Asset Manager
← All Institutions
ORBIMED ADVISORS LLC
Market Value
$4.1B
+3.1%
Holdings
103
-4
New Purchases
15
Added To
11
Closed
14
Reduced
22
Top 10 Concentration
42.4%
Turnover
28.2%
Top Buys (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| DHR | 1.29% | 0.00% | +1.29% | $52M |
| UTHR | 1.19% | 0.00% | +1.19% | $48M |
| CI | 1.16% | 0.00% | +1.16% | $47M |
| MLYS | 1.37% | 0.26% | +1.11% | $56M |
| SION | 2.68% | 1.63% | +1.05% | $109M |
| UPB | 2.64% | 1.59% | +1.05% | $107M |
| EWTX | 6.20% | 5.17% | +1.03% | $252M |
| ORIC | 1.08% | 0.23% | +0.84% | $44M |
| ABVX | 0.79% | 0.00% | +0.79% | $32M |
| TERN | 1.40% | 0.72% | +0.68% | $57M |
| APLS | 1.30% | 0.65% | +0.64% | $53M |
| EYPT | 0.63% | 0.00% | +0.63% | $26M |
| CRVS | 1.30% | 0.73% | +0.57% | $53M |
| MBX | 1.73% | 1.16% | +0.57% | $70M |
| ALNY | 3.39% | 2.83% | +0.56% | $138M |
Top Sells (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| SVA | 4.54% | 8.49% | -3.94% | $184M |
| UNH | 0.00% | 2.67% | -2.67% | $0 |
| VRTX | 0.00% | 2.38% | -2.38% | $0 |
| THC | 0.00% | 2.08% | -2.08% | $0 |
| BSX | 5.84% | 7.68% | -1.83% | $237M |
| SBTX | 2.05% | 3.67% | -1.62% | $83M |
| LLY | 5.66% | 6.69% | -1.02% | $230M |
| CYTK | 0.00% | 0.90% | -0.90% | $0 |
| ISRG | 3.16% | 4.02% | -0.85% | $128M |
| NTRA | 1.70% | 2.55% | -0.84% | $69M |
| THRD | 0.00% | 0.80% | -0.80% | $0 |
| ITGR | 0.74% | 1.35% | -0.62% | $30M |
| AGIO | 0.00% | 0.47% | -0.47% | $0 |
| SYK | 3.27% | 3.61% | -0.34% | $133M |
| XENE | 0.42% | 0.75% | -0.34% | $17M |
Sector Allocation Over Time
Market Cap Concentration
| Tier | Holdings | Value | Weight |
|---|---|---|---|
| Mega Cap | 3 | $252M | 6.2% |
| Large Cap | 18 | $1.3B | 32.9% |
| Mid Cap | 27 | $1.2B | 30.4% |
| Small Cap | 30 | $809M | 19.9% |
| Micro Cap | 25 | $427M | 10.5% |
Portfolio Analytics
Avg Market Cap
$27.4B
Median Market Cap
$1.6B
Avg P/E
29.9
Median P/E
33.3
Avg Dividend Yield
0.00%
Avg Beta
0.86
# Stocks
103
# ETFs / Funds
0
Top Holdings (103 total)
| # | Symbol | % Port | Shares | Value | Avg Price | Q/Q Value Chg | Share Chg | Chg % | Status |
|---|---|---|---|---|---|---|---|---|---|
| 1 | EWTX | 6.20% | 15,518,492 | $252M | $16.22 | $48M | — | — | |
| 2 | BSX | 5.84% | 2,429,300 | $237M | $97.63 | -$65M | -383,900 | -13.7% | |
| 3 | LLY | 5.66% | 301,200 | $230M | $763.00 | -$33M | -36,400 | -10.8% | |
| 4 | SVA | 4.54% | 2,718,735 | $184M | $67.85 | -$150M | — | — | |
| 5 | ELVN | 4.01% | 7,959,538 | $163M | $20.47 | $3M | — | — | |
| 6 | ALNY | 3.39% | 301,600 | $138M | $456.00 | $26M | -40,300 | -11.8% | |
| 7 | SYK | 3.27% | 359,200 | $133M | $369.67 | -$9M | — | — | |
| 8 | EW | 3.23% | 1,684,000 | $131M | $77.77 | -$3M | -24,000 | -1.4% | |
| 9 | ISRG | 3.16% | 287,200 | $128M | $447.23 | -$30M | -3,800 | -1.3% | |
| 10 | ARGX | 3.13% | 172,300 | $127M | $737.56 | $12M | -35,700 | -17.2% | |
| 11 | SION | 2.68% | 3,704,959 | $109M | $29.41 | $45M | — | — | |
| 12 | UPB | 2.64% | 5,693,589 | $107M | $18.81 | $45M | — | — | |
| 13 | IRON | 2.30% | 1,415,020 | $94M | $66.08 | $19M | — | — | |
| 14 | CAI | 2.26% | 3,034,858 | $92M | $30.25 | $11M | — | — | |
