Asset Manager
← All Institutions
Siren, L.L.C.
Market Value
$2.4B
+36.2%
Holdings
121
-1
New Purchases
20
Added To
24
Closed
16
Reduced
12
Top 10 Concentration
50.6%
Turnover
29.8%
Top Buys (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| RZLT | 1.91% | 0.00% | +1.91% | $46M |
| ARWR | 3.84% | 2.40% | +1.44% | $92M |
| GPCR | 1.20% | 0.00% | +1.20% | $29M |
| TNGX | 2.06% | 0.98% | +1.08% | $49M |
| RAPP | 1.31% | 0.24% | +1.06% | $31M |
| RCUS | 1.65% | 0.75% | +0.91% | $40M |
| STOK | 2.20% | 1.45% | +0.75% | $53M |
| COGT | 1.03% | 0.35% | +0.68% | $25M |
| BCAX | 3.44% | 2.75% | +0.68% | $82M |
| CNTA | 3.26% | 2.58% | +0.68% | $78M |
| QURE | 0.67% | 0.00% | +0.67% | $16M |
| RYTM | 2.11% | 1.47% | +0.64% | $50M |
| RAPT | 0.62% | 0.00% | +0.62% | $15M |
| RELY | 1.10% | 0.55% | +0.55% | $26M |
| RNAM | 2.34% | 1.79% | +0.54% | $56M |
Top Sells (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| SRRK | 14.37% | 18.61% | -4.24% | $344M |
| MRUS | 0.00% | 2.55% | -2.55% | $0 |
| MLTX | 0.00% | 1.36% | -1.36% | $0 |
| AKRO | 0.00% | 0.97% | -0.97% | $0 |
| IRON | 2.52% | 3.31% | -0.79% | $60M |
| TBLA | 1.42% | 2.07% | -0.65% | $34M |
| PCVX | 0.00% | 0.55% | -0.55% | $0 |
| KYMR | 8.09% | 8.50% | -0.40% | $194M |
| VERA | 0.00% | 0.33% | -0.33% | $0 |
| SLN | 0.63% | 0.96% | -0.33% | $15M |
| AVBP | 0.54% | 0.87% | -0.33% | $13M |
| PCRX | 0.00% | 0.31% | -0.31% | $0 |
| GOOGL | 0.21% | 0.51% | -0.29% | $5M |
| TRVI | 0.97% | 1.22% | -0.26% | $23M |
| WVE | 1.13% | 1.36% | -0.24% | $27M |
Sector Allocation Over Time
Market Cap Concentration
| Tier | Holdings | Value | Weight |
|---|---|---|---|
| Mega Cap | 8 | $45M | 1.9% |
| Large Cap | 31 | $447M | 18.7% |
| Mid Cap | 36 | $1.3B | 53.4% |
| Small Cap | 28 | $526M | 21.9% |
| Micro Cap | 18 | $100M | 4.2% |
Portfolio Analytics
Avg Market Cap
$182.2B
Median Market Cap
$4.1B
Avg P/E
60.2
Median P/E
33.3
Avg Dividend Yield
0.00%
Avg Beta
1.20
# Stocks
121
# ETFs / Funds
0
Top Holdings (121 total)
| # | Symbol | % Port | Shares | Value | Avg Price | Q/Q Value Chg | Share Chg | Chg % | Status |
|---|---|---|---|---|---|---|---|---|---|
| 1 | SRRK | 14.37% | 9,250,005 | $344M | $37.24 | $17M | — | — | |
| 2 | KYMR | 8.09% | 3,428,150 | $194M | $56.60 | $44M | — | — | |
| 3 | ONC | 7.01% | 492,990 | $168M | $340.70 | $45M | -17,000 | -3.3% | |
| 4 | ARWR | 3.84% | 2,669,880 | $92M | $34.49 | $50M | — | — | |
| 5 | BCAX | 3.44% | 5,216,969 | $82M | $15.79 | $34M | — | — | |
| 6 | CNTA | 3.26% | 3,227,517 | $78M | $24.25 | $33M | -232,512 | -6.7% | |
| 7 | CRNX | 2.93% | 1,688,611 | $70M | $41.65 | $22M | — | — | |
| 8 | EWTX | 2.64% | 3,897,099 | $63M | $16.22 | $22M | +736,801 | +23.3% | |
| 9 | IRON | 2.52% | 913,401 | $60M | $66.08 | $2M | -186,000 | -16.9% | |
| 10 | DYN | 2.50% | 4,729,174 | $60M | $12.65 | $14M | -107,263 | -2.2% | |
| 11 | APLS | 2.43% | 2,578,396 | $58M | $22.63 | $14M | — | — | |
| 12 | RNAM | 2.34% | 1,285,610 | $56M | $43.57 | $24M | +175,000 | +15.8% | |
| 13 | STOK | 2.20% | 2,247,347 | $53M | $23.50 | $27M | — | — | |
