Asset Manager
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Commodore Capital LP
Market Value
$1.4B
-27.0%
Holdings
41
+3
New Purchases
6
Added To
4
Closed
10
Reduced
10
Top 10 Concentration
58.9%
Turnover
39.0%
Top Buys (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| RLAY | 10.11% | 4.55% | +5.56% | $144M |
| TYRA | 6.24% | 2.42% | +3.81% | $89M |
| SYRE | 5.50% | 1.71% | +3.79% | $78M |
| ANRO | 2.28% | 0.00% | +2.28% | $32M |
| ALKS | 6.98% | 4.76% | +2.22% | $99M |
| ORKA | 3.73% | 1.73% | +2.01% | $53M |
| TERN | 4.19% | 2.20% | +1.99% | $60M |
| AMLX | 4.80% | 2.84% | +1.96% | $68M |
| KYMR | 4.10% | 2.18% | +1.92% | $58M |
| PALI | 1.89% | 0.00% | +1.89% | $27M |
| NRIX | 3.03% | 1.79% | +1.24% | $43M |
| LBRX | 2.35% | 1.21% | +1.13% | $33M |
| ASMB | 2.39% | 1.31% | +1.08% | $34M |
| CTMX | 2.30% | 1.26% | +1.04% | $33M |
| PEPG | 1.56% | 0.56% | +1.00% | $22M |
Top Sells (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| MRUS | 0.00% | 17.02% | -17.02% | $0 |
| AGIO | 0.00% | 4.81% | -4.81% | $0 |
| VRDN | 0.00% | 3.54% | -3.54% | $0 |
| CDTX | 0.00% | 2.87% | -2.87% | $0 |
| NUVL | 3.89% | 6.21% | -2.32% | $55M |
| CNTA | 1.76% | 3.54% | -1.79% | $25M |
| DRUG | 0.10% | 1.56% | -1.45% | $1M |
| SLNO | 3.90% | 4.68% | -0.78% | $56M |
| PTGX | 2.76% | 3.49% | -0.73% | $39M |
| TNGX | 0.00% | 0.65% | -0.65% | $0 |
| APGE | 0.00% | 0.59% | -0.59% | $0 |
| ENTA | 0.00% | 0.49% | -0.49% | $0 |
| PCSC | 0.00% | 0.41% | -0.41% | $0 |
| VTGN | 0.00% | 0.29% | -0.29% | $0 |
| CBIO | 0.00% | 0.27% | -0.27% | $0 |
Sector Allocation Over Time
Market Cap Concentration
| Tier | Holdings | Value | Weight |
|---|---|---|---|
| Mid Cap | 21 | $1.1B | 75.9% |
| Small Cap | 13 | $263M | 18.5% |
| Micro Cap | 7 | $80M | 5.6% |
Portfolio Analytics
Avg Market Cap
$3.0B
Median Market Cap
$2.1B
Avg P/E
57.5
Median P/E
41.0
Avg Dividend Yield
—%
Avg Beta
0.89
# Stocks
41
# ETFs / Funds
0
Top Holdings (41 total)
| # | Symbol | % Port | Shares | Value | Avg Price | Q/Q Value Chg | Share Chg | Chg % | Status |
|---|---|---|---|---|---|---|---|---|---|
| 1 | RLAY | 10.11% | 17,000,000 | $144M | $8.46 | $55M | — | — | |
| 2 | ALKS | 6.98% | 3,550,000 | $99M | $27.98 | $6M | +453,246 | +14.6% | |
| 3 | TYRA | 6.24% | 3,375,000 | $89M | $26.29 | $42M | — | — | |
| 4 | XENE | 5.67% | 1,800,000 | $81M | $44.82 | -$28M | -900,000 | -33.3% | |
| 5 | SYRE | 5.50% | 2,388,245 | $78M | $32.76 | $45M | +400,161 | +20.1% | |
| 6 | COGT | 5.48% | 2,196,845 | $78M | $35.52 | -$26M | -5,053,155 | -69.7% | |
