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Amylyx Pharmaceuticals, Inc.
1W: -0.9% 1M: -8.1% 3M: +38.6% YTD: +137.2% 1Y: +89.3% 3Y: +63.7%
$28.30
+1.21 (+4.47%)
After Hours: $27.48 (-0.82, -2.92%)
Weekly Expected Move ±6.1%
$24 $26 $27 $29 $31
NASDAQ · Healthcare · Biotechnology · Tech Score Sell · Power 40 · $3.4B mcap · 97M float · 2.19% daily turnover · Short 49% of daily vol
Credit Risk of going bust: lower than 78% of companies Debt: 0.2% of company value Bonds: none of note held by US funds details ▾
Of US companies ranked in the safest four tenths, about 1 in 3,500 filed for bankruptcy within a year (2020-2025).
If the stock fell to about $0.01 (down more than 99.9%), Amylyx Pharmaceuticals, Inc. would be worth roughly what it owes.
Total debt $5.3M against a stock market value of $3.40B.
Distance to default 9.13 (Merton model): prices to 2026-10-26, balance sheet 2026-06-30, debt counted $2.6M (short-term plus half of long-term), stock volatility 75.9%; Altman Z'' 1.60. A ranking and a back-test, not a forecast.
US fund filings (SEC N-PORT) show under $25M of this company's bonds, so there is no bond page. Its debt may be bank loans or privately placed. How these are computed.

🏦 Institutional Activity

Latest: Q2 2026
223
Institutions Holding
+18 vs prior
61.0%
Ownership
+14.44%
54 New
70 Increased
73 Reduced
13 Closed

👔 Insider Trades

25 records
Date Name Title Type Shares Price Value Filing
2026-10-05 MILNE GEORGE M JR director S-Sale 30,000 $27.70 $831K Filing
2026-09-10 Mazzariello Gina officer: chief legal officer S-Sale 11 $33.34 $367 Filing
2026-09-10 Mazzariello Gina officer: chief legal officer S-Sale 9,525 $32.46 $309K Filing
2026-09-10 Cohen Joshua B officer: co-chief executive officer S-Sale 919 $33.15 $30K Filing
2026-09-10 Cohen Joshua B officer: co-chief executive officer S-Sale 29,545 $32.16 $950K Filing
2026-09-10 Klee Justin B. officer: co-chief executive officer S-Sale 1,439 $33.16 $48K Filing
2026-09-10 Klee Justin B. officer: co-chief executive officer S-Sale 29,025 $32.13 $933K Filing
2026-09-10 FRATES JAMES M officer: chief financial officer S-Sale 1,042 $33.23 $35K Filing
2026-09-10 FRATES JAMES M officer: chief financial officer S-Sale 9,768 $32.27 $315K Filing
2026-09-10 Bedrosian Camille L officer: chief medical officer S-Sale 2,081 $33.09 $69K Filing
2026-09-10 Bedrosian Camille L officer: chief medical officer S-Sale 7,947 $32.21 $256K Filing
2026-08-18 Cohen Joshua B officer: co-chief executive officer A-Grant/Award 60,039 $— $0 Filing
2026-08-18 Bedrosian Camille L officer: chief medical officer A-Grant/Award 22,807 $— $0 Filing
2026-08-18 Mazzariello Gina officer: chief legal officer A-Grant/Award 21,284 $— $0 Filing
2026-08-18 Klee Justin B. officer: co-chief executive officer A-Grant/Award 60,039 $— $0 Filing
2026-08-18 FRATES JAMES M officer: chief financial officer A-Grant/Award 22,807 $— $0 Filing
2026-07-10 Mazzariello Gina officer: chief legal officer S-Sale 15,000 $17.61 $264K Filing
2026-07-09 Mazzariello Gina officer: chief legal officer S-Sale 15,000 $18.32 $275K Filing
2026-05-21 Firestone Karen director P-Purchase 3,800 $13.51 $51K Filing
2026-03-02 Cohen Joshua B officer: co-chief executive officer S-Sale 29,282 $14.48 $424K Filing
2026-03-02 Bedrosian Camille L officer: chief medical officer S-Sale 6,461 $14.58 $94K Filing
2026-03-02 Mazzariello Gina officer: chief legal officer S-Sale 6,844 $14.52 $99K Filing
2026-03-02 Klee Justin B. officer: co-chief executive officer S-Sale 29,282 $14.47 $424K Filing
2026-03-02 FRATES JAMES M officer: chief financial officer S-Sale 7,909 $14.52 $115K Filing
2026-02-23 Mazzariello Gina officer: chief legal officer S-Sale 3,419 $14.14 $48K Filing

🏛️ Congressional Trades

1 records
Date Politician Chamber Type Amount Filing
2022-10-12 Chris Jacobs House Buy $1,001 - $15,000 Filing

🏦 Top Institutional Holders

20 holders
Holder Shares Value Date Reported Filing
FMR LLC 16,727,909 $300M +97,368 2026-06-30 Filing
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PERCEPTIVE ADVISORS LLC 8,334,882 $150M +50,000 2026-06-30 Filing
TCG Crossover Management, LLC 6,243,812 $112M — 2026-06-30 Filing
Commodore Capital LP 5,650,000 $101M — 2026-06-30 Filing
Jupiter Topco LLC 5,236,102 $94M +5,236,102 2026-06-30 Filing
Saturn V Capital Management LP 4,624,101 $83M +274,216 2026-06-30 Filing
VANGUARD CAPITAL MANAGEMENT LLC 4,224,224 $76M +82,649 2026-06-30 Filing
MORGAN STANLEY 3,130,808 $56M +955,261 2026-06-30 Filing
Driehaus Capital Management LLC 3,036,970 $55M +49,823 2026-06-30 Filing
First Light Asset Management, LLC 3,023,256 $54M -167,389 2026-06-30 Filing
FRANKLIN RESOURCES INC 2,950,225 $53M +688,656 2026-06-30 Filing
GOLDMAN SACHS GROUP INC 2,858,239 $51M +232,248 2026-06-30 Filing
STATE STREET CORP 2,603,337 $47M +240,176 2026-06-30 Filing
GEODE CAPITAL MANAGEMENT, LLC 2,335,315 $42M +124,383 2026-06-30 Filing
JPMORGAN CHASE & CO 1,863,650 $35M +1,703,987 2026-06-30 Filing
ADAGE CAPITAL PARTNERS GP, L.L.C. 1,900,000 $34M -1,660,764 2026-06-30 Filing
Siren, L.L.C. 1,480,586 $27M +250,586 2026-06-30 Filing
EVENTIDE ASSET MANAGEMENT, LLC 1,327,536 $24M -186,422 2026-06-30 Filing
683 Capital Management, LLC 1,279,512 $23M -250,488 2026-06-30 Filing

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For informational purposes only. Not investment advice. Data sourced from SEC filings. Privacy Terms