Asset Manager
← All Institutions
Siren, L.L.C.
Market Value
$1.8B
+11.3%
Holdings
122
-10
New Purchases
14
Added To
21
Closed
21
Reduced
16
Top 10 Concentration
53.2%
Turnover
28.7%
Top Buys (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| KYMR | 8.50% | 5.61% | +2.89% | $150M |
| MLTX | 1.36% | 0.00% | +1.36% | $24M |
| AKRO | 0.97% | 0.00% | +0.97% | $17M |
| LXRX | 2.09% | 1.13% | +0.96% | $37M |
| TSHA | 1.45% | 0.57% | +0.87% | $25M |
| AVBP | 0.87% | 0.00% | +0.87% | $15M |
| DYN | 2.62% | 1.80% | +0.82% | $46M |
| TNGX | 0.98% | 0.22% | +0.76% | $17M |
| RVMD | 1.96% | 1.26% | +0.70% | $35M |
| RYTM | 1.47% | 0.93% | +0.54% | $26M |
| SEPN | 1.32% | 0.81% | +0.52% | $23M |
| STOK | 1.45% | 0.94% | +0.50% | $26M |
| SLN | 0.96% | 0.50% | +0.46% | $17M |
| COGT | 0.35% | 0.00% | +0.35% | $6M |
| PCRX | 0.31% | 0.00% | +0.31% | $5M |
Top Sells (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| BPMC | 0.00% | 4.06% | -4.06% | $0 |
| ONC | 7.01% | 8.58% | -1.57% | $123M |
| APLS | 2.54% | 3.56% | -1.03% | $45M |
| PRTA | 0.00% | 1.00% | -1.00% | $0 |
| SMMT | 0.00% | 0.85% | -0.85% | $0 |
| CRNX | 2.76% | 3.58% | -0.82% | $49M |
| VERA | 0.33% | 1.13% | -0.80% | $6M |
| WVE | 1.36% | 1.89% | -0.52% | $24M |
| RNAM | 1.79% | 2.07% | -0.28% | $32M |
| MTSR | 0.00% | 0.26% | -0.26% | $0 |
| MRUS | 2.55% | 2.78% | -0.23% | $45M |
| MSFT | 0.46% | 0.68% | -0.22% | $8M |
| SRRK | 18.61% | 18.80% | -0.19% | $328M |
| BCYC | 0.79% | 0.97% | -0.18% | $14M |
| RCKT | 0.08% | 0.25% | -0.17% | $1M |
Sector Allocation Over Time
Market Cap Concentration
| Tier | Holdings | Value | Weight |
|---|---|---|---|
| Mega Cap | 9 | $49M | 2.8% |
| Large Cap | 31 | $291M | 16.5% |
| Mid Cap | 39 | $1.0B | 57.7% |
| Small Cap | 26 | $331M | 18.8% |
| Micro Cap | 17 | $73M | 4.2% |
Portfolio Analytics
Avg Market Cap
$188.6B
Median Market Cap
$4.5B
Avg P/E
54.1
Median P/E
30.3
Avg Dividend Yield
0.00%
Avg Beta
1.11
# Stocks
122
# ETFs / Funds
0
Top Holdings (122 total)
| # | Symbol | % Port | Shares | Value | Avg Price | Q/Q Value Chg | Share Chg | Chg % | Status |
|---|---|---|---|---|---|---|---|---|---|
| 1 | SRRK | 18.61% | 9,250,005 | $328M | $35.42 | $30M | — | — | |
| 2 | KYMR | 8.50% | 3,428,150 | $150M | $43.64 | $61M | +187,837 | +5.8% | |
| 3 | ONC | 7.01% | 509,990 | $123M | $242.07 | -$12M | +11,301 | +2.3% | |
| 4 | IRON | 3.31% | 1,099,401 | $58M | $52.96 | $5M | +27,536 | +2.6% | |
| 5 | CRNX | 2.76% | 1,688,611 | $49M | $28.76 | -$8M | — | — | |
| 6 | BCAX | 2.75% | 5,216,969 | $48M | $9.29 | $6M | +1,949,886 | +59.7% | |
| 7 | DYN | 2.62% | 4,836,437 | $46M | $9.52 | $18M | +2,118,450 | +77.9% | |
| 8 | CNTA | 2.58% | 3,460,029 | $45M | $13.14 | $3M | +500,000 | +16.9% | |
| 9 | MRUS | 2.55% | 853,467 | $45M | $52.60 | $973K | -190,000 | -18.2% | |
| 10 | APLS | 2.54% | 2,578,396 | $45M | $17.31 | -$12M | — | — | |
| 11 | ARWR | 2.40% | 2,669,880 | $42M | $15.80 | $8M | — | — | |
| 12 | EWTX | 2.35% | 3,160,298 | $41M | $13.11 | $4M | +1,463,854 | +86.3% | |
