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Also trades as: 0JDI.L (LSE) · $vol 0M

IONS NASDAQ

Ionis Pharmaceuticals, Inc.
1W: -3.2% 1M: -3.5% 3M: -18.6% YTD: -44.8% 1Y: -38.0% 3Y: -4.8% 5Y: +40.5%
$43.96
+0.54 (+1.24%)
 
Weekly Expected Move ±5.4%
$38 $41 $43 $45 $48
NASDAQ · Healthcare · Biotechnology · Tech Score Sell · Power 40 · $7.3B mcap · 163M float · 2.12% daily turnover · Short 39% of daily vol
Credit Risk of going bust: higher than 52% of companies Debt: 24.9% of company value Bonds: $115.2M held by 65 funds → details ▾
Of US companies ranked in the middle of the pack, about 1 in 580 filed for bankruptcy within a year (2020-2025).
If the stock fell to about $1.24 (down 97%), Ionis Pharmaceuticals, Inc. would be worth roughly what it owes.
Total debt $2.42B against a stock market value of $7.31B.
Distance to default 4.96 (Merton model): prices to 2026-10-27, balance sheet 2026-06-30, debt counted $1.20B (short-term plus half of long-term), stock volatility 44.8%; Altman Z'' 1.30. A ranking and a back-test, not a forecast.
Bond figures are fund-reported marks (SEC N-PORT) as of Jul 2026. How these are computed.
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Bullish
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Articles (24h)
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Hourly Sentiment (24h)
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3 bullish 0 neutral 0 bearish
Articles (7d)
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Daily Sentiment (7 Days)
Articles (100)
NVS' Q3 Earnings Top Estimates on Strong Key Drug Sales, Revenues Miss
Bullish Zacks · 11h ago · 0.90
Ionis upgraded at BMO on Tryngolza adoption for severe hypertriglyceridemia
Bullish SeekingAlpha · 6d ago · 0.90
Alnylam Is Now Solidly Profitable. Why Are Investors Treating It Like a Broken Biotech?
Bullish MotleyFool · 6d ago · 0.90
Novartis halts mid-stage trial for kidney drug, Fabhalta, in lupus nephritis
Bearish SeekingAlpha · 1w ago · -0.90
Lilly, Pfizer, J&J among winners of EU drug recommendations this month
Bullish SeekingAlpha · 1w ago · 0.90
FDA unveils rare disease initiative to enhance therapy development
Bullish SeekingAlpha · 1w ago · 0.90
Alnylam vs. Ionis: Here's the Better Bad-News Buy
Bullish MotleyFool · 2w ago · 0.90
Novartis Strengthens RNA Therapeutics Pipeline With $7.8B Abogen Deal
Bullish Zacks · 3w ago · 0.90
These ten healthcare stocks posted the biggest one-month losses
Bearish SeekingAlpha · 3w ago · -0.90
4 RNA Therapeutics Stocks Leading the Next Wave of Innovation
Bullish Zacks · 4w ago · 0.90
Cathie Wood's Ark Invest weekly recap: boosts Meta, Rocket Lab; cuts Tempus AI, CrowdStrike
SeekingAlpha · 4w ago · 0.00
18 of 21 Analysts Still Think Alnylam Stock Is a Buy. Here's Why They're Right.
