Asset Manager
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RTW INVESTMENTS, LP
Market Value
$9.8B
+0.3%
Holdings
91
-5
New Purchases
7
Added To
29
Closed
10
Reduced
12
Top 10 Concentration
51.4%
Turnover
18.7%
Top Buys (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| CGON | 4.84% | 0.86% | +3.98% | $473M |
| CELC | 3.55% | 0.56% | +2.99% | $347M |
| TNGX | 2.85% | 0.14% | +2.71% | $278M |
| ERAS | 2.67% | 0.01% | +2.67% | $261M |
| PTGX | 5.46% | 4.53% | +0.92% | $533M |
| SYRE | 2.15% | 1.40% | +0.75% | $210M |
| HNGE | 0.76% | 0.17% | +0.59% | $74M |
| ISRG | 1.04% | 0.59% | +0.45% | $101M |
| WAY | 0.40% | 0.00% | +0.40% | $39M |
| ORKA | 1.03% | 0.64% | +0.39% | $101M |
| CNTA | 0.83% | 0.46% | +0.38% | $82M |
| CADL | 0.32% | 0.00% | +0.32% | $31M |
| AKTS | 0.29% | 0.00% | +0.29% | $28M |
| DNTH | 0.21% | 0.00% | +0.21% | $21M |
| IPSC | 0.20% | 0.00% | +0.20% | $20M |
Top Sells (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| PEN | 0.00% | 2.76% | -2.76% | $0 |
| AXSM | 0.00% | 1.66% | -1.66% | $0 |
| MDGL | 10.68% | 11.91% | -1.23% | $1.0B |
| NTRA | 2.56% | 3.52% | -0.97% | $250M |
| PODD | 0.00% | 0.95% | -0.95% | $0 |
| MASI | 0.00% | 0.91% | -0.91% | $0 |
| PTCT | 5.40% | 6.04% | -0.64% | $528M |
| COGT | 2.15% | 2.77% | -0.62% | $210M |
| BBNX | 0.21% | 0.78% | -0.58% | $20M |
| RAPT | 0.00% | 0.57% | -0.57% | $0 |
| SYK | 0.34% | 0.88% | -0.55% | $33M |
| INSM | 8.10% | 8.65% | -0.54% | $792M |
| ARGX | 5.30% | 5.81% | -0.51% | $518M |
| QURE | 0.43% | 0.91% | -0.48% | $42M |
| APLS | 1.52% | 1.98% | -0.46% | $148M |
Sector Allocation Over Time
Market Cap Concentration
| Tier | Holdings | Value | Weight |
|---|---|---|---|
| Large Cap | 14 | $3.1B | 31.2% |
| Mid Cap | 35 | $5.2B | 52.9% |
| Small Cap | 33 | $1.4B | 14.8% |
| Micro Cap | 9 | $109M | 1.1% |
Portfolio Analytics
Avg Market Cap
$7.9B
Median Market Cap
$2.3B
Avg P/E
49.0
Median P/E
37.6
Avg Dividend Yield
0.00%
Avg Beta
0.99
# Stocks
91
# ETFs / Funds
0
Top Holdings (91 total)
| # | Symbol | % Port | Shares | Value | Avg Price | Q/Q Value Chg | Share Chg | Chg % | Status |
|---|---|---|---|---|---|---|---|---|---|
| 1 | MDGL | 10.68% | 1,993,687 | $1.0B | $523.47 | -$117M | — | — | |
| 2 | INSM | 8.10% | 4,842,880 | $792M | $163.52 | -$51M | +1 | — | |
| 3 | PTGX | 5.46% | 5,059,053 | $533M | $105.40 | $91M | — | — | |
| 4 | PTCT | 5.40% | 7,746,415 | $528M | $68.13 | -$61M | — | — | |
| 5 | ARGX | 5.30% | 709,446 | $518M | $730.25 | -$48M | +35,949 | +5.3% | |
| 6 | CGON | 4.84% | 6,984,808 | $473M | $67.68 | $389M | +4,972,681 | +247.1% | |
| 7 | CELC | 3.55% | 3,039,621 | $347M | $114.14 | $292M | +2,489,461 | +452.5% | |
| 8 | TNGX | 2.85% | 13,300,620 | $278M | $20.92 | $265M | +11,809,392 | +791.9% | |
| 9 | ERAS | 2.67% | 16,157,175 | $261M | $16.18 | $261M | +16,010,524 | +10917.4% | |
| 10 | NTRA | 2.56% | 1,250,000 | $250M | $199.99 | -$94M | -250,000 | -16.7% | |
