Asset Manager
← All Institutions
Siren, L.L.C.
Market Value
$4.9B
+39.1%
Holdings
119
-6
New Purchases
24
Added To
31
Closed
7
Reduced
20
Top 10 Concentration
45.2%
Turnover
26.1%
Top Buys (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| PBLS | 1.68% | 0.00% | +1.68% | $82M |
| ABVX | 1.57% | 0.00% | +1.57% | $77M |
| COAG | 1.57% | 0.00% | +1.57% | $77M |
| MANE | 4.18% | 2.71% | +1.46% | $204M |
| RLAY | 1.40% | 0.00% | +1.40% | $68M |
| ELVN | 1.85% | 0.83% | +1.01% | $90M |
| KLRA | 1.00% | 0.00% | +1.00% | $49M |
| DFTX | 1.37% | 0.50% | +0.87% | $67M |
| RYTM | 2.59% | 1.80% | +0.79% | $126M |
| COF | 0.71% | 0.00% | +0.71% | $34M |
| TNGX | 3.96% | 3.38% | +0.59% | $193M |
| SYRE | 1.76% | 1.18% | +0.59% | $86M |
| ORKA | 0.49% | 0.00% | +0.49% | $24M |
| SPTX | 0.49% | 0.00% | +0.49% | $24M |
| TYRA | 0.48% | 0.00% | +0.48% | $23M |
Top Sells (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| SRRK | 10.80% | 15.18% | -4.38% | $527M |
| EWTX | 2.65% | 3.98% | -1.33% | $129M |
| ONC | 2.72% | 3.94% | -1.22% | $133M |
| CNTA | 0.00% | 1.19% | -1.19% | $0 |
| ERAS | 4.28% | 5.19% | -0.91% | $209M |
| CRNX | 1.09% | 1.97% | -0.88% | $53M |
| GPCR | 0.96% | 1.83% | -0.87% | $47M |
| OLMA | 1.25% | 2.02% | -0.78% | $61M |
| KYMR | 6.91% | 7.57% | -0.67% | $337M |
| XENE | 1.63% | 2.19% | -0.55% | $80M |
| FULC | 0.00% | 0.51% | -0.51% | $0 |
| STOK | 1.34% | 1.85% | -0.51% | $65M |
| DBVT | 0.62% | 1.11% | -0.48% | $30M |
| IRON | 1.33% | 1.80% | -0.47% | $65M |
| ORIC | 0.67% | 1.08% | -0.42% | $32M |
Sector Allocation Over Time
Market Cap Concentration
| Tier | Holdings | Value | Weight |
|---|---|---|---|
| Mega Cap | 11 | $119M | 2.4% |
| Large Cap | 22 | $420M | 8.6% |
| Mid Cap | 32 | $2.9B | 60.1% |
| Small Cap | 33 | $1.2B | 25.0% |
| Micro Cap | 21 | $186M | 3.8% |
Portfolio Analytics
Avg Market Cap
$212.9B
Median Market Cap
$3.2B
Avg P/E
42.4
Median P/E
26.1
Avg Dividend Yield
0.00%
Avg Beta
1.07
# Stocks
119
# ETFs / Funds
0
Top Holdings (119 total)
| # | Symbol | % Port | Shares | Value | Avg Price | Q/Q Value Chg | Share Chg | Chg % | Status |
|---|---|---|---|---|---|---|---|---|---|
| 1 | SRRK | 10.80% | 9,575,013 | $527M | $55.00 | -$6M | -1,250,000 | -11.6% | |
| 2 | KYMR | 6.91% | 2,935,830 | $337M | $114.67 | $71M | -251,000 | -7.9% | |
| 3 | ERAS | 4.28% | 11,397,781 | $209M | $18.32 | $27M | +153,535 | +1.4% | |
