Asset Manager
← All Institutions
ORBIMED ADVISORS LLC
Market Value
$4.5B
-6.4%
Holdings
120
+10
New Purchases
23
Added To
22
Closed
20
Reduced
33
Top 10 Concentration
44.1%
Turnover
35.8%
Top Buys (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| ELVN | 7.00% | 2.57% | +4.43% | $312M |
| AZN | 2.97% | 0.00% | +2.97% | $132M |
| EWTX | 10.97% | 8.09% | +2.88% | $489M |
| MYGN | 2.76% | 0.00% | +2.76% | $123M |
| MRK | 1.79% | 0.00% | +1.79% | $80M |
| CRVS | 2.35% | 1.16% | +1.19% | $105M |
| XENE | 1.38% | 0.42% | +0.96% | $62M |
| RCEL | 0.95% | 0.00% | +0.95% | $43M |
| GH | 0.90% | 0.00% | +0.90% | $40M |
| PRAX | 1.25% | 0.59% | +0.66% | $56M |
| SNDX | 0.50% | 0.00% | +0.50% | $22M |
| MLYS | 1.25% | 0.75% | +0.50% | $56M |
| RLMD | 0.74% | 0.26% | +0.47% | $33M |
| STRO | 0.45% | 0.00% | +0.45% | $20M |
| NKTR | 0.44% | 0.00% | +0.44% | $20M |
Top Sells (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| UPB | 1.15% | 3.25% | -2.10% | $51M |
| LLY | 4.89% | 6.80% | -1.91% | $218M |
| TERN | 0.00% | 1.83% | -1.83% | $0 |
| ALNY | 0.88% | 2.41% | -1.53% | $39M |
| BSX | 3.36% | 4.85% | -1.49% | $149M |
| APLS | 0.00% | 1.28% | -1.28% | $0 |
| CI | 0.00% | 1.19% | -1.19% | $0 |
| RAPT | 0.00% | 1.17% | -1.17% | $0 |
| EW | 2.21% | 3.30% | -1.09% | $99M |
| UTHR | 0.00% | 1.08% | -1.08% | $0 |
| SYK | 1.35% | 2.40% | -1.05% | $60M |
| ROIV | 0.00% | 1.00% | -1.00% | $0 |
| ISRG | 2.16% | 3.13% | -0.97% | $96M |
| RNAM | 0.00% | 0.94% | -0.94% | $0 |
| NBIX | 0.00% | 0.94% | -0.94% | $0 |
Sector Allocation Over Time
Market Cap Concentration
| Tier | Holdings | Value | Weight |
|---|---|---|---|
| Mega Cap | 5 | $467M | 10.5% |
| Large Cap | 24 | $888M | 19.9% |
| Mid Cap | 29 | $1.6B | 34.9% |
| Small Cap | 39 | $1.1B | 24.1% |
| Micro Cap | 23 | $470M | 10.6% |
Portfolio Analytics
Avg Market Cap
$32.8B
Median Market Cap
$1.9B
Avg P/E
38.7
Median P/E
36.4
Avg Dividend Yield
0.01%
Avg Beta
0.91
# Stocks
120
# ETFs / Funds
0
Top Holdings (120 total)
| # | Symbol | % Port | Shares | Value | Avg Price | Q/Q Value Chg | Share Chg | Chg % | Status |
|---|---|---|---|---|---|---|---|---|---|
| 1 | EWTX | 10.97% | 15,518,492 | $489M | $31.50 | $104M | — | — | |
| 2 | ELVN | 7.00% | 7,959,538 | $312M | $39.20 | $189M | — | — | |
| 3 | LLY | 4.89% | 236,800 | $218M | $919.77 | -$106M | -64,400 | -21.4% | |
| 4 | SVA | 4.14% | 2,718,735 | $184M | $67.85 | — | — | — | |