| 14 | LXRX | 2.19% | 38,918,903 | $53M | $1.35 | $16M | — | — | |
| 15 | RYTM | 2.11% | 499,975 | $50M | $100.99 | $25M | +90,233 | +22.0% | |
| 16 | TNGX | 2.06% | 5,883,188 | $49M | $8.40 | $32M | +2,518,374 | +74.8% | |
| 17 | RVMD | 2.03% | 1,043,720 | $49M | $46.70 | $14M | +104,965 | +11.2% | |
| 18 | RZLT | 1.91% | 4,870,000 | $46M | $9.40 | — | +4,870,000 | — | NEW |
| 19 | SEPN | 1.73% | 2,202,514 | $41M | $18.81 | $18M | — | — | |
| 20 | RCUS | 1.65% | 2,912,077 | $40M | $13.60 | $26M | +1,300,000 | +80.6% | |
| 21 | TSHA | 1.50% | 11,014,737 | $36M | $3.27 | $11M | — | — | |
| 22 | TBLA | 1.42% | 9,969,495 | $34M | $3.41 | -$2M | — | — | |
| 23 | XENE | 1.36% | 812,761 | $33M | $40.15 | $7M | — | — | |
| 24 | RAPP | 1.31% | 1,053,469 | $31M | $29.70 | $27M | +675,000 | +178.3% | |
| 25 | GPCR | 1.20% | 1,026,811 | $29M | $28.00 | — | +1,026,811 | — | NEW |
| 26 | WVE | 1.13% | 3,696,322 | $27M | $7.32 | $3M | — | — | |
| 27 | RELY | 1.10% | 1,618,271 | $26M | $16.30 | $17M | +1,102,822 | +213.9% | |
| 28 | COGT | 1.03% | 1,724,279 | $25M | $14.36 | $19M | +869,900 | +101.8% | |
| 29 | TRVI | 0.97% | 2,536,867 | $23M | $9.15 | $2M | -1,401,926 | -35.6% | |
| 30 | KRRO | 0.84% | 418,833 | $20M | $47.89 | $15M | — | — | |
| 31 | ERAS | 0.80% | 8,757,249 | $19M | $2.18 | $8M | — | — | |
| 32 | IHS | 0.67% | 2,357,520 | $16M | $6.82 | $3M | — | — | |
| 33 | QURE | 0.67% | 275,200 | $16M | $58.37 | — | +275,200 | — | NEW |
| 34 | BCYC | 0.65% | 2,012,752 | $16M | $7.74 | $2M | — | — | |
| 35 | SLN | 0.63% | 2,911,438 | $15M | $5.19 | -$2M | — | — | |
| 36 | RAPT | 0.62% | 580,466 | $15M | $25.79 | — | +580,466 | — | NEW |
| 37 | UPB | 0.62% | 788,450 | $15M | $18.81 | $6M | — | — | |
| 38 | GOSS | 0.57% | 5,208,968 | $14M | $2.63 | $7M | — | — | |
| 39 | AVBP | 0.54% | 700,000 | $13M | $18.45 | -$2M | — | — | |
| 40 | AMZN | 0.54% | 58,500 | $13M | $219.57 | $449K | +2,000 | +3.5% | |
| 41 | ORIC | 0.50% | 1,007,575 | $12M | $12.00 | $2M | — | — | |
| 42 | DNLI | 0.50% | 821,513 | $12M | $14.52 | $435K | — | — | |
| 43 | IONQ | 0.44% | 170,000 | $10M | $61.50 | $3M | — | — | |
| 44 | SION | 0.40% | 325,000 | $10M | $29.41 | $4M | — | — | |
| 45 | CRWD | 0.38% | 18,500 | $9M | $490.38 | -$350K | — | — | |
| 46 | MSFT | 0.37% | 17,150 | $9M | $517.95 | $850K | +1,000 | +6.2% | |
| 47 | SEER | 0.36% | 4,000,000 | $9M | $2.17 | $120K | — | — | |
| 48 | YNDX | 0.34% | 72,600 | $8M | $112.27 | $5M | +21,600 | +42.4% | |
| 49 | NMRA | 0.33% | 4,358,283 | $8M | $1.82 | $5M | — | — | |
| 50 | TSM | 0.33% | 28,200 | $8M | $279.29 | $968K | -2,300 | -7.5% | |
| 51 | CRM | 0.30% | 30,100 | $7M | $237.00 | $971K | +7,500 | +33.2% | |
| 52 | CGEM | 0.30% | 1,193,410 | $7M | $5.93 | -$2M | — | — | |
| 53 | NVDA | 0.29% | 37,485 | $7M | $186.58 | -$903K | -12,500 | -25.0% | |
| 54 | NOW | 0.27% | 7,126 | $7M | $920.28 | $1M | +2,000 | +39.0% | |
| 55 | SYRE | 0.26% | 368,598 | $6M | $16.76 | $660K | — | — | |
| 56 | RNAC | 0.24% | 563,272 | $6M | $10.22 | -$96K | — | — | |
| 57 | PDD | 0.24% | 43,401 | $6M | $132.17 | $200K | -9,500 | -18.0% | |
