Asset Manager
← All Institutions
RTW INVESTMENTS, LP
Market Value
$11.4B
+14.5%
Holdings
93
New Purchases
9
Added To
25
Closed
13
Reduced
8
Top 10 Concentration
49.2%
Turnover
23.7%
Top Buys (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| KLRA | 2.09% | 0.00% | +2.09% | $237M |
| ORKA | 2.63% | 1.02% | +1.61% | $299M |
| RARE | 2.29% | 0.77% | +1.52% | $260M |
| SYRE | 3.32% | 2.12% | +1.20% | $377M |
| TNGX | 3.83% | 2.81% | +1.02% | $435M |
| GPCR | 0.76% | 0.00% | +0.76% | $86M |
| CMPS | 1.33% | 0.59% | +0.74% | $151M |
| GH | 1.96% | 1.38% | +0.58% | $222M |
| ARGX | 5.80% | 5.22% | +0.57% | $658M |
| GHRS | 1.40% | 0.84% | +0.56% | $160M |
| CGON | 5.33% | 4.77% | +0.56% | $605M |
| ESTA | 2.01% | 1.52% | +0.49% | $228M |
| NBIX | 1.88% | 1.41% | +0.47% | $214M |
| AXGN | 0.41% | 0.00% | +0.41% | $47M |
| DHR | 0.39% | 0.00% | +0.39% | $44M |
Top Sells (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| INSM | 4.55% | 7.99% | -3.44% | $516M |
| APGE | 0.00% | 2.36% | -2.36% | $0 |
| APLS | 0.00% | 1.50% | -1.50% | $0 |
| COGT | 0.79% | 2.12% | -1.33% | $89M |
| MDGL | 9.43% | 10.52% | -1.10% | $1.1B |
| ISRG | 0.00% | 1.02% | -1.02% | $0 |
| CNTA | 0.00% | 0.82% | -0.82% | $0 |
| CRNX | 0.00% | 0.53% | -0.53% | $0 |
| TARS | 1.86% | 2.37% | -0.51% | $211M |
| CELC | 3.04% | 3.50% | -0.45% | $346M |
| WAY | 0.00% | 0.40% | -0.40% | $0 |
| HNGE | 0.37% | 0.75% | -0.39% | $42M |
| ARWR | 0.00% | 0.37% | -0.37% | $0 |
| SYK | 0.00% | 0.33% | -0.33% | $0 |
| STOK | 1.62% | 1.85% | -0.23% | $184M |
Sector Allocation Over Time
Market Cap Concentration
| Tier | Holdings | Value | Weight |
|---|---|---|---|
| Large Cap | 11 | $3.2B | 27.9% |
| Mid Cap | 36 | $5.6B | 49.7% |
| Small Cap | 35 | $2.4B | 21.2% |
| Micro Cap | 11 | $139M | 1.2% |
Portfolio Analytics
Avg Market Cap
$9.2B
Median Market Cap
$2.0B
Avg P/E
80.3
Median P/E
40.1
Avg Dividend Yield
0.01%
Avg Beta
0.93
# Stocks
93
# ETFs / Funds
0
Top Holdings (93 total)
| # | Symbol | % Port | Shares | Value | Avg Price | Q/Q Value Chg | Share Chg | Chg % | Status |
|---|---|---|---|---|---|---|---|---|---|
| 1 | MDGL | 9.43% | 1,993,687 | $1.1B | $536.95 | $27M | — | — | |
| 2 | ARGX | 5.80% | 709,446 | $658M | $927.77 | $140M | — | — | |
| 3 | PTCT | 5.56% | 7,746,415 | $632M | $81.57 | $104M | — | — | |
| 4 | PTGX | 5.46% | 5,061,175 | $620M | $122.58 | $87M | +2,122 | +0.0% | |
| 5 | CGON | 5.33% | 8,514,590 | $605M | $71.05 | $132M | +1,529,782 | +21.9% | |
| 6 | INSM | 4.55% | 4,842,880 | $516M | $106.62 | -$276M | — | — | |
| 7 | TNGX | 3.83% | 13,900,620 | $435M | $31.26 | $156M | +600,000 | +4.5% | |
| 8 | SYRE | 3.32% | 4,251,996 | $377M | $88.78 | $167M | +80,000 | +1.9% | |
| 9 | CELC | 3.04% | 3,304,903 | $346M | $104.62 | -$1M | +265,282 | +8.7% | |
| 10 | ERAS | 2.90% | 17,946,754 | $329M | $18.32 | $67M | +1,789,579 | +11.1% | |
| 11 | RDNT | 2.63% | 4,846,958 | $299M | $61.67 | $59M | +561,958 | +13.1% | |