| 5 | BSX | 3.36% | 2,382,100 | $149M | $62.75 | -$81M | -37,200 | -1.5% | |
| 6 | SION | 3.18% | 3,530,702 | $142M | $40.09 | -$5M | -30,953 | -0.9% | |
| 7 | AZN | 2.97% | 670,200 | $132M | $197.22 | — | +670,200 | — | NEW |
| 8 | MYGN | 2.76% | 125,000,000 | $123M | $0.98 | — | +125,000,000 | — | NEW |
| 9 | MBX | 2.44% | 3,637,887 | $109M | $29.85 | -$16M | -297,316 | -7.6% | |
| 10 | CRVS | 2.35% | 7,165,006 | $105M | $14.63 | $50M | — | — | |
| 11 | ARGX | 2.24% | 136,900 | $100M | $730.25 | -$23M | -9,100 | -6.2% | |
| 12 | EW | 2.21% | 1,230,600 | $99M | $80.08 | -$59M | -612,300 | -33.2% | |
| 13 | ISRG | 2.16% | 208,700 | $96M | $460.99 | -$53M | -54,700 | -20.8% | |
| 14 | CMPX | 1.81% | 15,219,994 | $81M | $5.29 | -$1M | — | — | |
| 15 | MRK | 1.79% | 663,400 | $80M | $120.29 | — | +663,400 | — | NEW |
| 16 | GPCR | 1.60% | 1,475,403 | $71M | $48.20 | -$10M | +313,600 | +27.0% | |
| 17 | AVBP | 1.57% | 3,027,328 | $70M | $23.07 | $9M | — | — | |
| 18 | IRON | 1.53% | 1,067,550 | $68M | $63.94 | -$17M | — | — | |
| 19 | SBTX | 1.49% | 8,288,510 | $67M | $8.03 | -$30M | — | — | |
| 20 | CGON | 1.44% | 948,267 | $64M | $67.68 | $1M | -568,283 | -37.5% | |
| 21 | XENE | 1.38% | 1,059,971 | $62M | $58.15 | $42M | +612,771 | +137.0% | |
| 22 | SYK | 1.35% | 182,500 | $60M | $328.59 | -$54M | -142,500 | -43.9% | |
| 23 | BMY | 1.26% | 925,000 | $56M | $60.65 | $14M | +150,000 | +19.4% | |
| 24 | MLYS | 1.25% | 2,052,900 | $56M | $27.09 | $20M | +1,072,500 | +109.4% | |
| 25 | PRAX | 1.25% | 172,500 | $56M | $322.19 | $28M | +78,000 | +82.5% | |
| 26 | PFE | 1.23% | 1,946,500 | $55M | $28.08 | $14M | +293,600 | +17.8% | |
| 27 | DYN | 1.19% | 2,917,884 | $53M | $18.13 | $10M | +715,700 | +32.5% | |
| 28 | NTRA | 1.18% | 262,000 | $52M | $199.99 | -$31M | -103,800 | -28.4% | |
| 29 | ABVX | 1.16% | 465,700 | $52M | $111.35 | $2M | +97,800 | +26.6% | |
| 30 | UPB | 1.15% | 5,693,589 | $51M | $9.00 | -$103M | — | — | |
| 31 | DHR | 1.13% | 265,800 | $50M | $189.60 | -$18M | -34,000 | -11.3% | |
| 32 | CAI | 1.13% | 2,806,811 | $50M | $17.88 | -$34M | -309,200 | -9.9% | |
| 33 | RCEL | 0.95% | 41,044,895 | $43M | $1.04 | — | +41,044,895 | — | NEW |
| 34 | STTK | 0.91% | 6,306,127 | $41M | $6.43 | $18M | — | — | |
| 35 | GH | 0.90% | 435,200 | $40M | $92.37 | — | +435,200 | — | NEW |