Bullish MotleyFool · 4w ago · 0.90
NewEdge Advisors LLC Sells 16,964 Shares of Ionis Pharmaceuticals, Inc. $IONS
Bearish DefenseWorld · 4w ago · -0.90
Ionis Delivers Positive Late-Stage Results for Two Partnered Drugs
Bullish Zacks · 4w ago · 0.90
Roche, Ionis succeed in late-stage trial for kidney disease therapy
Bullish SeekingAlpha · 4w ago · 0.90
Ionis gains on late-stage trial results for ulefnersen in ALS
Bullish SeekingAlpha · 5w ago · 0.90
NVS Gets Positive CHMP Opinion for Cosentyx for Another Indication
Bullish Zacks · 5w ago · 0.90
Cathie Wood's weekly recap: buys $25M of CoreWeave, trims $40M in Bitcoin ETF
SeekingAlpha · 5w ago · 0.00
Investors Dumped Ionis Pharmaceuticals Stock -- But Wall Street Hasn't Budged From Its Bullish Outlook
Bearish MotleyFool · 5w ago · -0.90
Bank of America Corp DE Makes New Investment in Ionis Pharmaceuticals, Inc. $IONS
Bullish DefenseWorld · 5w ago · 0.90
10 mid-cap U.S. healthcare stocks with the weakest momentum grades
Bearish SeekingAlpha · 5w ago · -0.90
Can AstraZeneca's Broad Pipeline Offset Recent Setbacks?
Bullish Zacks · 5w ago · 0.90
Amneal (AMRX) Surges 8.6%: Is This an Indication of Further Gains?
Zacks · 5w ago · 0.00
Novartis scraps ALS therapy after mid-stage trial setback
Bearish SeekingAlpha · 5w ago · -0.90
PHVS Stock Rises 10% in a Month: What Is Driving the Rally?
Bullish Zacks · 6w ago · 0.90
Novartis Just Shook Up a Multibillion-Dollar Drug Race. What It Means for Eli Lilly Stock.
MotleyFool · 6w ago · 0.00
California State Teachers Retirement System Boosts Holdings in Ionis Pharmaceuticals, Inc. $IONS
Bullish DefenseWorld · 6w ago · 0.90
Chip stocks lead Nasdaq's weekly gains; Amgen plunges after trial setback
SeekingAlpha · 6w ago · 0.00
Novartis facing board change threat from shareholder following trial failures
Bearish SeekingAlpha · 6w ago · -0.90
Cathie Wood Is Loading Up on Ionis Pharmaceuticals (IONS) Stock. Here's the Bet She's Making.
Bullish MotleyFool · 6w ago · 0.90
Novartis' Del-desiran Fails Late-Stage DM1 Study, Shares Fall
Bearish Zacks · 6w ago · -0.90
Novartis extends selloff as Deutsche Bank cuts on twin drug trial setbacks
Bearish SeekingAlpha · 6w ago · -0.90
Theravance Bio (TBPH) Up 0.8% Since Last Earnings Report: Can It Continue?
Bullish Zacks · 6w ago · 0.90
Amgen drops on Novartis trial setback for heart therapy; BMO downgrades
Bearish SeekingAlpha · 7w ago · -0.90
At a glance: stocks gapping down premarket
Bearish SeekingAlpha · 7w ago · -0.90
Novartis Late-Stage Cardiovascular Outcome Study Fails, Stock Down
Bearish Zacks · 7w ago · -0.90
Amgen Shares Fall as Novartis' Pelacarsen Misses Phase III Study Goal
Bearish Zacks · 7w ago · -0.90
Ionis Pharmaceuticals falls after Pelacarsen fails key Phase 3 heart trial
Bearish SeekingAlpha · 7w ago · -0.90
IONS Secures FDA Nod for Rare Brain Disorder Drug Zanvastro
Bullish Zacks · 7w ago · 0.90
Ionis gains approval of zilganersen for Alexander disease
Bullish SeekingAlpha · 7w ago · 0.90
Here's Why Ionis Pharmaceuticals' Steep Sell-off Was Overdone
Bullish MotleyFool · 7w ago · 0.90
Indivior Pharmaceuticals Inc. (INDV) Down 5.3% Since Last Earnings Report: Can It Rebound?
Bearish Zacks · 7w ago · -0.90
Why Is Ionis Pharmaceuticals (IONS) Up 17.2% Since Last Earnings Report?
