DFTX Institutional Ownership
Definium Therapeutics, Inc.
1W: +3.4%
1M: -3.9%
3M: -15.6%
YTD: +174.2%
$37.40
-0.20 (-0.53%)
Weekly Expected Move ±7.4%
$32
$35
$37
$40
$43
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Institutional Ownership — DFTX
399
Institutional Holders
+148 vs prior quarter
0.0%
Ownership
+0.00pp
$5B
Total Invested
151
New Positions
115
Increased
95
Reduced
31
Closed
0.80
Put/Call Ratio
Ownership Trends
Top Institutional Holders (398 total)
| # | Holder | Shares | Value | Change | Change % | Holding Period | Filing |
|---|---|---|---|---|---|---|---|
| 1 | BlackRock, Inc. | 11,232,834 | $420M | +2,752,604 | +32.5% | 2Q | SEC ↗ |
| 2 | Avoro Capital Advisors LLC | 7,188,888 | $269M | +2,188,888 | +43.8% | 2Q | SEC ↗ |
| 3 | Driehaus Capital Management LLC | 6,845,276 | $256M | +933,387 | +15.8% | 3Q | SEC ↗ |
| 4 | Jupiter Topco LLC NEW | 5,615,645 | $210M | — | +0.0% | 1Q | SEC ↗ |
| 5 | Capital World Investors NEW | 5,367,723 | $201M | — | +0.0% | 1Q | SEC ↗ |
| 6 | FMR LLC | 4,752,921 | $178M | +2,943,311 | +162.6% | 2Q | SEC ↗ |
| 7 | PRICE T ROWE ASSOCIATES INC /MD | 4,652,032 | $174M | +4,582,031 | +6545.7% | 3Q | SEC ↗ |
| 8 | GEODE CAPITAL MANAGEMENT, LLC | 3,644,813 | $136M | +1,149,414 | +46.1% | 2Q | SEC ↗ |
| 9 | JANUS HENDERSON GROUP PLC NEW | 3,556,041 | $133M | — | +0.0% | 1Q | SEC ↗ |
| 10 | STATE STREET CORP | 3,065,390 | $115M | +593,517 | +24.0% | 2Q | SEC ↗ |
| 11 | Capital International Investors NEW | 2,963,410 | $111M | — | +0.0% | 1Q | SEC ↗ |
| 12 | Octagon Capital Advisors LP | 2,950,000 | $110M | +510,000 | +20.9% | 2Q | SEC ↗ |
| 13 | WELLINGTON MANAGEMENT GROUP LLP | 2,949,734 | $110M | +1,644,985 | +126.1% | 2Q | SEC ↗ |
| 14 | Deep Track Capital, LP | 2,750,000 | $103M | -250,000 | -8.3% | 2Q | SEC ↗ |
| 15 | Commodore Capital LP | 2,000,000 | $75M | — | +0.0% | 2Q | SEC ↗ |
| 16 | ALLIANCEBERNSTEIN L.P. | 1,803,287 | $67M | +1,711,584 | +1866.4% | 2Q | SEC ↗ |
| 17 | GOLDMAN SACHS GROUP INC | 1,800,852 | $67M | +125,441 | +7.5% | 2Q | SEC ↗ |
| 18 | CITADEL ADVISORS LLC | 1,688,587 | $63M | +355,145 | +26.6% | 2Q | SEC ↗ |
| 19 | VANGUARD PORTFOLIO MANAGEMENT LLC | 1,648,426 | $62M | +775,761 | +88.9% | 2Q | SEC ↗ |
| 20 | RA CAPITAL MANAGEMENT, L.P. NEW | 1,500,000 | $56M | — | +0.0% | 1Q | SEC ↗ |
| 21 | VANGUARD CAPITAL MANAGEMENT LLC | 1,486,454 | $56M | +389,476 | +35.5% | 2Q | SEC ↗ |
| 22 | Siren, L.L.C. | 1,419,493 | $53M | +500,000 | +54.4% | 2Q | SEC ↗ |
| 23 | MARSHALL WACE, LLP | 1,298,946 | $49M | +98,121 | +8.2% | 3Q | SEC ↗ |
| 24 | NORTHERN TRUST CORP | 1,169,238 | $44M | +370,251 | +46.3% | 2Q | SEC ↗ |
| 25 | AMERIPRISE FINANCIAL INC | 1,148,363 | $43M | +181,755 | +18.8% | 2Q | SEC ↗ |
| 26 | Nuveen, LLC | 1,105,314 | $41M | +407,184 | +58.3% | 2Q | SEC ↗ |
| 27 | CHARLES SCHWAB INVESTMENT MANAGEMENT I | 1,083,576 | $41M | +274,861 | +34.0% | 2Q | SEC ↗ |
| 28 | Sixth Street Partners Management Compa NEW | 1,083,576 | $41M | — | +0.0% | 1Q | SEC ↗ |
| 29 | Woodline Partners LP | 1,003,641 | $38M | +250,849 | +33.3% | 2Q | SEC ↗ |
| 30 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 1,000,000 | $37M | -150,000 | -13.0% | 2Q | SEC ↗ |
