GPCR Institutional Ownership
Structure Therapeutics Inc.
1W: -5.8%
1M: -38.5%
3M: -54.5%
YTD: -68.4%
1Y: -18.3%
3Y: -68.1%
$21.55
+0.45 (+2.13%)
Weekly Expected Move ±7.5%
$18
$20
$21
$23
$24
Credit Risk of going bust: lower than 80% of companies Debt: 0.5% of company value Bonds: none of note held by US funds details ▾
Of US companies ranked in the safest four tenths, about 1 in 3,500 filed for bankruptcy within a year (2020-2025).
If the stock fell to about $0.01 (down 99.9%), Structure Therapeutics Inc. would be worth roughly what it owes.
Total debt $6.2M against a stock market value of $1.24B.
Distance to default 9.66 (Merton model): prices to 2026-10-27, balance sheet 2026-06-30, debt counted $3.1M (short-term plus half of long-term), stock volatility 60.7%; Altman Z'' 23.53. A ranking and a back-test, not a forecast.
US fund filings (SEC N-PORT) show under $25M of this company's bonds, so there is no bond page. Its debt may be bank loans or privately placed. How these are computed.
If the stock fell to about $0.01 (down 99.9%), Structure Therapeutics Inc. would be worth roughly what it owes.
Total debt $6.2M against a stock market value of $1.24B.
Distance to default 9.66 (Merton model): prices to 2026-10-27, balance sheet 2026-06-30, debt counted $3.1M (short-term plus half of long-term), stock volatility 60.7%; Altman Z'' 23.53. A ranking and a back-test, not a forecast.
US fund filings (SEC N-PORT) show under $25M of this company's bonds, so there is no bond page. Its debt may be bank loans or privately placed. How these are computed.
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Institutional Ownership — GPCR
225
Institutional Holders
-9 vs prior quarter
0.0%
Ownership
+0.00pp
$4B
Total Invested
30
New Positions
75
Increased
81
Reduced
30
Closed
0.88
Put/Call Ratio
Ownership Trends
Top Institutional Holders (255 total)
| # | Holder | Shares | Value | Change | Change % | Holding Period | Filing |
|---|---|---|---|---|---|---|---|
| 1 | FMR LLC | 7,810,306 | $168M | -593,143 | -7.1% | 14Q | SEC ↗ |
| 2 | WELLINGTON MANAGEMENT GROUP LLP | 7,379,433 | $159M | +119,146 | +1.6% | 14Q | SEC ↗ |
| 3 | Avoro Capital Advisors LLC | 6,555,555 | $141M | — | +0.0% | 4Q | SEC ↗ |
| 4 | JANUS HENDERSON GROUP PLC | 5,354,981 | $115M | +264,833 | +5.2% | 13Q | SEC ↗ |
| 5 | Jupiter Topco LLC NEW | 5,204,212 | $112M | — | +0.0% | 1Q | SEC ↗ |
| 6 | Deep Track Capital, LP | 4,740,072 | $102M | +460,224 | +10.8% | 14Q | SEC ↗ |
| 7 | BVF INC/IL | 3,366,823 | $73M | -92,535 | -2.7% | 14Q | SEC ↗ |
| 8 | MORGAN STANLEY | 2,806,640 | $60M | +501,183 | +21.7% | 12Q | SEC ↗ |
| 9 | ORBIMED ADVISORS LLC | 2,209,400 | $48M | +733,997 | +49.7% | 9Q | SEC ↗ |