| 12 | ORKA | 2.63% | 3,139,030 | $299M | $95.17 | $198M | +1,080,882 | +52.5% | |
| 13 | NTRA | 2.39% | 1,000,000 | $271M | $271.45 | $21M | -250,000 | -20.0% | |
| 14 | RARE | 2.29% | 7,796,895 | $260M | $33.39 | $184M | +4,148,100 | +113.7% | |
| 15 | IRTC | 2.29% | 2,182,631 | $260M | $118.95 | $63M | +514,131 | +30.8% | |
| 16 | CYTK | 2.15% | 2,862,003 | $244M | $85.19 | $64M | +140,845 | +5.2% | |
| 17 | KLRA | 2.09% | 10,776,820 | $237M | $22.03 | — | +10,776,820 | — | NEW |
| 18 | ESTA | 2.01% | 2,655,695 | $228M | $85.81 | $77M | — | — | |
| 19 | GH | 1.96% | 1,481,033 | $222M | $150.03 | $85M | — | — | |
| 20 | NBIX | 1.88% | 1,267,925 | $214M | $168.54 | $74M | +205,853 | +19.4% | |
| 21 | TARS | 1.86% | 3,357,059 | $211M | $62.94 | -$23M | +11,034 | +0.3% | |
| 22 | STOK | 1.62% | 5,623,525 | $184M | $32.72 | $900K | — | — | |
| 23 | ACAD | 1.59% | 7,144,524 | $181M | $25.30 | $22M | — | — | |
| 24 | RGEN | 1.49% | 1,240,637 | $169M | $136.44 | $27M | +34,637 | +2.9% | |
| 25 | GHRS | 1.40% | 5,933,815 | $160M | $26.88 | $76M | — | — | |
| 26 | IMCR | 1.36% | 4,869,798 | $155M | $31.75 | $8M | — | — | |
| 27 | CMPS | 1.33% | 10,700,974 | $151M | $14.15 | $93M | +68,584 | +0.7% | |
| 28 | IMTX | 1.15% | 12,946,176 | $131M | $10.13 | $5M | +76,836 | +0.6% | |
| 29 | ZLAB | 1.10% | 6,574,032 | $125M | $19.00 | $1M | — | — | |
| 30 | IMVT | 1.08% | 3,177,849 | $122M | $38.53 | $44M | — | — | |
| 31 | BLTE | 0.97% | 715,332 | $110M | $153.98 | -$4M | — | — | |
| 32 | XNCR | 0.96% | 6,777,461 | $109M | $16.10 | $27M | — | — | |
| 33 | TSHA | 0.81% | 13,560,258 | $92M | $6.81 | $31M | -119,990 | -0.9% | |
| 34 | COGT | 0.79% | 2,309,021 | $89M | $38.70 | -$121M | -3,149,654 | -57.7% | |
| 35 | ALKS | 0.77% | 1,672,356 | $88M | $52.40 | $28M | — | — | |
| 36 | GPCR | 0.76% | 1,607,507 | $86M | $53.67 | — | +1,607,507 | — | NEW |
| 37 | REPL | 0.72% | 7,411,581 | $82M | $11.07 | $26M | +54,665 | +0.7% | |
| 38 | CSTL | 0.58% | 2,778,335 | $66M | $23.85 | -$1M | +20,000 | +0.7% | |
| 39 | CADL | 0.58% | 6,422,018 | $66M | $10.30 | $35M | — | — | |
| 40 | RCKT | 0.53% | 17,687,772 | $60M | $3.42 | -$3M | — | — | |
| 41 | KOD | 0.51% | 1,487,934 | $58M | $38.96 | $1M | — | — | |
| 42 | AKTS | 0.45% | 1,592,043 | $51M | $32.23 | $23M | — | — | |
| 43 | AXGN | 0.41% | 1,011,576 | $47M | $46.19 | — | +1,011,576 | — | NEW |
| 44 | DHR | 0.39% | 230,000 | $44M | $190.48 | — | +230,000 | — | NEW |
| 45 | CGEM | 0.38% | 2,364,347 | $43M | $18.21 | $19M | +658,387 | +38.6% | |
| 46 | NGNE | 0.38% | 1,362,456 | $43M | $31.45 | $15M | — | — | |
| 47 | HNGE | 0.37% | 500,000 | $42M | $83.00 | -$33M | -1,430,000 | -74.1% | |
| 48 | OBIO | 0.36% | 9,556,063 | $41M | $4.32 | $6M | +1,250,000 | +15.1% | |
| 49 | SLDB | 0.34% | 3,892,926 | $39M | $9.99 | — | +3,892,926 | — | NEW |
| 50 | SVRA | 0.32% | 5,952,380 | $37M | $6.16 | $4M | — | — | |
| 51 | AQST | 0.27% | 7,426,471 | $31M | $4.16 | $74K | — | — | |
