Asset Manager
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RTW INVESTMENTS, LP
Market Value
$7.8B
+12.8%
Holdings
77
+5
New Purchases
10
Added To
17
Closed
8
Reduced
11
Top 10 Concentration
54.5%
Turnover
23.4%
Top Buys (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| MDGL | 11.79% | 8.78% | +3.01% | $914M |
| RNAM | 6.39% | 3.97% | +2.42% | $496M |
| INSM | 5.73% | 4.52% | +1.21% | $444M |
| ARGX | 6.41% | 5.40% | +1.01% | $497M |
| STOK | 1.55% | 0.85% | +0.71% | $120M |
| XNCR | 0.94% | 0.27% | +0.67% | $73M |
| COGT | 0.64% | 0.00% | +0.64% | $50M |
| PTCT | 6.13% | 5.50% | +0.63% | $475M |
| CYTK | 1.93% | 1.31% | +0.62% | $150M |
| TARS | 2.43% | 1.83% | +0.60% | $189M |
| GH | 1.19% | 0.65% | +0.54% | $93M |
| RDNT | 2.77% | 2.23% | +0.54% | $215M |
| AQST | 0.45% | 0.00% | +0.45% | $35M |
| CNTA | 0.72% | 0.29% | +0.42% | $56M |
| IMTX | 0.97% | 0.55% | +0.42% | $75M |
Top Sells (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| VRNA | 0.00% | 4.20% | -4.20% | $0 |
| NTRA | 4.15% | 6.37% | -2.22% | $322M |
| ZLAB | 1.00% | 2.82% | -1.82% | $78M |
| ALKS | 0.65% | 1.95% | -1.30% | $50M |
| SYK | 2.34% | 3.40% | -1.06% | $181M |
| AKRO | 3.35% | 4.25% | -0.90% | $260M |
| ABT | 0.00% | 0.88% | -0.88% | $0 |
| ACAD | 1.97% | 2.82% | -0.86% | $152M |
| DGX | 0.61% | 1.31% | -0.69% | $48M |
| MRUS | 2.46% | 3.06% | -0.60% | $191M |
| AXSM | 1.75% | 2.30% | -0.55% | $136M |
| SLNO | 0.00% | 0.52% | -0.52% | $0 |
| MLTX | 0.00% | 0.51% | -0.51% | $0 |
| ISRG | 1.17% | 1.60% | -0.43% | $91M |
| PEN | 2.83% | 3.22% | -0.39% | $220M |
Sector Allocation Over Time
Market Cap Concentration
| Tier | Holdings | Value | Weight |
|---|---|---|---|
| Large Cap | 15 | $3.5B | 45.1% |
| Mid Cap | 25 | $2.9B | 37.4% |
| Small Cap | 25 | $1.2B | 15.3% |
| Micro Cap | 12 | $172M | 2.2% |
Portfolio Analytics
Avg Market Cap
$12.3B
Median Market Cap
$2.7B
Avg P/E
68.4
Median P/E
32.3
Avg Dividend Yield
0.00%
Avg Beta
0.87
# Stocks
77
# ETFs / Funds
0
Top Holdings (77 total)
| # | Symbol | % Port | Shares | Value | Avg Price | Q/Q Value Chg | Share Chg | Chg % | Status |
|---|---|---|---|---|---|---|---|---|---|
| 1 | MDGL | 11.79% | 1,993,687 | $914M | $458.66 | $311M | — | — | |
| 2 | ARGX | 6.41% | 673,497 | $497M | $737.56 | $125M | — | — | |
| 3 | RNAM | 6.39% | 11,372,829 | $496M | $43.57 | $222M | +1,753,984 | +18.2% | |
| 4 | PTCT | 6.13% | 7,746,415 | $475M | $61.37 | $97M | — | — | |
| 5 | INSM | 5.73% | 3,084,558 | $444M | $144.01 | $134M | — | — | |
| 6 | PTGX | 4.93% | 5,756,277 | $382M | $66.43 | $64M | — | — | |
