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Also trades as: 0T6G.L (LSE) · $vol 0M

QTTB Institutional Ownership

Q32 Bio Inc.
1W: +1.0% 1M: -5.6% 3M: -40.5% YTD: +153.2% 1Y: +193.3% 3Y: -53.0% 5Y: -92.1%
$8.71
+0.26 (+3.08%)
 
Weekly Expected Move ±11.2%
$7 $8 $9 $10 $11
NASDAQ · Healthcare · Biotechnology · Tech Score Sell · Power 45 · $259.3M mcap · 13M float · 8.77% daily turnover · Short 51% of daily vol
Credit Risk of going bust: higher than 79% of companies Debt: 2.0% of company value Bonds: none of note held by US funds details ▾
Of US companies ranked in the third-riskiest tenth, about 1 in 140 filed for bankruptcy within a year (2020-2025).
If the stock fell to about $0.04 (down 99.5%), Q32 Bio Inc. would be worth roughly what it owes.
Total debt $5.3M against a stock market value of $259.3M.
Distance to default 2.72 (Merton model): prices to 2026-10-27, balance sheet 2026-06-30, debt counted $2.3M (short-term plus half of long-term), stock volatility 141.2%; Altman Z'' 12.11. A ranking and a back-test, not a forecast.
US fund filings (SEC N-PORT) show under $25M of this company's bonds, so there is no bond page. Its debt may be bank loans or privately placed. How these are computed.

Institutional Ownership — QTTB

80
Institutional Holders
+19 vs prior quarter
0.0%
Ownership
+0.00pp
$280M
Total Invested
28
New Positions
17
Increased
22
Reduced
9
Closed
0.00
Put/Call Ratio

Ownership Trends

Top Institutional Holders (86 total)

# Holder Shares Value Change Change % Holding Period Filing
1 ORBIMED ADVISORS LLC 4,127,987 $36M +1,875,000 +83.2% 10Q SEC ↗
2 Boxer Capital Management, LLC NEW 3,149,310 $27M — +0.0% 1Q SEC ↗
3 Atlas Venture Life Science Advisors, L 2,717,106 $24M +625,000 +29.9% 10Q SEC ↗
4 BVF INC/IL NEW 2,350,000 $20M — +0.0% 1Q SEC ↗
5 RA CAPITAL MANAGEMENT, L.P. NEW 2,332,457 $20M — +0.0% 1Q SEC ↗
6 Point72 Asset Management, L.P. NEW 1,173,396 $10M — +0.0% 1Q SEC ↗
7 Opaleye Management Inc. 931,000 $8M -325,228 -25.9% 3Q SEC ↗
8 Logos Global Management LP NEW 800,000 $7M — +0.0% 1Q SEC ↗
9 SummitTX Capital, L.P. NEW 733,774 $6M — +0.0% 1Q SEC ↗
10 VANGUARD CAPITAL MANAGEMENT LLC 518,803 $5M +212,402 +69.3% 2Q SEC ↗
11 Ikarian Capital, LLC NEW 430,000 $4M — +0.0% 1Q SEC ↗
12 Woodline Partners LP NEW 286,212 $2M — +0.0% 1Q SEC ↗
13 AMERICAN CENTURY COMPANIES INC 272,752 $2M +253,982 +1353.1% 2Q SEC ↗
14 Sanofi 244,083 $2M — +0.0% 7Q SEC ↗
15 ACADIAN ASSET MANAGEMENT LLC 218,234 $2M +45,648 +26.4% 6Q SEC ↗
16 ACORN CAPITAL ADVISORS, LLC 216,171 $2M -98,881 -31.4% 7Q SEC ↗
17 RENAISSANCE TECHNOLOGIES LLC 179,600 $2M -27,315 -13.2% 5Q SEC ↗
18 JANE STREET GROUP, LLC 162,747 $1M +97,148 +148.1% 3Q SEC ↗
19 MONIMUS CAPITAL MANAGEMENT, LP 132,036 $1M -2,274 -1.7% 2Q SEC ↗
20 BOOTHBAY FUND MANAGEMENT, LLC NEW 130,427 $1M — +0.0% 1Q SEC ↗
21 GEODE CAPITAL MANAGEMENT, LLC 122,690 $1M +4,538 +3.8% 10Q SEC ↗
22 CITADEL ADVISORS LLC 120,663 $1M +105,182 +679.4% 4Q SEC ↗
23 BlackRock, Inc. 118,507 $1M +32,360 +37.6% 8Q SEC ↗
24 MARSHALL WACE, LLP 67,045 $584K +14,605 +27.9% 2Q SEC ↗
25 VANGUARD FIDUCIARY TRUST CO 66,217 $577K +16,222 +32.4% 2Q SEC ↗
26 Carlyle Group Inc. 60,363 $526K -1,042,378 -94.5% 10Q SEC ↗
27 STATE STREET CORP 52,214 $455K +10,700 +25.8% 9Q SEC ↗
28 TWO SIGMA INVESTMENTS, LP 49,582 $432K +7,236 +17.1% 4Q SEC ↗
29 Quadrature Capital Ltd NEW 36,396 $317K — +0.0% 1Q SEC ↗
30 BRIDGEWAY CAPITAL MANAGEMENT, LLC 34,613 $301K +22,000 +174.4% 2Q SEC ↗
31 DAFNA Capital Management LLC NEW 32,896 $287K — +0.0% 1Q SEC ↗
32 Knott David M Jr NEW 30,412 $265K — +0.0% 1Q SEC ↗
33 Affinity Asset Advisors, LLC 27,777 $242K — +0.0% 10Q SEC ↗
34 Squarepoint Ops LLC NEW 23,790 $207K — +0.0% 1Q SEC ↗
35 NORTHERN TRUST CORP 23,631 $206K -1,402 -5.6% 8Q SEC ↗
36 DIMENSIONAL FUND ADVISORS LP NEW 23,588 $205K — +0.0% 1Q SEC ↗
37 SUSQUEHANNA INTERNATIONAL GROUP, LLP NEW 23,342 $203K — +0.0% 1Q SEC ↗
38 MANGROVE PARTNERS IM, LLC NEW 22,150 $193K — +0.0% 1Q SEC ↗
39 LPL Financial LLC NEW 18,170 $158K — +0.0% 1Q SEC ↗
40 Cambridge Investment Research Advisors 18,081 $157K -16,944 -48.4% 2Q SEC ↗
41 HRT FINANCIAL LP NEW 15,949 $139K — +0.0% 1Q SEC ↗
42 UBS Group AG 15,008 $131K +14,738 +5458.5% 10Q SEC ↗
43 Balyasny Asset Management L.P. NEW 12,342 $107K — +0.0% 1Q SEC ↗
44 ExodusPoint Capital Management, LP NEW 11,336 $99K — +0.0% 1Q SEC ↗
45 MILLENNIUM MANAGEMENT LLC NEW 10,928 $95K — +0.0% 1Q SEC ↗
46 XTX Topco Ltd NEW 10,874 $95K — +0.0% 1Q SEC ↗
47 MORGAN STANLEY 6,456 $56K -3,104 -32.5% 10Q SEC ↗
48 Vanguard Global Advisers, LLC 4,824 $42K +2,909 +151.9% 2Q SEC ↗
49 FMR LLC 3,388 $30K -12 -0.4% 10Q SEC ↗
50 CITIGROUP INC NEW 2,888 $25K — +0.0% 1Q SEC ↗

