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UPB NASDAQ

Upstream Bio, Inc.
1W: -3.8% 1M: -12.2% 3M: +4.7% YTD: -67.6% 1Y: +11.6%
$8.37
-0.09 (-1.06%)
 
Weekly Expected Move ±7.0%
$8 $8 $9 $10 $10
NASDAQ · Healthcare · Biotechnology · Alpha Radar Sell · Power 31 · $455.5M mcap · 20M float · 3.99% daily turnover · Short 30% of daily vol

🏦 Institutional Activity

Latest: Q1 2026
177
Institutions Holding
+32 vs prior
78.2%
Ownership
-226.68%
42 New
42 Increased
84 Reduced
53 Closed

👔 Insider Trades

6 records
Date Name Title Type Shares Price Value Filing
2026-03-16 Houghton Adam officer: chief business officer S-Sale 699 $9.29 $6K Filing
2026-01-02 Ambrose Allison officer: general counsel A-Grant/Award 17,000 $— $0 Filing
2026-01-02 Deykin Aaron officer: chief medical officer A-Grant/Award 32,000 $— $0 Filing
2026-01-02 GRAY MICHAEL officer: cfo and coo A-Grant/Award 30,500 $— $0 Filing
2026-01-02 Houghton Adam officer: chief business officer A-Grant/Award 25,000 $— $0 Filing
2026-01-02 Sutherland Everett Rand officer: chief executive officer A-Grant/Award 75,000 $— $0 Filing

🏛️ Congressional Trades

0 records
Date Politician Chamber Type Amount Filing
No congressional trades found

🏦 Top Institutional Holders

20 holders
Holder Shares Value Date Reported Filing
FMR LLC 8,101,563 $73M +583,361 2026-03-31 Filing
ORBIMED ADVISORS LLC 5,693,589 $51M 2026-03-31 Filing
BlackRock, Inc. 3,370,689 $30M +26,185 2026-03-31 Filing
Decheng Capital LLC 2,724,868 $25M -418,210 2026-03-31 Filing
ENAVATE SCIENCES GP, LLC 2,459,703 $22M 2026-03-31 Filing
VANGUARD CAPITAL MANAGEMENT LLC 1,873,574 $17M +1,873,574 2026-03-31 Filing
Y-Intercept (Hong Kong) Ltd 1,000,631 $9M +954,072 2026-03-31 Filing
GEODE CAPITAL MANAGEMENT, LLC 950,617 $9M +98,709 2026-03-31 Filing
SEB Asset Management AB 878,473 $8M +878,473 2026-03-31 Filing
Bain Capital Life Sciences Investors, LL 867,211 $8M -462,333 2026-03-31 Filing
Woodline Partners LP 831,481 $7M +71,229 2026-03-31 Filing
Parkman Healthcare Partners LLC 786,783 $7M -47,776 2026-03-31 Filing
Pictet Asset Management Holding SA 733,431 $7M -39,717 2026-03-31 Filing
VANGUARD PORTFOLIO MANAGEMENT LLC 727,711 $7M +727,711 2026-03-31 Filing
STATE STREET CORP 705,350 $6M -613,876 2026-03-31 Filing
HSBC HOLDINGS PLC 640,326 $6M +640,326 2026-03-31 Filing
Qube Research & Technologies Ltd 619,321 $6M +619,321 2026-03-31 Filing
JPMORGAN CHASE & CO 463,001 $4M +352,721 2026-03-31 Filing
Altshuler Shaham Ltd 380,061 $3M -961,479 2026-03-31 Filing
Propel Bio Management, LLC 341,779 $3M +341,779 2026-03-31 Filing

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For informational purposes only. Not investment advice. Data sourced from SEC filings. Privacy Terms