| 31 | Boxer Capital Management, LLC | 998,500 | $37M | +400,000 | +66.8% | 2Q | SEC ↗ |
| 32 | TWO SIGMA INVESTMENTS, LP | 921,818 | $34M | -279,792 | -23.3% | 2Q | SEC ↗ |
| 33 | Balyasny Asset Management L.P. | 897,658 | $34M | -376,563 | -29.6% | 2Q | SEC ↗ |
| 34 | VANGUARD FIDUCIARY TRUST CO | 827,693 | $31M | +251,756 | +43.7% | 2Q | SEC ↗ |
| 35 | Holocene Advisors, LP | 796,574 | $30M | -295,393 | -27.1% | 2Q | SEC ↗ |
| 36 | AWM Investment Company, Inc. | 784,800 | $29M | -292,093 | -27.1% | 3Q | SEC ↗ |
| 37 | Bank of New York Mellon Corp | 777,271 | $29M | +24,349 | +3.2% | 2Q | SEC ↗ |
| 38 | Polar Capital Holdings Plc NEW | 777,253 | $29M | — | +0.0% | 1Q | SEC ↗ |
| 39 | EVENTIDE ASSET MANAGEMENT, LLC | 710,000 | $27M | +23,838 | +3.5% | 2Q | SEC ↗ |
| 40 | NEUBERGER BERMAN GROUP LLC | 687,539 | $26M | +554,170 | +415.5% | 2Q | SEC ↗ |
| 41 | Qube Research & Technologies Ltd | 682,901 | $26M | +256,846 | +60.3% | 2Q | SEC ↗ |
| 42 | Candriam S.C.A. | 614,425 | $23M | -679,204 | -52.5% | 2Q | SEC ↗ |
| 43 | ArrowMark Colorado Holdings LLC | 564,069 | $21M | -1,030,648 | -64.6% | 2Q | SEC ↗ |
| 44 | Catalio Capital Management, LP | 562,672 | $21M | -475,312 | -45.8% | 2Q | SEC ↗ |
| 45 | Blackstone Inc. | 561,612 | $21M | +52,944 | +10.4% | 2Q | SEC ↗ |
| 46 | Integral Health Asset Management, LLC | 550,000 | $21M | +150,000 | +37.5% | 2Q | SEC ↗ |
| 47 | BAMCO INC /NY NEW | 520,108 | $19M | — | +0.0% | 1Q | SEC ↗ |
| 48 | UBS Group AG | 499,467 | $19M | +5,490 | +1.1% | 2Q | SEC ↗ |
| 49 | FRANKLIN RESOURCES INC NEW | 486,219 | $18M | — | +0.0% | 1Q | SEC ↗ |
| 50 | Point72 Asset Management, L.P. | 483,980 | $18M | +308,490 | +175.8% | 2Q | SEC ↗ |
Recent Activity
New Positions (20)
| Holder | Shares | Value |
|---|---|---|
| Jupiter Topco LLC | 5,615,645 | $210M |
| Capital World Investors | 5,367,723 | $201M |
| JANUS HENDERSON GROUP PLC | 3,556,041 | $133M |
| Capital International Investors | 2,963,410 | $111M |
| RA CAPITAL MANAGEMENT, L.P. | 1,500,000 | $56M |
| Sixth Street Partners Management Co | 1,083,576 | $41M |
| Polar Capital Holdings Plc | 777,253 | $29M |
| BAMCO INC /NY | 520,108 | $19M |
| FRANKLIN RESOURCES INC | 486,219 | $18M |
| GREAT POINT PARTNERS LLC | 425,000 | $16M |
| SILVERARC CAPITAL MANAGEMENT, LLC | 400,000 | $15M |
| Cormorant Asset Management, LP | 400,000 | $15M |
| ASSETMARK, INC | 396,542 | $15M |
| Duquesne Family Office LLC | 356,600 | $13M |
| Trexquant Investment LP | 233,199 | $9M |
| TD Asset Management Inc | 209,460 | $8M |
| SEB Asset Management AB | 208,254 | $8M |
| EMERALD ADVISERS, LLC | 178,751 | $7M |
| Aberdeen Group plc | 175,000 | $7M |
| LMR Partners LLP | 150,200 | $6M |
Sold Out (20)
| Holder | Prev Shares | Prev Value |
|---|---|---|
| Trails Edge Capital Partners, LP | 1,738,110 | $65M |
| Patient Square Capital LP | 331,000 | $12M |
| JANE STREET GROUP, LLC | 260,241 | $10M |
| Soviero Asset Management, LP | 140,000 | $5M |
| Squarepoint Ops LLC | 125,522 | $5M |
| Rosalind Advisors, Inc. | 125,000 | $5M |
| ExodusPoint Capital Management, LP | 104,915 | $4M |
| HRT FINANCIAL LP | 89,141 | $3M |
| Ikarian Capital, LLC | 58,803 | $2M |
