Asset Manager
← All Institutions
Avoro Capital Advisors LLC
Market Value
$8.9B
+37.4%
Holdings
38
+7
New Purchases
10
Added To
8
Closed
8
Reduced
6
Top 10 Concentration
75.3%
Turnover
47.4%
Top Buys (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| CELC | 3.50% | 0.00% | +3.50% | $310M |
| GPCR | 5.14% | 2.24% | +2.90% | $456M |
| XBI | 2.89% | 0.00% | +2.89% | $256M |
| ARWR | 7.95% | 5.82% | +2.13% | $705M |
| TERN | 1.98% | 0.00% | +1.98% | $176M |
| RVMD | 1.95% | 0.00% | +1.95% | $173M |
| UTHR | 14.32% | 13.13% | +1.18% | $1.3B |
| KYMR | 6.56% | 5.57% | +0.99% | $582M |
| PTCT | 0.59% | 0.00% | +0.59% | $52M |
| VERA | 3.36% | 2.80% | +0.57% | $298M |
| VRDN | 0.53% | 0.00% | +0.53% | $47M |
| KRYS | 8.03% | 7.60% | +0.43% | $712M |
| APGE | 0.43% | 0.00% | +0.43% | $38M |
| LXEO | 0.37% | 0.00% | +0.37% | $33M |
| GHRS | 0.26% | 0.00% | +0.26% | $23M |
Top Sells (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| MRUS | 0.00% | 5.17% | -5.17% | $0 |
| AKRO | 0.00% | 2.91% | -2.91% | $0 |
| ARGX | 9.39% | 11.31% | -1.93% | $833M |
| TRML | 0.00% | 1.89% | -1.89% | $0 |
| FOLD | 0.00% | 1.83% | -1.83% | $0 |
| ETNB | 0.00% | 1.45% | -1.45% | $0 |
| SLNO | 1.51% | 2.70% | -1.19% | $134M |
| MDGL | 11.87% | 13.03% | -1.16% | $1.1B |
| APLS | 3.46% | 4.29% | -0.82% | $307M |
| RNAM | 4.44% | 5.16% | -0.72% | $393M |
| XENE | 2.74% | 3.36% | -0.62% | $243M |
| ALKS | 0.44% | 1.04% | -0.60% | $39M |
| OCUL | 1.48% | 1.86% | -0.38% | $131M |
| MLTX | 0.00% | 0.22% | -0.22% | $0 |
| BCRX | 0.00% | 0.15% | -0.15% | $0 |
Sector Allocation Over Time
Market Cap Concentration
| Tier | Holdings | Value | Weight |
|---|---|---|---|
| Large Cap | 6 | $3.7B | 42.1% |
| Mid Cap | 22 | $4.3B | 48.5% |
| Small Cap | 8 | $791M | 8.9% |
| Micro Cap | 2 | $40M | 0.4% |
Portfolio Analytics
Avg Market Cap
$7.8B
Median Market Cap
$4.5B
Avg P/E
39.1
Median P/E
33.0
Avg Dividend Yield
—%
Avg Beta
0.62
# Stocks
37
# ETFs / Funds
1
Top Holdings (38 total)
| # | Symbol | % Port | Shares | Value | Avg Price | Q/Q Value Chg | Share Chg | Chg % | Status |
|---|---|---|---|---|---|---|---|---|---|
| 1 | UTHR | 14.32% | 2,606,060 | $1.3B | $487.25 | $422M | +583,838 | +28.9% | |
| 2 | MDGL | 11.87% | 1,807,500 | $1.1B | $582.34 | $212M | -25,500 | -1.4% | |
| 3 | ARGX | 9.39% | 990,000 | $833M | $840.95 | $102M | — | — | |
| 4 | KRYS | 8.03% | 2,888,888 | $712M | $246.54 | $222M | +111,111 | +4.0% | |
| 5 | ARWR | 7.95% | 10,625,000 | $705M | $66.39 | $329M | -275,000 | -2.5% | |
