RYOIX
Rydex Biotechnology Inv
1W: -2.3%
1M: -4.2%
3M: +1.2%
YTD: +24.0%
1Y: +24.4%
3Y: +40.6%
5Y: +8.6%
$93.21
+0.07 (+0.08%)
Weekly Expected Move ±2.6%
$88
$91
$93
$96
$98
ETF-Level Metrics
AUM$98M
Holdings70
Top 10 Wt36.7%
Beta0.68
% Profitable43%
Coverage92%
Portfolio Valuation
P/E38.9
P/B8.4
P/S5.2
EV/EBITDA21.6
P/FCF19.4
PEG3.38
Profitability & Returns
Gross Margin82.0%
Net Margin6.2%
ROE10.4%
ROA2.7%
ROIC17.3%
Div Yield0.49%
Leverage & Liquidity
Debt/Equity1.49
Debt/Assets0.40
Net Debt/EBITDA1.7x
Interest Cov7.2x
Current Ratio1.28
Quick Ratio1.07
Growth (YoY)
Revenue+31.3%
Net Income+26.9%
EPS+30.7%
FCF+25.4%
EBITDA+33.5%
Rev CAGR 3Y+40.6%
Quality Scores
Piotroski F5.0
Altman Z11.38
IS Quality60.9
IS Overall53.1
IS Value39.7
Median P/E-6.5
Sector Breakdown
3 sectors| Sector | # Holdings | Total Weight % | Avg P/E |
|---|---|---|---|
| Healthcare | 69 | 97.2% | -17.7 |
| Other | 5 | 1.5% | — |
| Financial Services | 1 | 0.5% | 10.4 |
Smart Money Overlap
0 holdings with signalsNo holdings with active convergence signals
Showing 50 of 75 holdings
· Page 1 of 2
| # | Name | Ticker | Weight % ▼ | Mkt Value | Shares | P/E | Mkt Cap | Sector |
|---|---|---|---|---|---|---|---|---|
| 1 | AbbVie Inc. | 4AB.DE | 7.39% | $10.0M | 45,923 | 74.0 | $408.1B | Healthcare |
| 2 | Amgen Inc. | 4332.HK | 5.23% | $7.1M | 20,093 | — | $998.5B | Healthcare |
| 3 | Gilead Sciences Inc. | GILD.SW | 4.96% | $6.7M | 48,042 | -55.7 | $143.2B | Healthcare |
| 4 | Vertex Pharmaceuticals Incorporated | VX1.DE | 4.01% | $5.4M | 12,119 | 29.1 | $113.3B | Healthcare |
| 5 | Regeneron Pharmaceuticals, Inc. | 0R2M.L | 3.56% | $4.8M | 6,224 | 17.6 | $79.6B | Healthcare |
| 6 | Alnylam Pharmaceuticals Inc. | 0HD2.L | 2.60% | $3.5M | 10,632 | 36.0 | $29.7B | Healthcare |
| 7 | Insmed Inc | 0JAV.L | 2.45% | $3.3M | 20,277 | -27.0 | $23.7B | Healthcare |
| 8 | BEONE MEDICINES LTD | BGNE | 2.29% | $3.1M | 10,395 | 3.6 | $20.2B | Healthcare |
| 9 | NATERA INC | NTRA | 2.09% | $2.8M | 14,145 | -301.7 | $58.8B | Healthcare |
| 10 | United Therapeutics Corporation | UTHR | 2.07% | $2.8M | 4,711 | 17.9 | $23.0B | Healthcare |
| 11 | Biogen Inc | BIIB.SW | 2.01% | $2.7M | 14,803 | 30.0 | $20.8B | Healthcare |
| 12 | Royalty Pharma PLC | RPRX | 1.98% | $2.7M | 55,739 | 23.7 | $25.3B | Healthcare |
| 13 | Illumina Inc | ILU.DE | 1.74% | $2.3M | 19,053 | 25.9 | $18.8B | Healthcare |
| 14 | Revolution Medicines Inc | RVMD | 1.69% | $2.3M | 23,475 | -23.3 | $43.9B | Healthcare |
| 15 | Moderna Inc | 0QF.F | 1.65% | $2.2M | 43,818 | -23.8 | $66.4B | Healthcare |
| 16 | AstraZeneca PLC | ZEG.DE | 1.60% | $2.2M | 10,974 | 23.4 | $249.2B | Healthcare |
| 17 | Argenx SE | ARGNF | 1.60% | $2.2M | 2,961 | 33.3 | $58.2B | Healthcare |
| 18 | Incyte Corporation. | 0J9P.L | 1.56% | $2.1M | 22,317 | 14.2 | $22.8B | Healthcare |
| 19 | Viatris Inc | VTRS | 1.50% | $2.0M | 150,073 | -48.9 | $20.5B | Healthcare |
