Asset Manager
← All Institutions
ORBIMED ADVISORS LLC
Market Value
$4.8B
+17.3%
Holdings
110
+7
New Purchases
21
Added To
18
Closed
13
Reduced
34
Top 10 Concentration
41.6%
Turnover
30.9%
Top Buys (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| EWTX | 8.09% | 6.20% | +1.89% | $385M |
| LLY | 6.80% | 5.66% | +1.14% | $324M |
| GPCR | 1.70% | 0.79% | +0.91% | $81M |
| MBX | 2.61% | 1.73% | +0.88% | $124M |
| BMY | 0.88% | 0.00% | +0.88% | $42M |
| PFE | 0.86% | 0.00% | +0.86% | $41M |
| ANTM | 0.73% | 0.00% | +0.73% | $35M |
| HELP | 0.66% | 0.00% | +0.66% | $31M |
| UPB | 3.25% | 2.64% | +0.61% | $155M |
| PRAX | 0.59% | 0.00% | +0.59% | $28M |
| BRKR | 0.55% | 0.00% | +0.55% | $26M |
| RAPT | 1.17% | 0.69% | +0.48% | $56M |
| ESPR | 0.46% | 0.00% | +0.46% | $22M |
| LXEO | 0.44% | 0.00% | +0.44% | $21M |
| TERN | 1.83% | 1.40% | +0.43% | $87M |
Top Sells (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| ELVN | 2.57% | 4.01% | -1.44% | $123M |
| BSX | 4.85% | 5.84% | -1.00% | $231M |
| ALNY | 2.41% | 3.39% | -0.98% | $115M |
| SIBN | 0.00% | 0.94% | -0.94% | $0 |
| SYK | 2.40% | 3.27% | -0.87% | $114M |
| SCPH | 0.00% | 0.85% | -0.85% | $0 |
| RNAM | 0.94% | 1.76% | -0.82% | $45M |
| ITGR | 0.00% | 0.74% | -0.74% | $0 |
| SVA | 3.87% | 4.54% | -0.67% | $184M |
| MLYS | 0.75% | 1.37% | -0.63% | $36M |
| AXSM | 0.97% | 1.59% | -0.62% | $46M |
| AKRO | 0.00% | 0.62% | -0.62% | $0 |
| EXAS | 0.75% | 1.34% | -0.59% | $36M |
| ARGX | 2.58% | 3.13% | -0.55% | $123M |
| IRON | 1.78% | 2.30% | -0.52% | $85M |
Sector Allocation Over Time
Market Cap Concentration
| Tier | Holdings | Value | Weight |
|---|---|---|---|
| Mega Cap | 2 | $351M | 7.4% |
| Large Cap | 20 | $1.5B | 30.8% |
| Mid Cap | 29 | $1.4B | 30.3% |
| Small Cap | 34 | $907M | 19.0% |
| Micro Cap | 25 | $597M | 12.5% |
Portfolio Analytics
Avg Market Cap
$25.5B
Median Market Cap
$1.6B
Avg P/E
35.0
Median P/E
35.6
Avg Dividend Yield
0.00%
Avg Beta
0.87
# Stocks
110
# ETFs / Funds
0
Top Holdings (110 total)
| # | Symbol | % Port | Shares | Value | Avg Price | Q/Q Value Chg | Share Chg | Chg % | Status |
|---|---|---|---|---|---|---|---|---|---|
| 1 | EWTX | 8.09% | 15,518,492 | $385M | $24.82 | $133M | — | — | |
| 2 | LLY | 6.80% | 301,200 | $324M | $1,074.68 | $94M | — | — | |
| 3 | BSX | 4.85% | 2,419,300 | $231M | $95.35 | -$6M | -10,000 | -0.4% | |