| 13 | LXRX | 2.09% | 38,918,903 | $37M | $0.95 | $19M | — | — | |
| 14 | TBLA | 2.07% | 9,969,495 | $36M | $3.66 | $7M | — | — | |
| 15 | RVMD | 1.96% | 938,755 | $35M | $36.79 | $15M | +375,000 | +66.5% | |
| 16 | RNAM | 1.79% | 1,110,610 | $32M | $28.40 | -$1M | — | — | |
| 17 | RYTM | 1.47% | 409,742 | $26M | $63.19 | $11M | +132,209 | +47.6% | |
| 18 | STOK | 1.45% | 2,247,347 | $26M | $11.35 | $11M | — | — | |
| 19 | TSHA | 1.45% | 11,014,737 | $25M | $2.31 | $16M | +4,500,000 | +69.1% | |
| 20 | XENE | 1.45% | 812,761 | $25M | $31.30 | $855K | +80,000 | +10.9% | |
| 21 | WVE | 1.36% | 3,696,322 | $24M | $6.50 | -$6M | — | — | |
| 22 | MLTX | 1.36% | 508,267 | $24M | $47.20 | — | +508,267 | — | NEW |
| 23 | SEPN | 1.32% | 2,202,514 | $23M | $10.57 | $11M | — | — | |
| 24 | TRVI | 1.22% | 3,938,793 | $22M | $5.47 | $4M | +1,075,000 | +37.5% | |
| 25 | TNGX | 0.98% | 3,364,814 | $17M | $5.12 | $14M | +799,472 | +31.2% | |
| 26 | AKRO | 0.97% | 318,647 | $17M | $53.36 | — | +318,647 | — | NEW |
| 27 | SLN | 0.96% | 2,911,438 | $17M | $5.80 | $9M | +121,605 | +4.4% | |
| 28 | AVBP | 0.87% | 700,000 | $15M | $21.77 | — | +700,000 | — | NEW |
| 29 | BCYC | 0.79% | 2,012,752 | $14M | $6.95 | -$1M | +200,000 | +11.0% | |
| 30 | RCUS | 0.75% | 1,612,077 | $13M | $8.14 | $468K | — | — | |
| 31 | IHS | 0.74% | 2,357,520 | $13M | $5.56 | $802K | — | — | |
| 32 | AMZN | 0.70% | 56,500 | $12M | $219.39 | $2M | — | — | |
| 33 | DNLI | 0.65% | 821,513 | $11M | $13.99 | $324K | — | — | |
| 34 | ERAS | 0.63% | 8,757,249 | $11M | $1.27 | -$876K | — | — | |
| 35 | ORIC | 0.58% | 1,007,575 | $10M | $10.15 | $5M | — | — | |
| 36 | RELY | 0.55% | 515,449 | $10M | $18.77 | -$526K | +25,000 | +5.1% | |
| 37 | PCVX | 0.55% | 295,543 | $10M | $32.51 | -$2M | — | — | |
| 38 | CRWD | 0.54% | 18,500 | $9M | $509.31 | $608K | -6,500 | -26.0% | |
| 39 | CGEM | 0.51% | 1,193,410 | $9M | $7.53 | -$48K | — | — | |
| 40 | GOOGL | 0.51% | 50,703 | $9M | $176.20 | $1M | — | — | |
| 41 | UPB | 0.49% | 788,450 | $9M | $10.98 | $4M | — | — | |
| 42 | SEER | 0.49% | 4,000,000 | $9M | $2.14 | $2M | — | — | |
| 43 | MSFT | 0.46% | 16,150 | $8M | $497.41 | -$3M | -12,350 | -43.3% | |
| 44 | NVDA | 0.45% | 49,985 | $8M | $157.99 | $3M | +5,553 | +12.5% | |
| 45 | IONQ | 0.41% | 170,000 | $7M | $42.97 | $4M | — | — | |
| 46 | TSM | 0.39% | 30,500 | $7M | $226.49 | $2M | +2,000 | +7.0% | |
| 47 | GOSS | 0.36% | 5,208,968 | $6M | $1.23 | $677K | — | — | |
| 48 | CRM | 0.35% | 22,600 | $6M | $272.69 | $2M | +8,000 | +54.8% | |
| 49 | COGT | 0.35% | 854,379 | $6M | $7.18 | — | +854,379 | — | NEW |
| 50 | RNAC | 0.33% | 563,272 | $6M | $10.39 | -$2M | — | — | |
| 51 | VERA | 0.33% | 247,216 | $6M | $23.56 | -$12M | -500,000 | -66.9% | |
| 52 | ADBE | 0.33% | 15,051 | $6M | $386.88 | -$2M | -4,247 | -22.0% | |
| 53 | SION | 0.32% | 325,000 | $6M | $17.35 | $2M | — | — | |
| 54 | PDD | 0.31% | 52,901 | $6M | $104.66 | -$724K | — | — | |
| 55 | SGMT | 0.31% | 724,771 | $6M | $7.62 | $3M | — | — | |
| 56 | SYRE | 0.31% | 368,598 | $6M | $14.97 | -$429K | — | — | |