| 20 | Bridgebio Pharma Inc | BBIO | 1.47% | $2.0M | 26,764 | -18.8 | $13.2B | Healthcare |
| 21 | Alkermes PLC | ALKS | 1.47% | $2.0M | 56,068 | 103.6 | $7.0B | Healthcare |
| 22 | Jazz Pharmaceuticals PLC | JAZZ | 1.46% | $2.0M | 10,448 | 15.5 | $14.8B | Healthcare |
| 23 | Neurocrine Biosciences Inc | 0K6R.L | 1.42% | $1.9M | 14,527 | 20.3 | $14.3B | Healthcare |
| 24 | Guardant Health Inc | GH | 1.41% | $1.9M | 20,606 | -50.9 | $23.9B | Healthcare |
| 25 | Roivant Sciences Ltd | ROIVW | 1.40% | $1.9M | 68,372 | -4.3 | $2.0B | Healthcare |
| 26 | Ionis Pharmaceuticals, Inc. | 0JDI.L | 1.38% | $1.9M | 24,870 | -12.6 | $7.1B | Healthcare |
| 27 | Exelixis, Inc. | EX9.DE | 1.29% | $1.7M | 40,607 | 17.7 | $9.2B | Healthcare |
| 28 | Medpace Holdings Inc. | MEDP | 1.26% | $1.7M | 3,540 | 34.5 | $16.7B | Healthcare |
| 29 | Biomarin Pharmaceutical Inc. | BM8.DE | 1.24% | $1.7M | 29,738 | 50.9 | $11.8B | Healthcare |
| 30 | Apellis Pharmaceuticals Inc | APLS | 1.22% | $1.7M | 41,107 | 38.7 | $5.3B | Healthcare |
| 31 | Arrowhead Pharmaceuticals Inc | 0HI3.L | 1.22% | $1.7M | 26,370 | -28.7 | $9.0B | Healthcare |
| 32 | Cytokinetics Inc | CYTK | 1.18% | $1.6M | 24,093 | -9.1 | $8.2B | Healthcare |
| 33 | Vaxcyte Inc | PCVX | 1.14% | $1.5M | 26,383 | -7.4 | $8.2B | Healthcare |
| 34 | CRISPR Therapeutics AG | CRSP | 1.13% | $1.5M | 32,054 | -11.6 | $5.3B | Healthcare |
| 35 | Halozyme Therapeutics Inc | 0J2O.L | 1.09% | $1.5M | 22,712 | 31.2 | $13.0B | Healthcare |
| 36 | BioNTech SE | 22UA.F | 1.06% | $1.4M | 16,159 | -12.7 | $21.5B | Healthcare |
| 37 | Axsome Therapeutics Inc. | 0HKF.L | 1.02% | $1.4M | 8,171 | -47.8 | $8.8B | Healthcare |
| 38 | Ascendis Pharma A/S Private | — | 1.01% | $1.4M | 5,974 | — | — | — |
| 39 | COGENT BIOSCIENCES INC | COGT | 0.99% | $1.3M | 34,752 | -13.4 | $5.3B | Healthcare |
| 40 | Arcellx Inc | ACLX | 0.99% | $1.3M | 11,645 | -28.3 | $6.7B | Healthcare |
| 41 | TG Therapeutics Inc | 0VGI.L | 0.96% | $1.3M | 39,225 | 17.8 | $8.1B | Healthcare |
| 42 | PTC Therapeutics, Inc. | PTCT | 0.96% | $1.3M | 18,935 | -129.5 | $5.3B | Healthcare |
| 43 | Scholar Rock Holding Corp. | SRRK | 0.94% | $1.3M | 25,883 | -14.1 | $5.6B | Healthcare |
| 44 | Madrigal Pharmaceuticals Inc | MDGL | 0.90% | $1.2M | 2,329 | -38.7 | $11.5B | Healthcare |
| 45 | Mirum Pharmaceuticals Inc. | MIRM | 0.89% | $1.2M | 13,080 | -5.7 | $5.1B | Healthcare |
| 46 | Protagonist Therapeutics Inc | PTGX | 0.87% | $1.2M | 11,198 | 115.0 | $9.0B | Healthcare |
| 47 | Amicus Therapeutics Inc. | FOLD | 0.82% | $1.1M | 76,280 | -783.2 | $4.5B | Healthcare |
| 48 | Rhythm Pharmaceuticals Inc | RYTM | 0.78% | $1.1M | 12,158 | -29.8 | $6.4B | Healthcare |
| 49 | APOGEE THERAPEUTICS INC | APGE | 0.75% | $1.0M | 12,066 | -31.1 | $8.4B | Healthcare |
| 50 | Kymera Therapeutics Inc | KYMR | 0.72% | $970,995 | 11,658 | -33.0 | $8.8B | Healthcare |