| 4 | MANE | 4.18% | 1,655,374 | $204M | $122.94 | $108M | +150,000 | +10.0% | |
| 5 | TNGX | 3.96% | 6,179,364 | $193M | $31.26 | $75M | +522,259 | +9.2% | |
| 6 | RVMD | 3.46% | 900,000 | $169M | $187.28 | $61M | -210,980 | -19.0% | |
| 7 | BCAX | 3.41% | 5,602,970 | $166M | $29.69 | $51M | -200,000 | -3.5% | |
| 8 | ARWR | 2.87% | 1,715,476 | $140M | $81.51 | $39M | +100,000 | +6.2% | |
| 9 | ONC | 2.72% | 465,000 | $133M | $284.97 | -$6M | — | — | |
| 10 | EWTX | 2.65% | 3,184,629 | $129M | $40.63 | -$10M | -1,245,634 | -28.1% | |
| 11 | RYTM | 2.59% | 1,136,275 | $126M | $111.03 | $63M | +410,764 | +56.6% | |
| 12 | LXRX | 2.18% | 44,303,518 | $106M | $2.40 | $37M | — | — | |
| 13 | ELVN | 1.85% | 1,774,411 | $90M | $50.75 | $61M | +1,028,185 | +137.8% | |
| 14 | SYRE | 1.76% | 968,598 | $86M | $88.78 | $45M | +150,000 | +18.3% | |
| 15 | PBLS | 1.68% | 2,992,259 | $82M | $27.37 | — | +2,992,259 | — | NEW |
| 16 | XENE | 1.63% | 1,318,564 | $80M | $60.36 | $3M | — | — | |
| 17 | SLDB | 1.58% | 7,690,405 | $77M | $9.99 | $21M | — | — | |
| 18 | ABVX | 1.57% | 576,000 | $77M | $133.26 | — | +576,000 | — | NEW |
| 19 | COAG | 1.57% | 2,086,834 | $77M | $36.73 | — | +2,086,834 | — | NEW |
| 20 | RCUS | 1.53% | 2,420,430 | $75M | $30.83 | $10M | -586,647 | -19.5% | |
| 21 | COGT | 1.48% | 1,859,279 | $72M | $38.70 | $6M | +150,000 | +8.8% | |
| 22 | RLAY | 1.40% | 3,650,000 | $68M | $18.71 | — | +3,650,000 | — | NEW |
| 23 | TSHA | 1.38% | 9,846,579 | $67M | $6.81 | $28M | +1,016,666 | +11.5% | |
| 24 | DFTX | 1.37% | 1,419,493 | $67M | $47.04 | $49M | +500,000 | +54.4% | |
| 25 | STOK | 1.34% | 1,995,347 | $65M | $32.72 | $319K | — | — | |
| 26 | IRON | 1.33% | 888,401 | $65M | $73.14 | $2M | -100,000 | -10.1% | |
| 27 | CYTK | 1.33% | 758,952 | $65M | $85.19 | $24M | +145,000 | +23.6% | |
| 28 | SEPN | 1.31% | 1,900,000 | $64M | $33.49 | $16M | -100,000 | -5.0% | |
| 29 | OLMA | 1.25% | 4,856,949 | $61M | $12.51 | -$10M | +100,000 | +2.1% | |
| 30 | CRNX | 1.09% | 1,420,788 | $53M | $37.42 | -$16M | -482,848 | -25.4% | |
| 31 | KLRA | 1.00% | 2,214,286 | $49M | $22.03 | — | +2,214,286 | — | NEW |
| 32 | DYN | 0.97% | 2,129,125 | $47M | $22.21 | $7M | -100,000 | -4.5% | |
| 33 | GPCR | 0.96% | 872,967 | $47M | $53.67 | -$17M | -455,731 | -34.3% | |
| 34 | PVLA | 0.81% | 257,485 | $39M | $152.82 | $7M | — | — | |
