Asset Manager
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DAFNA Capital Management LLC
Market Value
$522M
+23.4%
Holdings
93
+13
New Purchases
17
Added To
17
Closed
7
Reduced
26
Top 10 Concentration
56.5%
Turnover
25.8%
Top Buys (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| RVMD | 20.19% | 13.35% | +6.84% | $105M |
| ASND | 2.48% | 0.00% | +2.48% | $13M |
| CMPS | 5.45% | 3.16% | +2.29% | $28M |
| DNLI | 3.64% | 1.45% | +2.20% | $19M |
| NKTR | 4.26% | 2.81% | +1.45% | $22M |
| PODD | 1.80% | 0.54% | +1.27% | $9M |
| EWTX | 1.77% | 0.84% | +0.93% | $9M |
| KYMR | 0.59% | 0.00% | +0.59% | $3M |
| ANL | 0.53% | 0.00% | +0.53% | $3M |
| NGEN | 0.41% | 0.00% | +0.41% | $2M |
| MPLT | 1.17% | 0.82% | +0.35% | $6M |
| RCUS | 2.61% | 2.27% | +0.34% | $14M |
| KIDS | 0.69% | 0.36% | +0.33% | $4M |
| RNA | 0.33% | 0.00% | +0.33% | $2M |
| EPRX | 0.29% | 0.00% | +0.29% | $1M |
Top Sells (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| DAWN | 0.00% | 4.96% | -4.96% | $0 |
| XBI | 5.96% | 9.62% | -3.66% | $31M |
| STXS | 4.51% | 5.95% | -1.44% | $24M |
| BHVN | 0.39% | 1.69% | -1.30% | $2M |
| KALV | 0.00% | 1.27% | -1.27% | $0 |
| MBX | 0.12% | 1.24% | -1.11% | $652K |
| LRMR | 1.17% | 2.16% | -0.98% | $6M |
| IBB | 1.55% | 2.48% | -0.93% | $8M |
| ATRC | 3.20% | 4.03% | -0.83% | $17M |
| TNDM | 1.03% | 1.61% | -0.58% | $5M |
| CYTK | 2.81% | 3.39% | -0.58% | $15M |
| XENE | 2.90% | 3.45% | -0.55% | $15M |
| FULC | 0.00% | 0.37% | -0.37% | $0 |
| BCAX | 1.62% | 1.98% | -0.36% | $8M |
| NBIX | 1.87% | 2.20% | -0.33% | $10M |
Sector Allocation Over Time
Market Cap Concentration
| Tier | Holdings | Value | Weight |
|---|---|---|---|
| Large Cap | 7 | $145M | 27.8% |
| Mid Cap | 20 | $183M | 35.0% |
| Small Cap | 37 | $137M | 26.3% |
| Micro Cap | 29 | $57M | 10.9% |
Portfolio Analytics
Avg Market Cap
$3.0B
Median Market Cap
$945M
Avg P/E
50.7
Median P/E
22.4
Avg Dividend Yield
—%
Avg Beta
1.06
# Stocks
91
# ETFs / Funds
2
Top Holdings (93 total)
| # | Symbol | % Port | Shares | Value | Avg Price | Q/Q Value Chg | Share Chg | Chg % | Status |
|---|---|---|---|---|---|---|---|---|---|
| 1 | RVMD | 20.19% | 562,630 | $105M | $187.28 | $49M | -18,048 | -3.1% | |
| 2 | XBI | 5.96% | 196,505 | $31M | $158.25 | -$10M | -122,000 | -38.3% | |
| 3 | CMPS | 5.45% | 2,011,952 | $28M | $14.15 | $15M | -406,930 | -16.8% | |
| 4 | STXS | 4.51% | 13,680,554 | $24M | $1.72 | -$2M | — | — | |
| 5 | NKTR | 4.26% | 318,380 | $22M | $69.81 | $10M | +153,202 | +92.8% | |
| 6 | DNLI | 3.64% | 739,014 | $19M | $25.72 | $13M | +420,514 | +132.0% | |
| 7 | IDYA | 3.55% | 497,240 | $19M | $37.27 | $3M | +20,500 | +4.3% | |
| 8 | ATRC | 3.20% | 597,431 | $17M | $27.98 | -$329K | — | — | |
| 9 | XENE | 2.90% | 250,772 | $15M | $60.36 | $554K | — | — | |
| 10 | CYTK | 2.81% | 171,998 | $15M | $85.19 | $317K | -45,499 | -20.9% | |
| 11 | RCUS | 2.61% | 441,829 | $14M | $30.83 | $4M | -2,000 | -0.5% | |