| 6 | KYMR | 6.56% | 7,474,747 | $582M | $77.81 | $222M | +1,124,747 | +17.7% | |
| 7 | GPCR | 5.14% | 6,555,555 | $456M | $69.55 | $312M | +1,400,000 | +27.2% | |
| 8 | RNAM | 4.44% | 5,455,000 | $393M | $72.13 | $60M | -2,190,000 | -28.6% | |
| 9 | CNTA | 4.10% | 14,555,555 | $364M | $25.01 | $102M | +3,747,475 | +34.7% | |
| 10 | CELC | 3.50% | 3,111,111 | $310M | $99.74 | — | +3,111,111 | — | NEW |
| 11 | APLS | 3.46% | 12,222,222 | $307M | $25.12 | $30M | — | — | |
| 12 | VERA | 3.36% | 5,888,888 | $298M | $50.64 | $118M | -321,112 | -5.2% | |
| 13 | XBI | 2.89% | 2,100,000 | $256M | $121.93 | — | +2,100,000 | — | NEW |
| 14 | XENE | 2.74% | 5,424,444 | $243M | $44.82 | $26M | +24,444 | +0.5% | |
| 15 | TERN | 1.98% | 4,350,000 | $176M | $40.40 | — | +4,350,000 | — | NEW |
| 16 | RVMD | 1.95% | 2,170,000 | $173M | $79.65 | — | +2,170,000 | — | NEW |
| 17 | SLNO | 1.51% | 2,900,000 | $134M | $46.30 | -$40M | +322,223 | +12.5% | |
| 18 | OCUL | 1.48% | 10,777,777 | $131M | $12.14 | $11M | +527,777 | +5.2% | |
| 19 | TSHA | 1.35% | 21,700,000 | $119M | $5.50 | $48M | — | — | |
| 20 | PTCT | 0.59% | 685,000 | $52M | $75.96 | — | +685,000 | — | NEW |
| 21 | VRDN | 0.53% | 1,500,000 | $47M | $31.12 | — | +1,500,000 | — | NEW |
| 22 | ORKA | 0.46% | 1,333,340 | $40M | $30.31 | $15M | — | — | |
| 23 | ALKS | 0.44% | 1,400,000 | $39M | $27.98 | -$28M | -840,000 | -37.5% | |
| 24 | APGE | 0.43% | 500,000 | $38M | $75.48 | — | +500,000 | — | NEW |
| 25 | SEPN | 0.42% | 1,337,500 | $37M | $27.88 | $12M | — | — | |
| 26 | LXEO | 0.37% | 3,300,000 | $33M | $9.93 | — | +3,300,000 | — | NEW |
| 27 | MNKD | 0.28% | 4,444,444 | $25M | $5.67 | $1M | -24,433 | -0.6% | |
| 28 | GHRS | 0.26% | 1,800,000 | $23M | $12.70 | — | +1,800,000 | — | NEW |
| 29 | INCY | 0.15% | 135,000 | $13M | $98.77 | — | +135,000 | — | NEW |
| 30 | WHWK | 0.08% | 2,849,402 | $7M | $2.42 | $1M | — | — | |
| 31 | MRUS | —% | — | — | — | -$334M | -3,542,500 | -100.0% | SOLD |
| 32 | BCRX | —% | — | — | — | -$9M | -1,250,000 | -100.0% | SOLD |
| 33 | MLTX | —% | — | — | — | -$14M | -2,000,000 | -100.0% | SOLD |
| 34 | TRML | —% | — | — | — | -$122M | -2,555,555 | -100.0% | SOLD |
| 35 | AKRO | —% | — | — | — | -$188M | -3,955,555 | -100.0% | SOLD |
| 36 | ETNB | —% | — | — | — | -$94M | -6,387,790 | -100.0% | SOLD |
| 37 | FOLD | —% | — | — | — | -$118M | -15,025,000 | -100.0% | SOLD |
| 38 | TNGX | —% | — | — | — | -$5M | -545,000 | -100.0% | SOLD |
Options Breakdown
2 Calls
$0 Call Value
0 Puts
$0 Put Value