| 7 | NTRA | 4.15% | 2,000,000 | $322M | $160.97 | -$116M | -593,645 | -22.9% | |
| 8 | AKRO | 3.35% | 5,477,561 | $260M | $47.48 | -$32M | — | — | |
| 9 | PEN | 2.83% | 866,499 | $220M | $253.32 | -$2M | +2,946 | +0.3% | |
| 10 | RDNT | 2.77% | 2,815,544 | $215M | $76.21 | $61M | +125,200 | +4.7% | |
| 11 | MRUS | 2.46% | 2,025,277 | $191M | $94.15 | -$20M | -1,975,276 | -49.4% | |
| 12 | TARS | 2.43% | 3,177,436 | $189M | $59.43 | $63M | +65,756 | +2.1% | |
| 13 | SYK | 2.34% | 490,000 | $181M | $369.67 | -$52M | -100,517 | -17.0% | |
| 14 | IMCR | 2.28% | 4,869,798 | $177M | $36.33 | $24M | — | — | |
| 15 | ACAD | 1.97% | 7,144,524 | $152M | $21.34 | -$42M | -1,851,023 | -20.6% | |
| 16 | CYTK | 1.93% | 2,721,158 | $150M | $54.96 | $60M | — | — | |
| 17 | NBIX | 1.92% | 1,062,072 | $149M | $140.38 | $16M | — | — | |
| 18 | AXSM | 1.75% | 1,118,883 | $136M | $121.45 | -$22M | -398,020 | -26.2% | |
| 19 | STOK | 1.55% | 5,123,525 | $120M | $23.50 | $62M | — | — | |
| 20 | APGE | 1.39% | 2,712,097 | $108M | $39.73 | -$10M | — | — | |
| 21 | ESTA | 1.37% | 2,588,831 | $106M | $40.99 | -$4M | +4,700 | +0.2% | |
| 22 | MASI | 1.30% | 683,294 | $101M | $147.55 | -$14M | — | — | |
| 23 | RARE | 1.26% | 3,258,266 | $98M | $30.08 | $36M | +1,550,864 | +90.8% | |
| 24 | GH | 1.19% | 1,481,033 | $93M | $62.48 | $48M | +624,532 | +72.9% | |
| 25 | ISRG | 1.17% | 202,456 | $91M | $447.23 | -$19M | — | — | |
| 26 | GHRS | 1.03% | 5,569,564 | $80M | $14.30 | $12M | +29,107 | +0.5% | |
| 27 | TSHA | 1.03% | 24,354,291 | $80M | $3.27 | $22M | -667,293 | -2.7% | |
| 28 | ZLAB | 1.00% | 2,291,372 | $78M | $33.89 | -$116M | -3,245,504 | -58.6% | |
| 29 | IMTX | 0.97% | 8,815,617 | $75M | $8.52 | $38M | +1,845,465 | +26.5% | |
| 30 | XNCR | 0.94% | 6,221,054 | $73M | $11.73 | $54M | +3,818,171 | +158.9% | |
| 31 | CGON | 0.88% | 1,701,216 | $69M | $40.28 | $24M | — | — | |
| 32 | BBNX | 0.85% | 3,299,191 | $66M | $19.87 | $18M | — | — | |
| 33 | SYRE | 0.78% | 3,621,996 | $61M | $16.76 | $6M | — | — | |
| 34 | RCKT | 0.74% | 17,687,772 | $58M | $3.26 | $14M | — | — | |
| 35 | CNTA | 0.72% | 2,291,747 | $56M | $24.25 | $35M | +761,911 | +49.8% | |
| 36 | ALKS | 0.65% | 1,672,356 | $50M | $30.00 | -$84M | -3,009,933 | -64.3% | |
| 37 | CMPS | 0.64% | 8,707,390 | $50M | $5.73 | $27M | +485,461 | +5.9% | |
| 38 | COGT | 0.64% | 3,467,486 | $50M | $14.36 | — | +3,467,486 | — | NEW |
| 39 | VSTM | 0.62% | 5,426,306 | $48M | $8.83 | $30M | +1,174,690 | +27.6% | |
| 40 | DGX | 0.61% | 250,000 | $48M | $190.58 | -$42M | -250,000 | -50.0% | |