| 12 | ASND | 2.48% | 48,469 | $13M | $266.72 | — | +48,469 | — | NEW |
| 13 | NBIX | 1.87% | 57,769 | $10M | $168.53 | $433K | -12,846 | -18.2% | |
| 14 | AXGN | 1.85% | 208,960 | $10M | $46.19 | $1M | -41,000 | -16.4% | |
| 15 | PODD | 1.80% | 61,870 | $9M | $152.25 | $7M | +51,000 | +469.2% | |
| 16 | EWTX | 1.77% | 226,819 | $9M | $40.63 | $6M | +114,583 | +102.1% | |
| 17 | BCAX | 1.62% | 284,955 | $8M | $29.69 | $72K | -136,778 | -32.4% | |
| 18 | IBB | 1.55% | 42,595 | $8M | $190.19 | -$2M | -19,500 | -31.4% | |
| 19 | SNDX | 1.40% | 335,255 | $7M | $21.86 | $2M | +117,900 | +54.2% | |
| 20 | MPLT | 1.17% | 171,006 | $6M | $35.84 | $3M | — | — | |
| 21 | LRMR | 1.17% | 2,008,164 | $6M | $3.05 | -$3M | -21,000 | -1.0% | |
| 22 | IPSC | 1.13% | 2,400,458 | $6M | $2.45 | $379K | -33,895 | -1.4% | |
| 23 | DXCM | 1.11% | 86,279 | $6M | $67.35 | $393K | — | — | |
| 24 | IMVT | 1.10% | 149,524 | $6M | $38.53 | $2M | -1,000 | -0.7% | |
| 25 | INGN | 1.04% | 845,179 | $5M | $6.45 | $228K | — | — | |
| 26 | TNDM | 1.03% | 355,208 | $5M | $15.09 | -$1M | — | — | |
| 27 | ALKS | 1.02% | 101,266 | $5M | $52.39 | $374K | -38,216 | -27.4% | |
| 28 | STOK | 0.82% | 130,875 | $4M | $32.72 | $21K | — | — | |
| 29 | ALLO | 0.80% | 2,000,000 | $4M | $2.08 | $817K | +629,882 | +46.0% | |
| 30 | BCRX | 0.77% | 400,248 | $4M | $10.00 | -$93K | -30,000 | -7.0% | |
| 31 | LKFT | 0.75% | 130,175 | $4M | $29.98 | -$3K | — | — | |
| 32 | KIDS | 0.69% | 189,130 | $4M | $19.13 | $2M | +93,471 | +97.7% | |
| 33 | HELP | 0.65% | 514,061 | $3M | $6.61 | $1M | +15,700 | +3.1% | |
| 34 | RAPP | 0.60% | 75,000 | $3M | $41.67 | $778K | — | — | |
| 35 | KYMR | 0.59% | 27,000 | $3M | $114.67 | — | +27,000 | — | NEW |
| 36 | PRQR | 0.55% | 1,530,361 | $3M | $1.86 | $307K | -37,200 | -2.4% | |
| 37 | NGNE | 0.54% | 89,032 | $3M | $31.45 | $2M | +32,397 | +57.2% | |
| 38 | ANL | 0.53% | 239,553 | $3M | $11.50 | — | +239,553 | — | NEW |
| 39 | PRCT | 0.52% | 120,000 | $3M | $22.58 | -$292K | — | — | |
| 40 | AQST | 0.51% | 645,915 | $3M | $4.16 | $1M | +277,500 | +75.3% | |
| 41 | CLDX | 0.49% | 68,518 | $3M | $37.21 | $376K | — | — | |
| 42 | GPCR | 0.48% | 46,500 | $2M | $53.67 | $254K | — | — | |
| 43 | ALGN | 0.45% | 14,000 | $2M | $168.66 | -$210K | -1,000 | -6.7% | |
| 44 | VKTX | 0.44% | 59,516 | $2M | $39.01 | $385K | — | — | |
| 45 | NGEN | 0.41% | 1,050,000 | $2M | $2.06 | — | +1,050,000 | — | NEW |
| 46 | BHVN | 0.39% | 137,593 | $2M | $14.88 | -$5M | -708,142 | -83.7% | |
| 47 | MAZE | 0.37% | 65,000 | $2M | $29.84 | $895K | +30,000 | +85.7% | |
| 48 | ALEC | 0.35% | 908,351 | $2M | $2.01 | -$127K | — | — | |
| 49 | LXEO | 0.34% | 377,059 | $2M | $4.66 | -$409K | — | — | |
| 50 | PROF | 0.33% | 260,360 | $2M | $6.65 | $27K | -2,645 | -1.0% | |
| 51 | RNA | 0.33% | 128,000 | $2M | $13.45 | — | +128,000 | — | NEW |
| 52 | ANNX | 0.33% | 297,812 | $2M | $5.71 | $1M | +180,000 | +152.8% | |
