Asset Manager
← All Institutions
Siren, L.L.C.
Market Value
$3.1B
+28.5%
Holdings
123
+2
New Purchases
18
Added To
28
Closed
24
Reduced
23
Top 10 Concentration
50.4%
Turnover
34.1%
Top Buys (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| OLMA | 2.68% | 0.00% | +2.68% | $83M |
| RVMD | 3.45% | 2.03% | +1.42% | $106M |
| GPCR | 2.44% | 1.20% | +1.24% | $75M |
| SRRK | 15.48% | 14.37% | +1.11% | $477M |
| EWTX | 3.65% | 2.64% | +1.01% | $112M |
| RAPT | 1.51% | 0.62% | +0.89% | $47M |
| COGT | 1.88% | 1.03% | +0.85% | $58M |
| MLYS | 0.82% | 0.00% | +0.82% | $25M |
| FULC | 0.72% | 0.00% | +0.72% | $22M |
| RCUS | 2.33% | 1.65% | +0.67% | $72M |
| SYRE | 0.87% | 0.26% | +0.61% | $27M |
| ADGI | 0.32% | 0.00% | +0.32% | $10M |
| TSHA | 1.81% | 1.50% | +0.31% | $56M |
| TNGX | 2.35% | 2.06% | +0.29% | $72M |
| ERAS | 1.06% | 0.80% | +0.26% | $33M |
Top Sells (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| RNAM | 0.00% | 2.34% | -2.34% | $0 |
| ONC | 4.93% | 7.01% | -2.08% | $152M |
| RZLT | 0.00% | 1.91% | -1.91% | $0 |
| KRRO | 0.09% | 0.84% | -0.75% | $3M |
| LXRX | 1.45% | 2.19% | -0.74% | $45M |
| QURE | 0.00% | 0.67% | -0.67% | $0 |
| CRNX | 2.28% | 2.93% | -0.66% | $70M |
| ARWR | 3.23% | 3.84% | -0.61% | $100M |
| RAPP | 0.70% | 1.31% | -0.61% | $21M |
| BCAX | 2.85% | 3.44% | -0.59% | $88M |
| AVBP | 0.00% | 0.54% | -0.54% | $0 |
| RELY | 0.72% | 1.10% | -0.38% | $22M |
| RYTM | 1.74% | 2.11% | -0.37% | $54M |
| APLS | 2.10% | 2.43% | -0.33% | $65M |
| DYN | 2.22% | 2.50% | -0.27% | $69M |
Sector Allocation Over Time
Market Cap Concentration
| Tier | Holdings | Value | Weight |
|---|---|---|---|
| Mega Cap | 10 | $54M | 1.7% |
| Large Cap | 29 | $428M | 13.9% |
| Mid Cap | 35 | $1.8B | 57.9% |
| Small Cap | 30 | $725M | 23.5% |
| Micro Cap | 19 | $89M | 2.9% |
Portfolio Analytics
Avg Market Cap
$207.2B
Median Market Cap
$3.5B
Avg P/E
70.0
Median P/E
36.7
Avg Dividend Yield
0.00%
Avg Beta
1.21
# Stocks
123
# ETFs / Funds
0
Top Holdings (123 total)
| # | Symbol | % Port | Shares | Value | Avg Price | Q/Q Value Chg | Share Chg | Chg % | Status |
|---|---|---|---|---|---|---|---|---|---|
| 1 | SRRK | 15.48% | 10,825,013 | $477M | $44.05 | $132M | +1,575,008 | +17.0% | |
| 2 | KYMR | 8.30% | 3,286,830 | $256M | $77.81 | $62M | -141,320 | -4.1% | |
| 3 | ONC | 4.93% | 500,000 | $152M | $303.81 | -$16M | +7,010 | +1.4% | |
| 4 | EWTX | 3.65% | 4,529,990 | $112M | $24.82 | $49M | +632,891 | +16.2% | |
| 5 | RVMD | 3.45% | 1,335,075 | $106M | $79.65 | $58M | +291,355 | +27.9% | |
| 6 | CNTA | 3.27% | 4,027,517 | $101M | $25.01 | $22M | +800,000 | +24.8% | |
| 7 | ARWR | 3.23% | 1,500,476 | $100M | $66.39 | $8M | -1,169,404 | -43.8% | |
| 8 | BCAX | 2.85% | 5,216,969 | $88M | $16.83 | $5M | — | — | |
| 9 | OLMA | 2.68% | 3,300,700 | $83M | $25.00 | — | +3,300,700 | — | NEW |
| 10 | IRON | 2.55% | 988,401 | $78M | $79.41 | $18M | +75,000 | +8.2% | |
| 11 | GPCR | 2.44% | 1,078,698 | $75M | $69.55 | $46M | +51,887 | +5.0% | |
| 12 | TNGX | 2.35% | 8,165,374 | $72M | $8.86 | $23M | +2,282,186 | +38.8% | |
| 13 | RCUS | 2.33% | 3,007,077 | $72M | $23.83 | $32M | +95,000 | +3.3% | |
