TPST NASDAQ
Brisbane, CA 94080
US
Tempest Therapeutics Inc., a clinical-stage oncology company, engages in developing small molecule therapeutics to treat cancer. The company's two clinical programs are TPST-1495, a dual antagonist of EP2 and EP4, receptors of prostaglandin E2, and is currently in a Phase 1 trial in solid tumors; and TPST-1120, a selective antagonist of peroxisome proliferator-activated receptor alpha that is in a Phase 1 trial in solid tumors. It also develops TREX-1, a key cellular enzyme that regulates the innate immune response in tumors. The company was founded in 2011 and is headquartered in South San Francisco, California. Tempest Therapeutics Inc. was formerly a subsidiary of Inception Sciences, Inc.
Recent Insider Trades
| Name | Type | Shares | Price | Date |
|---|---|---|---|---|
| Trojanowski Justin | A-Award | 22,000 | $1.64 | 2026-03-31 |
| Maestas Nicholas | A-Award | 140,000 | $1.64 | 2026-03-31 |
| Angel Matthew | P-Purchase | 231,482 | $2.16 | 2026-03-24 |
| Angel Matthew | A-Award | 269,621 | $2.38 | 2026-02-04 |
| Angel Matthew | 0 | — | 2026-02-03 |