| 53 | CTMX | 0.31% | 438,407 | $2M | $3.75 | $563K | +208,407 | +90.6% | |
| 54 | RARE | 0.30% | 47,100 | $2M | $33.39 | $293K | -14,000 | -22.9% | |
| 55 | EPRX | 0.29% | 225,600 | $1M | $6.61 | — | +225,600 | — | NEW |
| 56 | DSGN | 0.28% | 102,600 | $1M | $14.47 | — | +102,600 | — | NEW |
| 57 | FATE | 0.27% | 525,000 | $1M | $2.70 | $758K | -25,000 | -4.5% | |
| 58 | KURA | 0.25% | 120,568 | $1M | $10.97 | -$595K | -115,300 | -48.9% | |
| 59 | SBTX | 0.25% | 164,285 | $1M | $8.01 | $197K | +25,000 | +17.9% | |
| 60 | MLYS | 0.23% | 44,490 | $1M | $26.98 | $158K | +6,000 | +15.6% | |
| 61 | IMTX | 0.23% | 116,960 | $1M | $10.13 | -$1M | -108,900 | -48.2% | |
| 62 | TELA | 0.21% | 1,441,029 | $1M | $0.75 | $187K | — | — | |
| 63 | CRBP | 0.19% | 107,773 | $1M | $9.38 | — | +107,773 | — | NEW |
| 64 | INSP | 0.16% | 18,200 | $812K | $44.61 | -$127K | — | — | |
| 65 | ACET | 0.16% | 93,812 | $811K | $8.64 | $172K | — | — | |
| 66 | SPTX | 0.13% | 32,400 | $704K | $21.72 | — | +32,400 | — | NEW |
| 67 | MBX | 0.12% | 11,809 | $652K | $55.20 | -$5M | -163,656 | -93.3% | |
| 68 | BNTX | 0.12% | 7,000 | $651K | $93.05 | $29K | — | — | |
| 69 | ARTV | 0.12% | 67,101 | $651K | $9.70 | — | +67,101 | — | NEW |
| 70 | PLRX | 0.11% | 487,000 | $555K | $1.14 | -$58K | — | — | |
| 71 | SCYX | 0.11% | 135,868 | $553K | $4.07 | — | +135,868 | — | NEW |
| 72 | EDIT | 0.11% | 170,470 | $552K | $3.24 | — | +170,470 | — | NEW |
| 73 | OBIO | 0.10% | 126,841 | $547K | $4.32 | $8K | — | — | |
| 74 | FHTX | 0.10% | 111,859 | $546K | $4.88 | $11K | — | — | |
| 75 | ARAY | 0.08% | 1,680,508 | $433K | $0.26 | -$219K | — | — | |
| 76 | QTTB | 0.08% | 32,896 | $419K | $12.74 | — | +32,896 | — | NEW |
| 77 | NVCT | 0.07% | 20,000 | $368K | $18.39 | — | +20,000 | — | NEW |
| 78 | CGEN | 0.07% | 168,232 | $360K | $2.14 | -$189K | -89,551 | -34.7% | |
| 79 | IBIO | 0.06% | 170,053 | $298K | $1.75 | -$70K | -23,585 | -12.2% | |
| 80 | AUTL | 0.05% | 179,316 | $287K | $1.60 | $39K | — | — | |
| 81 | BCYC | 0.05% | 64,492 | $273K | $4.24 | -$26K | — | — | |
| 82 | TNYA | 0.04% | 300,000 | $222K | $0.74 | — | +300,000 | — | NEW |
| 83 | VRCA | 0.03% | 23,750 | $145K | $6.12 | -$668K | -129,962 | -84.5% | |
| 84 | ENGN | 0.02% | 74,650 | $129K | $1.73 | — | +74,650 | — | NEW |
| 85 | KARD | 0.02% | 5,000 | $119K | $23.85 | — | +5,000 | — | NEW |
| 86 | ADCT | 0.02% | 77,081 | $82K | $1.07 | -$188K | +5,000 | +6.9% | |
| 87 | NMRA | —% | — | — | — | -$136K | -70,000 | -100.0% | SOLD |
| 88 | ORIC | —% | — | — | — | -$945K | -98,724 | -100.0% | SOLD |
| 89 | KALV | —% | — | — | — | -$5M | -267,402 | -100.0% | SOLD |
| 90 | KPTI | —% | — | — | — | -$255K | -45,800 | -100.0% | SOLD |
| 91 | FULC | —% | — | — | — | -$2M | -205,000 | -100.0% | SOLD |
| 92 | DAWN | —% | — | — | — | -$21M | -978,463 | -100.0% | SOLD |
| 93 | ZBIO | —% | — | — | — | -$831K | -42,500 | -100.0% | SOLD |