| 58 | ELDN | 0.22% | 2,072,767 | $5M | $2.59 | $3M | +1,382,597 | +200.3% | |
| 59 | ADBE | 0.22% | 15,051 | $5M | $352.75 | -$514K | — | — | |
| 60 | GOOGL | 0.21% | 21,203 | $5M | $243.10 | -$4M | -29,500 | -58.2% | |
| 61 | FROG | 0.21% | 107,116 | $5M | $47.33 | $370K | — | — | |
| 62 | SGMT | 0.21% | 724,771 | $5M | $6.86 | -$551K | — | — | |
| 63 | DT | 0.20% | 100,229 | $5M | $48.45 | $703K | +25,000 | +33.2% | |
| 64 | DDOG | 0.20% | 32,925 | $5M | $142.40 | -$473K | -5,500 | -14.3% | |
| 65 | IMAB | 0.18% | 1,165,957 | $4M | $3.78 | — | +1,165,957 | — | NEW |
| 66 | AGEN | 0.17% | 1,064,250 | $4M | $3.85 | -$766K | — | — | |
| 67 | LXEO | 0.17% | 603,435 | $4M | $6.64 | $2M | — | — | |
| 68 | BDTX | 0.17% | 1,046,517 | $4M | $3.79 | $1M | — | — | |
| 69 | WHWK | 0.16% | 2,082,000 | $4M | $1.90 | $62K | — | — | |
| 70 | FHTX | 0.15% | 720,720 | $4M | $4.89 | $137K | — | — | |
| 71 | PRQR | 0.14% | 1,552,183 | $3M | $2.13 | $140K | — | — | |
| 72 | EDU | 0.14% | 62,000 | $3M | $53.07 | -$594K | -10,000 | -13.9% | |
| 73 | CRWV | 0.14% | 24,000 | $3M | $136.85 | — | +24,000 | — | NEW |
| 74 | PEPG | 0.13% | 700,000 | $3M | $4.62 | — | +700,000 | — | NEW |
| 75 | GTLB | 0.12% | 64,000 | $3M | $45.08 | $1M | +29,000 | +82.9% | |
| 76 | BEKE | 0.11% | 145,000 | $3M | $19.00 | $892K | +40,000 | +38.1% | |
| 77 | PANW | 0.11% | 13,450 | $3M | $203.62 | $385K | +1,950 | +17.0% | |
| 78 | WK | 0.11% | 30,000 | $3M | $86.08 | $666K | +2,000 | +7.1% | |
| 79 | QCOM | 0.10% | 14,000 | $2M | $166.36 | $99K | — | — | |
| 80 | BIOA | 0.09% | 382,406 | $2M | $5.88 | $669K | — | — | |
| 81 | KDP | 0.08% | 77,050 | $2M | $25.51 | — | +77,050 | — | NEW |
| 82 | HUBS | 0.08% | 4,000 | $2M | $467.80 | $201K | +1,000 | +33.3% | |
| 83 | CMG | 0.08% | 47,500 | $2M | $39.19 | — | +47,500 | — | NEW |
| 84 | KLRS | 0.08% | 318,264 | $2M | $5.78 | $1M | +35,678 | +12.6% | |
| 85 | GBIO | 0.08% | 296,892 | $2M | $6.12 | — | +296,892 | — | NEW |
| 86 | CLBT | 0.07% | 90,000 | $2M | $18.53 | $708K | +30,000 | +50.0% | |
| 87 | PRMB | 0.07% | 75,000 | $2M | $22.10 | $547K | +37,500 | +100.0% | |
| 88 | SPOT | 0.06% | 2,173 | $2M | $698.00 | — | +2,173 | — | NEW |
| 89 | MNDY | 0.06% | 7,000 | $1M | $193.69 | — | +7,000 | — | NEW |
| 90 | SAIL | 0.05% | 50,000 | $1M | $22.08 | -$39K | — | — | |
| 91 | ESTC | 0.04% | 12,500 | $1M | $84.49 | — | +12,500 | — | NEW |
| 92 | IREN | 0.04% | 20,000 | $938K | $46.91 | — | +20,000 | — | NEW |
| 93 | SEMR | 0.04% | 125,000 | $885K | $7.08 | -$246K | — | — | |
| 94 | PINS | 0.03% | 25,000 | $804K | $32.17 | — | +25,000 | — | NEW |
| 95 | FIG | 0.03% | 15,000 | $778K | $51.87 | — | +15,000 | — | NEW |
| 96 | CFLT | 0.03% | 37,500 | $742K | $19.80 | — | +37,500 | — | NEW |
| 97 | PCOR | 0.03% | 10,000 | $729K | $72.92 | $45K | — | — | |
| 98 | ALAB | 0.03% | 3,500 | $685K | $195.80 | — | +3,500 | — | NEW |
| 99 | TSLA | 0.03% | 1,500 | $667K | $444.72 | -$604K | -2,500 | -62.5% | |
| 100 | CHYM | 0.02% | 25,000 | $504K | $20.17 | — | +25,000 | — | NEW |