| 10 | PRINCIPAL FINANCIAL GROUP INC | 1,752,753 | $38M | -1,011 | -0.1% | 9Q | SEC ↗ |
| 11 | AMERICAN CENTURY COMPANIES INC | 1,682,179 | $36M | +244,148 | +17.0% | 10Q | SEC ↗ |
| 12 | RTW INVESTMENTS, LP NEW | 1,607,507 | $35M | — | +0.0% | 1Q | SEC ↗ |
| 13 | Driehaus Capital Management LLC | 1,553,219 | $33M | -24,137 | -1.5% | 14Q | SEC ↗ |
| 14 | BAKER BROS. ADVISORS LP | 1,432,529 | $31M | — | +0.0% | 8Q | SEC ↗ |
| 15 | Casdin Capital, LLC | 1,175,000 | $25M | — | +0.0% | 14Q | SEC ↗ |
| 16 | DEERFIELD MANAGEMENT COMPANY, L.P. | 1,086,000 | $23M | +318,007 | +41.4% | 14Q | SEC ↗ |
| 17 | CAPITOLIS LIQUID GLOBAL MARKETS LLC | 1,041,100 | $22M | -110,200 | -9.6% | 2Q | SEC ↗ |
| 18 | Siren, L.L.C. | 872,967 | $19M | -455,731 | -34.3% | 4Q | SEC ↗ |
| 19 | PRICE T ROWE ASSOCIATES INC /MD | 845,532 | $18M | -1,155,164 | -57.7% | 14Q | SEC ↗ |
| 20 | Pacific Heights Asset Management LLC | 800,000 | $17M | +50,000 | +6.7% | 5Q | SEC ↗ |
| 21 | Rock Springs Capital Management LP | 640,317 | $14M | +100 | +0.0% | 11Q | SEC ↗ |
| 22 | Aberdeen Group plc | 639,915 | $14M | +248,106 | +63.3% | 9Q | SEC ↗ |
| 23 | ALLIANCEBERNSTEIN L.P. | 611,708 | $13M | -27,105 | -4.2% | 5Q | SEC ↗ |
| 24 | FRANKLIN RESOURCES INC | 578,839 | $12M | +47,244 | +8.9% | 14Q | SEC ↗ |
| 25 | BANK OF AMERICA CORP /DE | 563,422 | $12M | +336,290 | +148.1% | 13Q | SEC ↗ |
| 26 | BlackRock, Inc. | 511,149 | $11M | +69,174 | +15.7% | 8Q | SEC ↗ |
| 27 | Logos Global Management LP | 500,000 | $11M | — | +0.0% | 14Q | SEC ↗ |
| 28 | Parkman Healthcare Partners LLC | 485,661 | $10M | +253,568 | +109.3% | 3Q | SEC ↗ |
| 29 | Davern Capital Partners, LP | 446,059 | $10M | +319,598 | +252.7% | 2Q | SEC ↗ |
| 30 | HEALTHCARE OF ONTARIO PENSION PLAN TRU | 418,800 | $9M | -49,000 | -10.5% | 3Q | SEC ↗ |
| 31 | UBS Group AG | 378,986 | $8M | +166,067 | +78.0% | 11Q | SEC ↗ |
| 32 | DEUTSCHE BANK AG | 331,867 | $7M | — | +0.0% | 3Q | SEC ↗ |
| 33 | NEXTBio Capital Management LP | 312,496 | $7M | +179,257 | +134.5% | 3Q | SEC ↗ |
| 34 | Catalio Capital Management, LP | 276,550 | $6M | +21,171 | +8.3% | 7Q | SEC ↗ |
| 35 | MARSHALL WACE, LLP | 267,592 | $6M | +198,485 | +287.2% | 3Q | SEC ↗ |
| 36 | HSG Holding Ltd | 266,062 | $6M | — | +0.0% | 12Q | SEC ↗ |
| 37 | SEB Asset Management AB | 245,043 | $5M | — | +0.0% | 2Q | SEC ↗ |
| 38 | GOLDMAN SACHS GROUP INC | 242,790 | $5M | -17,753 | -6.8% | 12Q | SEC ↗ |
| 39 | AMERIPRISE FINANCIAL INC | 230,514 | $5M | +10,998 | +5.0% | 11Q | SEC ↗ |
| 40 | NATIONAL BANK OF CANADA /FI | 215,800 | $5M | -89,600 | -29.3% | 8Q | SEC ↗ |
| 41 | TWO SIGMA INVESTMENTS, LP | 204,156 | $4M | +22,741 | +12.5% | 4Q | SEC ↗ |