| 7 | ELVN | 5.08% | 4,692,809 | $72M | $15.40 | -$24M | — | — | |
| 8 | CLDX | 4.90% | 2,565,000 | $70M | $27.16 | -$9M | -463,335 | -15.3% | |
| 9 | AMLX | 4.80% | 5,650,000 | $68M | $12.08 | $13M | +1,574,522 | +38.6% | |
| 10 | TERN | 4.19% | 1,475,000 | $60M | $40.40 | $17M | -4,225,000 | -74.1% | |
| 11 | KYMR | 4.10% | 750,000 | $58M | $77.81 | $16M | — | — | |
| 12 | SLNO | 3.90% | 1,200,000 | $56M | $46.30 | -$36M | -150,000 | -11.1% | |
| 13 | NUVL | 3.89% | 550,000 | $55M | $100.59 | -$66M | -850,000 | -60.7% | |
| 14 | ORKA | 3.73% | 1,753,054 | $53M | $30.31 | $19M | — | — | |
| 15 | NRIX | 3.03% | 2,275,000 | $43M | $18.97 | $8M | -1,505,055 | -39.8% | |
| 16 | PTGX | 2.76% | 450,000 | $39M | $87.34 | -$29M | -575,000 | -56.1% | |
| 17 | ASMB | 2.39% | 1,000,000 | $34M | $34.01 | $8M | — | — | |
| 18 | LBRX | 2.35% | 1,500,000 | $33M | $22.26 | $10M | — | — | |
| 19 | CTMX | 2.30% | 7,692,300 | $33M | $4.26 | $8M | — | — | |
| 20 | ANRO | 2.28% | 1,823,196 | $32M | $17.80 | — | +1,823,196 | — | NEW |
| 21 | PALI | 1.89% | 11,445,000 | $27M | $2.35 | — | +11,445,000 | — | NEW |
| 22 | CNTA | 1.76% | 1,000,000 | $25M | $25.01 | -$44M | -1,850,000 | -64.9% | |
| 23 | PEPG | 1.56% | 3,400,000 | $22M | $6.51 | $11M | +1,042,681 | +44.2% | |
| 24 | SABS | 1.16% | 4,401,500 | $16M | $3.74 | $8M | — | — | |
| 25 | REPL | 0.97% | 1,425,000 | $14M | $9.72 | — | +1,425,000 | — | NEW |
| 26 | IKT | 0.78% | 5,397,488 | $11M | $2.05 | $2M | — | — | |
| 27 | CTNM | 0.66% | 816,326 | $9M | $11.43 | — | +816,326 | — | NEW |
| 28 | AVTX | 0.62% | 483,000 | $9M | $18.16 | $3M | — | — | |
| 29 | RAPT | 0.60% | 250,000 | $8M | $33.87 | — | +250,000 | — | NEW |
| 30 | ATHA | 0.25% | 464,398 | $4M | $7.57 | — | +464,398 | — | NEW |
| 31 | DRUG | 0.10% | 18,851 | $1M | $78.04 | -$29M | -481,149 | -96.2% | |
| 32 | TNGX | —% | — | — | — | -$13M | -1,500,000 | -100.0% | SOLD |
| 33 | ENTA | —% | — | — | — | -$10M | -800,000 | -100.0% | SOLD |
| 34 | VTGN | —% | — | — | — | -$6M | -1,575,000 | -100.0% | SOLD |
| 35 | APGE | —% | — | — | — | -$12M | -290,000 | -100.0% | SOLD |
| 36 | VRDN | —% | — | — | — | -$69M | -3,200,000 | -100.0% | SOLD |
| 37 | MRUS | —% | — | — | — | -$332M | -3,525,000 | -100.0% | SOLD |
| 38 | CBIO | —% | — | — | — | -$5M | -450,829 | -100.0% | SOLD |
| 39 | PCSC | —% | — | — | — | -$8M | -750,000 | -100.0% | SOLD |
| 40 | CDTX | —% | — | — | — | -$56M | -585,000 | -100.0% | SOLD |
| 41 | AGIO | —% | — | — | — | -$94M | -2,338,287 | -100.0% | SOLD |