| 15 | SBTX | 2.05% | 8,288,510 | $83M | $10.05 | -$61M | — | — | |
| 16 | RNAM | 1.76% | 1,638,886 | $71M | $43.57 | $20M | -174,000 | -9.6% | |
| 17 | MBX | 1.73% | 4,002,887 | $70M | $17.50 | $24M | — | — | |
| 18 | CGON | 1.71% | 1,726,850 | $70M | $40.28 | $21M | -151,000 | -8.0% | |
| 19 | NTRA | 1.70% | 429,300 | $69M | $160.97 | -$31M | -164,134 | -27.7% | |
| 20 | AXSM | 1.59% | 531,800 | $65M | $121.45 | $20M | +103,900 | +24.3% | |
| 21 | TERN | 1.40% | 7,562,971 | $57M | $7.51 | $29M | — | — | |
| 22 | AVBP | 1.38% | 3,027,328 | $56M | $18.45 | -$10M | — | — | |
| 23 | MLYS | 1.37% | 1,469,494 | $56M | $37.92 | $45M | +709,143 | +93.3% | |
| 24 | EXAS | 1.34% | 994,616 | $54M | $54.71 | $22M | +387,300 | +63.8% | |
| 25 | CMPX | 1.31% | 15,219,994 | $53M | $3.50 | $14M | — | — | |
| 26 | CRVS | 1.30% | 7,165,006 | $53M | $7.37 | $24M | — | — | |
| 27 | APLS | 1.30% | 2,323,368 | $53M | $22.63 | $27M | +841,068 | +56.7% | |
| 28 | DHR | 1.29% | 263,100 | $52M | $198.26 | — | +263,100 | — | NEW |
| 29 | NBIX | 1.22% | 353,640 | $50M | $140.38 | -$5M | -84,900 | -19.4% | |
| 30 | UTHR | 1.19% | 114,900 | $48M | $419.21 | — | +114,900 | — | NEW |
| 31 | CI | 1.16% | 162,800 | $47M | $288.25 | — | +162,800 | — | NEW |
| 32 | CRNX | 1.13% | 1,099,000 | $46M | $41.65 | $13M | -50,000 | -4.3% | |
| 33 | ORIC | 1.08% | 3,641,756 | $44M | $12.00 | $35M | +2,742,475 | +305.0% | |
| 34 | JANX | 1.06% | 1,766,100 | $43M | $24.44 | $15M | +555,800 | +45.9% | |
| 35 | ROIV | 1.01% | 2,714,798 | $41M | $15.13 | $10M | -64,629 | -2.3% | |
| 36 | SIBN | 0.94% | 2,578,979 | $38M | $14.72 | -$11M | — | — | |
| 37 | SCPH | 0.85% | 6,059,528 | $34M | $5.67 | $11M | — | — | |
| 38 | ABVX | 0.79% | 380,000 | $32M | $84.90 | — | +380,000 | — | NEW |
| 39 | GPCR | 0.79% | 1,139,300 | $32M | $28.00 | $7M | -60,000 | -5.0% | |
| 40 | TRVI | 0.75% | 3,308,400 | $30M | $9.15 | $12M | — | — | |
| 41 | ITGR | 0.74% | 290,000 | $30M | $103.33 | -$23M | -143,400 | -33.1% | |
| 42 | DYN | 0.72% | 2,314,184 | $29M | $12.65 | $19M | +1,282,784 | +124.4% | |
| 43 | RAPT | 0.69% | 1,086,618 | $28M | $25.79 | $15M | -555,288 | -33.8% | |
| 44 | CTMX | 0.67% | 8,461,500 | $27M | $3.19 | $8M | — | — | |
| 45 | NPCE | 0.66% | 2,614,184 | $27M | $10.31 | -$2M | — | — | |
| 46 | EYPT | 0.63% | 1,796,000 | $26M | $14.24 | — | +1,796,000 | — | NEW |
| 47 | AKRO | 0.62% | 526,200 | $25M | $47.48 | $14M | +314,900 | +149.0% | |
| 48 | ADCT | 0.58% | 5,907,351 | $24M | $4.00 | $8M | — | — | |
| 49 | TMO | 0.56% | 46,500 | $23M | $485.02 | $4M | — | — | |
| 50 | RYTM | 0.54% | 215,152 | $22M | $100.99 | $6M | -33,360 | -13.4% | |
| 51 | KRYS | 0.45% | 102,745 | $18M | $176.53 | $17M | +93,545 | +1016.8% | |
| 52 | FBRX | 0.44% | 1,196,955 | $18M | $15.00 | $2M | — | — | |
| 53 | AVTX | 0.42% | 1,349,300 | $17M | $12.71 | $12M | +382,300 | +39.5% | |
| 54 | XENE | 0.42% | 419,600 | $17M | $40.15 | -$13M | -528,277 | -55.7% | |
| 55 | CARL | 0.41% | 1,252,600 | $17M | $13.39 | — | +1,252,600 | — | NEW |
| 56 | KROS | 0.40% | 1,018,734 | $16M | $15.82 | $3M | — | — | |
