Asset Manager
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RA CAPITAL MANAGEMENT, L.P.
Market Value
$11.0B
+67.5%
Holdings
98
+8
New Purchases
17
Added To
10
Closed
17
Reduced
10
Top 10 Concentration
62.1%
Turnover
34.7%
Top Buys (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| ASND | 24.88% | 0.00% | +24.88% | $2.7B |
| PBLS | 7.19% | 0.00% | +7.19% | $792M |
| COAG | 2.60% | 0.00% | +2.60% | $287M |
| ABVX | 1.37% | 0.00% | +1.37% | $151M |
| ORKA | 1.34% | 0.00% | +1.34% | $148M |
| NTLA | 0.70% | 0.00% | +0.70% | $77M |
| DFTX | 0.64% | 0.00% | +0.64% | $71M |
| ARTV | 1.58% | 0.96% | +0.62% | $174M |
| SANA | 0.59% | 0.00% | +0.59% | $65M |
| PRLD | 0.31% | 0.00% | +0.31% | $35M |
| QTTB | 0.27% | 0.00% | +0.27% | $30M |
| EDIT | 0.26% | 0.00% | +0.26% | $29M |
| ACRS | 0.61% | 0.39% | +0.22% | $67M |
| GHRS | 1.86% | 1.64% | +0.22% | $205M |
| ALT | 0.18% | 0.00% | +0.18% | $20M |
Top Sells (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| PCVX | 6.05% | 10.14% | -4.08% | $667M |
| TYRA | 3.54% | 7.10% | -3.57% | $390M |
| DNTH | 0.00% | 3.33% | -3.33% | $0 |
| NUVL | 1.40% | 3.95% | -2.55% | $154M |
| RYTM | 6.72% | 8.81% | -2.10% | $740M |
| SION | 3.95% | 6.04% | -2.08% | $436M |
| EWTX | 3.09% | 4.99% | -1.90% | $341M |
| PRAX | 0.00% | 1.83% | -1.83% | $0 |
| SGP | 1.62% | 3.16% | -1.54% | $179M |
| SRPT | 0.00% | 1.29% | -1.29% | $0 |
| MLYS | 1.88% | 3.17% | -1.28% | $208M |
| SYRE | 0.00% | 1.24% | -1.24% | $0 |
| VOR | 0.40% | 1.47% | -1.06% | $44M |
| GERN | 0.50% | 1.44% | -0.95% | $55M |
| BCRX | 1.44% | 2.29% | -0.85% | $158M |
Sector Allocation Over Time
Market Cap Concentration
| Tier | Holdings | Value | Weight |
|---|---|---|---|
| Large Cap | 1 | $2.7B | 24.9% |
| Mid Cap | 22 | $3.8B | 34.2% |
| Small Cap | 44 | $3.5B | 31.4% |
| Micro Cap | 31 | $1.0B | 9.5% |
Portfolio Analytics
Avg Market Cap
$1.7B
Median Market Cap
$652M
Avg P/E
26.2
Median P/E
16.7
Avg Dividend Yield
—%
Avg Beta
1.03
# Stocks
98
# ETFs / Funds
0
Top Holdings (98 total)
| # | Symbol | % Port | Shares | Value | Avg Price | Q/Q Value Chg | Share Chg | Chg % | Status |
|---|---|---|---|---|---|---|---|---|---|
| 1 | ASND | 24.88% | 10,281,496 | $2.7B | $266.72 | — | +10,281,496 | — | NEW |
| 2 | PBLS | 7.19% | 28,933,371 | $792M | $27.37 | — | +28,933,371 | — | NEW |
| 3 | RYTM | 6.72% | 6,666,837 | $740M | $111.03 | $160M | — | — | |
| 4 | PCVX | 6.05% | 11,474,599 | $667M | $58.13 | $229K | — | — | |
| 5 | SION | 3.95% | 9,905,045 | $436M | $43.99 | $39M | — | — | |
| 6 | TYRA | 3.54% | 12,198,625 | $390M | $31.94 | -$78M | — | — | |
| 7 | EWTX | 3.09% | 8,392,730 | $341M | $40.63 | $13M | -2,035,707 | -19.5% | |
| 8 | COAG | 2.60% | 7,808,627 | $287M | $36.73 | — | +7,808,627 | — | NEW |
| 9 | SEPN | 2.13% | 6,995,858 | $234M | $33.49 | $66M | — | — | |
| 10 | BCAX | 1.95% | 7,255,993 | $215M | $29.69 | $71M | — | — | |
| 11 | MLYS | 1.88% | 7,692,750 | $208M | $26.98 | -$846K | — | — | |
| 12 | GHRS | 1.86% | 7,636,813 | $205M | $26.88 | $97M | -39,884 | -0.5% | |
