Asset Manager
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RTW INVESTMENTS, LP
Market Value
$9.7B
+25.7%
Holdings
96
+19
New Purchases
27
Added To
18
Closed
12
Reduced
11
Top 10 Concentration
51.7%
Turnover
40.6%
Top Buys (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| INSM | 8.65% | 5.73% | +2.92% | $843M |
| IRTC | 2.15% | 0.00% | +2.15% | $210M |
| COGT | 2.77% | 0.64% | +2.13% | $270M |
| APLS | 1.98% | 0.00% | +1.98% | $193M |
| RGEN | 1.79% | 0.00% | +1.79% | $174M |
| PODD | 0.95% | 0.00% | +0.95% | $92M |
| BLTE | 1.17% | 0.30% | +0.88% | $114M |
| CSTL | 0.84% | 0.00% | +0.84% | $82M |
| IMVT | 0.83% | 0.00% | +0.83% | $81M |
| APGE | 2.10% | 1.39% | +0.71% | $205M |
| SYRE | 1.40% | 0.78% | +0.62% | $137M |
| ESTA | 1.94% | 1.37% | +0.57% | $189M |
| CELC | 0.56% | 0.00% | +0.56% | $55M |
| KOD | 0.43% | 0.00% | +0.43% | $42M |
| ARWR | 0.40% | 0.00% | +0.40% | $39M |
Top Sells (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| RNAM | 0.00% | 6.39% | -6.39% | $0 |
| AKRO | 0.00% | 3.35% | -3.35% | $0 |
| MRUS | 0.00% | 2.46% | -2.46% | $0 |
| SYK | 0.88% | 2.34% | -1.45% | $86M |
| NTRA | 3.53% | 4.15% | -0.63% | $344M |
| DGX | 0.00% | 0.61% | -0.61% | $0 |
| ARGX | 5.81% | 6.41% | -0.59% | $566M |
| ISRG | 0.59% | 1.17% | -0.58% | $57M |
| RARE | 0.71% | 1.26% | -0.56% | $69M |
| IMCR | 1.73% | 2.28% | -0.55% | $169M |
| LENZ | 0.00% | 0.52% | -0.52% | $0 |
| DYN | 0.00% | 0.47% | -0.47% | $0 |
| PTGX | 4.53% | 4.93% | -0.40% | $442M |
| MASI | 0.91% | 1.30% | -0.39% | $89M |
| ABVX | 0.00% | 0.38% | -0.38% | $0 |
Sector Allocation Over Time
Market Cap Concentration
| Tier | Holdings | Value | Weight |
|---|---|---|---|
| Large Cap | 16 | $3.8B | 39.3% |
| Mid Cap | 36 | $4.1B | 42.5% |
| Small Cap | 30 | $1.6B | 16.8% |
| Micro Cap | 14 | $141M | 1.4% |
Portfolio Analytics
Avg Market Cap
$8.9B
Median Market Cap
$3.0B
Avg P/E
75.2
Median P/E
40.1
Avg Dividend Yield
0.00%
Avg Beta
0.95
# Stocks
96
# ETFs / Funds
0
Top Holdings (96 total)
| # | Symbol | % Port | Shares | Value | Avg Price | Q/Q Value Chg | Share Chg | Chg % | Status |
|---|---|---|---|---|---|---|---|---|---|
| 1 | MDGL | 11.91% | 1,993,687 | $1.2B | $582.34 | $247M | — | — | |
| 2 | INSM | 8.65% | 4,842,879 | $843M | $174.04 | $399M | +1,758,321 | +57.0% | |
| 3 | PTCT | 6.04% | 7,746,415 | $588M | $75.96 | $113M | — | — | |
| 4 | ARGX | 5.81% | 673,497 | $566M | $840.95 | $70M | — | — | |
| 5 | PTGX | 4.53% | 5,059,053 | $442M | $87.34 | $59M | -697,224 | -12.1% | |
| 6 | NTRA | 3.53% | 1,500,000 | $344M | $229.09 | $22M | -500,000 | -25.0% | |
| 7 | RDNT | 2.88% | 3,938,500 | $281M | $71.35 | $66M | +1,122,956 | +39.9% | |
| 8 | TARS | 2.80% | 3,335,320 | $273M | $81.88 | $84M | +157,884 | +5.0% | |
| 9 | COGT | 2.77% | 7,592,241 | $270M | $35.52 | $220M | +4,124,755 | +119.0% | |
| 10 | PEN | 2.76% | 866,499 | $269M | $310.91 | $50M | — | — | |
| 11 | IRTC | 2.15% | 1,181,990 | $210M | $177.44 | — | +1,181,990 | — | NEW |
| 12 | APGE | 2.10% | 2,712,097 | $205M | $75.48 | $97M | — | — | |
