Asset Manager
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Sofinnova Investments, Inc.
Market Value
$2.0B
-7.9%
Holdings
73
+11
New Purchases
17
Added To
22
Closed
14
Reduced
11
Top 10 Concentration
56.0%
Turnover
42.5%
Top Buys (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| AZN | 4.56% | 0.00% | +4.56% | $90M |
| RARE | 3.34% | 0.09% | +3.25% | $66M |
| BMY | 6.12% | 3.81% | +2.31% | $121M |
| BIIB | 2.13% | 0.00% | +2.13% | $42M |
| AXSM | 1.82% | 0.10% | +1.72% | $36M |
| INSM | 2.87% | 1.27% | +1.60% | $57M |
| ALC | 2.79% | 1.22% | +1.57% | $55M |
| UTHR | 4.81% | 3.59% | +1.23% | $95M |
| SUPN | 2.50% | 1.28% | +1.22% | $49M |
| GMAB | 1.02% | 0.00% | +1.02% | $20M |
| NKTR | 1.86% | 0.87% | +0.99% | $37M |
| COGT | 4.13% | 3.27% | +0.85% | $81M |
| XENE | 0.90% | 0.13% | +0.77% | $18M |
| SYK | 0.74% | 0.00% | +0.74% | $15M |
| CELC | 2.12% | 1.39% | +0.73% | $42M |
Top Sells (by % of Portfolio)
| Symbol | Cur % | Prior % | Chg % | Value |
|---|---|---|---|---|
| VRTX | 0.00% | 3.48% | -3.48% | $0 |
| ABBV | 0.00% | 3.39% | -3.39% | $0 |
| ISRG | 0.00% | 3.36% | -3.36% | $0 |
| LLY | 0.00% | 3.09% | -3.09% | $0 |
| RNAM | 0.00% | 2.51% | -2.51% | $0 |
| APGE | 0.00% | 1.89% | -1.89% | $0 |
| JAZZ | 5.74% | 7.62% | -1.88% | $113M |
| CDTX | 0.00% | 1.86% | -1.86% | $0 |
| GKOS | 0.00% | 1.52% | -1.52% | $0 |
| CNTA | 0.00% | 1.29% | -1.29% | $0 |
| BBIO | 1.54% | 2.57% | -1.03% | $30M |
| VERA | 5.70% | 6.61% | -0.91% | $112M |
| NTRA | 15.73% | 16.58% | -0.86% | $310M |
| PRAX | 1.04% | 1.73% | -0.69% | $21M |
| GEHC | 0.00% | 0.62% | -0.62% | $0 |
Sector Allocation Over Time
Market Cap Concentration
| Tier | Holdings | Value | Weight |
|---|---|---|---|
| Mega Cap | 3 | $90M | 4.6% |
| Large Cap | 18 | $940M | 47.7% |
| Mid Cap | 29 | $547M | 27.8% |
| Small Cap | 15 | $338M | 17.2% |
| Micro Cap | 8 | $56M | 2.9% |
Portfolio Analytics
Avg Market Cap
$38.3B
Median Market Cap
$3.8B
Avg P/E
39.1
Median P/E
27.7
Avg Dividend Yield
0.00%
Avg Beta
0.91
# Stocks
73
# ETFs / Funds
0
Top Holdings (73 total)
| # | Symbol | % Port | Shares | Value | Avg Price | Q/Q Value Chg | Share Chg | Chg % | Status |
|---|---|---|---|---|---|---|---|---|---|
| 1 | NTRA | 15.73% | 1,550,280 | $310M | $199.99 | -$45M | — | — | |
| 2 | BMY | 6.12% | 1,988,721 | $121M | $60.65 | $39M | +475,727 | +31.4% | |
| 3 | JAZZ | 5.74% | 598,327 | $113M | $189.05 | -$50M | -361,533 | -37.7% | |
| 4 | VERA | 5.70% | 2,793,987 | $112M | $40.23 | -$29M | — | — | |
