Asset Manager
← All Institutions
Frazier Life Sciences Management, L.P.
Market Value
$3.9B
+18.3%
Holdings
41
+1
New Purchases
6
Added To
6
Closed
3
Reduced
2
Top 10 Concentration
73.8%
Turnover
22.0%
Top Buys (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| MBX | 9.40% | 6.01% | +3.38% | $367M |
| MIRM | 23.00% | 21.47% | +1.53% | $899M |
| PBLS | 1.35% | 0.00% | +1.35% | $53M |
| ACHV | 1.27% | 0.00% | +1.27% | $50M |
| TRVI | 4.74% | 3.59% | +1.15% | $185M |
| ALLO | 1.19% | 0.28% | +0.91% | $47M |
| KRYS | 4.58% | 3.76% | +0.81% | $179M |
| DSGN | 0.67% | 0.00% | +0.67% | $26M |
| STTK | 0.67% | 0.00% | +0.67% | $26M |
| KLRA | 0.62% | 0.00% | +0.62% | $24M |
| RLAY | 0.49% | 0.00% | +0.49% | $19M |
| MNKD | 0.72% | 0.44% | +0.28% | $28M |
| AURA | 1.29% | 1.03% | +0.26% | $50M |
| CYTK | 2.53% | 2.31% | +0.21% | $99M |
| ALKS | 0.94% | 0.75% | +0.19% | $37M |
Top Sells (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| BBIO | 2.95% | 7.75% | -4.80% | $115M |
| KALV | 0.00% | 3.02% | -3.02% | $0 |
| RVMD | 0.00% | 1.99% | -1.99% | $0 |
| AGIO | 0.00% | 1.29% | -1.29% | $0 |
| PHAT | 3.46% | 4.19% | -0.73% | $135M |
| ARQT | 6.62% | 7.04% | -0.42% | $259M |
| ERAS | 11.71% | 12.09% | -0.38% | $458M |
| TARS | 1.17% | 1.55% | -0.37% | $46M |
| MAZE | 3.84% | 4.13% | -0.28% | $150M |
| LXEO | 0.57% | 0.77% | -0.19% | $22M |
| VOR | 1.20% | 1.37% | -0.18% | $47M |
| ZLAB | 0.92% | 1.08% | -0.16% | $36M |
| BCRX | 1.03% | 1.16% | -0.13% | $40M |
| VALN | 0.31% | 0.43% | -0.13% | $12M |
| IRON | 2.54% | 2.62% | -0.09% | $99M |
Sector Allocation Over Time
Market Cap Concentration
| Tier | Holdings | Value | Weight |
|---|---|---|---|
| Large Cap | 2 | $115M | 3.0% |
| Mid Cap | 15 | $2.7B | 69.0% |
| Small Cap | 21 | $1.1B | 27.3% |
| Micro Cap | 3 | $30M | 0.8% |
Portfolio Analytics
Avg Market Cap
$3.5B
Median Market Cap
$1.5B
Avg P/E
66.3
Median P/E
71.3
Avg Dividend Yield
—%
Avg Beta
0.92
# Stocks
41
# ETFs / Funds
0
Top Holdings (41 total)
| # | Symbol | % Port | Shares | Value | Avg Price | Q/Q Value Chg | Share Chg | Chg % | Status |
|---|---|---|---|---|---|---|---|---|---|
| 1 | MIRM | 23.00% | 7,679,684 | $899M | $117.07 | $190M | — | — | |
| 2 | ERAS | 11.71% | 24,975,188 | $458M | $18.32 | $58M | +300,000 | +1.2% | |
| 3 | MBX | 9.40% | 6,652,013 | $367M | $55.20 | $169M | — | — | |
| 4 | ARQT | 6.62% | 9,874,511 | $259M | $26.22 | $26M | — | — | |
| 5 | TRVI | 4.74% | 9,939,447 | $185M | $18.65 | $67M | -100 | — | |