| 14 | STOK | 2.32% | 2,247,347 | $71M | $31.74 | $19M | — | — | |
| 15 | CRNX | 2.28% | 1,507,636 | $70M | $46.55 | -$150K | -180,975 | -10.7% | |
| 16 | DYN | 2.22% | 3,502,941 | $69M | $19.56 | $9M | -1,226,233 | -25.9% | |
| 17 | APLS | 2.10% | 2,578,396 | $65M | $25.12 | $6M | — | — | |
| 18 | COGT | 1.88% | 1,629,279 | $58M | $35.52 | $33M | -95,000 | -5.5% | |
| 19 | SEPN | 1.81% | 2,000,000 | $56M | $27.88 | $14M | -202,514 | -9.2% | |
| 20 | TSHA | 1.81% | 10,129,913 | $56M | $5.50 | $20M | -884,824 | -8.0% | |
| 21 | RYTM | 1.74% | 499,975 | $54M | $107.04 | $3M | — | — | |
| 22 | RAPT | 1.51% | 1,375,000 | $47M | $33.87 | $32M | +794,534 | +136.9% | |
| 23 | TBLA | 1.49% | 9,969,495 | $46M | $4.61 | $12M | — | — | |
| 24 | LXRX | 1.45% | 38,918,903 | $45M | $1.15 | -$8M | — | — | |
| 25 | WVE | 1.35% | 2,450,000 | $42M | $17.00 | $15M | -1,246,322 | -33.7% | |
| 26 | XENE | 1.18% | 812,761 | $36M | $44.82 | $4M | — | — | |
| 27 | ERAS | 1.06% | 8,757,249 | $33M | $3.72 | $13M | — | — | |
| 28 | TRVI | 0.93% | 2,286,867 | $29M | $12.52 | $5M | -250,000 | -9.8% | |
| 29 | SYRE | 0.87% | 818,598 | $27M | $32.76 | $21M | +450,000 | +122.1% | |
| 30 | MLYS | 0.82% | 699,999 | $25M | $36.29 | — | +699,999 | — | NEW |
| 31 | DNLI | 0.75% | 1,396,513 | $23M | $16.51 | $11M | +575,000 | +70.0% | |
| 32 | RELY | 0.72% | 1,618,271 | $22M | $13.80 | -$4M | — | — | |
| 33 | FULC | 0.72% | 1,950,000 | $22M | $11.31 | — | +1,950,000 | — | NEW |
| 34 | RAPP | 0.70% | 708,469 | $21M | $30.34 | -$10M | -345,000 | -32.8% | |
| 35 | SLN | 0.57% | 2,911,438 | $18M | $6.08 | $3M | — | — | |
| 36 | IHS | 0.57% | 2,357,520 | $18M | $7.46 | $2M | — | — | |
| 37 | GOSS | 0.52% | 5,208,968 | $16M | $3.10 | $2M | — | — | |
| 38 | UPB | 0.52% | 588,450 | $16M | $27.15 | $1M | -200,000 | -25.4% | |
| 39 | BCYC | 0.46% | 2,012,752 | $14M | $7.08 | -$1M | — | — | |
| 40 | CGEM | 0.40% | 1,193,410 | $12M | $10.35 | $5M | — | — | |
| 41 | SION | 0.40% | 300,000 | $12M | $41.14 | $3M | -25,000 | -7.7% | |
| 42 | IMAB | 0.39% | 3,000,000 | $12M | $3.98 | $8M | +1,834,043 | +157.3% | |
| 43 | AMZN | 0.39% | 51,500 | $12M | $230.82 | -$958K | -7,000 | -12.0% | |
| 44 | NMRA | 0.37% | 6,288,783 | $11M | $1.79 | $3M | +1,930,500 | +44.3% | |
| 45 | ADGI | 0.32% | 4,000,000 | $10M | $2.47 | — | +4,000,000 | — | NEW |
| 46 | TSM | 0.27% | 27,700 | $8M | $303.89 | $542K | -500 | -1.8% | |
| 47 | ORIC | 0.27% | 1,007,575 | $8M | $8.18 | -$4M | — | — | |
| 48 | MPLT | 0.26% | 450,000 | $8M | $17.57 | — | +450,000 | — | NEW |
| 49 | PVLA | 0.25% | 75,000 | $8M | $104.67 | — | +75,000 | — | NEW |
| 50 | CRWD | 0.25% | 16,500 | $8M | $468.76 | -$1M | -2,000 | -10.8% | |
| 51 | IONQ | 0.25% | 170,000 | $8M | $44.87 | -$3M | — | — | |
| 52 | SEER | 0.24% | 4,000,000 | $7M | $1.83 | -$1M | — | — | |
| 53 | MSFT | 0.24% | 15,000 | $7M | $483.62 | -$2M | -2,150 | -12.5% | |
| 54 | PDD | 0.23% | 63,401 | $7M | $113.39 | $1M | +20,000 | +46.1% | |
| 55 | LXEO | 0.23% | 720,622 | $7M | $9.93 | $3M | +117,187 | +19.4% | |
| 56 | NVDA | 0.23% | 37,485 | $7M | $186.50 | -$3K | — | — | |
