Asset Manager
← All Institutions
Siren, L.L.C.
Market Value
$3.4B
+10.9%
Holdings
117
-6
New Purchases
18
Added To
32
Closed
26
Reduced
18
Top 10 Concentration
52.6%
Turnover
37.6%
Top Buys (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| ERAS | 5.33% | 1.06% | +4.27% | $182M |
| MANE | 2.78% | 0.00% | +2.78% | $95M |
| CYTK | 1.18% | 0.00% | +1.18% | $40M |
| TNGX | 3.46% | 2.35% | +1.12% | $118M |
| XENE | 2.24% | 1.18% | +1.06% | $77M |
| ELVN | 0.86% | 0.00% | +0.86% | $29M |
| ORIC | 1.11% | 0.27% | +0.84% | $38M |
| PVLA | 0.94% | 0.25% | +0.68% | $32M |
| DMRA | 0.68% | 0.00% | +0.68% | $23M |
| ANNX | 0.64% | 0.00% | +0.64% | $22M |
| LXRX | 2.02% | 1.45% | +0.57% | $69M |
| BCAX | 3.38% | 2.85% | +0.53% | $115M |
| DFTX | 0.51% | 0.00% | +0.51% | $17M |
| AMLX | 0.50% | 0.00% | +0.50% | $17M |
| QURE | 0.48% | 0.00% | +0.48% | $16M |
Top Sells (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| APLS | 0.00% | 2.10% | -2.10% | $0 |
| CNTA | 1.23% | 3.27% | -2.04% | $42M |
| RAPT | 0.00% | 1.51% | -1.51% | $0 |
| DYN | 1.18% | 2.22% | -1.04% | $40M |
| ONC | 4.04% | 4.93% | -0.89% | $138M |
| WVE | 0.52% | 1.35% | -0.83% | $18M |
| MLYS | 0.00% | 0.82% | -0.82% | $0 |
| IRON | 1.85% | 2.55% | -0.70% | $63M |
| TSHA | 1.16% | 1.81% | -0.65% | $39M |
| OLMA | 2.08% | 2.68% | -0.60% | $71M |
| TBLA | 0.90% | 1.49% | -0.59% | $31M |
| IHS | 0.00% | 0.57% | -0.57% | $0 |
| GPCR | 1.87% | 2.44% | -0.56% | $64M |
| KYMR | 7.77% | 8.30% | -0.53% | $265M |
| UPB | 0.00% | 0.52% | -0.52% | $0 |
Sector Allocation Over Time
Market Cap Concentration
| Tier | Holdings | Value | Weight |
|---|---|---|---|
| Mega Cap | 11 | $88M | 2.6% |
| Large Cap | 21 | $411M | 12.0% |
| Mid Cap | 34 | $2.1B | 61.6% |
| Small Cap | 34 | $756M | 22.1% |
| Micro Cap | 17 | $57M | 1.7% |
Portfolio Analytics
Avg Market Cap
$221.7B
Median Market Cap
$2.7B
Avg P/E
70.1
Median P/E
35.0
Avg Dividend Yield
0.00%
Avg Beta
1.22
# Stocks
117
# ETFs / Funds
0
Top Holdings (117 total)
| # | Symbol | % Port | Shares | Value | Avg Price | Q/Q Value Chg | Share Chg | Chg % | Status |
|---|---|---|---|---|---|---|---|---|---|
| 1 | SRRK | 15.58% | 10,825,013 | $532M | $49.16 | $55M | — | — | |
| 2 | KYMR | 7.77% | 3,186,830 | $265M | $83.29 | $10M | -100,000 | -3.0% | |
| 3 | ERAS | 5.33% | 11,244,246 | $182M | $16.18 | $149M | +2,486,997 | +28.4% | |