| 57 | PCRX | 0.31% | 225,000 | $5M | $23.90 | — | +225,000 | — | NEW |
| 58 | NOW | 0.30% | 5,126 | $5M | $1,028.08 | -$2M | -4,000 | -43.8% | |
| 59 | KRRO | 0.30% | 418,833 | $5M | $12.49 | -$2M | — | — | |
| 60 | DDOG | 0.29% | 38,425 | $5M | $134.33 | $457K | -9,000 | -19.0% | |
| 61 | AGEN | 0.28% | 1,064,250 | $5M | $4.57 | $4M | +564,250 | +112.8% | |
| 62 | FROG | 0.27% | 107,116 | $5M | $43.88 | $489K | -24,500 | -18.6% | |
| 63 | RAPP | 0.24% | 378,469 | $4M | $11.37 | $507K | — | — | |
| 64 | DT | 0.24% | 75,229 | $4M | $55.21 | $17K | -12,500 | -14.2% | |
| 65 | WHWK | 0.22% | 2,082,000 | $4M | $1.87 | $187K | — | — | |
| 66 | EDU | 0.22% | 72,000 | $4M | $53.95 | $84K | -7,500 | -9.4% | |
| 67 | IGMS | 0.21% | 3,255,826 | $4M | $1.12 | -$98K | — | — | |
| 68 | FHTX | 0.19% | 720,720 | $3M | $4.70 | $757K | — | — | |
| 69 | VIGL | 0.19% | 411,191 | $3M | $7.95 | -$232K | -1,555,873 | -79.1% | |
| 70 | NMRA | 0.18% | 4,358,283 | $3M | $0.73 | -$1M | — | — | |
| 71 | PRQR | 0.18% | 1,552,183 | $3M | $2.04 | $1M | — | — | |
| 72 | YNDX | 0.16% | 51,000 | $3M | $55.33 | -$134K | -89,000 | -63.6% | |
| 73 | BDTX | 0.15% | 1,046,517 | $3M | $2.48 | $973K | — | — | |
| 74 | LXEO | 0.14% | 603,435 | $2M | $4.02 | $332K | — | — | |
| 75 | PANW | 0.13% | 11,500 | $2M | $204.64 | $391K | — | — | |
| 76 | QCOM | 0.13% | 14,000 | $2M | $159.26 | $79K | — | — | |
| 77 | WK | 0.11% | 28,000 | $2M | $68.45 | $588K | +10,500 | +60.0% | |
| 78 | ELDN | 0.11% | 690,170 | $2M | $2.71 | -$469K | — | — | |
| 79 | BEKE | 0.11% | 105,000 | $2M | $17.74 | -$247K | — | — | |
| 80 | HUBS | 0.09% | 3,000 | $2M | $556.63 | — | +3,000 | — | NEW |
| 81 | UNH | 0.09% | 5,076 | $2M | $311.97 | — | +5,076 | — | NEW |
| 82 | BIOA | 0.09% | 382,406 | $2M | $4.13 | $141K | — | — | |
| 83 | GTLB | 0.09% | 35,000 | $2M | $45.11 | — | +35,000 | — | NEW |
| 84 | TRML | 0.08% | 91,426 | $1M | $15.99 | $71K | — | — | |
| 85 | RCKT | 0.08% | 591,263 | $1M | $2.45 | -$2M | — | — | |
| 86 | TSLA | 0.07% | 4,000 | $1M | $317.66 | -$1M | -5,000 | -55.6% | |
| 87 | SAIL | 0.06% | 50,000 | $1M | $22.86 | -$638K | -45,000 | -47.4% | |
| 88 | SEMR | 0.06% | 125,000 | $1M | $9.05 | -$35K | — | — | |
| 89 | PRMB | 0.06% | 37,500 | $1M | $29.62 | — | +37,500 | — | NEW |
| 90 | CLBT | 0.05% | 60,000 | $960K | $16.00 | — | +60,000 | — | NEW |
| 91 | KLRS | 0.04% | 282,586 | $755K | $2.67 | -$2M | — | — | |
| 92 | HOOK | 0.04% | 566,640 | $711K | $1.25 | $99K | — | — | |
| 93 | TEAM | 0.04% | 3,500 | $711K | $203.09 | — | +3,500 | — | NEW |
| 94 | PCOR | 0.04% | 10,000 | $684K | $68.42 | $24K | — | — | |
| 95 | CCCS | 0.03% | 50,000 | $470K | $9.41 | — | +50,000 | — | NEW |
| 96 | PCG | 0.02% | 25,000 | $348K | $13.94 | — | +25,000 | — | NEW |
| 97 | RDDT | 0.02% | 2,000 | $301K | $150.57 | -$2M | -21,500 | -91.5% | |
| 98 | VRT | 0.01% | 2,000 | $257K | $128.41 | — | +2,000 | — | NEW |
| 99 | DECK | 0.01% | 2,000 | $206K | $103.07 | -$353K | -3,000 | -60.0% | |
| 100 | CRBU | 0.01% | 105,347 | $133K | $1.26 | $37K | — | — |