| 5 | UTHR | 4.81% | 160,070 | $95M | $592.98 | $18M | +2,429 | +1.5% | |
| 6 | AZN | 4.56% | 456,031 | $90M | $197.22 | — | +456,031 | — | NEW |
| 7 | COGT | 4.13% | 2,113,551 | $81M | $38.49 | $11M | +139,926 | +7.1% | |
| 8 | RARE | 3.34% | 3,145,888 | $66M | $20.95 | $64M | +3,062,588 | +3676.6% | |
| 9 | RAPP | 3.02% | 1,904,408 | $60M | $31.29 | $2M | — | — | |
| 10 | INSM | 2.87% | 346,075 | $57M | $163.52 | $29M | +189,274 | +120.7% | |
| 11 | ALC | 2.79% | 729,972 | $55M | $75.35 | $29M | +397,452 | +119.5% | |
| 12 | SUPN | 2.50% | 954,309 | $49M | $51.69 | $22M | +401,214 | +72.5% | |
| 13 | BMRN | 2.24% | 781,982 | $44M | $56.49 | $3M | +84,849 | +12.2% | |
| 14 | BIIB | 2.13% | 229,521 | $42M | $183.33 | — | +229,521 | — | NEW |
| 15 | CELC | 2.12% | 366,175 | $42M | $114.14 | $12M | +66,758 | +22.3% | |
| 16 | BIOA | 2.03% | 2,293,788 | $40M | $17.49 | $10M | — | — | |
| 17 | RYTM | 1.99% | 450,096 | $39M | $86.97 | $10M | +178,702 | +65.8% | |
| 18 | AVBP | 1.99% | 1,696,752 | $39M | $23.07 | $5M | — | — | |
| 19 | IDYA | 1.91% | 1,131,786 | $38M | $33.32 | $7M | +246,665 | +27.9% | |
| 20 | IMNM | 1.89% | 1,701,904 | $37M | $21.87 | $2M | +83,427 | +5.2% | |
| 21 | NKTR | 1.86% | 509,546 | $37M | $71.95 | $18M | +70,916 | +16.2% | |
| 22 | AXSM | 1.82% | 212,747 | $36M | $169.02 | $34M | +200,481 | +1634.4% | |
| 23 | IMTX | 1.81% | 3,630,454 | $36M | $9.84 | -$350K | +194,912 | +5.7% | |
| 24 | BBIO | 1.54% | 409,183 | $30M | $74.26 | -$25M | -311,265 | -43.2% | |
| 25 | DYN | 1.50% | 1,633,897 | $30M | $18.13 | -$14M | -620,264 | -27.5% | |
| 26 | INBX | 1.38% | 406,029 | $27M | $67.23 | -$9M | -48,628 | -10.7% | |
| 27 | DXCM | 1.25% | 393,576 | $25M | $62.80 | -$386K | +15,357 | +4.1% | |
| 28 | PRAX | 1.04% | 63,680 | $21M | $322.19 | -$17M | -62,042 | -49.4% | |
| 29 | GMAB | 1.02% | 752,261 | $20M | $26.83 | — | +752,261 | — | NEW |
| 30 | RCUS | 1.01% | 923,086 | $20M | $21.60 | -$6M | -173,619 | -15.8% | |
| 31 | XENE | 0.90% | 305,216 | $18M | $58.15 | $15M | +245,316 | +409.5% | |
| 32 | SYK | 0.74% | 44,480 | $15M | $328.59 | — | +44,480 | — | NEW |
| 33 | ANAB | 0.70% | 248,253 | $14M | $55.46 | -$179K | -39,437 | -13.7% | |
| 34 | ROIV | 0.67% | 477,995 | $13M | $27.70 | -$3M | -256,587 | -34.9% | |
| 35 | EWTX | 0.62% | 386,498 | $12M | $31.50 | $1M | -51,321 | -11.7% | |
| 36 | CMPX | 0.55% | 2,056,161 | $11M | $5.29 | -$7M | -1,309,285 | -38.9% | |
| 37 | ORIC | 0.44% | 679,578 | $9M | $12.67 | — | +679,578 | — | NEW |
| 38 | TNGX | 0.42% | 395,081 | $8M | $20.92 | — | +395,081 | — | NEW |