| 4 | EWTX | 4.09% | 4,430,263 | $140M | $31.50 | $27M | -99,727 | -2.2% | |
| 5 | ONC | 4.04% | 465,000 | $138M | $296.97 | -$14M | -35,000 | -7.0% | |
| 6 | TNGX | 3.46% | 5,657,105 | $118M | $20.92 | $46M | -2,508,269 | -30.7% | |
| 7 | BCAX | 3.38% | 5,802,970 | $115M | $19.89 | $28M | +586,001 | +11.2% | |
| 8 | RVMD | 3.16% | 1,110,980 | $108M | $97.25 | $2M | -224,095 | -16.8% | |
| 9 | ARWR | 2.97% | 1,615,476 | $101M | $62.70 | $2M | +115,000 | +7.7% | |
| 10 | MANE | 2.78% | 1,505,374 | $95M | $63.15 | — | +1,505,374 | — | NEW |
| 11 | XENE | 2.24% | 1,318,564 | $77M | $58.15 | $40M | +505,803 | +62.2% | |
| 12 | OLMA | 2.08% | 4,756,949 | $71M | $14.91 | -$12M | +1,456,249 | +44.1% | |
| 13 | CRNX | 2.02% | 1,903,636 | $69M | $36.32 | -$1M | +396,000 | +26.3% | |
| 14 | LXRX | 2.02% | 44,303,518 | $69M | $1.56 | $24M | +5,384,615 | +13.8% | |
| 15 | COGT | 1.93% | 1,709,279 | $66M | $38.49 | $8M | +80,000 | +4.9% | |
| 16 | STOK | 1.90% | 1,995,347 | $65M | $32.56 | -$6M | -252,000 | -11.2% | |
| 17 | RCUS | 1.90% | 3,007,077 | $65M | $21.60 | -$7M | — | — | |
| 18 | GPCR | 1.87% | 1,328,698 | $64M | $48.20 | -$11M | +250,000 | +23.2% | |
| 19 | IRON | 1.85% | 988,401 | $63M | $63.94 | -$15M | — | — | |
| 20 | RYTM | 1.85% | 725,511 | $63M | $86.97 | $10M | +225,536 | +45.1% | |
| 21 | SEPN | 1.41% | 2,000,000 | $48M | $24.03 | -$8M | — | — | |
| 22 | CNTA | 1.23% | 1,053,464 | $42M | $39.72 | -$59M | -2,974,053 | -73.8% | |
| 23 | SYRE | 1.21% | 818,598 | $41M | $50.44 | $14M | — | — | |
| 24 | CYTK | 1.18% | 613,952 | $40M | $65.91 | — | +613,952 | — | NEW |
| 25 | DYN | 1.18% | 2,229,125 | $40M | $18.13 | -$28M | -1,273,816 | -36.4% | |
| 26 | TSHA | 1.16% | 8,829,913 | $39M | $4.47 | -$16M | -1,300,000 | -12.8% | |
| 27 | ORIC | 1.11% | 2,998,192 | $38M | $12.67 | $30M | +1,990,617 | +197.6% | |
| 28 | PVLA | 0.94% | 257,485 | $32M | $124.65 | $24M | +182,485 | +243.3% | |
| 29 | TBLA | 0.90% | 9,969,495 | $31M | $3.10 | -$15M | — | — | |
| 30 | ELVN | 0.86% | 746,226 | $29M | $39.20 | — | +746,226 | — | NEW |
| 31 | DNLI | 0.79% | 1,396,513 | $27M | $19.20 | $4M | — | — | |
| 32 | RELY | 0.71% | 1,543,271 | $24M | $15.67 | $2M | -75,000 | -4.6% | |
| 33 | DMRA | 0.68% | 900,000 | $23M | $25.90 | — | +900,000 | — | NEW |
| 34 | ANNX | 0.64% | 3,958,646 | $22M | $5.54 | — | +3,958,646 | — | NEW |
