PRLD Institutional Ownership
Prelude Therapeutics Incorporated
1W: -5.4%
1M: -32.4%
3M: -26.4%
YTD: +34.4%
1Y: +143.1%
3Y: +19.5%
5Y: -89.4%
$3.67
-0.12 (-3.17%)
Weekly Expected Move ±9.4%
$3
$3
$4
$4
$4
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Institutional Ownership — PRLD
90
Institutional Holders
+31 vs prior quarter
0.0%
Ownership
+0.00pp
$261M
Total Invested
36
New Positions
25
Increased
21
Reduced
13
Closed
1.00
Put/Call Ratio
Ownership Trends
Top Institutional Holders (94 total)
| # | Holder | Shares | Value | Change | Change % | Holding Period | Filing |
|---|---|---|---|---|---|---|---|
| 1 | ORBIMED ADVISORS LLC | 13,724,571 | $$50M | +2,815,315 | +25.8% | 24Q | SEC ↗ |
| 2 | BAKER BROS. ADVISORS LP | 10,123,824 | $$37M | — | +0.0% | 24Q | SEC ↗ |
| 3 | RA CAPITAL MANAGEMENT, L.P. NEW | 6,475,882 | $$24M | — | +0.0% | 1Q | SEC ↗ |
| 4 | Soleus Capital Management, L.P. NEW | 3,378,378 | $$12M | — | +0.0% | 1Q | SEC ↗ |
| 5 | Kynam Capital Management, LP | 2,415,087 | $$9M | +822,536 | +51.6% | 3Q | SEC ↗ |
| 6 | VANGUARD CAPITAL MANAGEMENT LLC | 2,009,445 | $$7M | +779,039 | +63.3% | 2Q | SEC ↗ |
| 7 | BlackRock, Inc. | 1,797,501 | $$7M | +1,475,615 | +458.4% | 8Q | SEC ↗ |
| 8 | SPHERA FUNDS MANAGEMENT LTD. | 1,019,832 | $$4M | +461,493 | +82.7% | 3Q | SEC ↗ |
| 9 | TWO SIGMA INVESTMENTS, LP | 993,369 | $$4M | +69,743 | +7.6% | 19Q | SEC ↗ |
| 10 | ADAR1 Capital Management, LLC | 900,900 | $$3M | +748,075 | +489.5% | 2Q | SEC ↗ |
| 11 | MILLENNIUM MANAGEMENT LLC | 844,993 | $$3M | +462,256 | +120.8% | 8Q | SEC ↗ |
| 12 | GEODE CAPITAL MANAGEMENT, LLC | 841,862 | $$3M | +539,404 | +178.3% | 23Q | SEC ↗ |
| 13 | ADAGE CAPITAL PARTNERS GP, L.L.C. NEW | 766,095 | $$3M | — | +0.0% | 1Q | SEC ↗ |
| 14 | ACADIAN ASSET MANAGEMENT LLC | 611,359 | $$2M | +99,840 | +19.5% | 12Q | SEC ↗ |
| 15 | MORGAN STANLEY | 503,860 | $$2M | +181,699 | +56.4% | 24Q | SEC ↗ |
| 16 | STATE STREET CORP | 428,787 | $$2M | +290,556 | +210.2% | 23Q | SEC ↗ |
| 17 | UBS Group AG | 318,797 | $$1M | +254,292 | +394.2% | 15Q | SEC ↗ |
| 18 | VANGUARD FIDUCIARY TRUST CO | 284,886 | $$1M | +127,506 | +81.0% | 2Q | SEC ↗ |
| 19 | RENAISSANCE TECHNOLOGIES LLC | 281,200 | $$1M | +6,000 | +2.2% | 19Q | SEC ↗ |
| 20 | NORTHERN TRUST CORP | 240,599 | $$883K | +190,479 | +380.0% | 23Q | SEC ↗ |
| 21 | VANGUARD PORTFOLIO MANAGEMENT LLC NEW | 193,920 | $$712K | — | +0.0% | 1Q | SEC ↗ |
| 22 | MARSHALL WACE, LLP | 190,692 | $$700K | -168,214 | -46.9% | 3Q | SEC ↗ |
| 23 | Connor, Clark & Lunn Investment Manage | 125,606 | $$461K | +16,521 | +15.1% | 3Q | SEC ↗ |
| 24 | GOLDMAN SACHS GROUP INC | 120,834 | $$443K | -115,635 | -48.9% | 15Q | SEC ↗ |
| 25 | Hillsdale Investment Management Inc. NEW | 81,400 | $$299K | — | +0.0% | 1Q | SEC ↗ |
| 26 | Bank of New York Mellon Corp NEW | 68,187 | $$250K | — | +0.0% | 1Q | SEC ↗ |