| 4 | SVA | 3.87% | 2,718,735 | $184M | $67.85 | — | — | — | |
| 5 | EW | 3.30% | 1,842,900 | $157M | $85.25 | $26M | +158,900 | +9.4% | |
| 6 | UPB | 3.25% | 5,693,589 | $155M | $27.15 | $47M | — | — | |
| 7 | ISRG | 3.13% | 263,400 | $149M | $566.36 | $21M | -23,800 | -8.3% | |
| 8 | SION | 3.08% | 3,561,655 | $147M | $41.14 | $38M | -143,304 | -3.9% | |
| 9 | MBX | 2.61% | 3,935,203 | $124M | $31.54 | $54M | -67,684 | -1.7% | |
| 10 | ARGX | 2.58% | 146,000 | $123M | $840.95 | -$4M | -26,300 | -15.3% | |
| 11 | ELVN | 2.57% | 7,959,538 | $123M | $15.40 | -$40M | — | — | |
| 12 | ALNY | 2.41% | 288,800 | $115M | $397.65 | -$23M | -12,800 | -4.2% | |
| 13 | SYK | 2.40% | 325,000 | $114M | $351.47 | -$19M | -34,200 | -9.5% | |
| 14 | SBTX | 2.03% | 8,288,510 | $97M | $11.65 | $13M | — | — | |
| 15 | TERN | 1.83% | 2,153,300 | $87M | $40.40 | $30M | -5,409,671 | -71.5% | |
| 16 | IRON | 1.78% | 1,067,550 | $85M | $79.41 | -$9M | -347,470 | -24.6% | |
| 17 | CAI | 1.77% | 3,116,011 | $84M | $26.98 | -$8M | +81,153 | +2.7% | |
| 18 | NTRA | 1.76% | 365,800 | $84M | $229.09 | $15M | -63,500 | -14.8% | |
| 19 | CMPX | 1.72% | 15,219,994 | $82M | $5.37 | $28M | — | — | |
| 20 | GPCR | 1.70% | 1,161,803 | $81M | $69.55 | $49M | +22,503 | +2.0% | |
| 21 | DHR | 1.44% | 299,800 | $69M | $228.92 | $16M | +36,700 | +13.9% | |
| 22 | CGON | 1.32% | 1,516,550 | $63M | $41.52 | -$7M | -210,300 | -12.2% | |
| 23 | APLS | 1.28% | 2,429,868 | $61M | $25.12 | $8M | +106,500 | +4.6% | |
| 24 | AVBP | 1.28% | 3,027,328 | $61M | $20.12 | $5M | — | — | |
| 25 | CI | 1.19% | 205,000 | $56M | $275.23 | $9M | +42,200 | +25.9% | |
| 26 | RAPT | 1.17% | 1,642,891 | $56M | $33.87 | $28M | +556,273 | +51.2% | |
| 27 | CRVS | 1.16% | 7,165,006 | $55M | $7.70 | $2M | — | — | |
| 28 | UTHR | 1.08% | 105,200 | $51M | $487.25 | $3M | -9,700 | -8.4% | |
| 29 | ABVX | 1.04% | 367,900 | $50M | $134.86 | $17M | -12,100 | -3.2% | |
| 30 | ROIV | 1.00% | 2,190,907 | $48M | $21.70 | $6M | -523,891 | -19.3% | |
| 31 | CRNX | 0.98% | 999,000 | $47M | $46.55 | $730K | -100,000 | -9.1% | |
| 32 | AXSM | 0.97% | 253,121 | $46M | $182.64 | -$18M | -278,679 | -52.4% | |
| 33 | EYPT | 0.95% | 2,468,314 | $45M | $18.27 | $20M | +672,314 | +37.4% | |
| 34 | RNAM | 0.94% | 619,530 | $45M | $72.13 | -$27M | -1,019,356 | -62.2% | |
| 35 | NBIX | 0.94% | 314,240 | $45M | $141.83 | -$5M | -39,400 | -11.1% | |
