SEPN Institutional Ownership
Septerna Inc
1W: -0.2%
1M: +0.6%
3M: +12.7%
YTD: +34.8%
1Y: +98.5%
$37.71
-0.34 (-0.89%)
Weekly Expected Move ±5.6%
$34
$36
$38
$40
$42
Overview
News
Chart
Smart Money
Financials
Income Statement
Cash Flow
Balance Sheet
Earnings
Dividends
Analysis
Technicals
Weather
Peers
ESG
Institutions
ETF Exposure
Dark Pool
Short Interest
Supply Chain
Institutional Ownership — SEPN
174
Institutional Holders
+25 vs prior quarter
0.0%
Ownership
+0.00pp
$2B
Total Invested
50
New Positions
49
Increased
48
Reduced
16
Closed
1.00
Put/Call Ratio
Ownership Trends
Top Institutional Holders (189 total)
| # | Holder | Shares | Value | Change | Change % | Holding Period | Filing |
|---|---|---|---|---|---|---|---|
| 1 | RA CAPITAL MANAGEMENT, L.P. | 6,995,858 | $$264M | — | +0.0% | 7Q | SEC ↗ |
| 2 | TRV GP V, LLC | 6,215,591 | $$234M | — | +0.0% | 7Q | SEC ↗ |
| 3 | Driehaus Capital Management LLC | 4,433,058 | $$167M | +37,486 | +0.9% | 7Q | SEC ↗ |
| 4 | TRV GP VI, LLC | 4,211,659 | $$159M | — | +0.0% | 7Q | SEC ↗ |
| 5 | SAMSARA BIOCAPITAL, LLC | 3,149,128 | $$119M | — | +0.0% | 7Q | SEC ↗ |
| 6 | GOLDMAN SACHS GROUP INC | 3,062,766 | $$115M | +156,339 | +5.4% | 7Q | SEC ↗ |
| 7 | BlackRock, Inc. | 1,932,088 | $$73M | +109,914 | +6.0% | 7Q | SEC ↗ |
| 8 | Siren, L.L.C. | 1,900,000 | $$72M | -100,000 | -5.0% | 7Q | SEC ↗ |
| 9 | Avoro Capital Advisors LLC | 1,337,500 | $$50M | — | +0.0% | 7Q | SEC ↗ |
| 10 | Jupiter Topco LLC NEW | 1,307,500 | $$49M | — | +0.0% | 1Q | SEC ↗ |
| 11 | VANGUARD CAPITAL MANAGEMENT LLC | 1,221,673 | $$46M | +24,711 | +2.1% | 2Q | SEC ↗ |
| 12 | PRIMECAP MANAGEMENT CO/CA | 1,167,382 | $$44M | +118,548 | +11.3% | 3Q | SEC ↗ |
| 13 | First Light Asset Management, LLC | 963,260 | $$36M | +230,400 | +31.4% | 3Q | SEC ↗ |
| 14 | ADAR1 Capital Management, LLC | 940,747 | $$35M | -149,071 | -13.7% | 6Q | SEC ↗ |
| 15 | JANUS HENDERSON GROUP PLC NEW | 890,754 | $$34M | — | +0.0% | 1Q | SEC ↗ |
| 16 | GEODE CAPITAL MANAGEMENT, LLC | 679,163 | $$26M | +34,017 | +5.3% | 7Q | SEC ↗ |
| 17 | STATE STREET CORP | 652,630 | $$25M | +21,183 | +3.4% | 7Q | SEC ↗ |
| 18 | LOOMIS SAYLES & CO L P NEW | 624,752 | $$24M | — | +0.0% | 1Q | SEC ↗ |
| 19 | Casdin Capital, LLC | 553,268 | $$21M | — | +0.0% | 7Q | SEC ↗ |
| 20 | Catalio Capital Management, LP | 536,152 | $$20M | +241,792 | +82.1% | 7Q | SEC ↗ |
| 21 | ALGERT GLOBAL LLC | 397,487 | $$15M | +376,452 | +1789.6% | 3Q | SEC ↗ |
| 22 | Balyasny Asset Management L.P. | 350,442 | $$13M | +113,763 | +48.1% | 3Q | SEC ↗ |
| 23 | Longaeva Partners L.P. | 298,171 | $$11M | +223,604 | +299.9% | 4Q | SEC ↗ |
| 24 | Soleus Capital Management, L.P. | 275,000 | $$10M | — | +0.0% | 7Q | SEC ↗ |
| 25 | VANGUARD PORTFOLIO MANAGEMENT LLC | 230,184 | $$9M | +35,141 | +18.0% | 2Q | SEC ↗ |
| 26 | Universal- Beteiligungs- und Servicege | 222,702 | $$8M | -1,293 | -0.6% | 7Q | SEC ↗ |
| 27 | TWO SIGMA INVESTMENTS, LP | 220,885 | $$8M | +145,518 | +193.1% | 6Q | SEC ↗ |
| 28 | NORTHERN TRUST CORP | 201,131 | $$8M | +36,601 | +22.2% | 7Q | SEC ↗ |
| 29 | Kalehua Capital Management LLC | 194,544 | $$7M | — | +0.0% | 3Q | SEC ↗ |
