— Know what they know.
Not Investment Advice
Also trades as: 0JDI.L (LSE) · $vol 0M

IONS Short Interest

Ionis Pharmaceuticals, Inc.
1W: -3.2% 1M: -3.5% 3M: -18.6% YTD: -44.8% 1Y: -38.0% 3Y: -4.8% 5Y: +40.5%
$43.96
+0.54 (+1.24%)
Pre-Market: $43.65 (-0.31, -0.71%)
Weekly Expected Move ±5.4%
$38 $41 $43 $45 $48
NASDAQ · Healthcare · Biotechnology · Tech Score Sell · Power 40 · $7.3B mcap · 163M float · 2.12% daily turnover · Short 39% of daily vol
Credit Risk of going bust: higher than 52% of companies Debt: 24.9% of company value Bonds: $115.2M held by 65 funds → details ▾
Of US companies ranked in the middle of the pack, about 1 in 580 filed for bankruptcy within a year (2020-2025).
If the stock fell to about $1.24 (down 97%), Ionis Pharmaceuticals, Inc. would be worth roughly what it owes.
Total debt $2.42B against a stock market value of $7.31B.
Distance to default 4.96 (Merton model): prices to 2026-10-27, balance sheet 2026-06-30, debt counted $1.20B (short-term plus half of long-term), stock volatility 44.8%; Altman Z'' 1.30. A ranking and a back-test, not a forecast.
Bond figures are fund-reported marks (SEC N-PORT) as of Jul 2026. How these are computed.

Short Volume Summary

2026-10-26
29.2%
Short Ratio
of total volume
36.7%
20-Day Avg
39.0%
50-Day Avg
▼ Falling
5-Day Trend
0.2M
Short Volume
0.7M
Total Volume

Daily Short Volume Ratio

Short Volume vs Total Volume

Exchange Breakdown

2026-10-26
ExchangeShort VolumeTotal VolumeShort %
NASDAQ 199,831 714,263 28.0%
NYSE 18,507 34,045 54.4%
BATS 155 633 24.5%

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For informational purposes only. Not investment advice. Data sourced from SEC filings. Privacy Terms