| 57 | PRLD | 0.39% | 10,909,256 | $16M | $1.44 | $7M | — | — | |
| 58 | STTK | 0.37% | 6,306,127 | $15M | $2.39 | — | +6,306,127 | — | NEW |
| 59 | CRBP | 0.37% | 1,172,287 | $15M | $12.65 | $7M | — | — | |
| 60 | VIR | 0.33% | 2,380,715 | $14M | $5.71 | $2M | — | — | |
| 61 | FOLD | 0.32% | 1,645,400 | $13M | $7.88 | -$130K | -640,000 | -28.0% | |
| 62 | TARS | 0.29% | 197,900 | $12M | $59.43 | $4M | — | — | |
| 63 | CCCC | 0.29% | 5,235,146 | $12M | $2.22 | $2M | -1,595,154 | -23.4% | |
| 64 | CGEM | 0.28% | 1,923,855 | $11M | $5.93 | -$3M | — | — | |
| 65 | VTGN | 0.27% | 3,060,000 | $11M | $3.55 | — | +3,060,000 | — | NEW |
| 66 | AMLX | 0.25% | 750,600 | $10M | $13.59 | $8M | +437,400 | +139.7% | |
| 67 | PMVP | 0.21% | 5,975,291 | $8M | $1.40 | $2M | -500,000 | -7.7% | |
| 68 | WHWK | 0.20% | 4,166,000 | $8M | $1.90 | $125K | — | — | |
| 69 | VSTM | 0.19% | 887,561 | $8M | $8.83 | — | +887,561 | — | NEW |
| 70 | BTSG | 0.19% | 263,800 | $8M | $29.56 | — | +263,800 | — | NEW |
| 71 | ALMS | 0.19% | 1,926,423 | $8M | $3.99 | $2M | — | — | |
| 72 | BCRX | 0.17% | 901,500 | $7M | $7.59 | — | +901,500 | — | NEW |
| 73 | MIST | 0.16% | 3,221,828 | $6M | $2.00 | — | +3,221,828 | — | NEW |
| 74 | RPTX | 0.14% | 3,322,488 | $6M | $1.76 | $1M | — | — | |
| 75 | NSPR | 0.13% | 2,133,405 | $5M | $2.41 | $299K | — | — | |
| 76 | BIOA | 0.11% | 790,901 | $5M | $5.88 | $843K | -131,058 | -14.2% | |
| 77 | JBIO | 0.11% | 531,163 | $5M | $8.63 | -$722K | — | — | |
| 78 | QTTB | 0.11% | 2,252,987 | $4M | $1.98 | $1M | — | — | |
| 79 | CELC | 0.10% | 84,020 | $4M | $49.40 | — | +84,020 | — | NEW |
| 80 | IMTX | 0.10% | 466,601 | $4M | $8.52 | $102K | -253,300 | -35.2% | |
| 81 | IMA | 0.08% | 378,556 | $3M | $8.15 | — | +378,556 | — | NEW |
| 82 | INSM | 0.05% | 13,459 | $2M | $144.01 | $584K | — | — | |
| 83 | KRRO | 0.04% | 32,400 | $2M | $47.89 | $1M | — | — | |
| 84 | TRAW | 0.03% | 605,531 | $1M | $1.85 | $224K | — | — | |
| 85 | ANRO | 0.02% | 250,000 | $1M | $4.02 | $455K | — | — | |
| 86 | LYEL | 0.02% | 51,727 | $840K | $16.24 | $383K | — | — | |
| 87 | KZR | 0.02% | 192,700 | $752K | $3.90 | -$131K | — | — | |
| 88 | XERS | 0.02% | 80,420 | $655K | $8.14 | $279K | — | — | |
| 89 | PASG | 0.01% | 59,046 | $474K | $8.03 | — | +59,046 | — | NEW |
| 90 | AGIO | —% | — | — | — | -$19M | -557,900 | -100.0% | SOLD |
| 91 | TYRA | —% | — | — | — | -$8M | -804,603 | -100.0% | SOLD |
| 92 | CYTK | —% | — | — | — | -$36M | -1,077,000 | -100.0% | SOLD |
| 93 | CPRX | —% | — | — | — | -$9M | -416,900 | -100.0% | SOLD |
| 94 | ZLAB | —% | — | — | — | -$8M | -231,000 | -100.0% | SOLD |
| 95 | ITOS | —% | — | — | — | -$7M | -700,000 | -100.0% | SOLD |
| 96 | ABCL | —% | — | — | — | -$11M | -3,344,568 | -100.0% | SOLD |
| 97 | LSBCF | —% | — | — | — | -$56K | -54,799 | -100.0% | SOLD |
| 98 | VRTX | —% | — | — | — | -$94M | -210,287 | -100.0% | SOLD |
| 99 | IKNA | —% | — | — | — | -$5M | -3,539,358 | -100.0% | SOLD |
| 100 | THRD | —% | — | — | — | -$31M | -5,779,071 | -100.0% | SOLD |
Options Breakdown
10 Calls
$70M Call Value
2 Puts
$4M Put Value
0.06 P/C Ratio