| 36 | DYN | 0.90% | 2,202,184 | $43M | $19.56 | $14M | -112,000 | -4.8% | |
| 37 | BMY | 0.88% | 775,000 | $42M | $53.94 | — | +775,000 | — | NEW |
| 38 | PFE | 0.86% | 1,652,900 | $41M | $24.90 | — | +1,652,900 | — | NEW |
| 39 | TRVI | 0.84% | 3,190,700 | $40M | $12.52 | $10M | -117,700 | -3.6% | |
| 40 | NPCE | 0.78% | 2,406,335 | $37M | $15.44 | $10M | -207,849 | -8.0% | |
| 41 | EXAS | 0.75% | 351,716 | $36M | $101.56 | -$19M | -642,900 | -64.6% | |
| 42 | MLYS | 0.75% | 980,400 | $36M | $36.29 | -$20M | -489,094 | -33.3% | |
| 43 | ANTM | 0.73% | 99,100 | $35M | $350.55 | — | +99,100 | — | NEW |
| 44 | FBRX | 0.69% | 1,196,955 | $33M | $27.27 | $15M | — | — | |
| 45 | PRLD | 0.66% | 10,909,256 | $32M | $2.90 | $16M | — | — | |
| 46 | HELP | 0.66% | 3,840,500 | $31M | $8.18 | — | +3,840,500 | — | NEW |
| 47 | ORIC | 0.63% | 3,641,756 | $30M | $8.18 | -$14M | — | — | |
| 48 | KRYS | 0.62% | 119,800 | $30M | $246.54 | $11M | +17,055 | +16.6% | |
| 49 | PRAX | 0.59% | 94,500 | $28M | $294.74 | — | +94,500 | — | NEW |
| 50 | JANX | 0.57% | 1,954,426 | $27M | $13.80 | -$16M | +188,326 | +10.7% | |
| 51 | TMO | 0.57% | 46,500 | $27M | $579.45 | $4M | — | — | |
| 52 | BRKR | 0.55% | 555,789 | $26M | $47.11 | — | +555,789 | — | NEW |
| 53 | RYTM | 0.54% | 239,800 | $26M | $107.04 | $4M | +24,648 | +11.5% | |
| 54 | STTK | 0.48% | 6,306,127 | $23M | $3.65 | $8M | — | — | |
| 55 | ESPR | 0.46% | 5,965,498 | $22M | $3.70 | — | +5,965,498 | — | NEW |
| 56 | AVTX | 0.45% | 1,187,300 | $22M | $18.16 | $4M | -162,000 | -12.0% | |
| 57 | LXEO | 0.44% | 2,125,000 | $21M | $9.93 | — | +2,125,000 | — | NEW |
| 58 | ADCT | 0.43% | 5,822,854 | $21M | $3.53 | -$3M | -84,497 | -1.4% | |
| 59 | XENE | 0.42% | 447,200 | $20M | $44.82 | $3M | +27,600 | +6.6% | |
| 60 | BTSG | 0.38% | 488,500 | $18M | $37.45 | $10M | +224,700 | +85.2% | |
| 61 | VERA | 0.38% | 353,500 | $18M | $50.64 | — | +353,500 | — | NEW |
| 62 | KROS | 0.34% | 804,212 | $16M | $20.36 | $257K | -214,522 | -21.1% | |
| 63 | CARL | 0.32% | 1,252,600 | $15M | $12.35 | -$1M | — | — | |
| 64 | CTMX | 0.32% | 3,525,650 | $15M | $4.26 | -$12M | -4,935,850 | -58.3% | |
| 65 | VIR | 0.30% | 2,380,715 | $14M | $6.03 | $762K | — | — | |
| 66 | BCRX | 0.29% | 1,741,800 | $14M | $7.80 | $7M | +840,300 | +93.2% | |
| 67 | COGT | 0.28% | 371,000 | $13M | $35.52 | — | +371,000 | — | NEW |
| 68 | CRBP | 0.27% | 1,597,287 | $13M | $8.14 | -$2M | +425,000 | +36.2% | |