| 13 | IRON | 1.63% | 2,450,221 | $179M | $73.14 | $23M | — | — | |
| 14 | SGP | 1.62% | 8,021,117 | $179M | $22.26 | -$29M | — | — | |
| 15 | ARTV | 1.58% | 17,955,642 | $174M | $9.70 | $111M | +8,102,340 | +82.2% | |
| 16 | JANX | 1.56% | 11,189,693 | $172M | $15.36 | $16M | — | — | |
| 17 | TSHA | 1.46% | 23,555,648 | $160M | $6.81 | $55M | — | — | |
| 18 | BCRX | 1.44% | 15,827,186 | $158M | $10.00 | $8M | — | — | |
| 19 | NUVL | 1.40% | 1,246,456 | $154M | $123.50 | -$106M | -1,287,689 | -50.8% | |
| 20 | ABVX | 1.37% | 1,132,557 | $151M | $133.26 | — | +1,132,557 | — | NEW |
| 21 | ORKA | 1.34% | 1,554,597 | $148M | $95.17 | — | +1,554,597 | — | NEW |
| 22 | CLYM | 1.34% | 11,300,939 | $147M | $13.04 | $70M | — | — | |
| 23 | SLDB | 1.09% | 12,036,126 | $120M | $9.99 | $53M | +2,696,148 | +28.9% | |
| 24 | ZLAB | 0.99% | 5,743,533 | $109M | $19.00 | $2M | +36,271 | +0.6% | |
| 25 | SBTX | 0.79% | 10,860,977 | $87M | $8.01 | -$217K | — | — | |
| 26 | XNCR | 0.77% | 5,274,274 | $85M | $16.10 | $26M | +377,037 | +7.7% | |
| 27 | JBIO | 0.74% | 3,671,083 | $82M | $22.22 | $30M | — | — | |
| 28 | NTLA | 0.70% | 4,526,926 | $77M | $16.92 | — | +4,526,926 | — | NEW |
| 29 | LBRX | 0.65% | 2,208,604 | $72M | $32.46 | $17M | — | — | |
| 30 | DFTX | 0.64% | 1,500,000 | $71M | $47.04 | — | +1,500,000 | — | NEW |
| 31 | ACRS | 0.61% | 12,723,026 | $67M | $5.29 | $42M | +5,918,954 | +87.0% | |
| 32 | FDMT | 0.61% | 5,049,779 | $67M | $13.30 | $20M | — | — | |
| 33 | SANA | 0.59% | 18,750,000 | $65M | $3.49 | — | +18,750,000 | — | NEW |
| 34 | GLTO | 0.57% | 2,399,702 | $62M | $26.01 | $274K | +392 | +0.0% | |
| 35 | MNPR | 0.56% | 667,207 | $62M | $92.59 | $25M | — | — | |
| 36 | ABOS | 0.51% | 20,992,669 | $56M | $2.67 | $7M | — | — | |
| 37 | GERN | 0.50% | 42,809,751 | $55M | $1.28 | -$40M | -20,961,615 | -32.9% | |
| 38 | RZLT | 0.45% | 9,445,039 | $49M | $5.20 | $21M | +265,039 | +2.9% | |
| 39 | EVMN | 0.42% | 3,494,638 | $46M | $13.29 | -$34M | — | — | |
| 40 | VOR | 0.40% | 2,402,095 | $44M | $18.41 | -$52M | -3,002,903 | -55.6% | |
| 41 | IPSC | 0.39% | 17,754,430 | $43M | $2.45 | $3M | — | — | |
| 42 | AKTS | 0.38% | 1,314,405 | $42M | $32.23 | $15M | -188,679 | -12.6% | |
| 43 | BIOA | 0.37% | 1,671,648 | $41M | $24.51 | $12M | +21,000 | +1.3% | |
| 44 | CCCC | 0.34% | 8,000,000 | $37M | $4.67 | $16M | — | — | |
| 45 | MIRM | 0.34% | 318,554 | $37M | $117.07 | $8M | — | — | |
| 46 | CAPR | 0.33% | 1,507,844 | $36M | $24.08 | -$10M | — | — | |
| 47 | PEPG | 0.33% | 20,064,545 | $36M | $1.80 | $602K | — | — | |
| 48 | PRLD | 0.31% | 6,475,882 | $35M | $5.33 | — | +6,475,882 | — | NEW |
| 49 | NKTX | 0.28% | 10,805,129 | $31M | $2.83 | $8M | — | — | |
| 50 | QTTB | 0.27% | 2,332,457 | $30M | $12.74 | — | +2,332,457 | — | NEW |
| 51 | AVR | 0.27% | 3,000,000 | $30M | $9.85 | $13M | — | — | |
| 52 | EDIT | 0.26% | 8,889,000 | $29M | $3.24 | — | +8,889,000 | — | NEW |
| 53 | OVID | 0.26% | 10,500,968 | $28M | $2.69 | $4M | -213,032 | -2.0% | |
| 54 | ASMB | 0.25% | 1,020,410 | $28M | $27.48 | -$276K | — | — | |
