | Healthcare |
| 22 | CVS Health Corp | CVS | 1.65% | $75.2M | 998,078 | 51.0 | $90.6B | Healthcare |
| 23 | Avidity Biosciences Inc. | RNAM | 1.58% | $72.2M | 1,656,561 | — | $11.3B | Healthcare |
| 24 | Madrigal Pharmaceuticals Inc | MDGL | 1.50% | $68.6M | 149,654 | -40.4 | $11.9B | Healthcare |
| 25 | Soleno Therapeutics Inc | SLNO | 1.50% | $68.6M | 1,015,340 | 76.4 | $1.7B | Healthcare |
| 26 | Mckesson Corp. | MCK | 1.44% | $65.9M | 85,319 | 24.4 | $106.6B | Healthcare |
| 27 | Revolution Medicines Inc | RVMDW | 1.35% | $61.7M | 1,321,139 | -15.9 | $327M | Healthcare |
| 28 | Akero Therapeutics Inc | AKRO | 1.34% | $61.2M | 1,289,433 | -15.3 | $4.5B | Healthcare |
| 29 | Gilead Sciences Inc. | GILD.SW | 1.15% | $52.7M | 475,138 | — | $142.5B | Healthcare |
| 30 | Cencora Inc | ABC | 1.12% | $51.4M | 164,570 | 37.5 | $36.1B | Healthcare |
| 31 | Mirum Pharmaceuticals Inc. | MIRM | 1.05% | $48.0M | 654,790 | -192.0 | $4.5B | Healthcare |
| 32 | DexCom Inc | DXCM | 0.96% | $44.1M | 654,827 | 29.4 | $25.8B | Healthcare |
| 33 | PTC Therapeutics, Inc. | PTCT | 0.96% | $43.7M | 712,301 | 7.9 | $5.5B | Healthcare |
| 34 | Globus Med Inc | GMED | 0.94% | $42.9M | 748,396 | 20.9 | $11.7B | Healthcare |
| 35 | Teva Pharmaceutical Industries Ltd. | TEVA | 0.92% | $42.0M | 2,078,509 | 23.7 | $34.7B | Healthcare |
| 36 | Travere Therapeutics Inc | TVTX | 0.84% | $38.6M | 1,616,705 | -49.2 | $2.6B | Healthcare |
| 37 | Daiichi Sankyo Co Ltd. | 4568.T | 0.84% | $5.7B | 1,708,900 | 17.8 | $5.3T | Healthcare |
| 38 | Dyne Therapeutics Inc. | DYN | 0.79% | $36.2M | 2,858,143 | -5.2 | $3.1B | Healthcare |
| 39 | Edwards Lifesciences Corporation | EW | 0.79% | $36.0M | 463,525 | 43.4 | $47.7B | Healthcare |
| 40 | Vaxcyte Inc | PCVX | 0.79% | $35.9M | 998,056 | -9.5 | $7.9B | Healthcare |
| 41 | The Cooper Companies, Inc. | 0I3I.L | 0.71% | $32.6M | 475,586 | 34.6 | $14.3B | Healthcare |
| 42 | Elevance Health Inc. | ANTM | 0.70% | $32.2M | 99,500 | 11.4 | $114.6B | Healthcare |
| 43 | Becton, Dickinson and Company | BDX | 0.69% | $31.4M | 167,825 | 25.4 | $57.0B | Healthcare |
| 44 | Metsera Inc. | MTSR | 0.67% | $30.7M | 585,969 | -23.6 | $7.4B | Healthcare |
| 45 | JANUS CAPITAL GROUP INC Private | — | 0.66% | $30.1M | 30,056,283 | — | — | — |
| 46 | Lantheus Holdings Inc | LNTH | 0.61% | $27.9M | 544,082 | 21.1 | $5.1B | Healthcare |
| 47 | Nuvalent Inc | NUVL | 0.57% | $26.2M | 302,812 | -17.2 | $7.2B | Healthcare |
| 48 | Penumbra Inc. | PEN | 0.52% | $23.8M | 93,774 | 73.9 | $13.2B | Healthcare |
| 49 | Avadel Pharmaceuticals PLC | AVDL | 0.50% | $23.0M | 1,503,297 | -7558.7 | $2.1B | Healthcare |
| 50 | HeartFlow Inc Private | — | 0.49% | $22.3M | 662,334 | — | — | — |