| 42 | Eversept Partners, LP | 196,302 | $4M | +58,266 | +42.2% | 5Q | SEC ↗ |
| 43 | Schonfeld Strategic Advisors LLC | 190,685 | $4M | +25,259 | +15.3% | 3Q | SEC ↗ |
| 44 | Woodline Partners LP | 153,808 | $3M | -37,000 | -19.4% | 14Q | SEC ↗ |
| 45 | NOMURA ASSET MANAGEMENT INTERNATIONAL | 153,119 | $3M | +19,104 | +14.3% | 3Q | SEC ↗ |
| 46 | ArrowMark Colorado Holdings LLC | 150,579 | $3M | -37,616 | -20.0% | 14Q | SEC ↗ |
| 47 | Susquehanna Portfolio Strategies, LLC | 148,948 | $3M | +88,431 | +146.1% | 5Q | SEC ↗ |
| 48 | CenterBook Partners LP | 148,030 | $3M | +126,793 | +597.0% | 2Q | SEC ↗ |
| 49 | Rhenman & Partners Asset Management AB | 145,100 | $3M | +17,000 | +13.3% | 6Q | SEC ↗ |
| 50 | B Group, Inc. | 140,000 | $3M | +12,500 | +9.8% | 3Q | SEC ↗ |
Recent Activity
New Positions (20)
| Holder | Shares | Value |
|---|---|---|
| Jupiter Topco LLC | 5,204,212 | $112M |
| RTW INVESTMENTS, LP | 1,607,507 | $35M |
| ExodusPoint Capital Management, LP | 78,266 | $2M |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 75,000 | $2M |
| Y-Intercept (Hong Kong) Ltd | 27,573 | $594K |
| NOMURA HOLDINGS INC | 22,873 | $493K |
| Handelsbanken Fonder AB | 19,400 | $418K |
| ADAR1 Capital Management, LLC | 17,500 | $377K |
| Gladstone Institutional Advisory LL | 13,275 | $286K |
| Fulcrum Asset Management LLP | 13,252 | $286K |
| FOX RUN MANAGEMENT, L.L.C. | 10,776 | $232K |
| IMC-Chicago, LLC | 8,618 | $186K |
| SIMPLEX TRADING, LLC | 7,871 | $170K |
| Clearstead Advisors, LLC | 7,826 | $169K |
| EntryPoint Capital, LLC | 6,136 | $132K |
| NORTHERN TRUST CORP | 5,080 | $109K |
| Walleye Trading LLC | 4,113 | $89K |
| Prospera Financial Services Inc | 4,100 | $88K |
| GABELLI FUNDS LLC | 4,050 | $87K |
| NATIXIS | 2,482 | $53K |
Sold Out (20)
| Holder | Prev Shares | Prev Value |
|---|---|---|
| Paradigm Biocapital Advisors LP | 545,287 | $12M |
| FARALLON CAPITAL MANAGEMENT LLC | 454,000 | $10M |
| EcoR1 Capital, LLC | 334,380 | $7M |
| Balyasny Asset Management L.P. | 304,934 | $7M |
| Capricorn Fund Managers Ltd | 252,600 | $5M |
| Pentwater Capital Management LP | 245,000 | $5M |
| Sio Capital Management, LLC | 209,093 | $5M |
| Holocene Advisors, LP | 159,009 | $3M |
| TCG Crossover Management, LLC | 140,411 | $3M |
| Alyeska Investment Group, L.P. | 115,000 | $2M |
| Trexquant Investment LP | 107,884 | $2M |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS | 99,617 | $2M |
| SummitTX Capital, L.P. | 94,671 | $2M |
| DIADEMA PARTNERS LP | 72,234 | $2M |
| Longaeva Partners L.P. | 60,000 | $1M |
| RENAISSANCE TECHNOLOGIES LLC | 55,800 | $1M |
| Monashee Investment Management LLC | 50,000 | $1M |
