Asset Manager
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Sofinnova Investments, Inc.
Market Value
$1.5B
+8.8%
Holdings
59
-5
New Purchases
9
Added To
15
Closed
8
Reduced
22
Top 10 Concentration
57.9%
Turnover
28.8%
Top Buys (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| VRTX | 3.00% | 0.00% | +3.00% | $46M |
| UTHR | 5.19% | 2.41% | +2.79% | $80M |
| AXSM | 3.10% | 0.69% | +2.41% | $48M |
| RAPP | 3.76% | 1.60% | +2.15% | $58M |
| GKOS | 1.66% | 0.00% | +1.66% | $26M |
| RNAM | 2.48% | 1.17% | +1.31% | $38M |
| APGE | 1.46% | 0.23% | +1.23% | $22M |
| CELC | 0.81% | 0.00% | +0.81% | $13M |
| GILD | 9.03% | 8.23% | +0.80% | $139M |
| COGT | 1.99% | 1.20% | +0.79% | $31M |
| GEHC | 0.74% | 0.00% | +0.74% | $11M |
| ROIV | 3.10% | 2.46% | +0.64% | $48M |
| VERA | 5.27% | 4.65% | +0.62% | $81M |
| PRAX | 0.60% | 0.05% | +0.55% | $9M |
| EXAS | 1.30% | 0.78% | +0.52% | $20M |
Top Sells (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| LLY | 0.00% | 5.34% | -5.34% | $0 |
| NTRA | 16.21% | 18.51% | -2.29% | $250M |
| SLNO | 0.73% | 2.46% | -1.73% | $11M |
| IDYA | 1.63% | 3.19% | -1.56% | $25M |
| INSM | 0.98% | 2.23% | -1.26% | $15M |
| ABBV | 2.27% | 3.49% | -1.22% | $35M |
| INZY | 0.00% | 1.21% | -1.21% | $0 |
| REPL | 0.00% | 1.19% | -1.19% | $0 |
| ANAB | 0.51% | 1.62% | -1.11% | $8M |
| SNDX | 0.00% | 1.01% | -1.01% | $0 |
| RYTM | 1.62% | 2.62% | -1.00% | $25M |
| YMAB | 0.00% | 0.70% | -0.70% | $0 |
| SUPN | 1.17% | 1.78% | -0.61% | $18M |
| AKRO | 1.46% | 2.07% | -0.61% | $22M |
| AVBP | 2.03% | 2.61% | -0.58% | $31M |
Sector Allocation Over Time
Market Cap Concentration
| Tier | Holdings | Value | Weight |
|---|---|---|---|
| Mega Cap | 2 | $35M | 2.3% |
| Large Cap | 14 | $925M | 60.1% |
| Mid Cap | 22 | $404M | 26.2% |
| Small Cap | 15 | $153M | 9.9% |
| Micro Cap | 6 | $23M | 1.5% |
Portfolio Analytics
Avg Market Cap
$41.3B
Median Market Cap
$3.6B
Avg P/E
27.6
Median P/E
22.8
Avg Dividend Yield
0.00%
Avg Beta
0.87
# Stocks
59
# ETFs / Funds
0
Top Holdings (59 total)
| # | Symbol | % Port | Shares | Value | Avg Price | Q/Q Value Chg | Share Chg | Chg % | Status |
|---|---|---|---|---|---|---|---|---|---|
| 1 | NTRA | 16.21% | 1,550,280 | $250M | $160.97 | -$12M | — | — | |
| 2 | GILD | 9.03% | 1,252,312 | $139M | $111.00 | $23M | +202,004 | +19.2% | |
| 3 | VERA | 5.27% | 2,793,987 | $81M | $29.06 | $15M | — | — | |
| 4 | UTHR | 5.19% | 190,626 | $80M | $419.21 | $46M | +72,113 | +60.9% | |
| 5 | JAZZ | 5.04% | 588,828 | $78M | $131.80 | $4M | -105,268 | -15.2% | |
| 6 | RAPP | 3.76% | 1,947,579 | $58M | $29.70 | $35M | -48,015 | -2.4% | |
| 7 | BSX | 3.61% | 569,427 | $56M | $97.63 | $9M | +138,227 | +32.1% | |
| 8 | DXCM | 3.41% | 779,616 | $52M | $67.29 | $7M | +255,922 | +48.9% | |
| 9 | ISRG | 3.22% | 110,896 | $50M | $447.23 | $11M | +40,254 | +57.0% | |
| 10 | AXSM | 3.10% | 393,499 | $48M | $121.45 | $38M | +299,889 | +320.4% | |
| 11 | ROIV | 3.10% | 3,149,270 | $48M | $15.13 | $13M | +60,456 | +2.0% | |
| 12 | VRTX | 3.00% | 117,875 | $46M | $391.64 | — | +117,875 | — | NEW |
| 13 | BBIO | 2.81% | 831,847 | $43M | $51.94 | $324K | -161,246 | -16.2% | |
| 14 | RNAM | 2.48% | 875,925 | $38M | $43.57 | $22M | +291,124 | +49.8% | |
| 15 | ABBV | 2.27% | 150,966 | $35M | $231.54 | -$14M | -114,884 | -43.2% | |