| 35 | SLN | 0.75% | 3,311,438 | $36M | $10.98 | $21M | +400,000 | +13.7% | |
| 36 | DNLI | 0.74% | 1,396,513 | $36M | $25.72 | $9M | — | — | |
| 37 | RELY | 0.71% | 1,543,271 | $35M | $22.41 | $10M | — | — | |
| 38 | CGEM | 0.71% | 1,893,410 | $34M | $18.21 | $18M | +700,000 | +58.7% | |
| 39 | COF | 0.71% | 171,615 | $34M | $200.62 | — | +171,615 | — | NEW |
| 40 | TRVI | 0.68% | 1,786,867 | $33M | $18.65 | $12M | — | — | |
| 41 | ORIC | 0.67% | 2,998,192 | $32M | $10.83 | -$6M | — | — | |
| 42 | GOOGL | 0.66% | 90,000 | $32M | $357.37 | $13M | +24,297 | +37.0% | |
| 43 | DBVT | 0.62% | 1,857,362 | $30M | $16.40 | -$8M | — | — | |
| 44 | ABSI | 0.59% | 2,474,764 | $29M | $11.59 | $23M | +674,764 | +37.5% | |
| 45 | SION | 0.55% | 610,515 | $27M | $43.99 | $15M | +310,515 | +103.5% | |
| 46 | RAPP | 0.55% | 641,469 | $27M | $41.67 | $7M | — | — | |
| 47 | AMLX | 0.55% | 1,480,586 | $27M | $17.96 | $9M | +250,586 | +20.4% | |
| 48 | ANNX | 0.52% | 4,458,646 | $25M | $5.71 | $4M | +500,000 | +12.6% | |
| 49 | MNPR | 0.51% | 270,118 | $25M | $92.59 | $10M | — | — | |
| 50 | ORKA | 0.49% | 250,000 | $24M | $95.17 | — | +250,000 | — | NEW |
| 51 | SPTX | 0.49% | 1,095,316 | $24M | $21.72 | — | +1,095,316 | — | NEW |
| 52 | GLTO | 0.48% | 900,000 | $23M | $26.01 | $99K | — | — | |
| 53 | TYRA | 0.48% | 725,000 | $23M | $31.94 | — | +725,000 | — | NEW |
| 54 | ZURA | 0.45% | 3,734,866 | $22M | $5.90 | -$187K | — | — | |
| 55 | TSM | 0.44% | 44,700 | $21M | $477.57 | $7M | +2,500 | +5.9% | |
| 56 | NVDA | 0.39% | 95,000 | $19M | $200.09 | $3M | +5,915 | +6.6% | |
| 57 | RZLT | 0.36% | 3,328,287 | $17M | $5.20 | $7M | — | — | |
| 58 | MPLT | 0.33% | 450,000 | $16M | $35.84 | $7M | — | — | |
| 59 | NMRA | 0.30% | 8,497,822 | $14M | $1.70 | -$2M | — | — | |
| 60 | NBIS | 0.29% | 52,000 | $14M | $276.17 | $3M | -61,614 | -54.2% | |
| 61 | MSFT | 0.29% | 37,500 | $14M | $373.02 | -$1M | -3,880 | -9.4% | |
| 62 | CTMX | 0.27% | 3,457,711 | $13M | $3.75 | -$3M | — | — | |
| 63 | GENB | 0.25% | 736,104 | $12M | $16.87 | $3M | — | — | |
| 64 | IKT | 0.24% | 5,850,000 | $12M | $2.03 | $2M | — | — | |
| 65 | ADAG | 0.23% | 2,666,666 | $11M | $4.20 | — | +2,666,666 | — | NEW |
| 66 | ENGN | 0.22% | 6,256,662 | $11M | $1.73 | — | +6,256,662 | — | NEW |
| 67 | WHWK | 0.22% | 2,337,102 | $11M | $4.58 | $4M | +255,102 | +12.2% | |