| 39 | TYRA | 0.40% | 204,015 | $8M | $38.30 | — | +204,015 | — | NEW |
| 40 | AXGN | 0.35% | 210,665 | $7M | $33.13 | — | +210,665 | — | NEW |
| 41 | DFTX | 0.33% | 344,166 | $7M | $18.90 | — | +344,166 | — | NEW |
| 42 | CYTK | 0.31% | 91,791 | $6M | $65.91 | — | +91,791 | — | NEW |
| 43 | IRON | 0.25% | 78,320 | $5M | $63.94 | -$4M | -32,690 | -29.4% | |
| 44 | MANE | 0.23% | 73,315 | $5M | $63.15 | — | +73,315 | — | NEW |
| 45 | HRMY | 0.22% | 152,695 | $4M | $28.01 | — | +152,695 | — | NEW |
| 46 | PCVX | 0.15% | 50,600 | $3M | $58.11 | — | +50,600 | — | NEW |
| 47 | MIRM | 0.13% | 27,591 | $3M | $92.38 | $724K | +4,491 | +19.4% | |
| 48 | NXTC | 0.12% | 222,654 | $2M | $10.68 | -$782K | — | — | |
| 49 | SVRA | 0.10% | 364,763 | $2M | $5.46 | $154K | +59,993 | +19.7% | |
| 50 | ESTA | 0.10% | 33,930 | $2M | $56.78 | -$141K | +5,564 | +19.6% | |
| 51 | ACAD | 0.09% | 78,551 | $2M | $22.26 | -$3K | +12,984 | +19.8% | |
| 52 | TENX | 0.08% | 104,400 | $2M | $15.99 | — | +104,400 | — | NEW |
| 53 | JBIO | 0.08% | 107,391 | $2M | $14.05 | -$148K | — | — | |
| 54 | SEPN | 0.06% | 47,506 | $1M | $24.03 | — | +47,506 | — | NEW |
| 55 | OKUR | 0.03% | 141,700 | $587K | $4.14 | — | +141,700 | — | NEW |
| 56 | BOLT | 0.03% | 137,721 | $556K | $4.04 | -$197K | — | — | |
| 57 | SLNO | 0.02% | 14,689 | $492K | $33.48 | -$83K | +2,275 | +18.3% | |
| 58 | IMA | 0.01% | 31,884 | $159K | $5.00 | -$61K | — | — | |
| 59 | ZYME | —% | 1,610 | $40K | $25.04 | — | +1,610 | — | NEW |
| 60 | GEHC | —% | — | — | — | -$13M | -160,876 | -100.0% | SOLD |
| 61 | GKOS | —% | — | — | — | -$33M | -288,128 | -100.0% | SOLD |
| 62 | MASI | —% | — | — | — | -$6M | -46,201 | -100.0% | SOLD |
| 63 | EVMN | —% | — | — | — | -$3M | -153,320 | -100.0% | SOLD |
| 64 | LLY | —% | — | — | — | -$66M | -61,652 | -100.0% | SOLD |
| 65 | VRTX | —% | — | — | — | -$75M | -164,594 | -100.0% | SOLD |
| 66 | ABBV | —% | — | — | — | -$73M | -317,783 | -100.0% | SOLD |
| 67 | ISRG | —% | — | — | — | -$72M | -126,968 | -100.0% | SOLD |
| 68 | EXAS | —% | — | — | — | -$10M | -101,443 | -100.0% | SOLD |
| 69 | AMLX | —% | — | — | — | -$6M | -527,099 | -100.0% | SOLD |
| 70 | APGE | —% | — | — | — | -$40M | -534,845 | -100.0% | SOLD |
| 71 | CNTA | —% | — | — | — | -$28M | -1,104,274 | -100.0% | SOLD |
| 72 | RNAM | —% | — | — | — | -$54M | -745,116 | -100.0% | SOLD |
| 73 | CDTX | —% | — | — | — | -$40M | -180,265 | -100.0% | SOLD |
Options Breakdown
4 Calls
$40M Call Value
9 Puts
$595M Put Value
14.8 P/C Ratio