Asset Manager
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Opaleye Management Inc.
Market Value
$696M
+45.1%
Holdings
49
+4
New Purchases
11
Added To
9
Closed
8
Reduced
10
Top 10 Concentration
74.2%
Turnover
38.8%
Top Buys (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| HROW | 27.05% | 24.88% | +2.17% | $188M |
| LQDA | 8.55% | 6.43% | +2.12% | $59M |
| APGE | 2.08% | 0.00% | +2.08% | $14M |
| ALKS | 1.94% | 0.00% | +1.94% | $14M |
| ANNX | 1.14% | 0.00% | +1.14% | $8M |
| STOK | 2.30% | 1.33% | +0.97% | $16M |
| CGON | 2.37% | 1.44% | +0.93% | $17M |
| SLGL | 0.86% | 0.00% | +0.86% | $6M |
| DERM | 0.99% | 0.14% | +0.85% | $7M |
| PLX | 0.82% | 0.00% | +0.82% | $6M |
| TMCI | 0.68% | 0.00% | +0.68% | $5M |
| RYTM | 6.70% | 6.26% | +0.44% | $47M |
| ETON | 8.94% | 8.50% | +0.43% | $62M |
| ADCT | 0.39% | 0.00% | +0.39% | $3M |
| RZLT | 1.22% | 0.84% | +0.38% | $8M |
Top Sells (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| CDXS | 4.49% | 6.41% | -1.93% | $31M |
| VIGL | 0.00% | 1.66% | -1.66% | $0 |
| IMNM | 5.36% | 6.85% | -1.49% | $37M |
| SNWV | 5.28% | 6.72% | -1.44% | $37M |
| ARVN | 1.21% | 2.58% | -1.37% | $8M |
| ANIK | 0.00% | 1.30% | -1.30% | $0 |
| TGTX | 2.78% | 4.02% | -1.24% | $19M |
| DNA | 0.00% | 1.17% | -1.17% | $0 |
| LRMR | 1.52% | 2.48% | -0.96% | $11M |
| EPIX | 0.00% | 0.78% | -0.78% | $0 |
| CRGX | 0.00% | 0.57% | -0.57% | $0 |
| TARA | 0.00% | 0.54% | -0.54% | $0 |
| RCEL | 0.00% | 0.43% | -0.43% | $0 |
| OCUL | 2.68% | 3.09% | -0.41% | $19M |
| ZNTL | 0.07% | 0.47% | -0.40% | $478K |
Sector Allocation Over Time
Market Cap Concentration
| Tier | Holdings | Value | Weight |
|---|---|---|---|
| Large Cap | 1 | $5M | 0.7% |
| Mid Cap | 11 | $203M | 29.2% |
| Small Cap | 20 | $391M | 56.3% |
| Micro Cap | 17 | $96M | 13.8% |
Portfolio Analytics
Avg Market Cap
$2.7B
Median Market Cap
$504M
Avg P/E
45.4
Median P/E
21.3
Avg Dividend Yield
—%
Avg Beta
1.22
# Stocks
49
# ETFs / Funds
0
Top Holdings (49 total)
| # | Symbol | % Port | Shares | Value | Avg Price | Q/Q Value Chg | Share Chg | Chg % | Status |
|---|---|---|---|---|---|---|---|---|---|
| 1 | HROW | 27.05% | 3,905,000 | $188M | $48.18 | $69M | — | — | |
| 2 | ETON | 8.94% | 2,860,000 | $62M | $21.73 | $21M | — | — | |
| 3 | LQDA | 8.55% | 2,615,000 | $59M | $22.74 | $29M | +140,000 | +5.7% | |
| 4 | RYTM | 6.70% | 461,700 | $47M | $100.99 | $17M | -13,300 | -2.8% | |
| 5 | IMNM | 5.36% | 3,185,000 | $37M | $11.71 | $4M | -344,581 | -9.8% | |
| 6 | SNWV | 5.28% | 980,000 | $37M | $37.48 | $5M | — | — | |
| 7 | CDXS | 4.49% | 12,795,000 | $31M | $2.44 | $476K | +195,000 | +1.6% | |
| 8 | TGTX | 2.78% | 535,000 | $19M | $36.13 | $72K | — | — | |
| 9 | OCUL | 2.68% | 1,595,000 | $19M | $11.69 | $4M | — | — | |
| 10 | CGON | 2.37% | 410,000 | $17M | $40.28 | $10M | +144,000 | +54.1% | |