| 68 | DDOG | 0.21% | 40,000 | $10M | $260.36 | $4M | -14,300 | -26.3% | |
| 69 | NOW | 0.20% | 100,000 | $10M | $99.28 | $823K | +12,910 | +14.8% | |
| 70 | AVGO | 0.19% | 25,000 | $9M | $377.75 | $5M | +10,000 | +66.7% | |
| 71 | IONQ | 0.19% | 170,000 | $9M | $53.26 | $4M | — | — | |
| 72 | FROG | 0.18% | 95,500 | $9M | $90.88 | $3M | -33,316 | -25.9% | |
| 73 | IREN | 0.16% | 175,000 | $8M | $45.73 | $7M | +131,900 | +306.0% | |
| 74 | AMZN | 0.16% | 32,500 | $8M | $238.34 | -$2M | -14,141 | -30.3% | |
| 75 | CRWD | 0.16% | 10,000 | $8M | $763.14 | -$1M | -13,070 | -56.6% | |
| 76 | DSGN | 0.16% | 523,212 | $8M | $14.47 | — | +523,212 | — | NEW |
| 77 | PDD | 0.15% | 95,000 | $7M | $76.28 | -$1M | +11,599 | +13.9% | |
| 78 | MSLE | 0.14% | 892,074 | $7M | $7.77 | $2M | — | — | |
| 79 | DT | 0.14% | 155,000 | $7M | $43.91 | $1M | +5,000 | +3.3% | |
| 80 | TENX | 0.13% | 427,141 | $6M | $14.55 | -$615K | — | — | |
| 81 | VTVT | 0.13% | 163,000 | $6M | $37.65 | -$328K | — | — | |
| 82 | ELOX | 0.11% | 400,000 | $6M | $13.88 | — | +400,000 | — | NEW |
| 83 | AGMB | 0.11% | 411,250 | $5M | $12.98 | $1M | — | — | |
| 84 | BABA | 0.10% | 50,000 | $5M | $95.98 | — | +50,000 | — | NEW |
| 85 | KRRO | 0.09% | 347,718 | $5M | $13.18 | $647K | — | — | |
| 86 | CLBT | 0.09% | 311,544 | $5M | $14.60 | $255K | — | — | |
| 87 | ADGI | 0.09% | 5,000,000 | $4M | $0.87 | -$838K | +1,000,000 | +25.0% | |
| 88 | OUST | 0.09% | 67,500 | $4M | $62.52 | — | +67,500 | — | NEW |
| 89 | PALI | 0.09% | 2,000,000 | $4M | $2.09 | — | +2,000,000 | — | NEW |
| 90 | AEVA | 0.09% | 145,459 | $4M | $28.72 | $3M | +35,459 | +32.2% | |
| 91 | SEER | 0.08% | 2,458,673 | $4M | $1.66 | -$49K | — | — | |
| 92 | IMAB | 0.08% | 2,004,739 | $4M | $1.95 | -$3M | -995,261 | -33.2% | |
| 93 | GTLB | 0.08% | 125,000 | $4M | $30.53 | $2M | +25,000 | +25.0% | |
| 94 | ODTX | 0.08% | 200,000 | $4M | $18.71 | — | +200,000 | — | NEW |
| 95 | FHTX | 0.07% | 720,720 | $4M | $4.88 | $72K | — | — | |
| 96 | AGEN | 0.07% | 1,064,250 | $3M | $3.06 | -$298K | — | — | |
| 97 | MNDY | 0.06% | 42,500 | $3M | $72.39 | $1M | +17,500 | +70.0% | |
| 98 | ZTS | 0.05% | 35,000 | $3M | $71.86 | — | +35,000 | — | NEW |
| 99 | WK | 0.04% | 45,000 | $2M | $48.51 | -$3M | -47,500 | -51.4% | |
| 100 | NFLX | 0.04% | 25,000 | $2M | $71.40 | — | +25,000 | — | NEW |