| Integral Health Asset Management, L | 50,000 | $1M |
| Pier Capital, LLC | 47,551 | $1M |
| ACT CAPITAL MANAGEMENT, LLC | 38,500 | $830K |
Biggest Increases (20)
| Holder | Added | Change % | Total Shares |
|---|---|---|---|
| ORBIMED ADVISORS LLC | +733,997 | +49.7% | 2,209,400 |
| MORGAN STANLEY | +501,183 | +21.7% | 2,806,640 |
| Deep Track Capital, LP | +460,224 | +10.8% | 4,740,072 |
| BANK OF AMERICA CORP /DE | +336,290 | +148.1% | 563,422 |
| Davern Capital Partners, LP | +319,598 | +252.7% | 446,059 |
| DEERFIELD MANAGEMENT COMPANY, L.P. | +318,007 | +41.4% | 1,086,000 |
| JANUS HENDERSON GROUP PLC | +264,833 | +5.2% | 5,354,981 |
| Parkman Healthcare Partners LLC | +253,568 | +109.3% | 485,661 |
| Aberdeen Group plc | +248,106 | +63.3% | 639,915 |
| AMERICAN CENTURY COMPANIES INC | +244,148 | +17.0% | 1,682,179 |
| MARSHALL WACE, LLP | +198,485 | +287.2% | 267,592 |
| NEXTBio Capital Management LP | +179,257 | +134.5% | 312,496 |
| UBS Group AG | +166,067 | +78.0% | 378,986 |
| CenterBook Partners LP | +126,793 | +597.0% | 148,030 |
| WELLINGTON MANAGEMENT GROUP LLP | +119,146 | +1.6% | 7,379,433 |
| Squarepoint Ops LLC | +102,929 | +454.5% | 125,575 |
| Susquehanna Portfolio Strategies, L | +88,431 | +146.1% | 148,948 |
| BlackRock, Inc. | +69,174 | +15.7% | 511,149 |
| Avidity Partners Management LP | +68,000 | +226.7% | 98,000 |
| SUSQUEHANNA INTERNATIONAL GROUP, LL | +66,502 | +119.1% | 122,344 |
Biggest Decreases (20)
| Holder | Reduced | Change % | Total Shares |
|---|---|---|---|
| PRICE T ROWE ASSOCIATES INC /MD | -1,155,164 | -57.7% | 845,532 |
| FMR LLC | -593,143 | -7.1% | 7,810,306 |
| Siren, L.L.C. | -455,731 | -34.3% | 872,967 |
| JPMORGAN CHASE & CO | -208,819 | -98.1% | 3,984 |
| STEMPOINT CAPITAL LP | -162,089 | -80.9% | 38,178 |
| VOLORIDGE INVESTMENT MANAGEMENT, LL | -142,669 | -56.0% | 112,300 |
| TD Asset Management Inc | -135,800 | -66.3% | 68,962 |
| CAPITOLIS LIQUID GLOBAL MARKETS LLC | -110,200 | -9.6% | 1,041,100 |
| Cormorant Asset Management, LP | -100,000 | -57.1% | 75,000 |
| BVF INC/IL | -92,535 | -2.7% | 3,366,823 |
| NATIONAL BANK OF CANADA /FI | -89,600 | -29.3% | 215,800 |
| D. E. Shaw & Co., Inc. | -89,490 | -43.7% | 115,300 |
| MILLENNIUM MANAGEMENT LLC | -79,363 | -47.0% | 89,568 |
| MANUFACTURERS LIFE INSURANCE COMPAN | -76,706 | -66.8% | 38,108 |
| Birchview Capital, LP | -76,000 | -76.0% | 24,000 |
| Jump Financial, LLC | -65,199 | -60.4% | 42,658 |
| Jones Hill Capital LP | -60,026 | -59.7% | 40,567 |
| HEALTHCARE OF ONTARIO PENSION PLAN | -49,000 | -10.5% | 418,800 |
| ArrowMark Colorado Holdings LLC | -37,616 | -20.0% | 150,579 |
| Woodline Partners LP | -37,000 | -19.4% | 153,808 |