| 16 | AVBP | 2.03% | 1,696,752 | $31M | $18.45 | -$6M | — | — | |
| 17 | COGT | 1.99% | 2,127,941 | $31M | $14.36 | $14M | -227,564 | -9.7% | |
| 18 | GKOS | 1.66% | 312,994 | $26M | $81.55 | — | +312,994 | — | NEW |
| 19 | IDYA | 1.63% | 922,695 | $25M | $27.21 | -$20M | -1,225,100 | -57.0% | |
| 20 | RYTM | 1.62% | 246,966 | $25M | $100.99 | -$12M | -339,044 | -57.9% | |
| 21 | AKRO | 1.46% | 473,625 | $22M | $47.48 | -$7M | -75,163 | -13.7% | |
| 22 | APGE | 1.46% | 565,417 | $22M | $39.73 | $19M | +489,237 | +642.2% | |
| 23 | EXAS | 1.30% | 365,000 | $20M | $54.71 | $9M | +156,700 | +75.2% | |
| 24 | IMTX | 1.23% | 2,227,837 | $19M | $8.52 | $7M | -12,691 | -0.6% | |
| 25 | SUPN | 1.17% | 377,066 | $18M | $47.79 | -$7M | -422,187 | -52.8% | |
| 26 | RCUS | 1.08% | 1,222,263 | $17M | $13.60 | $7M | +6,247 | +0.5% | |
| 27 | MRUS | 1.02% | 166,729 | $16M | $94.15 | -$6M | -237,833 | -58.8% | |
| 28 | INSM | 0.98% | 104,339 | $15M | $144.01 | -$17M | -209,584 | -66.8% | |
| 29 | INBX | 0.96% | 440,092 | $15M | $33.68 | $5M | -268,586 | -37.9% | |
| 30 | BIOA | 0.88% | 2,293,788 | $13M | $5.88 | $4M | -11,113 | -0.5% | |
| 31 | CELC | 0.81% | 253,375 | $13M | $49.40 | — | +253,375 | — | NEW |
| 32 | DYN | 0.81% | 985,828 | $12M | $12.65 | $7M | +370,963 | +60.3% | |
| 33 | PTCT | 0.75% | 186,932 | $11M | $61.37 | -$7M | -189,007 | -50.3% | |
| 34 | GEHC | 0.74% | 151,085 | $11M | $75.10 | — | +151,085 | — | NEW |
| 35 | SLNO | 0.73% | 166,281 | $11M | $67.60 | -$24M | -248,938 | -60.0% | |
| 36 | PRAX | 0.60% | 172,833 | $9M | $53.00 | $8M | +157,116 | +999.7% | |
| 37 | SVRA | 0.56% | 2,427,724 | $9M | $3.57 | $3M | -29,628 | -1.2% | |
| 38 | EWTX | 0.55% | 520,240 | $8M | $16.22 | -$960K | -196,633 | -27.4% | |
| 39 | ANAB | 0.51% | 254,268 | $8M | $30.62 | -$15M | -778,094 | -75.4% | |
| 40 | CMPX | 0.46% | 2,028,886 | $7M | $3.50 | — | +2,028,886 | — | NEW |
| 41 | NKTR | 0.44% | 118,419 | $7M | $56.90 | — | +118,419 | — | NEW |
| 42 | CDTX | 0.34% | 54,197 | $5M | $95.76 | -$7M | -196,834 | -78.4% | |
| 43 | IMNM | 0.33% | 436,051 | $5M | $11.71 | -$2M | -342,425 | -44.0% | |
| 44 | NXTC | 0.08% | 222,654 | $1M | $5.86 | — | +222,654 | — | NEW |
| 45 | SRRK | 0.08% | 31,410 | $1M | $37.24 | $233K | +4,970 | +18.8% | |
| 46 | JBIO | 0.06% | 107,391 | $927K | $8.63 | -$146K | — | — | |
| 47 | IRON | 0.06% | 13,553 | $896K | $66.08 | $508K | +6,241 | +85.3% | |
| 48 | BOLT | 0.05% | 137,721 | $733K | $5.32 | -$62K | — | — | |
| 49 | ACAD | 0.04% | 26,800 | $572K | $21.34 | — | +26,800 | — | NEW |
| 50 | ESTA | 0.03% | 10,787 | $442K | $40.99 | -$759K | -17,333 | -61.6% | |
| 51 | IMA | 0.02% | 31,884 | $260K | $8.15 | — | +31,884 | — | NEW |
| 52 | GPCR | —% | — | — | — | -$712K | -34,353 | -100.0% | SOLD |
| 53 | IKNA | —% | — | — | — | -$513K | -382,616 | -100.0% | SOLD |
| 54 | REPL | —% | — | — | — | -$17M | -1,806,529 | -100.0% | SOLD |
| 55 | SNDX | —% | — | — | — | -$14M | -1,524,440 | -100.0% | SOLD |
| 56 | MTSR | —% | — | — | — | -$1M | -36,191 | -100.0% | SOLD |
| 57 | INZY | —% | — | — | — | -$17M | -4,280,308 | -100.0% | SOLD |
| 58 | YMAB | —% | — | — | — | -$10M | -2,194,278 | -100.0% | SOLD |
| 59 | LLY | —% | — | — | — | -$76M | -97,018 | -100.0% | SOLD |
Options Breakdown
4 Calls
$19M Call Value
7 Puts
$133M Put Value
7.17 P/C Ratio