SPRO Institutional Ownership
Spero Therapeutics, Inc.
1W: -3.2%
1M: -2.5%
3M: -45.7%
YTD: -49.4%
1Y: -39.3%
3Y: -0.8%
5Y: -93.7%
$1.19
-0.07 (-5.56%)
Weekly Expected Move ±11.7%
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Institutional Ownership — SPRO
73
Institutional Holders
+11 vs prior quarter
0.0%
Ownership
+0.00pp
$48M
Total Invested
23
New Positions
16
Increased
18
Reduced
12
Closed
1.00
Put/Call Ratio
Ownership Trends
Top Institutional Holders (82 total)
| # | Holder | Shares | Value | Change | Change % | Holding Period | Filing |
|---|---|---|---|---|---|---|---|
| 1 | GSK plc | 9,190,606 | $$11M | — | +0.0% | 3Q | SEC ↗ |
| 2 | Pfizer Inc | 2,362,348 | $$3M | — | +0.0% | 7Q | SEC ↗ |
| 3 | VANGUARD CAPITAL MANAGEMENT LLC | 2,036,226 | $$2M | +236,346 | +13.1% | 2Q | SEC ↗ |
| 4 | RENAISSANCE TECHNOLOGIES LLC | 947,904 | $$1M | -241,331 | -20.3% | 18Q | SEC ↗ |
| 5 | Alphabet Inc. | 889,979 | $$1M | — | +0.0% | 35Q | SEC ↗ |
| 6 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 759,290 | $$904K | +426,175 | +127.9% | 3Q | SEC ↗ |
| 7 | BlackRock, Inc. | 594,404 | $$707K | +161,202 | +37.2% | 8Q | SEC ↗ |
| 8 | GEODE CAPITAL MANAGEMENT, LLC | 566,329 | $$674K | +46,407 | +8.9% | 34Q | SEC ↗ |
| 9 | RAYMOND JAMES FINANCIAL INC NEW | 521,705 | $$621K | — | +0.0% | 1Q | SEC ↗ |
| 10 | TWO SIGMA INVESTMENTS, LP | 382,814 | $$456K | -502,817 | -56.8% | 4Q | SEC ↗ |
| 11 | ARROWSTREET CAPITAL, LIMITED PARTNERSH NEW | 332,970 | $$396K | — | +0.0% | 1Q | SEC ↗ |
| 12 | VANGUARD FIDUCIARY TRUST CO | 287,648 | $$342K | +23,533 | +8.9% | 2Q | SEC ↗ |
| 13 | GSA CAPITAL PARTNERS LLP | 285,906 | $$340K | +7,602 | +2.7% | 4Q | SEC ↗ |
| 14 | DIMENSIONAL FUND ADVISORS LP | 274,820 | $$327K | +245,052 | +823.2% | 4Q | SEC ↗ |
| 15 | GOLDMAN SACHS GROUP INC NEW | 256,985 | $$306K | — | +0.0% | 1Q | SEC ↗ |
| 16 | STATE STREET CORP | 214,751 | $$256K | — | +0.0% | 34Q | SEC ↗ |
| 17 | JANE STREET GROUP, LLC | 158,097 | $$188K | +51,752 | +48.7% | 4Q | SEC ↗ |
| 18 | UBS Group AG | 139,680 | $$166K | +136,671 | +4542.1% | 29Q | SEC ↗ |
| 19 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 114,800 | $$137K | — | +0.0% | 14Q | SEC ↗ |
| 20 | NORTHERN TRUST CORP | 108,274 | $$129K | -12,710 | -10.5% | 35Q | SEC ↗ |
| 21 | Point72 Asset Management, L.P. | 104,377 | $$124K | +44,709 | +74.9% | 3Q | SEC ↗ |
| 22 | Ionic Capital Management LLC | 102,698 | $$122K | -93,241 | -47.6% | 5Q | SEC ↗ |
| 23 | Federation des caisses Desjardins du Q NEW | 91,900 | $$109K | — | +0.0% | 1Q | SEC ↗ |
| 24 | Shay Capital LLC | 72,391 | $$86K | +2,037 | +2.9% | 4Q | SEC ↗ |
| 25 | Invesco Ltd. | 64,245 | $$76K | +18,871 | +41.6% | 5Q | SEC ↗ |
| 26 | SIMPLEX TRADING, LLC | 61,312 | $$73K | +31,008 | +102.3% | 8Q | SEC ↗ |