| 35 | TRVI | 0.62% | 1,786,867 | $21M | $11.93 | -$7M | -500,000 | -21.9% | |
| 36 | RAPP | 0.59% | 641,469 | $20M | $31.29 | -$1M | -67,000 | -9.5% | |
| 37 | GOOGL | 0.55% | 65,703 | $19M | $287.56 | $12M | +45,000 | +217.4% | |
| 38 | FULC | 0.53% | 2,350,000 | $18M | $7.67 | -$4M | +400,000 | +20.5% | |
| 39 | WVE | 0.52% | 2,450,000 | $18M | $7.25 | -$24M | — | — | |
| 40 | DFTX | 0.51% | 919,493 | $17M | $18.90 | — | +919,493 | — | NEW |
| 41 | AMLX | 0.50% | 1,230,000 | $17M | $13.90 | — | +1,230,000 | — | NEW |
| 42 | CGEM | 0.50% | 1,193,410 | $17M | $14.21 | $5M | — | — | |
| 43 | NMRA | 0.49% | 8,497,822 | $17M | $1.95 | $5M | +2,209,039 | +35.1% | |
| 44 | QURE | 0.48% | 1,000,000 | $16M | $16.35 | — | +1,000,000 | — | NEW |
| 45 | CTMX | 0.48% | 3,457,711 | $16M | $4.70 | — | +3,457,711 | — | NEW |
| 46 | NVDA | 0.45% | 89,085 | $16M | $174.40 | $9M | +51,600 | +137.7% | |
| 47 | SLN | 0.45% | 2,911,438 | $15M | $5.27 | -$2M | — | — | |
| 48 | MSFT | 0.45% | 41,380 | $15M | $370.17 | $8M | +26,380 | +175.9% | |
| 49 | TSM | 0.42% | 42,200 | $14M | $337.95 | $6M | +14,500 | +52.4% | |
| 50 | SION | 0.35% | 300,000 | $12M | $40.09 | -$315K | — | — | |
| 51 | YNDX | 0.35% | 113,614 | $12M | $103.76 | $5M | +37,396 | +49.1% | |
| 52 | RZLT | 0.30% | 3,328,287 | $10M | $3.05 | — | +3,328,287 | — | NEW |
| 53 | AMZN | 0.28% | 46,641 | $10M | $208.27 | -$2M | -4,859 | -9.4% | |
| 54 | GENB | 0.27% | 736,104 | $9M | $12.50 | — | +736,104 | — | NEW |
| 55 | MPLT | 0.27% | 450,000 | $9M | $20.33 | $1M | — | — | |
| 56 | NOW | 0.27% | 87,090 | $9M | $104.55 | $4M | +51,460 | +144.4% | |
| 57 | CRWD | 0.26% | 23,070 | $9M | $390.41 | $1M | +6,570 | +39.8% | |
| 58 | PDD | 0.25% | 83,401 | $9M | $102.18 | $1M | +20,000 | +31.6% | |
| 59 | TSLA | 0.23% | 21,500 | $8M | $371.75 | $7M | +20,000 | +1333.3% | |
| 60 | IMAB | 0.22% | 3,000,000 | $7M | $2.46 | -$5M | — | — | |
| 61 | BCYC | 0.21% | 1,560,882 | $7M | $4.64 | -$7M | -451,870 | -22.4% | |
| 62 | WHWK | 0.21% | 2,082,000 | $7M | $3.45 | $2M | — | — | |
| 63 | DDOG | 0.19% | 54,300 | $6M | $118.05 | $1M | +17,875 | +49.1% | |
| 64 | FROG | 0.18% | 128,816 | $6M | $46.93 | $198K | +35,200 | +37.6% | |
| 65 | DT | 0.16% | 150,000 | $6M | $36.98 | $553K | +34,771 | +30.2% | |
| 66 | WK | 0.16% | 92,500 | $6M | $59.63 | -$1M | +13,377 | +16.9% | |