| 11 | RDNT | 2.45% | 4,285,000 | $239M | $55.89 | -$42M | +346,500 | +8.8% | |
| 12 | TARS | 2.40% | 3,346,025 | $235M | $70.15 | -$38M | +10,705 | +0.3% | |
| 13 | SYRE | 2.15% | 4,171,996 | $210M | $50.44 | $74M | — | — | |
| 14 | COGT | 2.15% | 5,458,675 | $210M | $38.49 | -$60M | -2,133,566 | -28.1% | |
| 15 | IRTC | 2.01% | 1,668,500 | $197M | $118.02 | -$13M | +486,510 | +41.2% | |
| 16 | STOK | 1.87% | 5,623,525 | $183M | $32.56 | $7M | +76,669 | +1.4% | |
| 17 | CYTK | 1.83% | 2,721,158 | $179M | $65.91 | $6M | — | — | |
| 18 | ACAD | 1.63% | 7,144,524 | $159M | $22.26 | -$32M | — | — | |
| 19 | ESTA | 1.54% | 2,655,695 | $151M | $56.78 | -$38M | +66,864 | +2.6% | |
| 20 | APLS | 1.52% | 3,685,045 | $148M | $40.23 | -$44M | -3,981,719 | -51.9% | |
| 21 | IMCR | 1.50% | 4,869,798 | $147M | $30.15 | -$22M | — | — | |
| 22 | RGEN | 1.45% | 1,206,000 | $142M | $117.82 | -$32M | +142,000 | +13.3% | |
| 23 | NBIX | 1.43% | 1,062,072 | $140M | $131.74 | -$11M | — | — | |
| 24 | GH | 1.40% | 1,481,033 | $137M | $92.37 | -$14M | — | — | |
| 25 | IMTX | 1.30% | 12,869,340 | $127M | $9.84 | $7M | +1,435,986 | +12.6% | |
| 26 | ZLAB | 1.27% | 6,574,032 | $124M | $18.81 | $900K | -385,000 | -5.5% | |
| 27 | BLTE | 1.17% | 715,332 | $114M | $159.44 | -$372K | — | — | |
| 28 | ISRG | 1.04% | 220,000 | $101M | $460.99 | $44M | +118,772 | +117.3% | |
| 29 | ORKA | 1.03% | 2,058,148 | $101M | $49.05 | $39M | — | — | |
| 30 | GHRS | 0.85% | 5,933,815 | $83M | $14.06 | $8M | — | — | |
| 31 | XNCR | 0.84% | 6,777,461 | $82M | $12.06 | -$22M | — | — | |
| 32 | URGN | 0.84% | 4,543,895 | $82M | $17.98 | -$25M | — | — | |
| 33 | CNTA | 0.83% | 2,054,175 | $82M | $39.72 | $37M | +263,338 | +14.7% | |
| 34 | IMVT | 0.81% | 3,177,849 | $79M | $24.84 | -$2M | -1 | — | |
| 35 | RARE | 0.78% | 3,648,795 | $76M | $20.95 | $7M | +648,656 | +21.6% | |
| 36 | HNGE | 0.76% | 1,930,000 | $74M | $38.56 | $58M | +1,576,500 | +446.0% | |
| 37 | CSTL | 0.69% | 2,758,335 | $68M | $24.55 | -$15M | +643,098 | +30.4% | |
| 38 | RCKT | 0.65% | 17,687,772 | $63M | $3.58 | $1M | — | — | |
| 39 | TSHA | 0.63% | 13,680,248 | $61M | $4.47 | -$29M | -2,718,049 | -16.6% | |
| 40 | ALKS | 0.60% | 1,672,356 | $59M | $35.36 | $12M | — | — | |
| 41 | CMPS | 0.60% | 10,632,390 | $59M | $5.53 | -$2M | +1,875,000 | +21.4% | |
| 42 | KOD | 0.58% | 1,487,934 | $57M | $38.12 | $15M | +1 | — | |
| 43 | REPL | 0.58% | 7,356,916 | $56M | $7.65 | -$13M | +216,564 | +3.0% | |
| 44 | CRNX | 0.54% | 1,451,326 | $53M | $36.32 | -$10M | +100,000 | +7.4% | |
| 45 | QURE | 0.43% | 2,586,356 | $42M | $16.35 | -$47M | -1,125,106 | -30.3% | |
| 46 | WAY | 0.40% | 1,630,000 | $39M | $24.11 | — | +1,630,000 | — | NEW |
| 47 | ARWR | 0.38% | 585,682 | $37M | $62.70 | -$2M | +966 | +0.2% | |
| 48 | OBIO | 0.36% | 8,306,063 | $35M | $4.25 | $831K | — | — | |
| 49 | 0LOV.L | 0.36% | 6,576,306 | $35M | $5.30 | -$16M | — | — | |