| 13 | APLS | 1.98% | 7,666,764 | $193M | $25.12 | — | +7,666,764 | — | NEW |
| 14 | ACAD | 1.96% | 7,144,524 | $191M | $26.71 | $38M | — | — | |
| 15 | ESTA | 1.94% | 2,588,831 | $189M | $72.88 | $83M | — | — | |
| 16 | STOK | 1.81% | 5,546,856 | $176M | $31.74 | $56M | +423,331 | +8.3% | |
| 17 | RGEN | 1.79% | 1,064,000 | $174M | $163.86 | — | +1,064,000 | — | NEW |
| 18 | CYTK | 1.77% | 2,721,158 | $173M | $63.54 | $23M | — | — | |
| 19 | IMCR | 1.73% | 4,869,798 | $169M | $34.71 | -$8M | — | — | |
| 20 | AXSM | 1.66% | 888,001 | $162M | $182.64 | $26M | -230,882 | -20.6% | |
| 21 | GH | 1.55% | 1,481,033 | $151M | $102.14 | $59M | — | — | |
| 22 | NBIX | 1.55% | 1,062,072 | $151M | $141.83 | $2M | — | — | |
| 23 | SYRE | 1.40% | 4,171,996 | $137M | $32.76 | $76M | +550,000 | +15.2% | |
| 24 | ZLAB | 1.26% | 6,959,032 | $123M | $17.64 | $45M | +4,667,660 | +203.7% | |
| 25 | IMTX | 1.23% | 11,433,354 | $120M | $10.50 | $45M | +2,617,737 | +29.7% | |
| 26 | BLTE | 1.17% | 715,332 | $114M | $159.96 | $91M | +402,832 | +128.9% | |
| 27 | XNCR | 1.06% | 6,777,461 | $104M | $15.31 | $31M | +556,407 | +8.9% | |
| 28 | PODD | 0.95% | 324,600 | $92M | $284.24 | — | +324,600 | — | NEW |
| 29 | TSHA | 0.93% | 16,398,297 | $90M | $5.50 | $11M | -7,955,994 | -32.7% | |
| 30 | MASI | 0.91% | 683,294 | $89M | $130.06 | -$12M | — | — | |
| 31 | SYK | 0.88% | 245,000 | $86M | $351.47 | -$95M | -245,000 | -50.0% | |
| 32 | CGON | 0.86% | 2,012,127 | $84M | $41.52 | $15M | +310,911 | +18.3% | |
| 33 | CSTL | 0.84% | 2,115,237 | $82M | $38.90 | — | +2,115,237 | — | NEW |
| 34 | IMVT | 0.83% | 3,177,850 | $81M | $25.42 | — | +3,177,850 | — | NEW |
| 35 | BBNX | 0.78% | 2,500,000 | $76M | $30.47 | $11M | -799,191 | -24.2% | |
| 36 | GHRS | 0.77% | 5,933,815 | $75M | $12.70 | -$4M | +364,251 | +6.5% | |
| 37 | REPL | 0.71% | 7,140,352 | $69M | $9.72 | $43M | +744,620 | +11.6% | |
| 38 | RARE | 0.71% | 3,000,139 | $69M | $23.00 | -$29M | -258,127 | -7.9% | |
| 39 | CRNX | 0.65% | 1,351,326 | $63M | $46.55 | $27M | +478,939 | +54.9% | |
| 40 | ORKA | 0.64% | 2,058,148 | $62M | $30.31 | $25M | +112,499 | +5.8% | |
| 41 | RCKT | 0.64% | 17,687,772 | $62M | $3.51 | $4M | — | — | |
| 42 | CMPS | 0.62% | 8,757,390 | $60M | $6.90 | $11M | +50,000 | +0.6% | |
| 43 | ISRG | 0.59% | 101,228 | $57M | $566.36 | -$33M | -101,228 | -50.0% | |
| 44 | RAPT | 0.57% | 1,637,165 | $55M | $33.87 | $18M | +166,666 | +11.3% | |
| 45 | CELC | 0.56% | 550,160 | $55M | $99.74 | — | +550,160 | — | NEW |
| 46 | VSTM | 0.52% | 6,576,306 | $51M | $7.72 | $3M | +1,150,000 | +21.2% | |
| 47 | ALKS | 0.48% | 1,672,356 | $47M | $27.98 | -$3M | — | — | |
| 48 | CNTA | 0.46% | 1,790,837 | $45M | $25.01 | -$11M | -500,910 | -21.9% | |
| 49 | KOD | 0.43% | 1,487,933 | $42M | $27.96 | — | +1,487,933 | — | NEW |
| 50 | AQST | 0.41% | 6,250,000 | $40M | $6.46 | $5M | — | — | |
| 51 | ARWR | 0.40% | 584,716 | $39M | $66.39 | — | +584,716 | — | NEW |
| 52 | SVRA | 0.37% | 5,952,380 | $36M | $6.03 | — | +5,952,380 | — | NEW |
