UPB Smart Money
Upstream Bio, Inc.
1W: -6.0%
1M: -22.2%
3M: -31.9%
YTD: -80.7%
1Y: -70.9%
$5.04
+0.00 (+0.00%)
Weekly Expected Move ±6.0%
$4
$5
$5
$5
$6
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🏦 Institutional Activity
Latest: Q2 2026178
Institutions Holding
+0 vs prior
127.8%
Ownership
-19.63%
39
New
64
Increased
55
Reduced
27
Closed
👔 Insider Trades
16 records| Date | Name | Title | Type | Shares | Price | Value | Filing |
|---|---|---|---|---|---|---|---|
| 2026-09-16 | GRAY MICHAEL | officer: cfo and coo | S-Sale | 853 | $5.49 | $5K | Filing |
| 2026-09-16 | Ambrose Allison | officer: general counsel | S-Sale | 485 | $5.49 | $3K | Filing |
| 2026-09-16 | Deykin Aaron | officer: chief medical officer | S-Sale | 895 | $5.49 | $5K | Filing |
| 2026-09-16 | Sutherland Everett Rand | officer: chief executive officer | S-Sale | 2,095 | $5.49 | $12K | Filing |
| 2026-09-16 | Houghton Adam | officer: chief business officer | S-Sale | 700 | $5.49 | $4K | Filing |
| 2026-06-16 | GRAY MICHAEL | officer: cfo and coo | S-Sale | 853 | $6.10 | $5K | Filing |
| 2026-06-16 | Sutherland Everett Rand | officer: chief executive officer | S-Sale | 2,095 | $6.10 | $13K | Filing |
| 2026-06-16 | Houghton Adam | officer: chief business officer | S-Sale | 700 | $6.10 | $4K | Filing |
| 2026-06-16 | Deykin Aaron | officer: chief medical officer | S-Sale | 895 | $6.10 | $5K | Filing |
| 2026-06-16 | Ambrose Allison | officer: general counsel | S-Sale | 477 | $6.10 | $3K | Filing |
| 2026-03-16 | Houghton Adam | officer: chief business officer | S-Sale | 699 | $9.29 | $6K | Filing |
| 2026-01-02 | Ambrose Allison | officer: general counsel | A-Grant/Award | 17,000 | $— | $0 | Filing |
| 2026-01-02 | Deykin Aaron | officer: chief medical officer | A-Grant/Award | 32,000 | $— | $0 | Filing |
| 2026-01-02 | GRAY MICHAEL | officer: cfo and coo | A-Grant/Award | 30,500 | $— | $0 | Filing |
| 2026-01-02 | Houghton Adam | officer: chief business officer | A-Grant/Award | 25,000 | $— | $0 | Filing |
| 2026-01-02 | Sutherland Everett Rand | officer: chief executive officer | A-Grant/Award | 75,000 | $— | $0 | Filing |
🏛️ Congressional Trades
0 records| Date | Politician | Chamber | Type | Amount | Filing |
|---|---|---|---|---|---|
| No congressional trades found | |||||
🏦 Top Institutional Holders
20 holders| Holder | Shares | Value | Date Reported | Filing | |
|---|---|---|---|---|---|
| FMR LLC | 8,162,897 | $56M | +61,334 | 2026-06-30 | Filing |
| ORBIMED ADVISORS LLC | 5,693,589 | $39M | — | 2026-06-30 | Filing |
| NORGES BANK | 3,768,619 | $26M | +3,768,619 | 2026-06-30 | Filing |
| BlackRock, Inc. | 3,753,358 | $26M | +382,669 | 2026-06-30 | Filing |
| Decheng Capital LLC | 2,724,868 | $19M | — | 2026-06-30 | Filing |
| ENAVATE SCIENCES GP, LLC | 2,459,703 | $17M | — | 2026-06-30 | Filing |
| VANGUARD CAPITAL MANAGEMENT LLC | 1,876,734 | $13M | +3,160 | 2026-06-30 | Filing |
| MILLENNIUM MANAGEMENT LLC | 1,143,775 | $8M | +206,452 | 2026-06-30 | Filing |
| D. E. Shaw & Co., Inc. | 1,036,044 | $7M | +215,564 | 2026-06-30 | Filing |
| JPMORGAN CHASE & CO | 1,012,044 | $7M | +549,043 | 2026-06-30 | Filing |
| Qube Research & Technologies Ltd | 978,500 | $7M | +359,179 | 2026-06-30 | Filing |
| Parkman Healthcare Partners LLC | 935,247 | $6M | +148,464 | 2026-06-30 | Filing |
| GEODE CAPITAL MANAGEMENT, LLC | 931,261 | $6M | -19,356 | 2026-06-30 | Filing |
| SEB Asset Management AB | 878,473 | $6M | — | 2026-06-30 | Filing |
| Woodline Partners LP | 831,481 | $6M | — | 2026-06-30 | Filing |
| STATE STREET CORP | 766,323 | $5M | +60,973 | 2026-06-30 | Filing |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 712,667 | $5M | -15,044 | 2026-06-30 | Filing |
| Y-Intercept (Hong Kong) Ltd | 693,555 | $5M | -307,076 | 2026-06-30 | Filing |
| Bain Capital Life Sciences Investors, LL | 600,949 | $4M | -266,262 | 2026-06-30 | Filing |
| AQR CAPITAL MANAGEMENT LLC | 544,869 | $4M | +472,698 | 2026-06-30 | Filing |