| 27 | Sixth Street Partners Management Compa NEW | 67,622 | $$248K | — | +0.0% | 1Q | SEC ↗ |
| 28 | CHARLES SCHWAB INVESTMENT MANAGEMENT I NEW | 67,622 | $$248K | — | +0.0% | 1Q | SEC ↗ |
| 29 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 64,500 | $$237K | +11,000 | +20.6% | 17Q | SEC ↗ |
| 30 | Squarepoint Ops LLC NEW | 59,540 | $$219K | — | +0.0% | 1Q | SEC ↗ |
| 31 | PANAGORA ASSET MANAGEMENT INC NEW | 47,574 | $$175K | — | +0.0% | 1Q | SEC ↗ |
| 32 | Mariner, LLC NEW | 45,261 | $$166K | — | +0.0% | 1Q | SEC ↗ |
| 33 | Nuveen, LLC NEW | 37,023 | $$136K | — | +0.0% | 1Q | SEC ↗ |
| 34 | DIMENSIONAL FUND ADVISORS LP | 35,210 | $$129K | — | +0.0% | 2Q | SEC ↗ |
| 35 | Invesco Ltd. NEW | 34,742 | $$128K | — | +0.0% | 1Q | SEC ↗ |
| 36 | Cerity Partners LLC | 32,875 | $$121K | — | +0.0% | 8Q | SEC ↗ |
| 37 | State of Wyoming NEW | 32,862 | $$121K | — | +0.0% | 1Q | SEC ↗ |
| 38 | Graham Capital Management, L.P. | 29,770 | $$109K | +18,427 | +162.5% | 2Q | SEC ↗ |
| 39 | DEUTSCHE BANK AG NEW | 27,824 | $$102K | — | +0.0% | 1Q | SEC ↗ |
| 40 | WELLS FARGO & COMPANY/MN NEW | 25,325 | $$93K | — | +0.0% | 1Q | SEC ↗ |
| 41 | BANK OF AMERICA CORP /DE | 23,875 | $$88K | -32,650 | -57.8% | 15Q | SEC ↗ |
| 42 | PRICE T ROWE ASSOCIATES INC /MD NEW | 22,758 | $$84K | — | +0.0% | 1Q | SEC ↗ |
| 43 | CITADEL ADVISORS LLC | 22,554 | $$83K | -101,824 | -81.9% | 2Q | SEC ↗ |
| 44 | RHUMBLINE ADVISERS NEW | 22,074 | $$81K | — | +0.0% | 1Q | SEC ↗ |
| 45 | Vanguard Global Advisers, LLC | 16,210 | $$59K | +11,574 | +249.7% | 2Q | SEC ↗ |
| 46 | ExodusPoint Capital Management, LP NEW | 15,475 | $$57K | — | +0.0% | 1Q | SEC ↗ |
| 47 | BARCLAYS PLC | 14,529 | $$53K | +5,929 | +68.9% | 18Q | SEC ↗ |
| 48 | NEW YORK STATE COMMON RETIREMENT FUND NEW | 14,200 | $$52K | — | +0.0% | 1Q | SEC ↗ |
| 49 | HSBC HOLDINGS PLC | 13,652 | $$50K | — | +0.0% | 12Q | SEC ↗ |
| 50 | JPMORGAN CHASE & CO | 13,538 | $$50K | +13,476 | +21735.5% | 23Q | SEC ↗ |
Recent Activity
New Positions (20)
| Holder | Shares | Value |
|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 6,475,882 | $$24M |
| Soleus Capital Management, L.P. | 3,378,378 | $$12M |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 766,095 | $$3M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 193,920 | $$712K |
| Hillsdale Investment Management Inc | 81,400 | $$299K |
| Bank of New York Mellon Corp | 68,187 | $$250K |
| CHARLES SCHWAB INVESTMENT MANAGEMEN | 67,622 | $$248K |
| Sixth Street Partners Management Co | 67,622 | $$248K |
| Squarepoint Ops LLC | 59,540 | $$219K |
| PANAGORA ASSET MANAGEMENT INC | 47,574 | $$175K |
| Mariner, LLC | 45,261 | $$166K |
| Nuveen, LLC | 37,023 | $$136K |
| Invesco Ltd. | 34,742 | $$128K |
| State of Wyoming | 32,862 | $$121K |
| DEUTSCHE BANK AG | 27,824 | $$102K |
| WELLS FARGO & COMPANY/MN | 25,325 | $$93K |