| 30 | Sixth Street Partners Management Compa NEW | 187,041 | $$7M | — | +0.0% | 1Q | SEC ↗ |
| 31 | CHARLES SCHWAB INVESTMENT MANAGEMENT I | 187,041 | $$7M | +5,461 | +3.0% | 7Q | SEC ↗ |
| 32 | Woodline Partners LP NEW | 185,535 | $$7M | — | +0.0% | 1Q | SEC ↗ |
| 33 | VANGUARD FIDUCIARY TRUST CO | 165,656 | $$6M | +11,172 | +7.2% | 2Q | SEC ↗ |
| 34 | MORGAN STANLEY | 134,377 | $$5M | +23,847 | +21.6% | 7Q | SEC ↗ |
| 35 | UBS Group AG | 89,874 | $$3M | -27,105 | -23.2% | 7Q | SEC ↗ |
| 36 | FEDERATED HERMES, INC. | 86,753 | $$3M | -2,548 | -2.9% | 3Q | SEC ↗ |
| 37 | JPMORGAN CHASE & CO | 85,301 | $$3M | +627 | +0.7% | 7Q | SEC ↗ |
| 38 | LAZARD ASSET MANAGEMENT LLC NEW | 75,425 | $$3M | — | +0.0% | 1Q | SEC ↗ |
| 39 | DIMENSIONAL FUND ADVISORS LP NEW | 75,309 | $$3M | — | +0.0% | 1Q | SEC ↗ |
| 40 | ARROWSTREET CAPITAL, LIMITED PARTNERSH NEW | 74,649 | $$3M | — | +0.0% | 1Q | SEC ↗ |
| 41 | JACOBS LEVY EQUITY MANAGEMENT, INC | 68,180 | $$3M | +39,744 | +139.8% | 4Q | SEC ↗ |
| 42 | HUSSMAN STRATEGIC ADVISORS, INC. | 63,000 | $$2M | -42,000 | -40.0% | 2Q | SEC ↗ |
| 43 | AMERICAN CENTURY COMPANIES INC | 60,973 | $$2M | -317 | -0.5% | 4Q | SEC ↗ |
| 44 | Bank of New York Mellon Corp | 56,176 | $$2M | -2,533 | -4.3% | 7Q | SEC ↗ |
| 45 | XTX Topco Ltd | 54,489 | $$2M | +17,766 | +48.4% | 3Q | SEC ↗ |
| 46 | MILLENNIUM MANAGEMENT LLC | 50,562 | $$2M | -73,539 | -59.3% | 6Q | SEC ↗ |
| 47 | BARCLAYS PLC | 49,821 | $$2M | +27,107 | +119.3% | 7Q | SEC ↗ |
| 48 | Elmind Capital, LP NEW | 49,444 | $$2M | — | +0.0% | 1Q | SEC ↗ |
| 49 | Nuveen, LLC | 48,229 | $$2M | +19,053 | +65.3% | 6Q | SEC ↗ |
| 50 | Sofinnova Investments, Inc. | 47,506 | $$2M | — | +0.0% | 2Q | SEC ↗ |
Recent Activity
New Positions (20)
| Holder | Shares | Value |
|---|---|---|
| Jupiter Topco LLC | 1,307,500 | $$49M |
| JANUS HENDERSON GROUP PLC | 890,754 | $$34M |
| LOOMIS SAYLES & CO L P | 624,752 | $$24M |
| Sixth Street Partners Management Co | 187,041 | $$7M |
| Woodline Partners LP | 185,535 | $$7M |
| LAZARD ASSET MANAGEMENT LLC | 75,425 | $$3M |
| DIMENSIONAL FUND ADVISORS LP | 75,309 | $$3M |
| ARROWSTREET CAPITAL, LIMITED PARTNE | 74,649 | $$3M |
| Elmind Capital, LP | 49,444 | $$2M |
| D. E. Shaw & Co., Inc. | 46,483 | $$2M |
| JANE STREET GROUP, LLC | 45,552 | $$2M |
| Voleon Capital Management LP | 44,435 | $$2M |
| HRT FINANCIAL LP | 42,022 | $$2M |
| Caption Management, LLC | 38,006 | $$1M |
| Brevan Howard Capital Management LP | 29,452 | $$1M |
| HighVista Strategies LLC | 29,337 | $$1M |
| TUDOR INVESTMENT CORP ET AL | 28,966 | $$1M |
| FOX RUN MANAGEMENT, L.L.C. | 22,038 | $$831K |
| FRED ALGER MANAGEMENT, LLC | 20,958 | $$790K |
| FRANKLIN RESOURCES INC | 18,607 | $$702K |
Sold Out (20)
| Holder | Prev Shares | Prev Value |
|---|---|---|
| BVF INC/IL | 1,353,249 | $$51M |
| Venrock Adviser, LLC | 506,056 | $$19M |
| PERCEPTIVE ADVISORS LLC | 433,160 | $$16M |
| Checkpoint Capital L.P. | 100,300 | $$4M |
| MARSHALL WACE, LLP | 39,840 | $$2M |
| ExodusPoint Capital Management, LP | 37,867 | $$1M |
| Y-Intercept (Hong Kong) Ltd | 25,770 | $$972K |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 24,000 | $$905K |