| 53 | OBIO | 0.35% | 8,306,063 | $34M | $4.15 | $14M | — | — | |
| 54 | NGNE | 0.29% | 1,362,456 | $28M | $20.60 | $4M | — | — | |
| 55 | JBIO | 0.23% | 1,449,273 | $22M | $15.43 | $10M | — | — | |
| 56 | EVMN | 0.23% | 1,283,671 | $22M | $17.12 | — | +1,283,671 | — | NEW |
| 57 | KYMR | 0.19% | 240,000 | $19M | $77.81 | — | +240,000 | — | NEW |
| 58 | FLGT | 0.19% | 705,027 | $19M | $26.27 | — | +705,027 | — | NEW |
| 59 | CGEM | 0.18% | 1,705,960 | $18M | $10.35 | $8M | — | — | |
| 60 | HNGE | 0.17% | 353,500 | $16M | $46.45 | — | +353,500 | — | NEW |
| 61 | BEAM | 0.16% | 570,394 | $16M | $27.72 | — | +570,394 | — | NEW |
| 62 | HTFL | 0.15% | 495,000 | $14M | $29.15 | -$2M | — | — | |
| 63 | CMPX | 0.14% | 2,500,000 | $13M | $5.37 | $5M | — | — | |
| 64 | TNGX | 0.14% | 1,491,228 | $13M | $8.86 | — | +1,491,228 | — | NEW |
| 65 | LMRI | 0.12% | 650,000 | $12M | $18.50 | — | +650,000 | — | NEW |
| 66 | LRMR | 0.12% | 3,125,000 | $12M | $3.81 | $2M | — | — | |
| 67 | TEM | 0.12% | 200,000 | $12M | $59.05 | -$4M | — | — | |
| 68 | KLRS | 0.11% | 1,300,000 | $11M | $8.44 | — | +1,300,000 | — | NEW |
| 69 | IQV | 0.11% | 46,000 | $10M | $225.41 | — | +46,000 | — | NEW |
| 70 | PCSC | 0.10% | 742,500 | $10M | $13.03 | $2M | — | — | |
| 71 | CAPR | 0.07% | 250,000 | $7M | $28.86 | — | +250,000 | — | NEW |
| 72 | GPCR | 0.07% | 100,000 | $7M | $69.55 | — | +100,000 | — | NEW |
| 73 | IVA | 0.06% | 1,298,701 | $6M | $4.65 | — | +1,298,701 | — | NEW |
| 74 | MIST | 0.05% | 2,506,102 | $5M | $2.02 | $50K | — | — | |
| 75 | XGN | 0.05% | 790,462 | $5M | $6.08 | -$14M | -906,404 | -53.4% | |
| 76 | TENX | 0.05% | 378,346 | $5M | $12.19 | $2M | — | — | |
| 77 | CBIO | 0.05% | 372,856 | $4M | $11.86 | — | +372,856 | — | NEW |
| 78 | FDMT | 0.04% | 475,737 | $4M | $7.50 | — | +475,737 | — | NEW |
| 79 | CRVS | 0.04% | 447,607 | $3M | $7.70 | -$16M | -2,231,872 | -83.3% | |
| 80 | OMDA | 0.03% | 200,000 | $3M | $15.78 | -$1M | — | — | |
| 81 | MDLN | 0.03% | 70,000 | $3M | $42.00 | — | +70,000 | — | NEW |
| 82 | IRON | 0.02% | 30,000 | $2M | $79.41 | — | +30,000 | — | NEW |
| 83 | IMA | 0.02% | 334,445 | $2M | $6.90 | -$418K | — | — | |
| 84 | ERAS | 0.01% | 146,651 | $546K | $3.72 | — | +146,651 | — | NEW |
| 85 | ALEC | —% | — | — | — | -$21M | -6,990,806 | -100.0% | SOLD |
| 86 | CTMX | —% | — | — | — | -$11M | -3,461,500 | -100.0% | SOLD |
| 87 | DYN | —% | — | — | — | -$37M | -2,890,567 | -100.0% | SOLD |
| 88 | RNAM | —% | — | — | — | -$496M | -11,372,829 | -100.0% | SOLD |
| 89 | LENZ | —% | — | — | — | -$40M | -863,389 | -100.0% | SOLD |
| 90 | AKRO | —% | — | — | — | -$260M | -5,477,561 | -100.0% | SOLD |
| 91 | PEPG | —% | — | — | — | -$7M | -1,500,000 | -100.0% | SOLD |
| 92 | GEHC | —% | — | — | — | -$30M | -393,500 | -100.0% | SOLD |
| 93 | MRUS | —% | — | — | — | -$191M | -2,025,277 | -100.0% | SOLD |
| 94 | ADGM | —% | — | — | — | -$406K | -209,361 | -100.0% | SOLD |
| 95 | ABVX | —% | — | — | — | -$30M | -350,000 | -100.0% | SOLD |
| 96 | DGX | —% | — | — | — | -$48M | -250,000 | -100.0% | SOLD |