| 52 | KYMR | 0.24% | 240,000 | $28M | $114.67 | $8M | — | — | |
| 53 | VSTM | 0.22% | 6,635,793 | $25M | $3.82 | -$10M | +59,487 | +0.9% | |
| 54 | DNTH | 0.21% | 248,063 | $24M | $97.48 | $3M | — | — | |
| 55 | BBNX | 0.21% | 1,500,000 | $24M | $15.67 | $3M | -500,000 | -25.0% | |
| 56 | IPSC | 0.19% | 8,695,652 | $21M | $2.45 | $2M | — | — | |
| 57 | EVMN | 0.18% | 1,502,235 | $20M | $13.29 | -$15M | — | — | |
| 58 | BEAM | 0.17% | 570,394 | $20M | $34.32 | $6M | — | — | |
| 59 | DFTX | 0.17% | 400,000 | $19M | $47.04 | $13M | +100,000 | +33.3% | |
| 60 | IDYA | 0.12% | 370,370 | $14M | $37.27 | — | +370,370 | — | NEW |
| 61 | ATAI | 0.09% | 2,000,000 | $11M | $5.27 | $3M | — | — | |
| 62 | MIST | 0.09% | 7,833,336 | $10M | $1.34 | $3M | +1,502,335 | +23.7% | |
| 63 | OCGN | 0.09% | 6,666,666 | $10M | $1.53 | -$2M | — | — | |
| 64 | TENX | 0.09% | 696,570 | $10M | $14.55 | $4M | +326,324 | +88.1% | |
| 65 | HTFL | 0.08% | 295,000 | $9M | $29.34 | -$3M | -200,000 | -40.4% | |
| 66 | PCSC | 0.07% | 742,500 | $8M | $10.88 | -$67K | — | — | |
| 67 | LRMR | 0.07% | 2,565,999 | $8M | $3.05 | $1M | +1,065,999 | +71.1% | |
| 68 | LMRI | 0.06% | 650,000 | $7M | $11.28 | $2M | — | — | |
| 69 | ALLO | 0.06% | 3,250,000 | $7M | $2.08 | — | +3,250,000 | — | NEW |
| 70 | CBIO | 0.06% | 372,856 | $7M | $18.00 | -$138K | — | — | |
| 71 | FDMT | 0.06% | 475,737 | $6M | $13.30 | $2M | — | — | |
| 72 | MAZE | 0.06% | 212,000 | $6M | $29.84 | — | +212,000 | — | NEW |
| 73 | CAPR | 0.05% | 250,000 | $6M | $24.08 | -$2M | — | — | |
| 74 | KLRS | 0.05% | 1,300,000 | $5M | $4.07 | -$2M | — | — | |
| 75 | ABVX | 0.03% | 26,400 | $4M | $133.26 | — | +26,400 | — | NEW |
| 76 | AVTX | 0.03% | 175,000 | $3M | $18.48 | -$10M | -681,962 | -79.6% | |
| 77 | MDLN | 0.02% | 70,000 | $3M | $39.44 | -$354K | — | — | |
| 78 | IRON | 0.02% | 30,000 | $2M | $73.14 | $276K | — | — | |
| 79 | IMA | 0.02% | 334,445 | $2M | $5.90 | $301K | — | — | |
| 80 | XGN | 0.01% | 195,000 | $907K | $4.65 | -$279K | -200,231 | -50.7% | |
| 81 | SYK | —% | — | — | — | -$33M | -100,000 | -100.0% | SOLD |
| 82 | IVA | —% | — | — | — | -$7M | -1,298,702 | -100.0% | SOLD |
| 83 | CRNX | —% | — | — | — | -$53M | -1,451,326 | -100.0% | SOLD |
| 84 | JBIO | —% | — | — | — | -$8M | -573,205 | -100.0% | SOLD |
| 85 | FLGT | —% | — | — | — | -$20M | -1,289,000 | -100.0% | SOLD |
| 86 | ARWR | —% | — | — | — | -$37M | -585,682 | -100.0% | SOLD |
| 87 | OMDA | —% | — | — | — | -$3M | -200,000 | -100.0% | SOLD |
| 88 | ISRG | —% | — | — | — | -$101M | -220,000 | -100.0% | SOLD |
| 89 | APGE | —% | — | — | — | -$234M | -2,782,097 | -100.0% | SOLD |
| 90 | CNTA | —% | — | — | — | -$82M | -2,054,175 | -100.0% | SOLD |
| 91 | CMPX | —% | — | — | — | -$22M | -4,186,599 | -100.0% | SOLD |
| 92 | APLS | —% | — | — | — | -$148M | -3,685,045 | -100.0% | SOLD |
| 93 | WAY | —% | — | — | — | -$39M | -1,630,000 | -100.0% | SOLD |