Asset Manager
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Avoro Capital Advisors LLC
Market Value
$10.8B
+21.7%
Holdings
31
-3
New Purchases
3
Added To
10
Closed
6
Reduced
3
Top 10 Concentration
81.7%
Turnover
29.0%
Top Buys (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| ASND | 12.59% | 0.00% | +12.59% | $1.4B |
| DFTX | 3.12% | 1.06% | +2.06% | $338M |
| KRYS | 9.92% | 8.39% | +1.53% | $1.1B |
| CYTK | 3.93% | 2.47% | +1.46% | $426M |
| RVMD | 3.97% | 2.56% | +1.41% | $430M |
| ARWR | 8.55% | 7.54% | +1.01% | $926M |
| KYMR | 7.92% | 7.00% | +0.92% | $857M |
| COAG | 0.65% | 0.00% | +0.65% | $71M |
| TSHA | 1.50% | 1.09% | +0.41% | $163M |
| ARGX | 8.57% | 8.21% | +0.36% | $928M |
| FTH | 0.33% | 0.00% | +0.33% | $36M |
| GHRS | 0.45% | 0.28% | +0.16% | $48M |
| AVTX | 0.40% | 0.24% | +0.16% | $43M |
| VRDN | 0.42% | 0.33% | +0.09% | $46M |
| SEPN | 0.41% | 0.36% | +0.05% | $45M |
Top Sells (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| APLS | 0.00% | 5.53% | -5.53% | $0 |
| CNTA | 0.00% | 5.10% | -5.10% | $0 |
| UTHR | 13.90% | 17.53% | -3.63% | $1.5B |
| TERN | 0.00% | 3.37% | -3.37% | $0 |
| MDGL | 9.09% | 10.70% | -1.61% | $984M |
| CELC | 3.29% | 4.33% | -1.04% | $356M |
| SLNO | 0.00% | 0.87% | -0.87% | $0 |
| XENE | 3.22% | 3.78% | -0.56% | $349M |
| ALKS | 0.00% | 0.48% | -0.48% | $0 |
| VERA | 2.27% | 2.66% | -0.39% | $246M |
| GPCR | 3.25% | 3.55% | -0.30% | $352M |
| GLTO | 0.91% | 1.10% | -0.19% | $98M |
| MNKD | 0.00% | 0.06% | -0.06% | $0 |
| LXEO | 0.06% | 0.12% | -0.06% | $7M |
| OCUL | 1.14% | 1.17% | -0.04% | $123M |
Sector Allocation Over Time
Market Cap Concentration
| Tier | Holdings | Value | Weight |
|---|---|---|---|
| Large Cap | 5 | $5.2B | 48.1% |
| Mid Cap | 14 | $4.6B | 42.6% |
| Small Cap | 9 | $881M | 8.1% |
| Micro Cap | 3 | $118M | 1.1% |
Portfolio Analytics
Avg Market Cap
$7.8B
Median Market Cap
$3.5B
Avg P/E
39.5
Median P/E
33.3
Avg Dividend Yield
—%
Avg Beta
0.66
# Stocks
31
# ETFs / Funds
0
Top Holdings (31 total)
| # | Symbol | % Port | Shares | Value | Avg Price | Q/Q Value Chg | Share Chg | Chg % | Status |
|---|---|---|---|---|---|---|---|---|---|
| 1 | UTHR | 13.90% | 2,777,777 | $1.5B | $541.83 | -$54M | +147,777 | +5.6% | |
| 2 | ASND | 12.59% | 5,111,111 | $1.4B | $266.72 | — | +5,111,111 | — | NEW |
| 3 | KRYS | 9.92% | 2,888,888 | $1.1B | $371.67 | $327M | — | — | |
| 4 | MDGL | 9.09% | 1,833,333 | $984M | $536.95 | $33M | +15,152 | +0.8% | |
| 5 | ARGX | 8.57% | 1,000,000 | $928M | $927.77 | $198M | — | — | |
| 6 | ARWR | 8.55% | 11,355,555 | $926M | $81.51 | $255M | +655,556 | +6.1% | |
| 7 | KYMR | 7.92% | 7,474,747 | $857M | $114.67 | $235M | — | — | |
| 8 | RVMD | 3.97% | 2,297,000 | $430M | $187.28 | $202M | -47,444 | -2.0% | |
| 9 | CYTK | 3.93% | 4,999,999 | $426M | $85.19 | $206M | +1,666,666 | +50.0% | |
| 10 | CELC | 3.29% | 3,400,000 | $356M | $104.62 | -$30M | +25,000 | +0.7% | |
| 11 | GPCR | 3.25% | 6,555,555 | $352M | $53.67 | $36M | — | — | |
| 12 | XENE | 3.22% | 5,777,777 | $349M | $60.36 | $13M | — | — | |
| 13 | DFTX | 3.12% | 7,188,888 | $338M | $47.04 | $244M | +2,188,888 | +43.8% | |
| 14 | VERA | 2.27% | 5,723,888 | $246M | $42.91 | $9M | -165,000 | -2.8% | |
| 15 | TSHA | 1.50% | 23,888,888 | $163M | $6.81 | $66M | +2,188,888 | +10.1% | |
| 16 | OCUL | 1.14% | 12,540,000 | $123M | $9.82 | $19M | +225,000 | +1.8% | |
| 17 | GLTO | 0.91% | 3,783,000 | $98M | $26.01 | $416K | — | — | |
| 18 | COAG | 0.65% | 1,925,150 | $71M | $36.73 | — | +1,925,150 | — | NEW |
| 19 | GHRS | 0.45% | 1,800,000 | $48M | $26.88 | $23M | — | — | |
| 20 | VRDN | 0.42% | 2,500,000 | $46M | $18.37 | $17M | +1,000,000 | +66.7% | |
| 21 | SEPN | 0.41% | 1,337,500 | $45M | $33.49 | $13M | — | — | |
| 22 | AVTX | 0.40% | 2,333,333 | $43M | $18.48 | $22M | +923,333 | +65.5% | |
| 23 | FTH | 0.33% | 1,444,039 | $36M | $25.00 | — | +1,444,039 | — | NEW |
| 24 | WHWK | 0.12% | 2,849,402 | $13M | $4.58 | $3M | — | — | |
| 25 | LXEO | 0.06% | 1,489,189 | $7M | $4.66 | -$4M | -385,811 | -20.6% | |
| 26 | APLS | —% | — | — | — | -$492M | -12,222,222 | -100.0% | SOLD |
| 27 | SLNO | —% | — | — | — | -$77M | -2,300,000 | -100.0% | SOLD |
| 28 | TERN | —% | — | — | — | -$300M | -5,695,000 | -100.0% | SOLD |
| 29 | ALKS | —% | — | — | — | -$42M | -1,200,000 | -100.0% | SOLD |
| 30 | CNTA | —% | — | — | — | -$454M | -11,430,455 | -100.0% | SOLD |
| 31 | MNKD | —% | — | — | — | -$5M | -2,200,000 | -100.0% | SOLD |
Options Breakdown
2 Calls
$0 Call Value
0 Puts
$0 Put Value