| 11 | STOK | 2.30% | 682,017 | $16M | $23.50 | $10M | +119,897 | +21.3% | |
| 12 | APGE | 2.08% | 363,257 | $14M | $39.73 | — | +363,257 | — | NEW |
| 13 | ALKS | 1.94% | 450,000 | $14M | $30.00 | — | +450,000 | — | NEW |
| 14 | IRON | 1.84% | 193,773 | $13M | $66.08 | $3M | +7,355 | +4.0% | |
| 15 | SRPT | 1.62% | 585,000 | $11M | $19.27 | $3M | +85,000 | +17.0% | |
| 16 | LRMR | 1.52% | 3,720,867 | $11M | $2.84 | -$1M | -389,133 | -9.5% | |
| 17 | XOMA | 1.41% | 255,087 | $10M | $38.54 | $3M | — | — | |
| 18 | RZLT | 1.22% | 903,442 | $8M | $9.40 | $4M | — | — | |
| 19 | ARVN | 1.21% | 987,818 | $8M | $8.52 | -$4M | -692,182 | -41.2% | |
| 20 | EWTX | 1.17% | 500,000 | $8M | $16.22 | $2M | +10,000 | +2.0% | |
| 21 | ANNX | 1.14% | 2,600,000 | $8M | $3.05 | — | +2,600,000 | — | NEW |
| 22 | PTGX | 1.00% | 105,000 | $7M | $66.43 | $1M | — | — | |
| 23 | DERM | 0.99% | 971,064 | $7M | $7.12 | $6M | +876,064 | +922.2% | |
| 24 | SLGL | 0.86% | 204,835 | $6M | $29.15 | — | +204,835 | — | NEW |
| 25 | PLX | 0.82% | 2,580,556 | $6M | $2.22 | — | +2,580,556 | — | NEW |
| 26 | TMCI | 0.68% | 702,245 | $5M | $6.71 | — | +702,245 | — | NEW |
| 27 | RVMD | 0.67% | 100,000 | $5M | $46.70 | $807K | -5,000 | -4.8% | |
| 28 | MBX | 0.64% | 253,000 | $4M | $17.50 | $2M | +13,681 | +5.7% | |
| 29 | TRVI | 0.51% | 390,000 | $4M | $9.15 | $1M | — | — | |
| 30 | ADCT | 0.39% | 682,529 | $3M | $4.00 | — | +682,529 | — | NEW |
| 31 | ALMS | 0.38% | 665,000 | $3M | $3.99 | $328K | -110,000 | -14.2% | |
| 32 | CABA | 0.27% | 808,882 | $2M | $2.34 | — | +808,882 | — | NEW |
| 33 | IRD | 0.26% | 1,100,000 | $2M | $1.65 | $666K | -120,000 | -9.8% | |
| 34 | ZYME | 0.25% | 100,000 | $2M | $17.08 | -$928K | -110,000 | -52.4% | |
| 35 | SYRE | 0.16% | 65,000 | $1M | $16.76 | — | +65,000 | — | NEW |
| 36 | RIGL | 0.15% | 37,787 | $1M | $28.33 | — | +37,787 | — | NEW |
| 37 | ACOG | 0.11% | 115,142 | $750K | $6.51 | — | +115,142 | — | NEW |
| 38 | ZNTL | 0.07% | 316,550 | $478K | $1.51 | -$2M | -1,607,750 | -83.5% | |
| 39 | PEPG | 0.05% | 75,000 | $346K | $4.62 | $80K | -165,000 | -68.8% | |
| 40 | IBIO | 0.04% | 375,000 | $310K | $0.83 | $25K | — | — | |
| 41 | ADGM | 0.03% | 110,571 | $215K | $1.94 | $71K | — | — | |
| 42 | CRGX | —% | — | — | — | -$3M | -666,503 | -100.0% | SOLD |
| 43 | ELEV | —% | — | — | — | -$529K | -1,442,061 | -100.0% | SOLD |
| 44 | ANIK | —% | — | — | — | -$6M | -588,797 | -100.0% | SOLD |
| 45 | RCEL | —% | — | — | — | -$2M | -389,519 | -100.0% | SOLD |
| 46 | VIGL | —% | — | — | — | -$8M | -1,000,000 | -100.0% | SOLD |
| 47 | EPIX | —% | — | — | — | -$4M | -2,209,998 | -100.0% | SOLD |
| 48 | TARA | —% | — | — | — | -$3M | -855,000 | -100.0% | SOLD |
| 49 | DNA | —% | — | — | — | -$6M | -500,000 | -100.0% | SOLD |