| PRICE T ROWE ASSOCIATES INC /MD | 22,758 | $$84K |
| RHUMBLINE ADVISERS | 22,074 | $$81K |
| ExodusPoint Capital Management, LP | 15,475 | $$57K |
| NEW YORK STATE COMMON RETIREMENT FU | 14,200 | $$52K |
Sold Out (16)
| Holder | Prev Shares | Prev Value |
|---|---|---|
| EcoR1 Capital, LLC | 947,049 | $$3M |
| SUSQUEHANNA INTERNATIONAL GROUP, LL | 267,788 | $$983K |
| JANE STREET GROUP, LLC | 192,963 | $$708K |
| TD Asset Management Inc | 160,652 | $$590K |
| MANUFACTURERS LIFE INSURANCE COMPAN | 70,546 | $$259K |
| HRT FINANCIAL LP | 58,699 | $$215K |
| XTX Topco Ltd | 57,190 | $$210K |
| Focus Partners Wealth | 50,007 | $$184K |
| OMERS ADMINISTRATION Corp | 32,700 | $$120K |
| PRUDENTIAL FINANCIAL INC | 17,420 | $$64K |
| Point72 Asset Management, L.P. | 16,329 | $$60K |
| Diametric Capital, LP | 11,980 | $$44K |
| NINE MASTS CAPITAL Ltd | 11,699 | $$43K |
| AMERICAN CENTURY COMPANIES INC | 10,294 | $$38K |
| CALDWELL SUTTER CAPITAL, INC. | 1,000 | $$4K |
| IFP Advisors, Inc | 1 | $$0K |
Biggest Increases (20)
| Holder | Added | Change % | Total Shares |
|---|---|---|---|
| ORBIMED ADVISORS LLC | +2,815,315 | +25.8% | 13,724,571 |
| BlackRock, Inc. | +1,475,615 | +458.4% | 1,797,501 |
| Kynam Capital Management, LP | +822,536 | +51.6% | 2,415,087 |
| VANGUARD CAPITAL MANAGEMENT LLC | +779,039 | +63.3% | 2,009,445 |
| ADAR1 Capital Management, LLC | +748,075 | +489.5% | 900,900 |
| GEODE CAPITAL MANAGEMENT, LLC | +539,404 | +178.3% | 841,862 |
| MILLENNIUM MANAGEMENT LLC | +462,256 | +120.8% | 844,993 |
| SPHERA FUNDS MANAGEMENT LTD. | +461,493 | +82.7% | 1,019,832 |
| STATE STREET CORP | +290,556 | +210.2% | 428,787 |
| UBS Group AG | +254,292 | +394.2% | 318,797 |
| NORTHERN TRUST CORP | +190,479 | +380.0% | 240,599 |
| MORGAN STANLEY | +181,699 | +56.4% | 503,860 |
| VANGUARD FIDUCIARY TRUST CO | +127,506 | +81.0% | 284,886 |
| ACADIAN ASSET MANAGEMENT LLC | +99,840 | +19.5% | 611,359 |
| TWO SIGMA INVESTMENTS, LP | +69,743 | +7.6% | 993,369 |
| Graham Capital Management, L.P. | +18,427 | +162.5% | 29,770 |
| Connor, Clark & Lunn Investment Man | +16,521 | +15.1% | 125,606 |
| JPMORGAN CHASE & CO | +13,476 | +21735.5% | 13,538 |
| CITIGROUP INC | +13,028 | +260560.0% | 13,033 |
| Vanguard Global Advisers, LLC | +11,574 | +249.7% | 16,210 |
Biggest Decreases (9)
| Holder | Reduced | Change % | Total Shares |
|---|---|---|---|
| MARSHALL WACE, LLP | -168,214 | -46.9% | 190,692 |
| GOLDMAN SACHS GROUP INC | -115,635 | -48.9% | 120,834 |
| CITADEL ADVISORS LLC | -101,824 | -81.9% | 22,554 |
| BANK OF AMERICA CORP /DE | -32,650 | -57.8% | 23,875 |
| Qube Research & Technologies Ltd | -3,307 | -20.1% | 13,110 |
| SBI Securities Co., Ltd. | -2,619 | -99.2% | 22 |
| FMR LLC | -380 | -6.3% | 5,629 |
| CWM, LLC | -119 | -17.2% | 573 |
| Optiver Holding B.V. | -16 | -80.0% | 4 |