Recent Activity

Biggest Increases (17)
HolderAddedChange %Total Shares
ORBIMED ADVISORS LLC +1,875,000 +83.2% 4,127,987
Atlas Venture Life Science Advisors +625,000 +29.9% 2,717,106
AMERICAN CENTURY COMPANIES INC +253,982 +1353.1% 272,752
VANGUARD CAPITAL MANAGEMENT LLC +212,402 +69.3% 518,803
CITADEL ADVISORS LLC +105,182 +679.4% 120,663
JANE STREET GROUP, LLC +97,148 +148.1% 162,747
ACADIAN ASSET MANAGEMENT LLC +45,648 +26.4% 218,234
BlackRock, Inc. +32,360 +37.6% 118,507
BRIDGEWAY CAPITAL MANAGEMENT, LLC +22,000 +174.4% 34,613
VANGUARD FIDUCIARY TRUST CO +16,222 +32.4% 66,217
UBS Group AG +14,738 +5458.5% 15,008
MARSHALL WACE, LLP +14,605 +27.9% 67,045
STATE STREET CORP +10,700 +25.8% 52,214
TWO SIGMA INVESTMENTS, LP +7,236 +17.1% 49,582
GEODE CAPITAL MANAGEMENT, LLC +4,538 +3.8% 122,690
Vanguard Global Advisers, LLC +2,909 +151.9% 4,824
Allworth Financial LP +10 +10.2% 108
Biggest Decreases (13)
HolderReducedChange %Total Shares
Carlyle Group Inc. -1,042,378 -94.5% 60,363
Opaleye Management Inc. -325,228 -25.9% 931,000
ACORN CAPITAL ADVISORS, LLC -98,881 -31.4% 216,171
RENAISSANCE TECHNOLOGIES LLC -27,315 -13.2% 179,600
Cambridge Investment Research Advis -16,944 -48.4% 18,081
EverSource Wealth Advisors, LLC -4,400 -94.8% 240
MORGAN STANLEY -3,104 -32.5% 6,456
MONIMUS CAPITAL MANAGEMENT, LP -2,274 -1.7% 132,036
NORTHERN TRUST CORP -1,402 -5.6% 23,631
FEDERATED HERMES, INC. -1,223 -53.8% 1,050
Arax Advisory Partners -37 -3.2% 1,111
FMR LLC -12 -0.4% 3,388
SBI Securities Co., Ltd. -10 -9.6% 94

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For informational purposes only. Not investment advice. Data sourced from SEC filings. Privacy Terms