| 41 | LENZ | 0.52% | 863,389 | $40M | $46.58 | $15M | — | — | |
| 42 | RAPT | 0.49% | 1,470,499 | $38M | $25.79 | $26M | — | — | |
| 43 | ORKA | 0.48% | 1,945,649 | $37M | $19.23 | $16M | — | — | |
| 44 | DYN | 0.47% | 2,890,567 | $37M | $12.65 | $20M | +1,200,000 | +71.0% | |
| 45 | CRNX | 0.47% | 872,387 | $36M | $41.65 | $23M | +405,387 | +86.8% | |
| 46 | AQST | 0.45% | 6,250,000 | $35M | $5.59 | — | +6,250,000 | — | NEW |
| 47 | ABVX | 0.38% | 350,000 | $30M | $84.90 | — | +350,000 | — | NEW |
| 48 | GEHC | 0.38% | 393,500 | $30M | $75.10 | -$17M | -232,500 | -37.1% | |
| 49 | REPL | 0.35% | 6,395,732 | $27M | $4.19 | $8M | +4,330,722 | +209.7% | |
| 50 | NGNE | 0.30% | 1,362,456 | $24M | $17.33 | $3M | — | — | |
| 51 | BLTE | 0.30% | 312,500 | $23M | $74.00 | — | +312,500 | — | NEW |
| 52 | ALEC | 0.27% | 6,990,806 | $21M | $2.96 | — | +6,990,806 | — | NEW |
| 53 | OBIO | 0.27% | 8,306,063 | $21M | $2.48 | -$2M | +1 | — | |
| 54 | CRVS | 0.25% | 2,679,479 | $20M | $7.37 | $9M | — | — | |
| 55 | XGN | 0.24% | 1,696,866 | $19M | $10.99 | $7M | — | — | |
| 56 | HTFL | 0.21% | 495,000 | $17M | $33.66 | — | +495,000 | — | NEW |
| 57 | TEM | 0.21% | 200,000 | $16M | $80.71 | -$9M | -200,000 | -50.0% | |
| 58 | JBIO | 0.16% | 1,449,273 | $13M | $8.63 | -$2M | — | — | |
| 59 | CTMX | 0.14% | 3,461,500 | $11M | $3.19 | $3M | — | — | |
| 60 | CGEM | 0.13% | 1,705,960 | $10M | $5.93 | -$3M | — | — | |
| 61 | LRMR | 0.13% | 3,125,000 | $10M | $3.23 | — | +3,125,000 | — | NEW |
| 62 | CMPX | 0.11% | 2,500,000 | $9M | $3.50 | — | +2,500,000 | — | NEW |
| 63 | PCSC | 0.10% | 742,500 | $8M | $10.56 | -$45K | — | — | |
| 64 | PEPG | 0.09% | 1,500,000 | $7M | $4.62 | — | +1,500,000 | — | NEW |
| 65 | MIST | 0.06% | 2,506,102 | $5M | $2.00 | $150K | — | — | |
| 66 | OMDA | 0.06% | 200,000 | $4M | $22.11 | $762K | — | — | |
| 67 | TENX | 0.04% | 378,346 | $3M | $7.61 | $700K | — | — | |
| 68 | IMA | 0.04% | 334,445 | $3M | $8.15 | — | +334,445 | — | NEW |
| 69 | ADGM | 0.01% | 209,361 | $406K | $1.94 | $134K | — | — | |
| 70 | ABT | —% | — | — | — | -$60M | -444,000 | -100.0% | SOLD |
| 71 | MLTX | —% | — | — | — | -$35M | -741,090 | -100.0% | SOLD |
| 72 | CBLL | —% | — | — | — | -$3M | -150,000 | -100.0% | SOLD |
| 73 | KMTS | —% | — | — | — | -$3M | -200,000 | -100.0% | SOLD |
| 74 | ETNB | —% | — | — | — | -$19M | -1,967,527 | -100.0% | SOLD |
| 75 | VRNA | —% | — | — | — | -$289M | -3,051,878 | -100.0% | SOLD |
| 76 | CRGX | —% | — | — | — | -$5M | -1,212,562 | -100.0% | SOLD |
| 77 | SLNO | —% | — | — | — | -$36M | -424,408 | -100.0% | SOLD |