| 55 | ALXO | 0.24% | 13,011,849 | $27M | $2.07 | $846K | — | — | |
| 56 | BNTC | 0.22% | 1,850,000 | $25M | $13.38 | $5M | — | — | |
| 57 | LENZ | 0.22% | 4,178,823 | $24M | $5.68 | -$15M | — | — | |
| 58 | LXEO | 0.21% | 5,000,000 | $23M | $4.66 | -$5M | — | — | |
| 59 | ACRV | 0.20% | 12,229,396 | $22M | $1.78 | $10M | +3,888,888 | +46.6% | |
| 60 | ALT | 0.18% | 6,500,000 | $20M | $3.04 | — | +6,500,000 | — | NEW |
| 61 | KPTI | 0.17% | 1,917,354 | $19M | $9.77 | $8M | — | — | |
| 62 | DRUG | 0.17% | 265,000 | $19M | $70.20 | -$734K | — | — | |
| 63 | AVTX | 0.17% | 1,000,000 | $18M | $18.48 | $9M | +337,032 | +50.8% | |
| 64 | OKUR | 0.17% | 3,998,333 | $18M | $4.56 | $2M | — | — | |
| 65 | FTH | 0.16% | 722,020 | $18M | $25.00 | — | +722,020 | — | NEW |
| 66 | AURA | 0.16% | 2,500,000 | $18M | $7.10 | — | +2,500,000 | — | NEW |
| 67 | SABS | 0.16% | 4,401,500 | $17M | $3.90 | $308K | — | — | |
| 68 | SPTX | 0.14% | 700,000 | $15M | $21.72 | — | +700,000 | — | NEW |
| 69 | PALI | 0.14% | 7,124,116 | $15M | $2.09 | $2M | — | — | |
| 70 | HLXC | 0.12% | 1,250,000 | $13M | $10.64 | $600K | — | — | |
| 71 | WAY | 0.10% | 529,400 | $11M | $20.53 | -$2M | — | — | |
| 72 | EQ | 0.09% | 3,096,336 | $10M | $3.20 | $4M | — | — | |
| 73 | MGNX | 0.08% | 1,864,176 | $9M | $4.62 | $3M | — | — | |
| 74 | PCSC | 0.07% | 750,000 | $8M | $10.88 | -$68K | — | — | |
| 75 | ACET | 0.07% | 932,624 | $8M | $8.64 | $4K | -250,000 | -21.1% | |
| 76 | CRVS | 0.06% | 450,000 | $7M | $14.94 | $140K | — | — | |
| 77 | RANI | 0.06% | 8,500,000 | $6M | $0.76 | $218K | — | — | |
| 78 | JATT | 0.05% | 500,000 | $6M | $11.36 | — | +500,000 | — | NEW |
| 79 | AMAN | 0.03% | 375,000 | $4M | $10.16 | — | +375,000 | — | NEW |
| 80 | HOWL | 0.01% | 2,387,744 | $859K | $0.36 | -$5M | -4,293,563 | -64.3% | |
| 81 | PTN | 0.01% | 62,124 | $670K | $10.79 | -$549K | -7,876 | -11.2% | |
| 82 | DNTH | —% | — | — | — | -$219M | -2,611,733 | -100.0% | SOLD |
| 83 | STRO | —% | — | — | — | -$18M | -715,307 | -100.0% | SOLD |
| 84 | TVTX | —% | — | — | — | -$22M | -746,841 | -100.0% | SOLD |
| 85 | OLMA | —% | — | — | — | -$39M | -2,600,000 | -100.0% | SOLD |
| 86 | INSP | —% | — | — | — | -$17M | -325,663 | -100.0% | SOLD |
| 87 | CTNM | —% | — | — | — | -$17M | -1,296,012 | -100.0% | SOLD |
| 88 | WGS | —% | — | — | — | -$13M | -209,887 | -100.0% | SOLD |
| 89 | SYRE | —% | — | — | — | -$82M | -1,621,620 | -100.0% | SOLD |
| 90 | HNGE | —% | — | — | — | -$14M | -364,613 | -100.0% | SOLD |
| 91 | FULC | —% | — | — | — | -$46M | -6,053,960 | -100.0% | SOLD |
| 92 | RLMD | —% | — | — | — | -$21M | -2,947,369 | -100.0% | SOLD |
| 93 | RNA | —% | — | — | — | -$12M | -864,102 | -100.0% | SOLD |
| 94 | SRPT | —% | — | — | — | -$85M | -3,902,596 | -100.0% | SOLD |
| 95 | DSGN | —% | — | — | — | -$32M | -2,972,973 | -100.0% | SOLD |
| 96 | PRAX | —% | — | — | — | -$120M | -373,787 | -100.0% | SOLD |
| 97 | MPLT | —% | — | — | — | -$5M | -248,294 | -100.0% | SOLD |
| 98 | GRAL | —% | — | — | — | -$22M | -428,266 | -100.0% | SOLD |