Asset Manager
← All Institutions
Frazier Life Sciences Management, L.P.
Market Value
$2.8B
+29.7%
Holdings
49
-3
New Purchases
3
Added To
9
Closed
6
Reduced
7
Top 10 Concentration
68.7%
Turnover
18.4%
Top Buys (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| MIRM | 17.67% | 15.91% | +1.75% | $498M |
| MAZE | 4.20% | 2.58% | +1.62% | $118M |
| ABVX | 1.14% | 0.00% | +1.14% | $32M |
| MBX | 4.13% | 3.14% | +0.99% | $116M |
| CYTK | 1.74% | 0.84% | +0.89% | $49M |
| PVLA | 1.61% | 0.75% | +0.86% | $45M |
| TRVI | 3.33% | 2.58% | +0.75% | $94M |
| VALN | 0.99% | 0.38% | +0.61% | $28M |
| DYN | 1.22% | 0.66% | +0.56% | $34M |
| ACAD | 0.46% | 0.00% | +0.46% | $13M |
| ERAS | 1.76% | 1.33% | +0.43% | $50M |
| ASMB | 0.41% | 0.00% | +0.41% | $12M |
| SVRA | 1.45% | 1.20% | +0.25% | $41M |
| ARQT | 6.60% | 6.37% | +0.23% | $186M |
| ADVM | 0.33% | 0.11% | +0.23% | $9M |
Top Sells (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| VRNA | 12.81% | 14.73% | -1.92% | $361M |
| HLVX | 0.00% | 0.97% | -0.97% | $0 |
| CGON | 0.00% | 0.92% | -0.92% | $0 |
| IRON | 3.37% | 4.03% | -0.66% | $95M |
| RARE | 1.05% | 1.65% | -0.60% | $30M |
| COGT | 0.00% | 0.57% | -0.57% | $0 |
| ALKS | 0.75% | 1.32% | -0.57% | $21M |
| ORIC | 0.00% | 0.50% | -0.50% | $0 |
| MREO | 0.69% | 1.18% | -0.49% | $19M |
| BBIO | 7.08% | 7.55% | -0.47% | $200M |
| EOLS | 0.57% | 1.03% | -0.46% | $16M |
| JBIO | 0.43% | 0.81% | -0.38% | $12M |
| KALV | 2.18% | 2.54% | -0.37% | $61M |
| AURA | 1.12% | 1.47% | -0.35% | $32M |
| TVTX | 0.33% | 0.68% | -0.35% | $9M |
Sector Allocation Over Time
Market Cap Concentration
| Tier | Holdings | Value | Weight |
|---|---|---|---|
| Large Cap | 4 | $635M | 22.5% |
| Mid Cap | 19 | $1.4B | 49.1% |
| Small Cap | 20 | $736M | 26.1% |
| Micro Cap | 6 | $64M | 2.3% |
Portfolio Analytics
Avg Market Cap
$5.3B
Median Market Cap
$1.9B
Avg P/E
61.3
Median P/E
41.0
Avg Dividend Yield
—%
Avg Beta
0.80
# Stocks
49
# ETFs / Funds
0
Top Holdings (49 total)
| # | Symbol | % Port | Shares | Value | Avg Price | Q/Q Value Chg | Share Chg | Chg % | Status |
|---|---|---|---|---|---|---|---|---|---|
| 1 | MIRM | 17.67% | 6,795,121 | $498M | $73.31 | $152M | — | — | |
| 2 | VRNA | 12.81% | 3,383,950 | $361M | $106.71 | $41M | — | — | |
| 3 | BBIO | 7.08% | 3,845,457 | $200M | $51.94 | $36M | +45,000 | +1.2% | |
| 4 | ARQT | 6.60% | 9,874,511 | $186M | $18.85 | $48M | — | — | |
| 5 | PHAT | 5.20% | 12,466,489 | $147M | $11.77 | $27M | — | — | |
| 6 | KRYS | 4.31% | 688,460 | $122M | $176.53 | $27M | — | — | |
| 7 | MAZE | 4.20% | 4,567,274 | $118M | $25.93 | $62M | -1 | — | |
| 8 | MBX | 4.13% | 6,652,013 | $116M | $17.50 | $48M | +666,666 | +11.1% | |
| 9 | IRON | 3.37% | 1,438,534 | $95M | $66.08 | $7M | -216,300 | -13.1% | |