| VARCOV Co. | 16,752 | $$632K |
| Numerai GP LLC | 15,082 | $$569K |
| AMERIPRISE FINANCIAL INC | 14,090 | $$531K |
| INTECH INVESTMENT MANAGEMENT LLC | 13,283 | $$501K |
| EntryPoint Capital, LLC | 12,776 | $$482K |
| Verition Fund Management LLC | 12,343 | $$465K |
| Seven Fleet Capital Management LP | 11,445 | $$432K |
| Dynamic Technology Lab Private Ltd | 10,810 | $$408K |
| PharVision Advisers, LLC | 10,739 | $$405K |
| Baader Bank Aktiengesellschaft | 10,000 | $$377K |
| Atom Investors LP | 9,791 | $$369K |
| Graham Capital Management, L.P. | 8,971 | $$338K |
Biggest Increases (20)
| Holder | Added | Change % | Total Shares |
|---|---|---|---|
| ALGERT GLOBAL LLC | +376,452 | +1789.6% | 397,487 |
| Catalio Capital Management, LP | +241,792 | +82.1% | 536,152 |
| First Light Asset Management, LLC | +230,400 | +31.4% | 963,260 |
| Longaeva Partners L.P. | +223,604 | +299.9% | 298,171 |
| GOLDMAN SACHS GROUP INC | +156,339 | +5.4% | 3,062,766 |
| TWO SIGMA INVESTMENTS, LP | +145,518 | +193.1% | 220,885 |
| PRIMECAP MANAGEMENT CO/CA | +118,548 | +11.3% | 1,167,382 |
| Balyasny Asset Management L.P. | +113,763 | +48.1% | 350,442 |
| BlackRock, Inc. | +109,914 | +6.0% | 1,932,088 |
| JACOBS LEVY EQUITY MANAGEMENT, INC | +39,744 | +139.8% | 68,180 |
| Driehaus Capital Management LLC | +37,486 | +0.9% | 4,433,058 |
| NORTHERN TRUST CORP | +36,601 | +22.2% | 201,131 |
| VANGUARD PORTFOLIO MANAGEMENT LLC | +35,141 | +18.0% | 230,184 |
| GEODE CAPITAL MANAGEMENT, LLC | +34,017 | +5.3% | 679,163 |
| Russell Investments Group, Ltd. | +28,694 | +249.2% | 40,209 |
| BARCLAYS PLC | +27,107 | +119.3% | 49,821 |
| VANGUARD CAPITAL MANAGEMENT LLC | +24,711 | +2.1% | 1,221,673 |
| MORGAN STANLEY | +23,847 | +21.6% | 134,377 |
| STATE STREET CORP | +21,183 | +3.4% | 652,630 |
| Nuveen, LLC | +19,053 | +65.3% | 48,229 |
Biggest Decreases (20)
| Holder | Reduced | Change % | Total Shares |
|---|---|---|---|
| ADAR1 Capital Management, LLC | -149,071 | -13.7% | 940,747 |
| Siren, L.L.C. | -100,000 | -5.0% | 1,900,000 |
| MILLENNIUM MANAGEMENT LLC | -73,539 | -59.3% | 50,562 |
| Invesco Ltd. | -58,774 | -70.9% | 24,094 |
| HUSSMAN STRATEGIC ADVISORS, INC. | -42,000 | -40.0% | 63,000 |
| Jump Financial, LLC | -32,811 | -61.9% | 20,200 |
| Rangeley Capital, LLC | -32,600 | -81.9% | 7,200 |
| UBS Group AG | -27,105 | -23.2% | 89,874 |
| ACADIAN ASSET MANAGEMENT LLC | -9,982 | -32.2% | 20,996 |
| Trexquant Investment LP | -9,656 | -27.4% | 25,645 |
| FEDERATED HERMES, INC. | -2,548 | -2.9% | 86,753 |
| Bank of New York Mellon Corp | -2,533 | -4.3% | 56,176 |
| Swiss National Bank | -2,300 | -10.4% | 19,800 |
| WINTON GROUP Ltd | -1,660 | -18.8% | 7,182 |
| Virtus Investment Advisers, LLC | -1,617 | -15.1% | 9,102 |
| Universal- Beteiligungs- und Servic | -1,293 | -0.6% | 222,702 |
| China Universal Asset Management Co | -1,172 | -9.8% | 10,774 |
| MetLife Investment Management, LLC | -805 | -5.9% | 12,880 |
| Sterling Capital Management LLC | -512 | -71.9% | 200 |
| MASSACHUSETTS FINANCIAL SERVICES CO | -400 | -3.9% | 9,982 |