| 36 | ALNY | 0.88% | 119,000 | $39M | $330.87 | -$75M | -169,800 | -58.8% | |
| 37 | PRLD | 0.84% | 10,909,256 | $37M | $3.42 | $6M | — | — | |
| 38 | CRNX | 0.81% | 999,000 | $36M | $36.32 | -$10M | — | — | |
| 39 | AXSM | 0.81% | 213,921 | $36M | $169.02 | -$10M | -39,200 | -15.5% | |
| 40 | ORIC | 0.77% | 2,693,929 | $34M | $12.67 | $4M | -947,827 | -26.0% | |
| 41 | ANTM | 0.75% | 114,700 | $34M | $292.75 | -$1M | +15,600 | +15.7% | |
| 42 | RLMD | 0.74% | 4,715,864 | $33M | $6.96 | $20M | +2,105,264 | +80.6% | |
| 43 | FBRX | 0.70% | 1,196,955 | $31M | $25.90 | -$2M | — | — | |
| 44 | TRVI | 0.66% | 2,454,400 | $29M | $11.93 | -$11M | -736,300 | -23.1% | |
| 45 | ESPR | 0.65% | 10,570,300 | $29M | $2.74 | $7M | +4,604,802 | +77.2% | |
| 46 | NPCE | 0.62% | 2,096,527 | $28M | $13.15 | -$10M | -309,808 | -12.9% | |
| 47 | RYTM | 0.61% | 314,100 | $27M | $86.97 | $2M | +74,300 | +31.0% | |
| 48 | TMO | 0.51% | 46,500 | $23M | $491.53 | -$4M | — | — | |
| 49 | SNDX | 0.50% | 962,300 | $22M | $23.36 | — | +962,300 | — | NEW |
| 50 | BTSG | 0.48% | 497,800 | $21M | $42.61 | $3M | +9,300 | +1.9% | |
| 51 | LXEO | 0.46% | 3,602,450 | $21M | $5.74 | -$423K | +1,477,450 | +69.5% | |
| 52 | STRO | 0.45% | 801,144 | $20M | $24.91 | — | +801,144 | — | NEW |
| 53 | NKTR | 0.44% | 275,000 | $20M | $71.95 | — | +275,000 | — | NEW |
| 54 | CYBN | 0.41% | 3,832,843 | $18M | $4.80 | -$13M | -7,657 | -0.2% | |
| 55 | KRYS | 0.40% | 69,100 | $18M | $258.32 | -$12M | -50,700 | -42.3% | |
| 56 | PVLA | 0.38% | 134,600 | $17M | $124.65 | — | +134,600 | — | NEW |
| 57 | CRBP | 0.37% | 1,737,287 | $16M | $9.39 | $3M | +140,000 | +8.8% | |
| 58 | DFTX | 0.34% | 804,000 | $15M | $18.90 | — | +804,000 | — | NEW |
| 59 | VERA | 0.33% | 369,596 | $15M | $40.23 | -$3M | +16,096 | +4.5% | |
| 60 | QTTB | 0.32% | 2,252,987 | $14M | $6.42 | $7M | — | — | |
| 61 | WHWK | 0.32% | 4,166,000 | $14M | $3.45 | $4M | — | — | |
| 62 | AMGN | 0.32% | 39,900 | $14M | $351.85 | — | +39,900 | — | NEW |
| 63 | ALHC | 0.31% | 791,000 | $14M | $17.62 | — | +791,000 | — | NEW |
| 64 | EYPT | 0.31% | 1,069,147 | $14M | $12.89 | -$31M | -1,399,167 | -56.7% | |
| 65 | JANX | 0.31% | 983,600 | $14M | $13.90 | -$13M | -970,826 | -49.7% | |
| 66 | BCRX | 0.30% | 1,425,200 | $14M | $9.52 | -$18K | -316,600 | -18.2% | |
| 67 | BCAX | 0.30% | 667,300 | $13M | $19.89 | $10M | +458,200 | +219.1% | |