| 57 | CRM | 0.22% | 26,100 | $7M | $264.91 | -$220K | -4,000 | -13.3% | |
| 58 | CMPS | 0.22% | 1,000,000 | $7M | $6.90 | — | +1,000,000 | — | NEW |
| 59 | BLLN | 0.22% | 83,833 | $7M | $81.84 | — | +83,833 | — | NEW |
| 60 | WK | 0.22% | 79,123 | $7M | $86.25 | $4M | +49,123 | +163.7% | |
| 61 | GOOGL | 0.21% | 20,703 | $6M | $313.00 | $1M | -500 | -2.4% | |
| 62 | YNDX | 0.21% | 76,218 | $6M | $83.71 | -$2M | +3,618 | +5.0% | |
| 63 | SVRA | 0.20% | 1,000,000 | $6M | $6.03 | — | +1,000,000 | — | NEW |
| 64 | XFOR | 0.19% | 1,500,000 | $6M | $4.00 | — | +1,500,000 | — | NEW |
| 65 | FROG | 0.19% | 93,616 | $6M | $62.46 | $777K | -13,500 | -12.6% | |
| 66 | NOW | 0.18% | 35,630 | $5M | $153.19 | -$1M | +28,504 | +400.0% | |
| 67 | WHWK | 0.16% | 2,082,000 | $5M | $2.42 | $1M | — | — | |
| 68 | DT | 0.16% | 115,229 | $5M | $43.34 | $138K | +15,000 | +15.0% | |
| 69 | DDOG | 0.16% | 36,425 | $5M | $135.99 | $265K | +3,500 | +10.6% | |
| 70 | ALMS | 0.16% | 500,000 | $5M | $9.76 | — | +500,000 | — | NEW |
| 71 | META | 0.15% | 7,169 | $5M | $660.09 | — | +7,169 | — | NEW |
| 72 | PEPG | 0.15% | 700,000 | $5M | $6.51 | $1M | — | — | |
| 73 | SGMT | 0.14% | 724,771 | $4M | $5.92 | -$681K | — | — | |
| 74 | ADBE | 0.14% | 12,051 | $4M | $349.99 | -$1M | -3,000 | -19.9% | |
| 75 | FHTX | 0.13% | 720,720 | $4M | $5.40 | $368K | — | — | |
| 76 | GTLB | 0.12% | 99,000 | $4M | $37.53 | $830K | +35,000 | +54.7% | |
| 77 | KLRS | 0.12% | 435,798 | $4M | $8.44 | $2M | +117,534 | +36.9% | |
| 78 | EDU | 0.11% | 62,000 | $3M | $55.03 | $122K | — | — | |
| 79 | AGEN | 0.11% | 1,064,250 | $3M | $3.14 | -$756K | — | — | |
| 80 | MDLN | 0.10% | 75,000 | $3M | $42.00 | — | +75,000 | — | NEW |
| 81 | KRRO | 0.09% | 347,718 | $3M | $8.01 | -$17M | -71,115 | -17.0% | |
| 82 | CLBT | 0.09% | 150,000 | $3M | $18.04 | $1M | +60,000 | +66.7% | |
| 83 | RANI | 0.09% | 2,000,000 | $3M | $1.35 | — | +2,000,000 | — | NEW |
| 84 | ZS | 0.09% | 12,000 | $3M | $224.92 | — | +12,000 | — | NEW |
| 85 | BDTX | 0.08% | 1,046,517 | $3M | $2.43 | -$1M | — | — | |
| 86 | MNDY | 0.08% | 17,000 | $3M | $147.56 | $1M | +10,000 | +142.9% | |
| 87 | AVGO | 0.08% | 7,000 | $2M | $346.10 | — | +7,000 | — | NEW |
| 88 | QCOM | 0.08% | 14,000 | $2M | $171.05 | $66K | — | — | |
| 89 | ARM | 0.08% | 21,500 | $2M | $109.31 | — | +21,500 | — | NEW |
| 90 | BEKE | 0.07% | 145,000 | $2M | $15.76 | -$470K | — | — | |
| 91 | PANW | 0.07% | 11,450 | $2M | $184.20 | -$630K | -2,000 | -14.9% | |
| 92 | CRWV | 0.06% | 27,500 | $2M | $71.61 | -$1M | +3,500 | +14.6% | |
| 93 | IREN | 0.05% | 43,100 | $2M | $37.77 | $690K | +23,100 | +115.5% | |
| 94 | VRNS | 0.04% | 37,500 | $1M | $32.80 | — | +37,500 | — | NEW |
| 95 | PRMB | 0.04% | 75,000 | $1M | $16.35 | -$431K | — | — | |
| 96 | GBIO | 0.04% | 201,419 | $1M | $5.68 | -$673K | -95,473 | -32.2% | |
| 97 | FIG | 0.03% | 25,000 | $934K | $37.37 | $156K | +10,000 | +66.7% | |
| 98 | TSLA | 0.02% | 1,500 | $675K | $449.72 | $8K | — | — | |
| 99 | CRBU | 0.01% | 105,347 | $168K | $1.59 | -$78K | — | — | |
| 100 | PRQR | —% | — | — | — | -$3M | -1,552,183 | -100.0% | SOLD |