| TWINBEECH CAPITAL LP | 42,100 | $2M |
| CAXTON ASSOCIATES LLP | 37,255 | $1M |
| DARK FOREST CAPITAL MANAGEMENT LP | 30,661 | $1M |
| Campbell & CO Investment Adviser LL | 24,755 | $926K |
| FOX RUN MANAGEMENT, L.L.C. | 14,557 | $544K |
| Virtu Financial LLC | 14,460 | $541K |
| BOOTHBAY FUND MANAGEMENT, LLC | 14,096 | $527K |
| Magnetar Financial LLC | 13,178 | $493K |
| Summit Trail Advisors, LLC | 13,000 | $486K |
| RPS ADVISORY SOLUTIONS LLC | 11,355 | $425K |
| Dynamic Technology Lab Private Ltd | 10,880 | $407K |
Biggest Increases (20)
| Holder | Added | Change % | Total Shares |
|---|---|---|---|
| PRICE T ROWE ASSOCIATES INC /MD | +4,582,031 | +6545.7% | 4,652,032 |
| FMR LLC | +2,943,311 | +162.6% | 4,752,921 |
| BlackRock, Inc. | +2,752,604 | +32.5% | 11,232,834 |
| Avoro Capital Advisors LLC | +2,188,888 | +43.8% | 7,188,888 |
| ALLIANCEBERNSTEIN L.P. | +1,711,584 | +1866.4% | 1,803,287 |
| WELLINGTON MANAGEMENT GROUP LLP | +1,644,985 | +126.1% | 2,949,734 |
| GEODE CAPITAL MANAGEMENT, LLC | +1,149,414 | +46.1% | 3,644,813 |
| Driehaus Capital Management LLC | +933,387 | +15.8% | 6,845,276 |
| VANGUARD PORTFOLIO MANAGEMENT LLC | +775,761 | +88.9% | 1,648,426 |
| STATE STREET CORP | +593,517 | +24.0% | 3,065,390 |
| NEUBERGER BERMAN GROUP LLC | +554,170 | +415.5% | 687,539 |
| Octagon Capital Advisors LP | +510,000 | +20.9% | 2,950,000 |
| Siren, L.L.C. | +500,000 | +54.4% | 1,419,493 |
| Nuveen, LLC | +407,184 | +58.3% | 1,105,314 |
| Boxer Capital Management, LLC | +400,000 | +66.8% | 998,500 |
| VANGUARD CAPITAL MANAGEMENT LLC | +389,476 | +35.5% | 1,486,454 |
| NORTHERN TRUST CORP | +370,251 | +46.3% | 1,169,238 |
| CITADEL ADVISORS LLC | +355,145 | +26.6% | 1,688,587 |
| Point72 Asset Management, L.P. | +308,490 | +175.8% | 483,980 |
| CHARLES SCHWAB INVESTMENT MANAGEMEN | +274,861 | +34.0% | 1,083,576 |
Biggest Decreases (20)
| Holder | Reduced | Change % | Total Shares |
|---|---|---|---|
| ArrowMark Colorado Holdings LLC | -1,030,648 | -64.6% | 564,069 |
| Candriam S.C.A. | -679,204 | -52.5% | 614,425 |
| MILLENNIUM MANAGEMENT LLC | -580,820 | -68.6% | 266,076 |
| Catalio Capital Management, LP | -475,312 | -45.8% | 562,672 |
| ORBIMED ADVISORS LLC | -438,600 | -54.6% | 365,400 |
| Balyasny Asset Management L.P. | -376,563 | -29.6% | 897,658 |
| Holocene Advisors, LP | -295,393 | -27.1% | 796,574 |
| AWM Investment Company, Inc. | -292,093 | -27.1% | 784,800 |
| TWO SIGMA INVESTMENTS, LP | -279,792 | -23.3% | 921,818 |
| DEUTSCHE BANK AG | -268,887 | -65.3% | 142,947 |
| Deep Track Capital, LP | -250,000 | -8.3% | 2,750,000 |
| Tri Locum Partners LP | -206,592 | -55.9% | 162,996 |
| STEMPOINT CAPITAL LP | -188,359 | -57.9% | 137,124 |
| SUPERSTRING CAPITAL MANAGEMENT LP | -163,179 | -46.4% | 188,282 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | -150,000 | -13.0% | 1,000,000 |
| BIT Capital GmbH | -149,380 | -53.8% | 128,131 |
| Sofinnova Investments, Inc. | -88,263 | -25.6% | 255,903 |
| Ensign Peak Advisors, Inc | -80,677 | -14.8% | 466,106 |
| Brevan Howard Capital Management LP | -54,676 | -25.9% | 156,812 |
| SUSQUEHANNA INTERNATIONAL GROUP, LL | -40,502 | -49.7% | 40,954 |