| 6 | KRYS | 4.58% | 481,307 | $179M | $371.67 | $55M | — | — | |
| 7 | MAZE | 3.84% | 5,032,915 | $150M | $29.84 | $14M | +465,641 | +10.2% | |
| 8 | PHAT | 3.46% | 12,466,489 | $135M | $10.85 | -$3M | — | — | |
| 9 | PVLA | 3.45% | 882,400 | $135M | $152.82 | $25M | — | — | |
| 10 | BBIO | 2.95% | 1,548,139 | $115M | $74.48 | -$141M | -1,900,000 | -55.1% | |
| 11 | IRON | 2.54% | 1,354,852 | $99M | $73.14 | $12M | — | — | |
| 12 | CYTK | 2.53% | 1,159,879 | $99M | $85.19 | $22M | — | — | |
| 13 | DYN | 1.79% | 3,153,082 | $70M | $22.21 | $13M | — | — | |
| 14 | SVRA | 1.53% | 9,720,852 | $60M | $6.16 | $7M | — | — | |
| 15 | PBLS | 1.35% | 1,920,805 | $53M | $27.37 | — | +1,920,805 | — | NEW |
| 16 | AURA | 1.29% | 7,100,000 | $50M | $7.10 | $16M | +2,000,000 | +39.2% | |
| 17 | ACHV | 1.27% | 7,614,836 | $50M | $6.53 | — | +7,614,836 | — | NEW |
| 18 | VOR | 1.20% | 2,543,939 | $47M | $18.41 | $1M | — | — | |
| 19 | ALLO | 1.19% | 22,446,668 | $47M | $2.08 | $37M | +18,650,000 | +491.2% | |
| 20 | TARS | 1.17% | 728,644 | $46M | $62.94 | -$5M | — | — | |
| 21 | BCRX | 1.03% | 4,009,240 | $40M | $10.00 | $2M | — | — | |
| 22 | ALKS | 0.94% | 700,647 | $37M | $52.40 | $12M | — | — | |
| 23 | ACAD | 0.93% | 1,438,198 | $36M | $25.30 | $4M | — | — | |
| 24 | ZLAB | 0.92% | 1,902,320 | $36M | $19.00 | $361K | — | — | |
| 25 | MNKD | 0.72% | 6,600,000 | $28M | $4.26 | $14M | +700,000 | +11.9% | |
| 26 | DSGN | 0.67% | 1,809,854 | $26M | $14.47 | — | +1,809,854 | — | NEW |
| 27 | ACRS | 0.67% | 4,925,374 | $26M | $5.29 | $8M | — | — | |
| 28 | STTK | 0.67% | 3,750,000 | $26M | $6.94 | — | +3,750,000 | — | NEW |
| 29 | KLRA | 0.62% | 1,100,000 | $24M | $22.03 | — | +1,100,000 | — | NEW |
| 30 | GLUE | 0.62% | 1,000,000 | $24M | $24.20 | $8M | — | — | |
| 31 | LXEO | 0.57% | 4,824,725 | $22M | $4.66 | -$3M | +400,000 | +9.0% | |
| 32 | RLAY | 0.49% | 1,015,693 | $19M | $18.71 | — | +1,015,693 | — | NEW |
| 33 | EOLS | 0.47% | 2,630,665 | $18M | $6.94 | $7M | — | — | |
| 34 | IMCR | 0.39% | 484,782 | $15M | $31.75 | $776K | — | — | |
| 35 | VALN | 0.31% | 2,291,666 | $12M | $5.23 | -$2M | — | — | |
| 36 | AUTL | 0.18% | 4,447,910 | $7M | $1.60 | $979K | — | — | |
| 37 | XLO | 0.10% | 422,505 | $4M | $9.58 | $494K | — | — | |
| 38 | IBIO | 0.09% | 1,953,467 | $3M | $1.75 | -$293K | — | — | |
| 39 | AGIO | —% | — | — | — | -$42M | -1,256,080 | -100.0% | SOLD |
| 40 | KALV | —% | — | — | — | -$100M | -4,961,108 | -100.0% | SOLD |
| 41 | RVMD | —% | — | — | — | -$66M | -675,686 | -100.0% | SOLD |