Bullish Zacks · 8w ago · 0.90
Bank of New York Mellon Corp Takes $43.01 Million Position in Ionis Pharmaceuticals, Inc. $IONS
Bullish DefenseWorld · 8w ago · 0.90
ADAR1 Capital Management LLC Acquires Shares of 166,286 Ionis Pharmaceuticals, Inc. $IONS
Bullish DefenseWorld · 8w ago · 0.90
ADAR1 Capital Management LLC Acquires Shares of 166,286 Ionis Pharmaceuticals, Inc. $IONS
Bullish DefenseWorld · 8w ago · 0.90
Breakfast News: A Conversation With Ionis CEO
Bullish MotleyFool · 9w ago · 0.90
Why the Alnylam Sell-Off Looks Overdone -- and What Investors Are Missing
Bullish MotleyFool · 10w ago · 0.90
Ionis Stock Has Plunged 30%. Is It Time to Buy the Beaten-Down Stock?
Bearish MotleyFool · 10w ago · -0.90
Ionis (IONS) Q2 2026 Earnings Call Transcript
Bullish MotleyFool · 11w ago · 0.90
Ionis Pharmaceuticals Director Hayden Buys $1.1 Million Shares. What Does This Mean for Investors?
Bullish MotleyFool · 12w ago · 0.90
IONS Beats Q2 Earnings & Sales Estimates, Reiterates '26 Outlook
Bullish Zacks · 12w ago · 0.90
Biogen's Q2 Earnings Beat, New Drugs Drive Sales, 2026 Guidance Raised
Bullish Zacks · 12w ago · 0.90
Ionis Pharmaceuticals (IONS) Reports Q2 Loss, Tops Revenue Estimates
Bullish Zacks · 12w ago · 0.90
Ionis Pharmaceuticals GAAP EPS of -$0.69 beats by $0.38, revenue of $268M beats by $77.91M
Bullish SeekingAlpha · 12w ago · 0.90
Here are the major earnings before the open Wednesday
SeekingAlpha · 13w ago · 0.00
Entropy Technologies LP Makes New $2.04 Million Investment in Ionis Pharmaceuticals, Inc. $IONS
Bullish DefenseWorld · 13w ago · 0.90
Neurocrine Biosciences (NBIX) Earnings Expected to Grow: What to Know Ahead of Next Week's Release
Bullish Zacks · 13w ago · 0.90
Earnings Preview: Ionis Pharmaceuticals (IONS) Q2 Earnings Expected to Decline
Bearish Zacks · 13w ago · -0.90
Amova Asset Management Americas Inc. Has $6.13 Million Stock Position in Ionis Pharmaceuticals, Inc. $IONS
Bearish DefenseWorld · 14w ago · -0.90
Cathie Wood Just Bet Big on This Biotech Stock
Bullish MotleyFool · 14w ago · 0.90
Biogen Shares Decline After Detailed Diranersen Alzheimer's Study Data
Bearish Zacks · 14w ago · -0.90
Biogen Wins FDA Approval for Subcutaneous Starter Dose of Leqembi
Bullish Zacks · 15w ago · 0.90
Ionis Begins Dosing in Phase I/II Dravet Syndrome Study
Bullish Zacks · 15w ago · 0.90
Reasons Why Investors Should Consider Betting on PTC Stock Now
Bullish Zacks · 15w ago · 0.90
Ionis extends losses as Roche scraps two partnered studies
Bearish SeekingAlpha · 15w ago · -0.90
AstraZeneca's Stock Drops on Wainua's Setback in ATTR-CM Study
Bearish Zacks · 15w ago · -0.90
AstraZeneca tumbles as heart drug trial misses main efficacy goal
Bearish SeekingAlpha · 15w ago · -0.90
IONS Completes Enrollment in Pivotal Cohort of Angelman Syndrome Study
Bullish Zacks · 16w ago · 0.90
Citi's picks and pans for H2 '26: REITs, tech, consumer, health
SeekingAlpha · 16w ago · 0.00
IONS Out-Licenses ex-U.S. Rights for Rare Neurology Drug to Recordati
Bullish Zacks · 17w ago · 0.90
FDA Expands IONS' Tryngolza Label to Treat Severe Hypertriglyceridemia
Bullish Zacks · 17w ago · 0.90
Ionis, Recordati inks ex-U.S. license deal for Zilganerse
Bullish SeekingAlpha · 17w ago · 0.90
Intellia's One-Time Gene Editing Therapy Gains Ground Against Rivals In Rare Swelling Disorder
Bullish Benzinga-Movers · 19w ago · 0.90
BIIB's Next-Gen SMA Therapy Salanersen Wins FDA's Breakthrough Tag
Bullish Zacks · 20w ago · 0.90
Why Is Ionis Pharmaceuticals (IONS) Up 3.4% Since Last Earnings Report?