| 27 | Verdad Advisers, LP | 51,335 | $$61K | +17,880 | +53.4% | 2Q | SEC ↗ |
| 28 | XTX Topco Ltd NEW | 50,536 | $$60K | — | +0.0% | 1Q | SEC ↗ |
| 29 | AMERICAN CENTURY COMPANIES INC NEW | 36,811 | $$44K | — | +0.0% | 1Q | SEC ↗ |
| 30 | Capital Asset Advisory Services LLC | 32,548 | $$39K | — | +0.0% | 5Q | SEC ↗ |
| 31 | AXXCESS WEALTH MANAGEMENT, LLC NEW | 32,548 | $$39K | — | +0.0% | 1Q | SEC ↗ |
| 32 | DLK Investment Management, LLC NEW | 31,355 | $$37K | — | +0.0% | 1Q | SEC ↗ |
| 33 | Three Seasons Wealth, LLC | 30,000 | $$36K | — | +0.0% | 11Q | SEC ↗ |
| 34 | Sixth Street Partners Management Compa NEW | 28,565 | $$34K | — | +0.0% | 1Q | SEC ↗ |
| 35 | CHARLES SCHWAB INVESTMENT MANAGEMENT I | 28,565 | $$34K | — | +0.0% | 15Q | SEC ↗ |
| 36 | Vanguard Global Advisers, LLC | 25,446 | $$30K | — | +0.0% | 2Q | SEC ↗ |
| 37 | Global Retirement Partners, LLC NEW | 25,000 | $$30K | — | +0.0% | 1Q | SEC ↗ |
| 38 | OPPENHEIMER & CO INC NEW | 22,850 | $$27K | — | +0.0% | 1Q | SEC ↗ |
| 39 | MILLENNIUM MANAGEMENT LLC NEW | 19,298 | $$23K | — | +0.0% | 1Q | SEC ↗ |
| 40 | Assenagon Asset Management S.A. | 18,636 | $$22K | — | +0.0% | 4Q | SEC ↗ |
| 41 | Susquehanna Portfolio Strategies, LLC NEW | 17,628 | $$21K | — | +0.0% | 1Q | SEC ↗ |
| 42 | SUSQUEHANNA FUNDAMENTAL INVESTMENTS, L NEW | 16,095 | $$19K | — | +0.0% | 1Q | SEC ↗ |
| 43 | Qube Research & Technologies Ltd NEW | 13,644 | $$16K | — | +0.0% | 1Q | SEC ↗ |
| 44 | SG Americas Securities, LLC NEW | 11,268 | $$13K | — | +0.0% | 1Q | SEC ↗ |
| 45 | GROUP ONE TRADING LLC NEW | 10,869 | $$13K | — | +0.0% | 1Q | SEC ↗ |
| 46 | TWO SIGMA SECURITIES, LLC NEW | 10,576 | $$13K | — | +0.0% | 1Q | SEC ↗ |
| 47 | PRUDENTIAL FINANCIAL INC NEW | 10,400 | $$12K | — | +0.0% | 1Q | SEC ↗ |
| 48 | CITIGROUP INC | 9,625 | $$11K | -9,510 | -49.7% | 3Q | SEC ↗ |
| 49 | FNY Investment Advisers, LLC | 8,300 | $$10K | +3,000 | +56.6% | 4Q | SEC ↗ |
| 50 | JONES FINANCIAL COMPANIES LLLP | 7,678 | $$9K | — | +0.0% | 3Q | SEC ↗ |
Recent Activity
New Positions (20)
| Holder | Shares | Value |
|---|---|---|
| RAYMOND JAMES FINANCIAL INC | 521,705 | $$621K |
| ARROWSTREET CAPITAL, LIMITED PARTNE | 332,970 | $$396K |
| GOLDMAN SACHS GROUP INC | 256,985 | $$306K |
| Federation des caisses Desjardins d | 91,900 | $$109K |
| XTX Topco Ltd | 50,536 | $$60K |
| AMERICAN CENTURY COMPANIES INC | 36,811 | $$44K |
| AXXCESS WEALTH MANAGEMENT, LLC | 32,548 | $$39K |
| DLK Investment Management, LLC | 31,355 | $$37K |
| Sixth Street Partners Management Co | 28,565 | $$34K |
| Global Retirement Partners, LLC | 25,000 | $$30K |
| OPPENHEIMER & CO INC | 22,850 | $$27K |
| MILLENNIUM MANAGEMENT LLC | 19,298 | $$23K |
| Susquehanna Portfolio Strategies, L | 17,628 | $$21K |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS | 16,095 | $$19K |