| 10 | TRVI | 3.33% | 10,259,409 | $94M | $9.15 | $38M | — | — | |
| 11 | TARS | 2.46% | 1,167,527 | $69M | $59.43 | $13M | -230,000 | -16.5% | |
| 12 | KALV | 2.18% | 5,039,867 | $61M | $12.18 | $6M | +152,000 | +3.1% | |
| 13 | ZLAB | 1.96% | 1,627,320 | $55M | $33.89 | $9M | +319,182 | +24.4% | |
| 14 | AGIO | 1.82% | 1,279,754 | $51M | $40.14 | $9M | — | — | |
| 15 | ERAS | 1.76% | 22,729,436 | $50M | $2.18 | $21M | — | — | |
| 16 | CYTK | 1.74% | 890,445 | $49M | $54.96 | $31M | +335,714 | +60.5% | |
| 17 | RVMD | 1.65% | 997,455 | $47M | $46.70 | $10M | — | — | |
| 18 | PVLA | 1.61% | 722,400 | $45M | $62.69 | $29M | — | — | |
| 19 | SVRA | 1.45% | 11,462,301 | $41M | $3.57 | $15M | — | — | |
| 20 | DYN | 1.22% | 2,718,105 | $34M | $12.65 | $20M | +1,212,121 | +80.5% | |
| 21 | ABVX | 1.14% | 378,300 | $32M | $84.90 | — | +378,300 | — | NEW |
| 22 | AURA | 1.12% | 5,100,000 | $32M | $6.18 | -$408K | — | — | |
| 23 | RARE | 1.05% | 983,715 | $30M | $30.08 | -$6M | — | — | |
| 24 | LXEO | 1.04% | 4,424,725 | $29M | $6.64 | $12M | — | — | |
| 25 | VALN | 0.99% | 2,291,666 | $28M | $12.20 | $20M | +833,333 | +57.1% | |
| 26 | RNAM | 0.97% | 625,000 | $27M | $43.57 | $9M | — | — | |
| 27 | ALKS | 0.75% | 700,647 | $21M | $30.00 | -$8M | -300,000 | -30.0% | |
| 28 | MREO | 0.69% | 9,440,112 | $19M | $2.06 | -$6M | — | — | |
| 29 | AKRO | 0.62% | 366,784 | $17M | $47.48 | -$2M | — | — | |
| 30 | PCVX | 0.61% | 474,405 | $17M | $36.02 | $2M | — | — | |
| 31 | EOLS | 0.57% | 2,630,665 | $16M | $6.14 | -$6M | +195,115 | +8.0% | |
| 32 | DSGN | 0.52% | 1,953,547 | $15M | $7.53 | $8M | — | — | |
| 33 | IMCR | 0.50% | 384,782 | $14M | $36.33 | $2M | — | — | |
| 34 | ACAD | 0.46% | 613,837 | $13M | $21.34 | — | +613,837 | — | NEW |
| 35 | JBIO | 0.43% | 1,413,280 | $12M | $8.63 | -$6M | -358,836 | -20.2% | |
| 36 | ASMB | 0.41% | 456,249 | $12M | $25.60 | — | +456,249 | — | NEW |
| 37 | ADVM | 0.33% | 2,077,431 | $9M | $4.53 | $7M | +1,008,187 | +94.3% | |
| 38 | TVTX | 0.33% | 392,092 | $9M | $23.90 | -$5M | -610,000 | -60.9% | |
| 39 | AUTL | 0.27% | 4,623,324 | $8M | $1.63 | -$3M | — | — | |
| 40 | MGNX | 0.19% | 3,175,665 | $5M | $1.68 | $1M | — | — | |
| 41 | SLN | 0.18% | 970,130 | $5M | $5.19 | -$592K | — | — | |
| 42 | ALLO | 0.17% | 3,868,750 | $5M | $1.24 | $426K | — | — | |
| 43 | CBIO | 0.12% | 272,951 | $3M | $11.89 | -$4M | -180,734 | -39.8% | |
| 44 | CGON | —% | — | — | — | -$20M | -770,000 | -100.0% | SOLD |
| 45 | COGT | —% | — | — | — | -$12M | -1,734,601 | -100.0% | SOLD |
| 46 | ORIC | —% | — | — | — | -$11M | -1,065,334 | -100.0% | SOLD |
| 47 | ORKA | —% | — | — | — | -$7M | -583,327 | -100.0% | SOLD |
| 48 | ELEV | —% | — | — | — | -$2M | -5,993,579 | -100.0% | SOLD |
| 49 | HLVX | —% | — | — | — | -$21M | -10,617,062 | -100.0% | SOLD |