| 69 | TARS | 0.27% | 154,400 | $13M | $81.88 | $881K | -43,500 | -22.0% | |
| 70 | RLMD | 0.26% | 2,610,600 | $13M | $4.83 | — | +2,610,600 | — | NEW |
| 71 | TECX | 0.25% | 574,600 | $12M | $20.86 | — | +574,600 | — | NEW |
| 72 | ALMS | 0.23% | 1,102,730 | $11M | $9.76 | $3M | -823,693 | -42.8% | |
| 73 | BIOA | 0.22% | 790,901 | $10M | $13.23 | $6M | — | — | |
| 74 | FOLD | 0.22% | 729,900 | $10M | $14.24 | -$3M | -915,500 | -55.6% | |
| 75 | WHWK | 0.21% | 4,166,000 | $10M | $2.42 | $2M | — | — | |
| 76 | ACET | 0.18% | 1,027,944 | $9M | $8.42 | — | +1,027,944 | — | NEW |
| 77 | RPTX | 0.18% | 3,322,488 | $9M | $2.60 | $3M | — | — | |
| 78 | CELC | 0.18% | 85,664 | $9M | $99.74 | $4M | +1,644 | +2.0% | |
| 79 | JBIO | 0.17% | 531,163 | $8M | $15.43 | $4M | — | — | |
| 80 | QTTB | 0.16% | 2,252,987 | $7M | $3.32 | $3M | — | — | |
| 81 | PMVP | 0.13% | 4,975,291 | $6M | $1.25 | -$2M | -1,000,000 | -16.7% | |
| 82 | KALV | 0.13% | 382,400 | $6M | $16.15 | — | +382,400 | — | NEW |
| 83 | NSPR | 0.12% | 3,133,405 | $6M | $1.78 | $436K | +1,000,000 | +46.9% | |
| 84 | INSM | 0.09% | 25,400 | $4M | $174.04 | $2M | +11,941 | +88.7% | |
| 85 | PALI | 0.09% | 1,871,420 | $4M | $2.35 | — | +1,871,420 | — | NEW |
| 86 | BCAX | 0.07% | 209,100 | $4M | $16.83 | — | +209,100 | — | NEW |
| 87 | CGEM | 0.06% | 270,006 | $3M | $10.35 | -$9M | -1,653,849 | -86.0% | |
| 88 | CCCC | 0.06% | 1,404,902 | $3M | $1.91 | -$9M | -3,830,244 | -73.2% | |
| 89 | IMA | 0.05% | 378,556 | $3M | $6.90 | -$473K | — | — | |
| 90 | ANRO | 0.05% | 125,000 | $2M | $17.80 | $1M | -125,000 | -50.0% | |
| 91 | RVMD | 0.04% | 25,900 | $2M | $79.65 | — | +25,900 | — | NEW |
| 92 | VTGN | 0.04% | 3,060,000 | $2M | $0.66 | -$9M | — | — | |
| 93 | OCUL | 0.04% | 157,300 | $2M | $12.14 | — | +157,300 | — | NEW |
| 94 | PTGX | 0.04% | 21,700 | $2M | $87.34 | — | +21,700 | — | NEW |
| 95 | PTCT | 0.04% | 23,200 | $2M | $75.96 | — | +23,200 | — | NEW |
| 96 | MPLT | 0.02% | 56,000 | $952K | $17.00 | — | +56,000 | — | NEW |
| 97 | TRAW | 0.01% | 605,531 | $684K | $1.13 | -$436K | — | — | |
| 98 | AMLX | —% | — | — | — | -$10M | -750,600 | -100.0% | SOLD |
| 99 | SIBN | —% | — | — | — | -$38M | -2,578,979 | -100.0% | SOLD |
| 100 | LYEL | —% | — | — | — | -$840K | -51,727 | -100.0% | SOLD |
Options Breakdown
9 Calls
$13M Call Value
1 Puts
$0 Put Value
0.0 P/C Ratio