| 50 | EVMN | 0.35% | 1,502,235 | $35M | $22.99 | $13M | +218,564 | +17.0% | |
| 51 | SYK | 0.34% | 100,000 | $33M | $328.59 | -$53M | -145,000 | -59.2% | |
| 52 | SVRA | 0.33% | 5,952,380 | $32M | $5.46 | -$3M | — | — | |
| 53 | CADL | 0.32% | 6,422,018 | $31M | $4.90 | — | +6,422,018 | — | NEW |
| 54 | AQST | 0.32% | 7,426,471 | $31M | $4.15 | -$10M | +1,176,471 | +18.8% | |
| 55 | AKTS | 0.29% | 1,592,043 | $28M | $17.89 | — | +1,592,043 | — | NEW |
| 56 | NGNE | 0.28% | 1,362,456 | $27M | $20.16 | -$599K | — | — | |
| 57 | CGEM | 0.25% | 1,705,960 | $24M | $14.21 | $7M | — | — | |
| 58 | CMPX | 0.23% | 4,186,599 | $22M | $5.29 | $9M | +1,686,599 | +67.5% | |
| 59 | DNTH | 0.21% | 248,063 | $21M | $83.92 | — | +248,063 | — | NEW |
| 60 | FLGT | 0.21% | 1,289,000 | $20M | $15.90 | $2M | +583,973 | +82.8% | |
| 61 | BBNX | 0.21% | 2,000,000 | $20M | $10.02 | -$56M | -500,000 | -20.0% | |
| 62 | KYMR | 0.20% | 240,000 | $20M | $83.29 | $1M | — | — | |
| 63 | IPSC | 0.20% | 8,695,652 | $20M | $2.26 | — | +8,695,652 | — | NEW |
| 64 | BEAM | 0.14% | 570,394 | $14M | $23.83 | -$2M | — | — | |
| 65 | OCGN | 0.12% | 6,666,666 | $12M | $1.81 | — | +6,666,666 | — | NEW |
| 66 | HTFL | 0.12% | 495,000 | $12M | $24.33 | -$2M | — | — | |
| 67 | WVE | 0.10% | 1,350,000 | $10M | $7.25 | -$13M | — | — | |
| 68 | JBIO | 0.08% | 573,205 | $8M | $14.05 | -$14M | -876,068 | -60.5% | |
| 69 | CAPR | 0.08% | 250,000 | $8M | $30.40 | $385K | — | — | |
| 70 | MIST | 0.08% | 6,331,001 | $8M | $1.19 | $2M | +3,824,899 | +152.6% | |
| 71 | KLRS | 0.08% | 1,300,000 | $8M | $5.77 | -$3M | — | — | |
| 72 | IVA | 0.07% | 1,298,702 | $7M | $5.55 | $1M | +1 | — | |
| 73 | LRMR | 0.07% | 1,500,000 | $7M | $4.50 | -$5M | -1,625,000 | -52.0% | |
| 74 | DFTX | 0.06% | 300,000 | $6M | $18.90 | — | +300,000 | — | NEW |
| 75 | LMRI | 0.06% | 650,000 | $6M | $8.60 | -$6M | — | — | |
| 76 | FDMT | 0.05% | 475,737 | $4M | $9.31 | $861K | — | — | |
| 77 | MDLN | 0.03% | 70,000 | $3M | $44.50 | $175K | — | — | |
| 78 | OMDA | 0.03% | 200,000 | $3M | $12.57 | -$642K | — | — | |
| 79 | IRON | 0.02% | 30,000 | $2M | $63.94 | -$464K | — | — | |
| 80 | IMA | 0.02% | 334,445 | $2M | $5.00 | -$635K | — | — | |
| 81 | XGN | 0.01% | 395,231 | $1M | $3.00 | -$4M | -395,231 | -50.0% | |
| 82 | PEN | —% | — | — | — | -$269M | -866,499 | -100.0% | SOLD |
| 83 | IQV | —% | — | — | — | -$10M | -46,000 | -100.0% | SOLD |
| 84 | MASI | —% | — | — | — | -$89M | -683,294 | -100.0% | SOLD |
| 85 | GPCR | —% | — | — | — | -$7M | -100,000 | -100.0% | SOLD |
| 86 | AXSM | —% | — | — | — | -$162M | -888,001 | -100.0% | SOLD |
| 87 | RAPT | —% | — | — | — | -$55M | -1,637,165 | -100.0% | SOLD |
| 88 | ATAI | —% | — | — | — | -$8M | -2,000,000 | -100.0% | SOLD |
| 89 | TEM | —% | — | — | — | -$12M | -200,000 | -100.0% | SOLD |
| 90 | PODD | —% | — | — | — | -$92M | -324,600 | -100.0% | SOLD |
| 91 | CRVS | —% | — | — | — | -$3M | -447,607 | -100.0% | SOLD |