| Qube Research & Technologies Ltd | 13,644 | $$16K |
| SG Americas Securities, LLC | 11,268 | $$13K |
| GROUP ONE TRADING LLC | 10,869 | $$13K |
| TWO SIGMA SECURITIES, LLC | 10,576 | $$13K |
| PRUDENTIAL FINANCIAL INC | 10,400 | $$12K |
| Integrated Wealth Concepts LLC | 6,000 | $$7K |
Sold Out (20)
| Holder | Prev Shares | Prev Value |
|---|---|---|
| Anson Funds Management LP | 421,956 | $$502K |
| CITADEL ADVISORS LLC | 376,458 | $$448K |
| Informed Momentum Co LLC | 218,084 | $$260K |
| Squarepoint Ops LLC | 194,301 | $$231K |
| MARSHALL WACE, LLP | 157,072 | $$187K |
| SEI INVESTMENTS CO | 132,009 | $$157K |
| ADAR1 Capital Management, LLC | 113,839 | $$135K |
| Quadrature Capital Ltd | 40,128 | $$48K |
| OMERS ADMINISTRATION Corp | 39,400 | $$47K |
| Schonfeld Strategic Advisors LLC | 20,314 | $$24K |
| Torrey Growth & Income Advisors | 17,025 | $$20K |
| OCCUDO QUANTITATIVE STRATEGIES LP | 16,421 | $$20K |
| INTREPID FAMILY OFFICE LLC | 16,279 | $$19K |
| Texas Yale Capital Corp. | 10,000 | $$12K |
| Tower Research Capital LLC (TRC) | 7,215 | $$9K |
| Cullen/Frost Bankers, Inc. | 3,000 | $$4K |
| BANK OF AMERICA CORP /DE | 744 | $$1K |
| Rockefeller Capital Management L.P. | 200 | $$0K |
| BNP PARIBAS FINANCIAL MARKETS | 40 | $$0K |
| SageView Advisory Group, LLC | 17 | $$0K |
Biggest Increases (16)
| Holder | Added | Change % | Total Shares |
|---|---|---|---|
| SUSQUEHANNA INTERNATIONAL GROUP, LL | +426,175 | +127.9% | 759,290 |
| DIMENSIONAL FUND ADVISORS LP | +245,052 | +823.2% | 274,820 |
| VANGUARD CAPITAL MANAGEMENT LLC | +236,346 | +13.1% | 2,036,226 |
| BlackRock, Inc. | +161,202 | +37.2% | 594,404 |
| UBS Group AG | +136,671 | +4542.1% | 139,680 |
| JANE STREET GROUP, LLC | +51,752 | +48.7% | 158,097 |
| GEODE CAPITAL MANAGEMENT, LLC | +46,407 | +8.9% | 566,329 |
| Point72 Asset Management, L.P. | +44,709 | +74.9% | 104,377 |
| SIMPLEX TRADING, LLC | +31,008 | +102.3% | 61,312 |
| VANGUARD FIDUCIARY TRUST CO | +23,533 | +8.9% | 287,648 |
| Invesco Ltd. | +18,871 | +41.6% | 64,245 |
| Verdad Advisers, LP | +17,880 | +53.4% | 51,335 |
| GSA CAPITAL PARTNERS LLP | +7,602 | +2.7% | 285,906 |
| FNY Investment Advisers, LLC | +3,000 | +56.6% | 8,300 |
| Shay Capital LLC | +2,037 | +2.9% | 72,391 |
| SBI Securities Co., Ltd. | +4 | +44.4% | 13 |
Biggest Decreases (6)
| Holder | Reduced | Change % | Total Shares |
|---|---|---|---|
| TWO SIGMA INVESTMENTS, LP | -502,817 | -56.8% | 382,814 |
| RENAISSANCE TECHNOLOGIES LLC | -241,331 | -20.3% | 947,904 |
| Ionic Capital Management LLC | -93,241 | -47.6% | 102,698 |
| NORTHERN TRUST CORP | -12,710 | -10.5% | 108,274 |
| CITIGROUP INC | -9,510 | -49.7% | 9,625 |
| MORGAN STANLEY | -3,638 | -79.9% | 914 |