| 67 | ABSI | 0.16% | 1,800,000 | $5M | $3.00 | — | +1,800,000 | — | NEW |
| 68 | ADGI | 0.15% | 4,000,000 | $5M | $1.30 | -$5M | — | — | |
| 69 | MSLE | 0.15% | 892,074 | $5M | $5.63 | — | +892,074 | — | NEW |
| 70 | IONQ | 0.14% | 170,000 | $5M | $28.83 | -$3M | — | — | |
| 71 | AVGO | 0.14% | 15,000 | $5M | $309.51 | $2M | +8,000 | +114.3% | |
| 72 | AGMB | 0.13% | 411,250 | $4M | $10.49 | — | +411,250 | — | NEW |
| 73 | CLBT | 0.13% | 311,544 | $4M | $13.78 | $2M | +161,544 | +107.7% | |
| 74 | SEER | 0.12% | 2,458,673 | $4M | $1.68 | -$3M | -1,541,327 | -38.5% | |
| 75 | KRRO | 0.12% | 347,718 | $4M | $11.32 | $1M | — | — | |
| 76 | AGEN | 0.10% | 1,064,250 | $4M | $3.34 | $213K | — | — | |
| 77 | FHTX | 0.10% | 720,720 | $3M | $4.78 | -$447K | — | — | |
| 78 | FPS | 0.09% | 100,000 | $3M | $29.27 | — | +100,000 | — | NEW |
| 79 | KLRS | 0.07% | 435,798 | $3M | $5.77 | -$1M | — | — | |
| 80 | GTLB | 0.06% | 100,000 | $2M | $21.64 | -$2M | +1,000 | +1.0% | |
| 81 | MU | 0.06% | 6,000 | $2M | $337.84 | — | +6,000 | — | NEW |
| 82 | MNDY | 0.05% | 25,000 | $2M | $69.11 | -$781K | +8,000 | +47.1% | |
| 83 | GOSS | 0.05% | 5,208,968 | $2M | $0.33 | -$14M | — | — | |
| 84 | BEKE | 0.04% | 100,000 | $1M | $14.97 | -$788K | -45,000 | -31.0% | |
| 85 | IREN | 0.04% | 43,100 | $1M | $34.28 | -$150K | — | — | |
| 86 | RANI | 0.04% | 2,000,000 | $1M | $0.73 | -$1M | — | — | |
| 87 | AEVA | 0.04% | 110,000 | $1M | $13.16 | — | +110,000 | — | NEW |
| 88 | MDLN | 0.03% | 25,000 | $1M | $44.50 | -$2M | -50,000 | -66.7% | |
| 89 | FIG | 0.03% | 50,000 | $1M | $21.14 | $123K | +25,000 | +100.0% | |
| 90 | PRMB | 0.03% | 50,000 | $942K | $18.83 | -$285K | -25,000 | -33.3% | |
| 91 | NU | 0.01% | 25,000 | $359K | $14.37 | — | +25,000 | — | NEW |
| 92 | MLYS | —% | — | — | — | -$25M | -699,999 | -100.0% | SOLD |
| 93 | CRBU | —% | — | — | — | -$168K | -105,347 | -100.0% | SOLD |
| 94 | QCOM | —% | — | — | — | -$2M | -14,000 | -100.0% | SOLD |
| 95 | PANW | —% | — | — | — | -$2M | -11,450 | -100.0% | SOLD |
| 96 | VRNS | —% | — | — | — | -$1M | -37,500 | -100.0% | SOLD |
| 97 | PEPG | —% | — | — | — | -$5M | -700,000 | -100.0% | SOLD |
| 98 | LXEO | —% | — | — | — | -$7M | -720,622 | -100.0% | SOLD |
| 99 | ZS | —% | — | — | — | -$3M | -12,000 | -100.0% | SOLD |
| 100 | UPB | —% | — | — | — | -$16M | -588,450 | -100.0% | SOLD |