Bullish Zacks · 21w ago · 0.90
BIIB Advances Alzheimer's Disease Drug Despite Study Missing Main Goal
Zacks · 23w ago · 0.00
Why Is Biogen Stock Falling Thursday?
Bearish Benzinga-Movers · 23w ago · -0.90
GSK Targets China's Hepatitis B Market Through New Deal
Bullish Benzinga-Biotech · 24w ago · 0.90
IONS Q1 Earnings & Sales Beat, Stock Rises on Raised '26 View
Bullish Zacks · 25w ago · 0.90
Ionis outlines 2026 revenue of $875M-$900M while lifting olezarsen peak sales view to >$3B
Bullish SeekingAlpha · 25w ago · 0.90
Ionis (IONS) Q1 2026 Earnings Call Transcript
MotleyFool · 25w ago · 0.00
GSK Q1 Earnings Beat Estimates, Specialty Medicines Drive Sales Growth
Bullish Zacks · 25w ago · 0.90
Compared to Estimates, Ionis Pharmaceuticals (IONS) Q1 Earnings: A Look at Key Metrics
Zacks · 25w ago · 0.00
Ionis Pharmaceuticals (IONS) Reports Q1 Loss, Tops Revenue Estimates
Bullish Zacks · 25w ago · 0.90
Earnings Scheduled For April 29, 2026
Benzinga-Earnings · 25w ago · 0.00
Ionis Pharmaceuticals beats top-line and bottom-line estimates; introduces FY26 outlook
Bullish SeekingAlpha · 25w ago · 0.90
Ionis Pharmaceuticals Q1 2026 Earnings Preview
SeekingAlpha · 26w ago · 0.00
Ionis Pharmaceuticals, Inc. $IONS Shares Bought by Assetmark Inc.
Bullish DefenseWorld · 26w ago · 0.90
Ionis (IONS) Q4 2025 Earnings Transcript
MotleyFool · 27w ago · 0.00
Ionis Pharmaceuticals, Inc. $IONS Shares Sold by Aberdeen Group plc
DefenseWorld · 28w ago · 0.00
Ionis Pharmaceuticals, Inc. $IONS Shares Acquired by SG Americas Securities LLC
Bullish DefenseWorld · 29w ago · 0.90
Biogen Secures FDA Nod for Higher Dose of SMA Drug Spinraza
Bullish Zacks · 30w ago · 0.90
Cathie Wood's Ark Invest in broad sell-off; trims AI, crypto, internet names
Bearish SeekingAlpha · 30w ago · -0.90
Assenagon Asset Management S.A. Cuts Stake in Ionis Pharmaceuticals, Inc. $IONS
Bearish DefenseWorld · 30w ago · -0.90
Why Is Ionis Pharmaceuticals (IONS) Down 7.9% Since Last Earnings Report?
Bearish Zacks · 30w ago · -0.90
Ionis Pharmaceuticals Repriced Drug Ahead Of Key FDA Decision Signals Push Into Larger Market
Bearish Benzinga-News · 30w ago · -0.90
DAVENPORT & Co LLC Purchases 155,334 Shares of Ionis Pharmaceuticals, Inc. $IONS
Bullish DefenseWorld · 30w ago · 0.90
FDA Grants Priority Tag to Ionis' NDA for Alexander Disease Drug
Bullish Zacks · 31w ago · 0.90
When Insider Selling Is a Good Thing: 2 Stocks to Watch
Bearish MarketBeat · 31w ago · -0.90

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