| 68 | BIOA | 0.28% | 711,811 | $12M | $17.49 | $2M | -79,090 | -10.0% | |
| 69 | COGT | 0.28% | 322,100 | $12M | $38.49 | -$780K | -48,900 | -13.2% | |
| 70 | ALMS | 0.27% | 548,163 | $12M | $22.03 | $1M | -554,567 | -50.3% | |
| 71 | REGN | 0.25% | 14,700 | $11M | $772.64 | — | +14,700 | — | NEW |
| 72 | CARL | 0.25% | 1,252,600 | $11M | $9.05 | -$4M | — | — | |
| 73 | BIIB | 0.25% | 61,600 | $11M | $183.33 | — | +61,600 | — | NEW |
| 74 | KROS | 0.19% | 759,155 | $8M | $11.04 | -$8M | -45,057 | -5.6% | |
| 75 | GILD | 0.19% | 59,600 | $8M | $139.37 | — | +59,600 | — | NEW |
| 76 | HRTX | 0.18% | 9,816,940 | $8M | $0.80 | — | +9,816,940 | — | NEW |
| 77 | AVTX | 0.16% | 475,165 | $7M | $14.93 | -$14M | -712,135 | -60.0% | |
| 78 | TECX | 0.16% | 226,600 | $7M | $30.91 | -$5M | -348,000 | -60.6% | |
| 79 | ACET | 0.16% | 1,027,944 | $7M | $6.81 | -$2M | — | — | |
| 80 | CMPS | 0.14% | 1,150,646 | $6M | $5.53 | — | +1,150,646 | — | NEW |
| 81 | ALXO | 0.13% | 2,866,256 | $6M | $2.00 | — | +2,866,256 | — | NEW |
| 82 | AORT | 0.12% | 151,000 | $6M | $36.62 | — | +151,000 | — | NEW |
| 83 | NSPR | 0.11% | 3,133,405 | $5M | $1.63 | -$470K | — | — | |
| 84 | RVMD | 0.11% | 52,000 | $5M | $97.25 | $3M | +26,100 | +100.8% | |
| 85 | ADCT | 0.11% | 1,318,026 | $5M | $3.75 | -$16M | -4,504,828 | -77.4% | |
| 86 | PTGX | 0.10% | 42,100 | $4M | $105.40 | $3M | +20,400 | +94.0% | |
| 87 | PALI | 0.09% | 2,333,000 | $4M | $1.75 | -$315K | +461,580 | +24.7% | |
| 88 | ANRO | 0.08% | 167,500 | $4M | $22.48 | $2M | +42,500 | +34.0% | |
| 89 | SVRA | 0.08% | 635,000 | $3M | $5.46 | — | +635,000 | — | NEW |
| 90 | CGEM | 0.08% | 243,006 | $3M | $14.21 | $659K | -27,000 | -10.0% | |
| 91 | PTCT | 0.08% | 49,100 | $3M | $68.13 | $2M | +25,900 | +111.6% | |
| 92 | LFST | 0.07% | 500,000 | $3M | $6.37 | — | +500,000 | — | NEW |
| 93 | DRUG | 0.07% | 40,000 | $3M | $72.97 | — | +40,000 | — | NEW |
| 94 | JBIO | 0.06% | 185,011 | $3M | $14.05 | -$6M | -346,152 | -65.2% | |
| 95 | CCCC | 0.05% | 856,353 | $2M | $2.63 | -$431K | -548,549 | -39.0% | |
| 96 | KALV | 0.04% | 94,400 | $2M | $20.13 | -$4M | -288,000 | -75.3% | |
| 97 | IMA | 0.04% | 378,556 | $2M | $5.00 | -$719K | — | — | |
| 98 | VTGN | 0.04% | 3,060,000 | $2M | $0.57 | -$277K | — | — | |
| 99 | ATAI | 0.03% | 347,000 | $1M | $3.54 | — | +347,000 | — | NEW |
| 100 | TRAW | 0.02% | 605,531 | $1M | $1.83 | $424K | — | — |